Michigan State University is a public research university located in East Lansing, Michigan, United States and is the first land-grant institution that was created to serve as a model for future land-grant colleges in the country under the 1862 Morrill Act.MSU pioneered the studies of packaging, hospitality business, supply chain management, and telecommunication. It is considered to be one of America's Public Ivy universities, which recognizes top public universities in the United States.Following the introduction of the Morrill Act, the college became coeducational and expanded its curriculum beyond agriculture. Today, MSU is the seventh-largest university in the United States , with 49,300 students and 2,954 faculty members.MSU's Division I sports teams are called the Spartans. They compete in the Big Ten Conference in all sports. MSU's football team won the Rose Bowl in 1954, 1956, 1988 and 2014 and boasts six national championships. Its men's basketball team won the NCAA National Championship in 1979 and 2000 and is currently enjoying a streak of six Final Four appearances over the last 13 seasons. MSU men's ice hockey won national titles in 1966, 1986 and 2007. Cross country has historically been Michigan State's most successful sport, especially during a four-decade period spanning roughly 1930–1970 during which the Spartans won eight NCAA championships and numerous other conference and national titles. Wikipedia.
Michigan State University | Date: 2016-08-30
The disclosure relates to a process and related article for functionalizing a porous membrane by contacting the membrane with a polyacid polymer at low pH to stably adsorb a polyacid layer on the membrane pore surface. The resulting functionalized membrane is characterized by a high density of free acid groups, resulting in a higher specific capacity for its intended application. The process allows functionalization of porous membranes in a very simple, one-step process. Such functional membranes may find multiple uses, including rapid, selective binding of proteins for their purification or immobilization.
Michigan State University | Date: 2016-09-09
Systems and methods are described for using microplasmas in 3D printing to deposit materials, remove materials, or modify the properties of materials deposited on a given substrate surface. The resulting microplasma-based 3D printing enables the integration of different types of materials into the same 3D printed structure that is not possible with current technology.
Michigan State University | Date: 2016-05-26
The disclosure relates to materials and articles that provide an irreversible history of compression forces and torques experienced by the materials and articles. The disclosure relates more particularly to an multiple impact level detection assembly as well as related articles and methods. The multiple impact level detection assembly provides distinct impact patterns depending on the impact force and direction (for torqueing motions) received by the detection assembly. The detection assembly can be incorporated into a variety of articles and used in a variety of settings, for example to monitor personal safety in a protective garment such as a helmet. The detection assembly incorporates an impact detection medium (e.g., a plurality of microcapsules with an indicator therein), which can serve as an irreversible means for detecting impact on the assembly via a relief substrate incorporated into the assembly.
Michigan State University | Date: 2016-08-03
A method for forming a compound on a substrate is provided. The method includes depositing a composition onto a surface of a substrate; illuminating the composition and the substrate with pulsed energy; melting the substrate and decomposing the composition simultaneously; and forming a compound on the substrate. A first component of the compound is derived from the substrate and a second component of the compound is derived from the composition.
Michigan State University, Wisconsin Alumni Research Foundation and University of British Columbia | Date: 2017-03-08
The invention relates to nucleic acids encoding a feruloyl-CoA:monolignol transferase and the feruloyl-CoA:monolignol transferase enzyme that enables incorporation of monolignol ferulates, for example, including p-coumaryl ferulate, coniferyl ferulate, and sinapyl ferulate, into the lignin of plants.
Brandizzi F.,Michigan State University
Nature Reviews Molecular Cell Biology | Year: 2013
Coat protein complex I (COPI) and COPII are required for bidirectional membrane trafficking between the endoplasmic reticulum (ER) and the Golgi. While these core coat machineries and other transport factors are highly conserved across species, high-resolution imaging studies indicate that the organization of the ER-Golgi interface is varied in eukaryotic cells. Regulation of COPII assembly, in some cases to manage distinct cellular cargo, is emerging as one important component in determining this structure. Comparison of the ER-Golgi interface across different systems, particularly mammalian and plant cells, reveals fundamental elements and distinct organization of this interface. A better understanding of how these interfaces are regulated to meet varying cellular secretory demands should provide key insights into the mechanisms that control efficient trafficking of proteins and lipids through the secretory pathway. © 2013 Macmillan Publishers Limited. All rights reserved.
Johnson A.W.,Michigan State University
Trends in Neurosciences | Year: 2013
Animals use current, past, and projected future states of the organism and the world in a finely tuned system to control ingestion. They must not only deal effectively with current nutrient deficiencies, but also manage energy resources to meet future needs, all within the constraints of the mechanisms of metabolism. Many recent approaches to understanding the control of ingestive behavior distinguish between homeostatic mechanisms concerned with energy balance, and hedonic and incentive processes based on palatability and reward characteristics of food. In this review, I consider how learning about environmental cues influences homeostatic and hedonic brain signals, which may lead to increases in the affective taste properties of food and desire to over consume. Understanding these mechanisms may be critical for elucidating the etiology of the obesity epidemic. © 2013 Elsevier Ltd.
Robison A.J.,Michigan State University
Trends in Neurosciences | Year: 2014
Although it has been known for decades that hippocampal calcium/calmodulin (CaM)-dependent protein kinase II (CaMKII) plays an essential role in learning and memory consolidation, the roles of CaMKII in other brain regions are only recently being explored in depth. A series of recent studies suggest that CaMKII dysfunction throughout the brain may underlie myriad neuropsychiatric disorders, including drug addiction, schizophrenia, depression, epilepsy, and multiple neurodevelopmental disorders, perhaps through maladaptations in glutamate signaling and neuroplasticity. I review here the structure, function, subcellular localization, and expression patterns of CaMKII isoforms, as well as recent advances demonstrating that disturbances in these properties may contribute to psychiatric disorders. © 2014 Elsevier Ltd.
Thoennessen M.,Michigan State University
Reports on Progress in Physics | Year: 2013
Currently about 3000 different nuclei are known with about another 3000-4000 predicted to exist. A review of the discovery of the nuclei, the present status and the possibilities for future discoveries are presented. © 2013 IOP Publishing Ltd.
Agency: NSF | Branch: Continuing grant | Program: | Phase: Track 3 INFEWS | Award Amount: 1.14M | Year: 2017
Emilio F. Moran
Hydropower dams have been an important part of worldwide energy production, but they also have resulted in substantial negative environmental and social outcomes. This project will study a new way to think about hydropower, one that looks not just at energy production as the goal, but as an integrated system that can generate ecological, economic, and societal benefits beyond electricity. The study will model scenarios to assess how hydropower technologies can be deployed in new ways, such as through enhancing production of food by applying river sediments on cropland as fertilizer, or by changing hydropower technology toward smaller dams and in-stream turbines to reduce negative outcomes on river ecology and fish productivity. Along with the training of students and postdocs, a web-based decision support system will be developed to inform stakeholders about alternative hydropower designs and locations, offer options to increase benefits to stakeholders, and serve as a lasting legacy for policy makers, scientists, and local institutions in managing their food, water and energy resources. The scenarios for redesigned hydropower will potentially transform how hydropower is viewed, replacing a top-down approach that mandates a single-minded focus on maximizing energy production with a bottom-up approach informed by the complexity interlinking the food, energy, and water systems. The project will generate innovative solutions that will improve the acceptability of hydropower development in the US, Europe, and across the world.
An estimated 3,700 major dams are currently either planned or under construction worldwide, and they will continue to play significant roles in energy production in the foreseeable future. This studys goal is to develop innovative solutions for hydropower-- not just to produce energy for the national grid, but woven into the surrounding food, water, and institutional systems. The team includes hydroengineers, hydrogeologists, climatologists, biologists and social scientists working in tandem to offer transformative solutions for hydropower development while ensuring that social and environmental benefits outweigh costs. The research teams will assess land cover change to understand deforestation risk in and around dams, and identify agricultural areas that can benefit from sediment application. Coupled hydrological and climate models, linked to land cover changes in different landscape and socio-ecological settings, including international collaborations, will identify better hydropower solutions including ways to move sediments to farms and/or locations for in-stream turbines. Institutional and governance analysis will examine the multi-tiered dimensions that intrude upon the way civil society benefits from hydropower. The project will generate innovative solutions to produce renewable energy from hydropower, increase food production, and lessen negative environmental and social impacts that have reduced the acceptability of hydropower development, in the US, Europe and across the world.