MGMC and RI

Puducherry, India

MGMC and RI

Puducherry, India

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Dash S.,MGMC and RI | Mahapatro A.K.,MGMC and RI
International Journal of Pharma and Bio Sciences | Year: 2014

Takayasu's areritis is a chronic inflammatory oblitarative arteritis of unknown aetiology. Anaesthesia in these patients is complicated by uncontrolled hypertension, hypoperfusion of organs and difficulty in BP monitoring due to stenosis and aneurismal dilatation of arteries. This case report is about successful management of a 27 yrs old primigragida with known case of Takayasu's arteritis, Seizure disorder and Hypothyroidism at 38 wks of gestation on treatment who underwent an emergency caesarean section under spinal anaesthesia. The intraoperative and postoperative period was uneventful. Uniqueness of this case is maintenance of adequate mean arterial pressure in a hypothyroid patient with TA by adequate preloading and SAB with low dose local anaesthetic with a narcotic (fentanyl).


Dash S.,MGMC and RI
International Journal of Pharma and Bio Sciences | Year: 2014

To evaluate the effect of adding midazolam to bupivacaine to prolong the analgesia characteristics of brachial plexus block. After pre- anaesthetic assessment all the patients were premedicated with diazepam 0.1mg/kg orally one hour before the surgery. Patients were randomly divided into group1 & 2. Group -1 patients received supraclavicular brachial plexus block with 30ml of 0.5% bupivacaine & group -2 patients received a mixture of 30ml of 0.5% bupivacaine & midazolam 50μg/kg body weight. On arrival in the operating room, standard base line vital signs readings were recorded. Intra -operatively HR, BP, oxygen saturation & sedation, time of establishment of sensory & motor block were recorded in all patients. Post-operatively HR, BP, sensory & motor block, pain score & sedation score, time of requirement of rescue analgesia were assessed at 0,30min,2hr,6hrs,12 hrs & 24 hrs in all patients. Demographic variables were comparable. There was no significant difference in monitoring of intraoperative & post-operative Vital signs (HR, SBP, DBP, MAP & oxygen saturation). Post-operative sedation score, pain score, requirement of rescue analgesia, sensory & motor block were significantly less in group-2 (p -value-<0.05). Conclusion-addition of midazolam to bupivacaine in brachial plexus block produces early onset of sensory and motor block, increased sedation score intraoperatively & prolongs postoperative analgesia.


Perumal C.,MGMC and RI | Chowdhury P.S.,MGMC and RI | Ananthakrishnan N.,MGMC and RI | Nayak P.,MGMC and RI | Gurumurthy S.,MGMC and RI
Urology Annals | Year: 2015

Introduction: Lower urinary tract symptoms in men, over age of 50 years is suggestive of benign prostatic enlargement (BPE). Different alpha-blockers have been evaluated for the treatment of benign prostatic hyperplasia for over last 30 years. This study was conducted in a tertiary care institution during the period of year between June 2011 and August 2013 to compare the effect of naftopidil and tamsulosin in reducing the obstructive and irritable symptoms of BPE.Subjects and Methods: A prospective randomized comparative study was carried on 60 patients of BPE by assigning half of them to treatment with tamsulosin and rest with naftopidil. Pre- and post-treatment uroflowmetry (UFM), post-void residue (PVR), International Prostate Symptoms Score (IPSS), were obtained at 15 and 30 days after starting treatment.Results: The age of patients ranged from 51 to 78. At base line there was no statistical difference between UFM parameter, PVR and IPSS in the two groups. UFM and PVR showed significantly better response at both intervals with naftopidil. Comparison of IPSS showed better improvement in Group A both at 15 and 30 days. It was seen that the obstructive symptoms showed a significantly better response with tamsulosin and symptoms of irritability was seen better response with naftopidil.Conclusion: It was seen that during the period of follow-up of 30 days naftopidil had a better effect on UFM, PVR, IPSS compared with tamsulosin. In general, obstructive symptoms showed better improvement in tamsulosin and irritative symptoms showed better improvement in naftopidil.


Samal S.,MGMC and RI | Ghose S.,MGMC and RI | Pallavee P.,MGMC and RI | Porkkodi P.,MGMC and RI
Journal of Clinical and Diagnostic Research | Year: 2015

Cervical pregnancy is a rare form of ectopic pregnancy with potential grave consequences occurring in approximately 1:9,000 deliveries. It is life-threatening as the pregnancy is implanted in the endocervical canal and the trophoblast can penetrate through the cervical wall and into the uterine blood supply resulting in catastrophic haemorrhage. Historically, the treatment had been hysterectomy because of the considerable risk of life-threatening haemorrhage, but in the recent past various conservative management modalities have been applied to preserve fertility. Here, we report a case of successful (both medical and surgical) management of cervical ectopic pregnancy in a young woman. A 29-year-old, gravid 2, para1 and living 1 with previous caesarean section had presented with mild bleeding per vagina for 5 days following 7 weeks of amenorrhoea. Past menstrual, medical, surgical and family history were unremarkable except the previous caesarean section. On examination vital signs were normal but pelvic examination revealed a distended cervix with bulky uterus, without anyadnexal mass or tenderness and no cervical motion tenderness. Further transvaginal sonography showed a live cervical gestation of 7 weeks and 4 days and serum beta-HCG value of 1,03,113mIU/ml. Patient received conservative approach with combination of intraamniotic potassium chloride and methotrexate and suction curettage. Due to conservative approach emergency hysterectomy and blood transfusion was avoided. © 2015, Journal of Clinical and Diagnostic Research. All rights reserved.


PubMed | MGMC and RI
Type: Journal Article | Journal: Indian journal of endocrinology and metabolism | Year: 2012

Two short siblings who were brought for evaluation of short stature are described with emphasis on availability of resources in the diagnosis and management of the cause of short stature in them.


Annamary K.,Indira Gandhi Institute of Dental science | Prathima G.,Indira Gandhi Institute of Dental science | Sajeev R.,Indira Gandhi Institute of Dental science | Kayalvizhi G.,Indira Gandhi Institute of Dental science | And 2 more authors.
Journal of Clinical and Diagnostic Research | Year: 2016

Introduction: Dental setting plays an important role in child’s behavior and cooperation to the planned dental treatment. Adding attractive colours to the dental environment and by incorporating colourful equipments can make the child feel good and be at ease. This study tries to convey the relationship between colours and dental anxiety among children. Aim: To evaluate the colour preference to emotions in relation to children’s age, gender and anxiety level. Materials and Methods: A total of 382 children aged 6-12 years were randomly selected from schools in and around Puducherry. Modified dental anxiety scale was recorded by a calibrated examiner. Each question was scored from one (not anxious) to five (extremely anxious); such that the total score ranges from 5 to 25, wherein a score of 15 or more was considered to be anxious. Based on this, children were divided into anxious and non-anxious groups. All the children were provided with eight different coloured crayon pencils and were asked to shade two car oon emoticons indicating happiness and sadness with their preferred colour. Values were tabulated and statistically analyzed to evaluate the association between the variables using Z test, Chi-square, Chi-square goodness of fit and odds ratio. (p≤0.05 was considered statistically significant). Results: Among 382 children, 77% (294) were graded as anxious and 23% (88) as non- anxious. For positive emotion (happiness), 31.2% (119) children preferred blue followed by pink 29.3% (112). For negative emotion (sadness), 52.1% (199) of children preferred black and 46.9% (179) preferred red. Association between colour and emotion was highly significant (p= 0.005). Conclusion: From the colours preferred by the children in our study, it can be concluded that colours like blue and pink in the dental set-up could enhance a positive attitude while black and red could develop a negative outlook in their mind. © 2016, Journal of Clinical and Diagnostic Research. All rights reserved.


Akshaya Kumar M.,MGMC and RI
International Journal of Pharma and Bio Sciences | Year: 2013

To assess the correlation between insulin resistance and impaired glucose tolerance in PCO patients and also to evaluate IR and altered lipid profile in them. A prospective study was carried out from Feb. 2006 to Aug. 2007 on total of 75 patients. Out of them 40 patients were taken as cases having clinical and USG features of PCOS and 35 patients were taken as control having no features of PCOS. Fasting serum insulin, blood sugar, 2hr PGBS testosterone and lipid profile measured in both study & control group. PCOS is more prevalent in younger age groups. Average distribution of age in both groups was 23.6 ± 4 and 25.09 ± 4.5 respectively. Oligomenorrhoea is more common (60%) than secondary amenorrhoea (25%) in PCOS. Hyperandrogenism presents commonly as hirsutism (62.5%) and acne (35%). BMI was >25 in 40% of cases and 20% of controls.17.5% of PCOS women had impaired fasting and 2hr PGBS but none of them had frank diabetes. The mean fasting insulin value in PCOS was significantly higher than that of controls (i.e., 18.64 ± 9.33 vs. 8.59 ± 3.03). The fasting glucose to insulin ratio was < 4.5 in 52.5% of cases and > 4.5 in 91.4 % in controls. Primary infertility was common in 76.2% of cases. There were no significant lipid profile abnormalities in both groups. Hyperinsulinemia and insulin resistance are commonly associated with PCOS. Patients with IR have higher incidence of IGT hence as a prophylactic measure all patients with PCOS should be screened for insulin resistance and followed thereafter to prevent development of frank diabetes.


Mahapatro A.K.,MGMC and RI | Ghose S.,MGMC and RI
International Journal of Pharma and Bio Sciences | Year: 2014

Objective-The purpose of this study was to find out prevalence, risk factors, mode of delivery, & perinatal out come in Meconium stained amniotic fluid (MSAF) during delivery At term pregnancy. Study design-this retrospective study was conducted in MGMC&RI, puducherry with womens at 37-42 wks of gestation those were meconium stained amniotic fluid during labour & delivery. Different maternal outcome like mode of delivery, indication for operative delivery & perinatal outcome in relation to low apgar score, neonatal intensive care unit(Nicu) admission, meconium aspiration syndrome(MAS),perinatal asphyxia & neonatal death were analysed. Result- Prevalence of meconium stained amniotic fluid during labour & delivery was 12.42% during study period. Most of the cases were primigravida (85%) with mean age & gestational age of-24.99 yrs & 39.44 wks respectively. Postdated pregnancy (32.85%) & oligo hydramnios(18.57%) were the two major risk factor for meconium stained amniotic fluid. Caesarean section (C.S) was the most common mode of delivery (84.28%) due to fetal distress & thick meconium stained liquor(40.71%).20% of cases were admitted to Nicu for low apgar score at birth.50% of nicu admission were due to MAS & its complication. There were two(7.14% of nicu admission) neonatal death due to MAS & its complication inspite of early active intervention in our study. Conclusion-Meconium stained amniotic fluid during labour & delivery is definite direct & indirect evidence of fetal distress(FD).Grading of meconium stained amniotic fluid was a severe adverse effect in perinatal outcome. Instead of early active intervention there were early neonatal death in our study. So the outcome of meconium stained amniotic fluid during labour & delivery is unpredictable.


PubMed | MGMC and RI
Type: Journal Article | Journal: Journal of human reproductive sciences | Year: 2015

There are limited causes of surgically treatable male infertility. Lymphangiocele of scrotum is a very rare condition particularly in adult life. Lymphangiocele causing infertility is further rare and not reported in English literature so far. We report an extremely rare case of lymphangiocele in a 29 years male presenting with male infertility that improved after surgery.


PubMed | MGMC and RI
Type: Journal Article | Journal: Urology annals | Year: 2015

Lower urinary tract symptoms in men, over age of 50 years is suggestive of benign prostatic enlargement (BPE). Different alpha-blockers have been evaluated for the treatment of benign prostatic hyperplasia for over last 30 years. This study was conducted in a tertiary care institution during the period of year between June 2011 and August 2013 to compare the effect of naftopidil and tamsulosin in reducing the obstructive and irritable symptoms of BPE.A prospective randomized comparative study was carried on 60 patients of BPE by assigning half of them to treatment with tamsulosin and rest with naftopidil. Pre- and post-treatment uroflowmetry (UFM), post-void residue (PVR), International Prostate Symptoms Score (IPSS), were obtained at 15 and 30 days after starting treatment.The age of patients ranged from 51 to 78. At base line there was no statistical difference between UFM parameter, PVR and IPSS in the two groups. UFM and PVR showed significantly better response at both intervals with naftopidil. Comparison of IPSS showed better improvement in Group A both at 15 and 30 days. It was seen that the obstructive symptoms showed a significantly better response with tamsulosin and symptoms of irritability was seen better response with naftopidil.It was seen that during the period of follow-up of 30 days naftopidil had a better effect on UFM, PVR, IPSS compared with tamsulosin. In general, obstructive symptoms showed better improvement in tamsulosin and irritative symptoms showed better improvement in naftopidil.

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