MICROJET Corporation

Shiojiri, Japan

MICROJET Corporation

Shiojiri, Japan

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Yagai S.,Chiba University | Yagai S.,Japan Science and Technology Agency | Okamura S.,Chiba University | Nakano Y.,Chiba University | And 10 more authors.
Nature Communications | Year: 2014

π-Conjugated compounds that exhibit tunable luminescence in the solid state under external mechanical stimuli have potential applications in sensors and imaging devices. However, no rational designs have been proposed that impart these mechano-responsive luminescent properties to π-conjugated compounds. Here we demonstrate a strategy for mechano-responsive luminescent materials by imparting amphiphilic and dipolar characteristics to a luminescent π-conjugated system. The oligo(p-phenylenevinylene) luminophore with a didodecylamino group at one end and a tri(ethylene glycol) ester group at the other end yields segregated solid structures by separately aggregating its hydrophobic and hydrophilic moieties. The segregated structures force the molecules to align in the same direction, thereby generating a conflict between the side-chain aggregation and dipolar stabilization of the π-system. Consequently, these metastable solid structures can be transformed through mechanical stimulation to a more stable structure, from a π-Ï € stacked aggregate to a liquid crystal and further to a crystalline phase with variable luminescence. © 2014 Macmillan Publishers Limited. All rights reserved.


Yamaguchi S.,Tokyo University of Agriculture and Technology | Yamaguchi S.,Microjet Corporation | Yamaguchi S.,Osaka University | Ueno A.,Microjet Corporation | And 4 more authors.
Biofabrication | Year: 2012

The inkjet ejection technology used in printers has been adopted and research has been conducted on manufacturing artificial tissue by patterning cells through micronozzle ejection of small droplets containing multiple cells. However, stable injection of cells has proven difficult, owing to the frequent occurrence of nozzle clogging. In this paper, a piezoelectric inkjet head constructed with a glass capillary that enabled viewing of the nozzle section was developed, the movement of cells ejected from the nozzle tip was analyzed, and a method for stably ejecting cells was verified. A pull-push ejection method was compared with a push-pull ejection method regarding the voltage waveform applied to the piezoelectric element of the head. The push-pull method was found to be more suitable for stable ejection. Further, ejection of one cell per droplet was realized by detecting the position of the cell in the nozzle section and utilizing these position data. Thus, a method for more precise patterning of viable cells at desired position and number was established. This method is very useful and promising not only for biofabrication, 3D tissue construction, cell printing, but also for a number of biomedical application, such as bioMEMS, lab on a chip research field. © 2012 IOP Publishing Ltd.


Fujita S.,Japan National Institute of Advanced Industrial Science and Technology | Onuki-Nagasaki R.,Japan National Institute of Advanced Industrial Science and Technology | Fukuda J.,Japan National Institute of Advanced Industrial Science and Technology | Fukuda J.,University of Tsukuba | And 5 more authors.
Lab on a Chip - Miniaturisation for Chemistry and Biology | Year: 2013

Super-dense transfected cell microarrays (TCMs) were created by a piezoelectric inkjet printer on a glass substrate that had been grafted with poly(ethylene glycol) (PEG). The micro-spots that contained plasmid and extra-cellular matrix (ECM) protein were separated from one another by a hydrophilic barrier generated by PEG. We successfully constructed the densest TCMs with spots of 50 μm in diameter and 150 μm in pitch. © The Royal Society of Chemistry.


Trademark
Microjet Corporation | Date: 2012-01-31

Chemical processing machines and apparatus, namely, power-operated dispensers for chemical processing, mixing and blending machines, sorting machines, granulating machines, extracting machines, reacting machines, namely, micro chemical reactors, separating machines, dissolving machines; food preparation machines, beverage preparation machines; woodworking machines, namely, wood polishing machines, wood grinding machines and wood engraving machines; printing machines and apparatus, namely, printing presses, industrial printing machines, production printing machines, and printing heads for industrial printing machines for industrial purposes; machines and apparatus, namely, glass working machines for manufacturing glassware; painting machines and apparatus, namely, inkjet painting machines, automatic sprayers for electrostatic painting, and spray guns for painting; packaging machines, wrapping machines; machines and apparatus for manufacturing plastic or resin goods, namely, machines for plastic working, extrusion machines for plastic working, and plastic jet molding machines; machines and apparatus for manufacturing rubber goods, namely, rubber forming machines and rubber mixing machines; dish washing machines for industrial purposes; sprayers for disinfecting, insecticides and deodorants and not for agricultural purposes. Photocopy machines; laboratory apparatus and instruments, namely, electronic dispensers for laboratory use, droppers sold empty for laboratory use, apparatus, namely, bioreactors, processing machines, dispensers, injectors, samplers for culturing tissues or cells for laboratory use; optical apparatus and instruments, namely, microscopes, micro-optical lenses; telecommunication devices and apparatus, namely, transmitters for telecommunication, telephone apparatus, electric installations for the remote control of industrial operations, television apparatus for projection purposes, video recorders; electronic machines, apparatus and their parts, namely, computers, computer software for use in database management, computer software for use in laboratory instrument operation; computer software for use in laboratory information management; computer software for use in laboratory management, namely, test initiation, sample tracking, analysis, and reporting of test results; computer software for use in laboratory database management and integration; computer software for use in chemical processing; computer software for use with printers, computer software for use in the field of experimentation, research and development of ink-jet printer heads and machines with ink-jet type printer heads, computer software for use in the field of cell and tissue processing; computer peripheral devices, integrated circuits, large scale integrated circuits, printed circuits, interface boards for computers. Aerosol dispensers for medical purposes; medical fluid injectors; sprayers for cleaning gums and teeth used in dentists offices during dental procedures; feeding pumps for medical purposes; droppers for administering medication, sold empty.


Patent
Microjet Corporation | Date: 2013-04-24

A discharge system includes: a head unit including discharge heads that discharge a liquid material from nozzle openings that are communication with cavities onto a target by changing the internal pressure of the cavities using piezo elements; a viscosity estimating unit that estimates the viscosity of the liquid material by sucking the liquid material from first vessels that hold the liquid material into the cavities; and a waveform control unit that controls the voltage applied to the piezo elements according to the estimated viscosity of the liquid material.


Patent
Microjet Corporation | Date: 2011-02-09

A discharge device includes a discharge head that discharges a liquid material from a nozzle opening connected to the cavity by varying the internal pressure of a cavity using an actuator. The discharge head includes a monitoring portion provided between the cavity and the nozzle opening and the discharge device further includes a detection apparatus that detects the number and/or form of the particle-like bodies included in the liquid material in the monitoring portion of the discharge head and a control unit that drives the actuator according to the detection result of the detection unit to change the state of the particle-like bodies included in the liquid material of the monitoring portion.


Patent
Microjet Corporation | Date: 2015-03-04

A discharge system 1 includes: a head unit (10) including discharge heads (11) that discharge a liquid material (25) from nozzle openings (14) that are communication with cavities (13) onto a target (51) by changing the internal pressure of the cavities (13) using piezo elements (12); a viscosity estimating unit (81) that estimates the viscosity of the liquid material (25) by sucking the liquid material (25) from first vessels (21) that hold the liquid material (25) into the cavities (13); and a waveform control unit (82) that controls the voltage applied to the piezo elements (12) according to the estimated viscosity of the liquid material (25).


Patent
Microjet Corporation | Date: 2013-01-16

A discharge device (1) includes a discharge head (10) that discharges a liquid material (50) from a nozzle opening (11) connected to the cavity (14) by varying the internal pressure of a cavity (14) using an actuator (6). The discharge head (10) includes a monitoring portion (12) provided between the cavity (14) and the nozzle opening (11) and the discharge device (1) further includes a detection apparatus (7) that detects the number and/or form of the particle-like bodies (51) included in the liquid material (50) in the monitoring portion (12) of the discharge head (10) and a control unit (74) that drives the actuator (6) according to the detection result (7a) of the detection unit (7) to change the state of the particle-like bodies (51) included in the liquid material (50) of the monitoring portion (12).


Patent
Microjet Corporation | Date: 2010-02-16

There is provided a discharge head including: a tubular member that includes a flat portion with an oblate shape where a cross-section of a tube path extends in a first direction, the tubular member being formed so that the flat portion includes a first wall that is flat and has an actuator attached to an outside thereof and the flat portion becomes a cavity with an internal volume thereof varying due to displacement of the first wall; and a nozzle opening that is provided at one end of the tubular member and discharges a liquid substance due to variation in the internal volume of the cavity.


Patent
Microjet Corporation | Date: 2011-12-28

There is provided a discharge head (10) including: a tubular member (20) that includes a flat portion (23) with an oblate shape where a cross-section of a tube path extends in a first direction (100x), the tubular member being formed so that the flat portion (23) includes a first wall (23a) that is flat and has an actuator (6) attached to an outside thereof and the flat portion becomes a cavity (13) with an internal volume thereof varying due to displacement of the first wall (23a); and a nozzle opening (11) that is provided at one end of the tubular member (20) and discharges a liquid substance (9) due to variation in the internal volume of the cavity (13).

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