Rajasekar M.,MGMCRI |
Ramakrishnan K.,MGMCRI |
Ganesh Babu C.P.,MGMCRI |
Research Journal of Pharmaceutical, Biological and Chemical Sciences | Year: 2015
Staphylococci, especially Methicillin-resistant Staphylococcus aureus (MRSA) isolates became one of the potent nosocomial pathogen to cause significant mortality and morbidity. Individuals colonized by MRSA acts as reservoir and also disseminate infections to others. Especially in case of intensive-care patients, MRSA worsens their morbidity and increases the mortality and also creates financial burden. Thus this study was aimed to detect the percentage of MRSA carriers in various anatomical sites among in-patients, out-patients and in health-care workers A total of 900 swabs were taken from all the three groups of study population from different anatomical sites. Samples were inoculated on to Mannitol screening agar and Staphylococcus aureus isolates were identified. MRSA isolates were confirmed by various phenotypic methods like Cefoxitin disc diffusion method, by inoculating onto Oxacillin and vancomycin screening agars. Mupirocin susceptibility and Vancomycin MIC were confirmed by appropriate methods. Total of 14 MRSA carries were identified out of 900 swabs(450 individuals). MRSA carrier rate was identified as 3.1%(14/450) in our tertiary care setting. In-patient occupies the highest of 5.3% and followed by Health-care workers 4%. Eighty eight percent of in-patients MRSA carriers and 10% of Health-care MRSA carriers were identified by anterior nares sampling. Mupirocin susceptibility for all 14 MRSA isolates by Kirby Bauer disc diffusion method showed 100% susceptibility. Vancomycin MIC by agar dilution and E-test methods showed MIC value of =1μg/mL. Though it is always controversial whether to screen for MRSA carriers among health-care professionals and others, we have done this study as an active tool to prevent our hospital acquired infections due to MRSA. Among in-patients regular screening and decolonization will strongly bring down the morbidity and mortality. Anterior nares are found to be ideal site to identify MRSA carriers among our study population.
Sudar Codi R.,MGMCRI |
Khan S.,MGMCRI |
Manimekalai K.,MGMCRI |
International Journal of Pharma and Bio Sciences | Year: 2015
Compare the rationality of prescriptions between private practitioners and physicians of a tertiary care hospital. A prospective study was done by reviewing 150 prescriptions each of private practitioners and physicians of a tertiary care hospital over a period of 2 months. The rationality assessment was done using the method adopted by Gajjar. Collected data entered and analyzed using Microsoft office Excel 2010 computer software. Statistical tests were applied and p < 0.05 was considered as statistically significant.120 prescriptions were rationally prescribed by physicians of a tertiary care hospital. 28 were semi rational and only 2 prescriptions were irrational. 46 prescriptions of the private practitioners were rational, 88 semi rational and 16 were irrational (P < 0.001). Private practitioners prescribe more irrational prescriptions. Our studies on the prescribing pattern of various sectors needed to make the doctors aware of the irrational drug use. Also, the art of prescription writing and the need for rational prescribing should be stressed during the medical school.
PubMed | JIPMER and MGMCRI
Type: Journal Article | Journal: Indian journal of anaesthesia | Year: 2016
A tertiary care 1000 bedded hospital contains more than 10,000 pieces of equipment worth approximately 41 million USD, while the power cords supplied along with the imported equipment do not comply with country-specific norms. Moreover, the local vendors procure power cords with type D/M plug to complete installation and also on-site electrical safety test is not performed. Hence, this project was undertaken to evaluate the electrical safety of all life-saving equipment purchased in the year 2013, referring to the guidelines of International Electrotechnical Commission 62353, the Association for the Advancement of Medical Instrumentation (AAMI) and National Fire Protection Association (NFPA)-99 hospital standard for the analysis of protective earth resistance and chassis leakage current. This study was done with a measuring device namely electrical safety analyser 612 model from Fluke Biomedical.