Mg Science Institute

Ahmadābād, India

Mg Science Institute

Ahmadābād, India

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Patel U.H.,Sardar Patel University | Barot R.A.,Sardar Patel University | Patel B.D.,Nv Patel Pure And Applied Science College | Shah D.A.,Mg Science Institute | Modh R.D.,Gujarat Arts and Science College
Agris On-line Papers in Economics and Informatics | Year: 2012

N-substituted pyrrole derivatives block HIV fusion. Docking used for virtual screening of database and for the prediction of the strongest binders based on various scoring functions. Docking studies were carried out on different pyrrole derivatives for better anti-HIV-1 activity which is important for the development of a new class of inhibitors. Protein-ligand interaction plays an important role in structural based drugs design. In our research we have selected different receptor which shows anti-HIV-1 activity. The receptors were docked with different pyrrole derivatives and the energy value obtained. Our study reveals that the highest energy values observed for all the three ligands are with 3MNW: for 2-Amino-1-(4-Iodophenyl)-oxo-4, 5-dihydro-1H-pyrrole-3-carboxylic acid ethyl ester energy value is -265.9, for 2-Amino-1-(4-Fluoro-phenyl)-oxo-4, 5-dihydro-1H-pyrrole-3-carboxylic acid ethyl ester energy value is -228.23 and for 2-Amino-1-(4-Methoxy-phenyl)-oxo-4, 5-dihydro-1Hpyrrole-3-carboxylic acid ethyl ester energy value is -227.13. From this we can say that Iodo pyrrole derivative shows high interaction energy compared to other Fluoro and methyl derivatives. By synthesizing few more analogous, we can further improve the interaction energy values and hence better analogous derivatives can be predicted. © 2010.


Shah R.D.,Mg Science Institute | Jasinski J.P.,Keene State College
Acta Crystallographica Section E: Structure Reports Online | Year: 2010

In the title compound, C18H11ClN6, the pyrrole, pyrimidine and tetra-zole rings form a nearly planar fused trihetrocyclic system with an r.m.s. deviation of 0.0387 (13) Å, to which the 4-chloro-phenyl group and the phenyl group are substituted at the 7 and 9 positions, respectively. The dihedral angles between the pyrrole ring and the 4-chloro-phenyl and phenyl rings are 32.1 (4) and 7.87 (7)°, respectively. In the crystal, weak inter-molecular C - H⋯N and C - H⋯Cl hydrogen bonds link the mol-ecules into a layer parallel to the (001) plane. The layers are further connected by π-π stacking inter-actions [centroid-centroid distances: 3.8413 (8) and 3.5352 (8) Å]. Intra-molecular C - H⋯N hydrogen bonds are also present.


Baldaniya B.B.,Mg Science Institute | Jasinski J.P.,Keene State College
Acta Crystallographica Section E: Structure Reports Online | Year: 2010

In the title compound, C24H22N2O 4S, the central pyrimidine ring is significantly puckered, assuming a conformation inter-mediate between a boat and a screw boat. The nearly planar thia-zole ring (r.m.s. deviation = 0.0258 Å) is fused with the pyriamidine ring, making a dihedral angle of 9.83 (7)°. The carboxyl group is in an extended conformation with an anti-periplanar orientation with respect to the dihydropyrimidine ring. The benzene ring linked at the chiral C atom is perpendicular to the pyrimidine ring [dihedral angle = 85.21 (8)°] whereas the phenyl ring is nearly coplanar, making a dihedral angle of 13.20 (8)°. An intra-molecular C - H⋯S hydrogen bond is observed. The crystal packing is influenced by weak inter-molecular C - H⋯π inter-actions and π-π stacking between the thia-zole and phenyl rings [centroid-centroid distance = 3.9656 (10) Å], which stack the mol-ecules along the c axis.


Pandya C.V.,Mg Science Institute | Patel P.M.,P.A. College | Baluja K.L.,University of Delhi
Chinese Journal of Physics | Year: 2010

Theoretical studies of elastic electron scattering by a calcium atom have been made by employing a model complex optical potential (composed of static, exchange, polarization and absorption terms). The complex optical potential, free from any adjustable parameter, is treated exactly in a variable phase approach to yield scattering complex phase shifts and the differential scattering cross section in the intermediate energy region. The calculations were performed at electron impact energies 10, 60, and 100 eV. We report on the elastic, inelastic, and momentum transfer cross sections up to 500 eV and compare them with other results. The present method is quite simple in nature and is able to reproduce fairly well the experimental differential cross sections (DCS) and other cross sections in the present energy regions. © 2010 The Physical Society of the Republic of China.


Joseph J.K.,M. S. University of Baroda | Patel S.J.,M. S. University of Baroda | Bhatt N.Y.,Mg Science Institute
Journal of the Geological Society of India | Year: 2012

The Middle Jurassic rocks of the Kaladongar Formation well exposed in the Kaladongar Hill range of the Patcham Island and Kuar Bet of the Northern Kachchh comprises of ~450 m thick sequence of mixed siliciclasticcarbonate sediments intercalated with shales. These Mixed siliciclastic-carbonate sediments show wide variation in textural and mineralogical composition and represent genetically related six rock types: micritic sandstone, allochemic sandstone, sandy allochemic limestone, micrtic mudrock, sandy micrite and muddy micrite; which are highly bioturbated and show behaviourally diverse groups of trace fossils. Total 34 ichnogenera are identified, which includes, Arenicolites, Asterosoma, Beaconites, Bergaueria, Chondrites, Cochlichnus, Dactylophycus, Daedalus, Didymaulichnus, Diplocraterion, Gordia, Gyrochorte, Gyrolithes, Ichnocumulus, Laevicyclus, Lockeia, Margaritichnus, Monocraterion, Nereites, Ophiomorpha, Palaeophycus, Phoebichnus, Phycodes, Pilichnus, Planolites, Plug Shaped Form, Protovirgularia, Rhizocorallium, Scolicia, Skolithos, Taenidium, Teichichnus, Thalassinoides and Walcottia. These trace fossils are classified into six morphological groups namely, circular and elliptical structures; simple structures; branched structures; rosette structures; spreiten structures; and winding and meandering structures. These trace fossils are further group into eight assemblages which occurred together into mixed siliciclastic-carbonate sediments, include, Asterosoma assemblage, Gyrochorte assemblage, Rhizocorallium assemblage, Thalassinoides assemblage, Planolites-Palaeophycus assemblage, Phycodes assemblage, Ophiomorpha assemblage and Skolithos assemblage. The recurring pattern of these assemblages through the sequence displays the development of Skolithos and Cruziana ichnofacies and at places the mixed Skolithos-Cruziana ichnofacies which suggest a low wave and current energy conditions with intervening period of high wave and current energy conditions and an intermediate period of stressful environments, respectively. Sedimentological and ichnological data suggest that the deposition of the mixed siliciclastic-carbonate sediments of the Kaladongar Formation took place in the foreshore to offshore environment under fluctuating wave and current energy condition. © Geol. Soc. India.


Patel S.J.,M. S. University of Baroda | Joseph J.K.,M. S. University of Baroda | Bhatt N.Y.,Mg Science Institute
Journal of the Geological Society of India | Year: 2014

The middle Jurassic Goradongar Formation exposed in Goradongar hill represents a mixed siliciclasticcarbonate succession with shales and limestones. They contain a large number of well preserved trace fossils. Total 44 ichnospecies of 31 ichnogenera; representing diverse ethology, were grouped in five ichnoassemblages (Planolites, Palaeophycus, Gyrochorte, Rhizocorallium and Arenicolites assemblage). These recurring ichnoassemblages represent the Cruziana ichnofacies and occasionally a mixed Skolithos-Cruziana ichnofacies. Patterns of diversity and density of the trace fossils reveal changes in bathymetry, oxygen level, trophic level and the sub-strate conditions at the time of deposition. These paleoenvironment and palaeo-oceanography changes are co-relatable to world-wide Bathonian-Callovian (middle Jurassic) deposits. © 2014 Geological Society of India.


Varjani S.J.,Indian Institute of Science | Varjani S.J.,Kadi Sarva Vishwavidyalaya University | Upasani V.N.,Mg Science Institute
Bioresource Technology | Year: 2016

The aim of this work was to study the potential of an indigenous strain of Pseudomonas aeruginosa NCIM 5514, isolated from petroleum-polluted soil, for the biodegradation of crude petroleum oil. The isolate completely decolorized 2,6-dichlorophenol indophenol in 120 h when grown at (37 ± 1 °C), indicating its hydrocarbon utilizing nature. Ex situ biodegradation study was performed to find out quantitative utilization and biodegradation of paraffin(s) present in crude oil. When the culture was grown in Bushnell-Hass medium containing crude oil (3%, v/v) at 37 °C, 180 rpm for 60 days, the viscosity of the oil was reduced from 1883 cp to 1002 cp. Gravimetric and gas chromatographic analysis showed 61.03% and 60.63% of biodegradation of C8–C36+ hydrocarbons, respectively. These results indicated that the isolate has potential to be used for ex-situ and in-situ bioremediation of hydrocarbon pollutants and could have promising applications in petrochemical industry. © 2016 Elsevier Ltd


The crystal structure of N-[2,4,5-Trichlorophenyl] acetamide is optimized through semiempirical method to describe the influence of interactions on crystal packing using MOPAC2009 program. The electric dipole moment (μ) and molecular hyperpolarizabilities (β and γ) are computed by time dependent Hartree Fock (TDHF) method to inspect the non-linear optical behaviour of the material. The UV-VIS spectral study of material in 300-1100 nm wavelength range shows a wide transparency window which is the key requirement for the non-linear optical (NLO) property of the material. The experimentally measured value of second harmonic generation efficiency is 0.8 times to that of reference material potassium dihydrogen phosphate (KDP). The intramolecular charge transfer interaction results during the HOMO-LUMO transition observed from molecular orbital calculations. © (2014) Trans Tech Publications, Switzerland.


Brahmbhatt R.M.,Mg Science Institute | Bahuguna I.,Space Applications Center | Rathore B.P.,Space Applications Center | Kulkarni A.V.,Indian Institute of Science | And 3 more authors.
Journal of the Indian Society of Remote Sensing | Year: 2012

Glaciers are natural reservoirs of fresh water in frozen state and sensitive indicators of climate change. Among all the mountainous glaciated regions, glaciers of Himalayas form one of the largest concentrations of ice outside the Polar Regions. Almost all the major rivers of northern India originate from these glaciers and sustain perennial flow. Therefore, in view of the importance and role of the glaciers in sustaining the life on the Earth, monitoring the health of glaciers is necessary. Glacier's health is monitored in two ways (i) by mapping the change in extent of glaciers (ii) by finding variation in the annual mass balance. This paper has been discussed the later approach for monitoring the health of glaciers of Warwan and Bhut basins. Mass balance of glaciers of these two basins was determined based on the extraction of snow line at the end of ablation season. A series of satellite images of AWiFS sensor were analysed for extraction of snowline on the glaciers for the period of 2005, 2006 and 2007. The snow line at the end of ablation season is used to compute accumulation area ratio (AAR = Accumulation area/Glacier area) for each glacier of basins. An approach based on relationship of AAR to specific mass balance (computed in field) for glaciers of Basapa basin was employed in the present study. Mean of specific mass balance of individual glacier for the year 2005, 2006 and 2007 of Warwan basin was found to be -ve 0.19 m, -ve 0.27 m and -ve 0.2 m respectively. It is 0.05 m, -ve 0.11 m and -ve 0.19 m for Bhut basin. The analysis suggests a loss of 4.3 and 0.83 km3 of glacier in the monitoring period of 3 years for Warwan and Bhut basins respectively. The overall results suggest that the glaciers of Warwan basin and Bhut basins have suffered more loss of ice than gain in the monitoring period of 3 years. © 2011 Indian Society of Remote Sensing.


PubMed | Mg Science Institute and Kadi Sarva Vishwavidyalaya University
Type: | Journal: Bioresource technology | Year: 2016

The aim of this work was to study the potential of an indigenous strain of Pseudomonas aeruginosa NCIM 5514, isolated from petroleum-polluted soil, for the biodegradation of crude petroleum oil. The isolate completely decolorized 2,6-dichlorophenol indophenol in 120h when grown at (371C), indicating its hydrocarbon utilizing nature. Ex situ biodegradation study was performed to find out quantitative utilization and biodegradation of paraffin(s) present in crude oil. When the culture was grown in Bushnell-Hass medium containing crude oil (3%,v/v) at 37C, 180rpm for 60days, the viscosity of the oil was reduced from 1883cp to 1002cp. Gravimetric and gas chromatographic analysis showed 61.03% and 60.63% of biodegradation of C8-C36+ hydrocarbons, respectively. These results indicated that the isolate has potential to be used for ex-situ and in-situ bioremediation of hydrocarbon pollutants and could have promising applications in petrochemical industry.

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