MicroTEC Gesellschaft fur Mikrotechnologie MbH

Duisburg, Germany

MicroTEC Gesellschaft fur Mikrotechnologie MbH

Duisburg, Germany

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Merkle T.,Sony | Merkle T.,Fraunhofer Institute for Applied Solid State Physics | Gotzen R.,MicroTEC Gesellschaft fur Mikrotechnologie MbH | Choi J.-Y.,Sony | And 3 more authors.
IEEE Transactions on Microwave Theory and Techniques | Year: 2015

A novel all-in-polymer multichip module (MCM-P) process is presented for applications at D-band (110-170 GHz). The unique manufacturing approach is an additive 3-D printing approach based on a gradual photo-induced polymerization in the z-direction with metallized interconnection layers in between. The package design integrates a broadband waveguide transition nearly covering the entire D-band. Different transmission-line types for chip interconnections were characterized up to 170 GHz. In prior research, a millimeter-wave monolithic integrated circuit (MMIC) amplifier using a 50-nm metamorphic high electron-mobility transistor technology was designed. In this study, the co-design with the package is presented. The amplifier MMIC was bond-wire free embedded in an MCM-P test structure and contacted with coplanar measurement probes. A gain of more than 20 dB within 100-170 GHz was measured. Based on those results, an amplifier MCM-P with integrated waveguide transitions of size 6 mm × 4.5 mm was developed. The MCM-P was surface mounted on a printed circuit board and flipped into a waveguide test fixture. A gain of more than 20 dB remained from 125 to 155 GHz with an input and output matching better than 10 dB. © 2014 IEEE.


Grant
Agency: European Commission | Branch: H2020 | Program: RIA | Phase: ICT-26-2014 | Award Amount: 3.23M | Year: 2015

The SAPHELY project focuses on the development and the preclinical validation of a nanophotonic-based handheld point-of-care (POC) analysis device for its application to the minimally-invasive early diagnosis of diseases, with a focus in cancer. Disease identification will be based in the fast (<5 minutes), ultra-sensitive (sub-pM) and label-free detection of novel highly-specific microRNA (miRNA) biomarkers, using a small volume of whole blood (<100 L). This POC analysis device, which will have a low cost (envisaged cost < 3000), will significantly help in the implementation of mass screening programs, with the consequent impact on clinical management, reducing also costs of treatments, and increasing survival rates. The ultra-high sensitivity required for the direct detection of miRNA biomarkers present in the bloodstream will be achieved by using a novel sensing amplification technique. This technique is based in the use of molecular beacon capture probes with an attached high index nanoparticle, so that the hybridization events are translated into the displacement of these nanoparticles from the sensor surface. The use of this self-amplification technique avoids the use of complex PCR-based amplification methods or labelling processes, which are difficult to implement on-chip. The cost, size and weight reduction required for deploying an affordable handheld POC device will be achieved by using a novel power-based readout scheme for photonic bandgap sensing structures where the use of expensive, bulky and heavy tuneable lasers and spectrometers is avoided. Special attention will be paid within the SAPHELY project to explore the potential deployment and commercialisation of the analysis device, by means of the involvement of relevant academic and industrial partners, as well as end users.


Reinhold I.,XaarJet AB | Reinhold I.,KTH Royal Institute of Technology | Thielen M.,XaarJet AB | Voit W.,XaarJet AB | And 5 more authors.
EMPC-2011 - 18th European Microelectronics and Packaging Conference, Proceedings | Year: 2011

Inkjet printing of planar and via (through-hole) electrical interconnections is developed to be incorporated into a roll-to-roll manufacturing line. The specific roll-to-roll machine uses rotary RMPD® technology, self-alignment of bare LED dies, and inkjet printing of the electrical connections to the LEDs dies. The key problem to be solved is the inkjet printing of electrical connections through via holes with vertical walls Xaar126-50pL industrial inkjet printheads were used to print silver nano particle ink at 0.1 m/s to connect through LED vias of 90 μm diameter and up to 50 μm depth. While high throughput sintering techniques are desirable for the specific roll-to-roll machine standard convection oven sintering was applied for the proof of principle described here. Sintering at temperatures as low as 135 °C for 30 min prevented damage to the substrate and LED dies and yielded electrical connections that allowed to drive LEDs with 20 mA at 3V under emission of bright green light. © 2011 IMAPS.


Reinhold I.,XaarJet AB | Reinhold I.,KTH Royal Institute of Technology | Thielen M.,XaarJet AB | Voit W.,XaarJet AB | And 5 more authors.
Materials Research Society Symposium Proceedings | Year: 2011

Despite the availability of many high-volume and low-cost manufacturing processes for LED-based lighting applications, relying mainly on fixed patterns such as LED-backlights and RGB-pixelated displays, novel applications, such as "mood lighting" or interior wall displays call for more complicated and shaped LED arrangements. The presented work is based of a novel roll-to-roll (R2R) process to adaptively and cost-efficiently generate LED arrangements on RMPD® substrates. Inkjet printing of planar and though-hole electrical interconnections is of high importance to the process, as it provides a fully digital way of interconnecting devices electrically, accounting for the actual position of the component and spatially provide different ink film thicknesses. Xaar's industrial inkjet printheads are used to dispense defined volumes of 50 pL of a silver nanoparticle ink in order to provide high reliability and good positioning accuracy while maintaining low satellite drop densities. Specific printing strategies are investigated at a print speed of 0.1 m/s to allow for a reliable electrical connection in case of up to 50 μm deep via connections to the buried component. Due to the low glass-transition nature of the underlying substrates, low sintering temperatures are required to preserve the mechanical properties of the substrate. Low temperature oven sintering yielding sufficient conductivity to drive a current of 40 mA will be discussed. © 2011 Materials Research Society.


Grant
Agency: European Commission | Branch: H2020 | Program: RIA | Phase: ICT-26-2014 | Award Amount: 3.39M | Year: 2015

The diagnosis and management of acute Sepsis is a critical area where fast and accurate results can translate into life changing health outcomes for individuals. The overall aim of RAIS is to develop a new point-of-care label-free microarray platform and validate it for quantifying levels of specific Sepsis biomarkers. The approach uses a novel interferometric technique ultimately capable of providing very large arrays of tests. Specific objectives and activities include: (i) an optical microarray reader based on a disruptive proprietary design combining interferometric lens-free microscopy and proximity CCD or CMOS image sensing; (ii) a microarray plate, in a proper microfluidic cartridge, consisting of a transparent slide with a novel nano-structured surface geometry to increase the detection sensitivity and covered by specific receptors to capture bio-markers; (iii) their integration in a portable and battery powered label free microarray platform potentially capable of measuring more than 1 million bio-targets simultaneously. The developed technology will be capable to detect micro-ribonucleic acids (microRNAs), interleukins and other specific proteins associated to Sepsis using a few microliters of blood or serum samples, in a concentration of a few pg/ml, within 30 minutes (sample to result) and at a cost per patient of less than 50. In this way, patients will be put on the right treatment more rapidly, potentially reducing the Sepsis mortality rate of more than 70%, with estimated cost savings of more than 10 billion per year as a consequence of shorter hospital stays, reduced use of unnecessary drugs and lower associated insurance bills. The technical approach, targeted device, application and the addressed market sector are perfectly in line with the call H2020-ICT-2014-1 - Photonics KET - Biophotonics for screening of diseases: Mobile, low-cost point-of-care screening devices for reliable, fast and non- or minimally-invasive detection of diseases.


Gotzen R.,MicroTEC Gesellschaft fur Mikrotechnologie mbH | Scherag F.,Albert Ludwigs University of Freiburg | Sulz G.,Fraunhofer Institute for Physical Measurement Techniques | Schmidt M.,Micropelt GmbH | And 4 more authors.
17th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2013 | Year: 2013

We present a device platform for point-of-care testing of whole blood samples. It enables the determination of the viral load of blood on a processor-controlled device platform. For the analysis process two disposable cartridges carrying the fluidic and a media module are placed together in one device platform. In order to verify the operational capability of the device the following sample viruses were selected for the project and hoarded in two bio banks: Cytomegalovirus (CMV), varicella-zoster virus (VZV), herpes simplex virus (HSV) 1 and 2 and Epstein-Barr virus (EBV). Copyright © (2013) by the Chemical and Biological Microsystems Society All rights reserved. All rights reserved.


Merkle T.,Sony | Merkle T.,Fraunhofer Institute for Applied Solid State Physics | Gotzen R.,MicroTEC Gesellschaft fur Mikrotechnologie MbH
IEEE Transactions on Components, Packaging and Manufacturing Technology | Year: 2015

Board level integration of novel all-in-polymer 3-D printed multichip modules process (MCM-P) at millimeter-wave frequencies is presented. The modules were manufactured using additive 3-D printing technologies based on mask-defined gradual photopolymerization in the z -direction. A lead frame structure was introduced resulting in a quad-flat no-lead footprint of 0.5-mm pitch. The front-side of the modules integrated transmission lines of the centered stripline type for interconnecting embedded millimeter-wave monolithic integrated circuits up to D -band (110-170 GHz). Broadband surface mount transitions from the MCM-P front-side interconnection layers to a high-frequency printed circuit board (PCB) were investigated. Dual channel test modules were characterized in back-to-back configuration, representing the integration needs of millimeter-wave multiple-input-multiple-output systems. The de-embedded PCB transition exhibited an insertion loss of less than 2 dB up to 75 GHz and less than 1 dB up to 60 GHz with a return loss better than 10 dB. © 2014 IEEE.


Tripodi L.,HIGH-TECH | Matters-Kammerer M.,TU Eindhoven | Schafer H.,University of Siegen | Bolivar P.H.,University of Siegen | And 3 more authors.
Procedia Engineering | Year: 2012

Miniaturized, low cost and easy to use devices able to carry out analysis in the chemical or biomedical domains could extend the use of imaging and spectroscopic techniques, now widely exploited in the professional sector, to applications in the consumer market or in the domain of point-of-care diagnostics. While a number of advanced techniques based on infrared or optical radiation show great potential for use in highly sensitive biosensors, the use of another part of the electromagnetic spectrum, the so called terahertz band (100 GHz - 3 THz), promise the creation of new devices with the capability of carrying out spectroscopy and imaging at the same time, even on samples located in an opaque package. In this paper we present our results demonstrating the possibility to create a miniaturized terahertz imaging and spectroscopy system that can be mass produced at low cost using well-known and robust commercial technologies such as CMOS and 3D chip-scale packaging (3D-CSP). The presented device is able to produce and detect a broadband signal from 20 GHz to 280 GHz with a dynamic range of 44 dB at 140 GHz. © 2012 The Authors. Published by Elsevier Ltd.


Tripodi L.,Philips | Hu X.,Uppsala University | Hu X.,ABB | Gotzen R.,MicroTEC Gesellschaft fur Mikrotechnologie MbH | And 6 more authors.
IEEE Transactions on Microwave Theory and Techniques | Year: 2012

This paper describes a frequency multiplier able to emit a broadband signal with a frequency range from 70 GHz up to at least 170 GHz. The device is composed of a nonlinear transmission line (NLTL) implemented in commercial CMOS 65-nm technology and an off-chip Vivaldi antenna. These two elements are packaged together with a 3-D chip-scale packaging technology. Characterization of the whole device and of the standalone NLTL is presented at frequencies up to 170 GHz. © 2012 IEEE.


Grant
Agency: European Commission | Branch: H2020 | Program: IA | Phase: WATER-1a-2014 | Award Amount: 2.37M | Year: 2015

The proposed project will deploy for the first time a new imaging cytometer platform capable of detecting minute quantity of micro-organisms in industrial and environmental waters. The platform is based on the integration of proprietary technologies available to the consortium partners: an automatic water concentration cartridge combined with a microfluidic cell will provide an adequate sample to a newly designed fluorescence image cytometer whose readings will be recorded and processed using a proper software interface. It will be validated for quantifying Legionella and Escherichia coli (E. coli) population within 120 minutes from obtaining the sample, overcoming in this way the main disadvantage of traditional methods used in laboratories, i.e. long time-to results which can currently last up to 12 days in the case of Legionella and 1 day for E. coli. The targeted detection limit will be 10-100 cells/L and 5-20 cells/100 mL for Legionella and E.coli, respectively. Also, the new imaging cytometer will have a portable form, a size similar to a smart-phone, which will increase its versatility and widen the possibilities of onsite applications. The relevance of the project is clear when one thinks about the high risk of legionellosis in some specific industrial environments, such as cooling waters, evaporative condensers and air conditioning systems and the fact that E. coli is one of the faecal pollution index commonly analyzed for monitoring the presence of waterborne pathogens and hence the quality of bathing waters. From a market perspective, more than 7 million of Legionella analyses are performed annually in Europe while E. coli level is included in all bathing water regulations in different EU countries. CYTO-WATER clearly falls into HORIZON 2020 topic WATER-1-2014/2015: Bridging the gap: from innovative water solutions to market replication and addresses Water Framework Directive (2000/60/EC) and in the Bathing Water Directive (2006/7/EC).

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