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Navi Mumbai, India

Kumar R.,MGM Dental College and Hospital | Khambete N.,CSMSS Dental College and Hospital | Priya E.,Saveetha Dental College and Hospital
Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology

This case report presents successful immediate mandibular third molar autotransplantation to replace the nonrestorable mandibular first molar. In this case, after the extraction of the nonrestorable tooth, the donor molar with incomplete root formation was autotransplanted into the recipient site after the atraumatic extraction. A long-term follow-up of 2 years revealed that the tooth was fixed in its socket without residual inflammation, masticatory function was satisfactory and without discomfort; the tooth was not mobile, no pathologic condition was apparent radiographically, the lamina dura appeared normal and the tooth showed radiographic evidence of root growth, and pulpal regeneration and the depth of the pocket, gingival contour, and gingival color were all normal. The purpose of this case report is to demonstrate the clinical application of autotransplantation as a future option of permanent restoration without implants, orthodontic space closure, or partial denture. © 2013 Elsevier Inc. All rights reserved. Source

Doddanna S.J.,Teerthanker Mahaveer University | Patel S.,MGM Dental College and Hospital | Sundarrao M.A.,Pacific Dental College and Research Center | Veerabhadrappa R.S.,Teerthanker Mahaveer University
Indian Journal of Dental Research

Background and Objectives: Plants as sources of medicinal compounds have continued to play a predominant role in the maintenance of human health since ancient times. Even though several effective antifungal agents are available for oral candida infections, the failure is not uncommon because isolates of Candida albicans may exhibits resistance to the drug during therapy. The present study was conducted to evaluate the antimicrobial effects of few plant extracts on Candida albicans. An additional objective was to identify an alternative, inexpensive, simple, and effective method of preventing and controlling Candida albicans. Materials and Methods: Fine texture powder or paste form of leaves was soaked in sterile distilled water and 100% ethyl alcohol, which were kept in refrigerator at 4°C for 24 h. Then filtrates were prepared and kept in a hot air oven to get a black shining crystal powder/paste form. Stock solutions of plant extracts were inoculated on petri plates containing species of Candida albicans and incubated at 25 ± 2°C for 72 h. Results: Alcoholic curry leaves showed the maximum zone of inhibition on Candida albicans followed by aqueous tea leaves. The other plant extracts like alcoholic onion leaves, alcoholic tea leaves, alcoholic onion bulb, alcoholic aloe vera, and alcoholic mint leaves also inhibited the growth of Candida albicans but lesser extent. Conclusion: The present study renders few medicinal plants as an alternative medicines to the field of dentistry which can be used adjunct to conventional therapy of oral candidasis. Source

Background and Objective: There is a substantial magnitude of data implicating the role of interleukin-23 (IL-23) in the initiation and progression of periodontal disease. The main aim of this study was to evaluate the levels of IL-23 in the gingival crevicular fluid of systemically healthy subjects in periodontal health and disease. In addition, we explored the effectiveness of periodontal interventional therapy on the levels of IL-23 in subjects with chronic periodontitis to obtain a deeper insight into the possible role of IL-23 in three separate periodontal conditions in three different populations. Material and Methods: In this study, 54 individuals, satisfying the study inclusion and exclusion criteria, were recruited. They were categorically divided, on the basis of gingival index, probing pocket depth and relative attachment loss, into three groups: Group 1 (patients with a clinically healthy periodontium, n = 18); Group 2 (patients with gingivitis, n = 18); and Group 3a (patients with chronic periodontitis, n = 18). Samples taken from all 18 subjects of Group 3a, 3 mo after the initial therapy, constituted Group 3b. All clinical parameters were recorded at baseline and 3 mo after scaling and root planing. Gingival crevicular fluid samples were obtained in which the IL-23 concentration was measured using ELISA. Results: The highest mean IL-23 concentration in gingival crevicular fluid was found for Group 3a (16448.69 pg/mL) and the lowest for Group 1 (2565.28 pg/mL). The mean IL-23 concentrations in Group 2 (5425 pg/mL) and Group 3b (6272.22 pg/mL) lay between the maximum and minimum values. This implies a positive correlation between the gingival crevicular fluid IL-23 concentration and relative attachment loss (p < 0.05). Conclusion: A noteworthy increase in the gingival crevicular fluid IL-23 concentration was seen that was proportional to the amount of periodontal tissue damage. As the IL-23 concentration in gingival crevicular fluid is directly proportional to the severity of the periodontal affliction, it can be speculated that IL-23 has a possible role in the pathogenesis of periodontal disease. © 2013 John Wiley & Sons A/S. Source

Vibha,JKK Nataraja Dental College and Hospital | Swain N.,MGM Dental College and Hospital
Journal of Oral and Maxillofacial Surgery, Medicine, and Pathology

Oral submucous fibrosis is a chronic, progressive, crippling disorder with a high potential of malignant transformation. Even after 6 decades of its description as a separate entity, no concrete treatment is available due to its multi-modal pathogenesis. Thus, adding to the morbidity associated with it. Current article is an attempt to compile the available drugs, so as to aid early intervention of the disease. © 2013 . Source

Introduction One of the essential factors for successful root canal therapy is elimination of bacterial contaminants using an effective root canal chemical irrigant such as sodium hypochlorite which inherently possesses certain disadvantages like irritation to periapical tissues, staining of the instruments, burning of surrounding tissues etc. The aim of the study was to explore newer irrigant agents which would probably be as effective or more and at the same time less irritating to the tissues than sodium hypochlorite. Our search included two such agents, propolis and miswak. Methods The study was performed on 40 infected primary teeth (20 male and 20 female patients). The subjects were divided into 4 groups of 10 children. Group 1 received 3% sodium hypochlorite as irrigating solution, group 2 received 12.5% alcoholic extract of miswak, group 3 received 11% alcoholic extract of propolis and group 4, 0.9% saline. We used the antimicrobial activity of sodium hypochlorite as gold standard for comparing the activities of both propolis and miswak. We collected pre- and post-irrigation samples using sterile paper points. Samples were cultured on tryptose soya agar at a temperature of 37°C for 24-48 hours. The colonies were counted with a digital colony counter. For the statistical analysis, we used the unpaired t test at level of significance 0.05 and the ANOVA test for analysis of variance. Results The differences in pre- and post- irrigation values were calculated for each group, the greatest difference being seen in group 1 (95.549%) followed by group 2 (89.794%), group 3 (34.735%) and group 4 (28.087%). When comparing the results between groups, there was no statistically significant difference between groups 3 and 4. Conclusions The statistically analyzed results suggested that miswak could be a good natural substitute to sodium hypochlorite, while propolis showed results comparable to those of the negative control. © GERMS 2011. Source

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