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Tripodi L.,HIGH-TECH | Matters-Kammerer M.,TU Eindhoven | Schafer H.,University of Siegen | Bolivar P.H.,University of Siegen | And 3 more authors.
Procedia Engineering | Year: 2012

Miniaturized, low cost and easy to use devices able to carry out analysis in the chemical or biomedical domains could extend the use of imaging and spectroscopic techniques, now widely exploited in the professional sector, to applications in the consumer market or in the domain of point-of-care diagnostics. While a number of advanced techniques based on infrared or optical radiation show great potential for use in highly sensitive biosensors, the use of another part of the electromagnetic spectrum, the so called terahertz band (100 GHz - 3 THz), promise the creation of new devices with the capability of carrying out spectroscopy and imaging at the same time, even on samples located in an opaque package. In this paper we present our results demonstrating the possibility to create a miniaturized terahertz imaging and spectroscopy system that can be mass produced at low cost using well-known and robust commercial technologies such as CMOS and 3D chip-scale packaging (3D-CSP). The presented device is able to produce and detect a broadband signal from 20 GHz to 280 GHz with a dynamic range of 44 dB at 140 GHz. © 2012 The Authors. Published by Elsevier Ltd. Source


Tripodi L.,Philips | Hu X.,Uppsala University | Hu X.,ABB | Gotzen R.,MicroTEC Gesellschaft fur Mikrotechnologie MbH | And 6 more authors.
IEEE Transactions on Microwave Theory and Techniques | Year: 2012

This paper describes a frequency multiplier able to emit a broadband signal with a frequency range from 70 GHz up to at least 170 GHz. The device is composed of a nonlinear transmission line (NLTL) implemented in commercial CMOS 65-nm technology and an off-chip Vivaldi antenna. These two elements are packaged together with a 3-D chip-scale packaging technology. Characterization of the whole device and of the standalone NLTL is presented at frequencies up to 170 GHz. © 2012 IEEE. Source


Merkle T.,Sony | Merkle T.,Fraunhofer Institute for Applied Solid State Physics | Gotzen R.,MicroTEC Gesellschaft fur Mikrotechnologie MbH | Choi J.-Y.,Sony | And 3 more authors.
IEEE Transactions on Microwave Theory and Techniques | Year: 2015

A novel all-in-polymer multichip module (MCM-P) process is presented for applications at D-band (110-170 GHz). The unique manufacturing approach is an additive 3-D printing approach based on a gradual photo-induced polymerization in the z-direction with metallized interconnection layers in between. The package design integrates a broadband waveguide transition nearly covering the entire D-band. Different transmission-line types for chip interconnections were characterized up to 170 GHz. In prior research, a millimeter-wave monolithic integrated circuit (MMIC) amplifier using a 50-nm metamorphic high electron-mobility transistor technology was designed. In this study, the co-design with the package is presented. The amplifier MMIC was bond-wire free embedded in an MCM-P test structure and contacted with coplanar measurement probes. A gain of more than 20 dB within 100-170 GHz was measured. Based on those results, an amplifier MCM-P with integrated waveguide transitions of size 6 mm × 4.5 mm was developed. The MCM-P was surface mounted on a printed circuit board and flipped into a waveguide test fixture. A gain of more than 20 dB remained from 125 to 155 GHz with an input and output matching better than 10 dB. © 2014 IEEE. Source


Grant
Agency: Cordis | Branch: H2020 | Program: IA | Phase: WATER-1a-2014 | Award Amount: 2.37M | Year: 2015

The proposed project will deploy for the first time a new imaging cytometer platform capable of detecting minute quantity of micro-organisms in industrial and environmental waters. The platform is based on the integration of proprietary technologies available to the consortium partners: an automatic water concentration cartridge combined with a microfluidic cell will provide an adequate sample to a newly designed fluorescence image cytometer whose readings will be recorded and processed using a proper software interface. It will be validated for quantifying Legionella and Escherichia coli (E. coli) population within 120 minutes from obtaining the sample, overcoming in this way the main disadvantage of traditional methods used in laboratories, i.e. long time-to results which can currently last up to 12 days in the case of Legionella and 1 day for E. coli. The targeted detection limit will be 10-100 cells/L and 5-20 cells/100 mL for Legionella and E.coli, respectively. Also, the new imaging cytometer will have a portable form, a size similar to a smart-phone, which will increase its versatility and widen the possibilities of onsite applications. The relevance of the project is clear when one thinks about the high risk of legionellosis in some specific industrial environments, such as cooling waters, evaporative condensers and air conditioning systems and the fact that E. coli is one of the faecal pollution index commonly analyzed for monitoring the presence of waterborne pathogens and hence the quality of bathing waters. From a market perspective, more than 7 million of Legionella analyses are performed annually in Europe while E. coli level is included in all bathing water regulations in different EU countries. CYTO-WATER clearly falls into HORIZON 2020 topic WATER-1-2014/2015: Bridging the gap: from innovative water solutions to market replication and addresses Water Framework Directive (2000/60/EC) and in the Bathing Water Directive (2006/7/EC).


Gotzen R.,MicroTEC Gesellschaft fur Mikrotechnologie MbH | Scherag F.,Albert Ludwigs University of Freiburg | Sulz G.,Fraunhofer Institute for Physical Measurement Techniques | Schmidt M.,Micropelt GmbH | And 4 more authors.
17th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2013 | Year: 2013

We present a device platform for point-of-care testing of whole blood samples. It enables the determination of the viral load of blood on a processor-controlled device platform. For the analysis process two disposable cartridges carrying the fluidic and a media module are placed together in one device platform. In order to verify the operational capability of the device the following sample viruses were selected for the project and hoarded in two bio banks: Cytomegalovirus (CMV), varicella-zoster virus (VZV), herpes simplex virus (HSV) 1 and 2 and Epstein-Barr virus (EBV). Copyright © (2013) by the Chemical and Biological Microsystems Society All rights reserved. All rights reserved. Source

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