Metropolitan University of Technology is a university in Chile. It is part of the Chilean Traditional Universities.The Metropolitan Technological University, better known by its acronym as UTEM, is a state institution of public higher education in Chile, founded on August 30, 1993 from the breakup of the University of Chile.It is one of the sixteen universities of the Consortium of Universities of the State of Chile, and belongs to the Council of Rectors of Chilean Universities.It has four branches, all located in the Metropolitan Region. Its head office is in the municipality of Santiago, being part of the old houses of the city street Eighteen declared Typical Zone by the National Monuments Council in the country.The UTEM is currently accredited by the National Accreditation Commission for three years, since its renovation in December 2013 to December 2016, adding elective area Bonding with Medio.2 as Figure 27. ª college Chilean as ranked AméricaEconomía, 1 October 2012, in 42 th place according to classification webométrica CSIC in July 2011,3 and 38th. according to the ranking of the Mercurio.4 in November 2011, is located on 1st place as the state university that best meets the Government Transparency Act.HistoryThe Metropolitan Technological University was founded from Santiago Professional Institute , which was formed in 1981 after the military regime dismembered the University of Chile, disappeared from IPUCH and other races that were left out of the University of Chile, such as: Construction, Architecture, Library, Cartography, Social Work and Design. The enactment of Law No. 19,239, was made in a ceremony led by the then rector of this study, and founder Luis Pinto prepulsor Faverio, Patricio Aylwin Azócar and Education Minister Jorge Arrate, at the Palace of La Moneda. On August 30, 1993 was published in the Official Journal of the Republic of Chile, the decree creating the Metropolitan Technological University , which constitutes the last of the Universities Council of Rectors.In the beginning, ie from 1993 to 2002, the UTEM starts delivering careers professional area of Engineering and the Social Area, becoming the state university which receives more young people in the first two income quintiles, from schools municipal and subsidized. In 2002, the UTEM begins to dictate the race of Criminology at the levels of technical , graduates Degree, which will have a major impact on subsequent attempts of institutional accreditation.The UTEM is a Chilean state university which receives every year about 1,500 students, has four offices in Santiago, with an area of 58,000 m².Doctor Honoris CausaThe March 20, 1996, the UTEM delivered its first title Doctor Honoris Causa former President Patricio Aylwin Azócar, in recognition of his outstanding professional and academic career, and her starring role in the history of our country.In May of that same year, the UTEM awarded its second title Doctor Honoris Causa Edgardo Henriquez Frodden doctor for his professional and academic career.The third Honoris Causa was awarded to former President Ricardo Lagos Escobar on April 30, 1998 and seven years later, as high honor was awarded to Dr. Gui Bonsiepe, recognized theoretical, industrial designer, international consultant and author required reading numerous texts in the discipline of design.In December 2010, the institution was accredited by CNA-Chile, but due to administrative problems and academic 9 only achieved by a year.10 However, appeared in the newspaper La Nacion audited annual balance sheet, showing positive number, thus giving clear progress of their term of crisis.11The November 15, 2011, a study by the Council of State of Chile Transparency ranked the UTEM as the state university that best met the Government Transparency Act, a 59.53% .12 On 29 December that year, the University got reaccreditation, this time for the period 2011 to 2013.13 reacreditarse again in December 2013 to December 2015.14 later, after an administrative appeal to CNA Chile, to extending their accreditation to 3 years until 29 December 2016.1The Metropolitan Technological University has 5 faculties distributed in Santiago, reaching an approximate 58,000 m² of buildings and landscaping area, has 53 Undergraduate Degree, 34 and 19 PSU login evening special income.His most extensive, and more number of students based, is the Faculty of Engineering which has an enrollment of nearly 4,000 students, ranking in the commune of Providencia, at the intersection of Avenida Greece Avenida José Pedro Alessandri . In it there recently constructed buildings that blend with the old buildings of the Hebrew Institute, which operated until about 1980.Likewise, the college acquired property and building in the town of Providence, for the operation of the Faculty of Management and Economics by the Dean, with capacity for over 2,000 students.Within Headquarters, is the Chapel of Gothic Revival style, located in the second courtyard of a historical Casona Colonial, which is open to the public on Heritage Day in Chile.Near the Central House are the Faculties of Humanities, Mapping and Architecture, in the municipality of Santiago. Wikipedia.
Bedhomme S.,CNRS Center of Evolutionary and Functional Ecology |
Perez Pantoja D.,Metropolitan University of Technology |
Bravo I.G.,IRD Montpellier
Molecular Ecology | Year: 2017
Plasmids are nucleic acid molecules that can drive their own replication in a living cell. They can be transmitted horizontally and can thrive in the host cell to high-copy numbers. Plasmid replication and gene expression consume cellular resources and cells carrying plasmids incur fitness costs. But many plasmids carry genes that can be beneficial under certain conditions, allowing the cell to endure in the presence of antibiotics, toxins, competitors or parasites. Horizontal transfer of plasmid-encoded genes can thus instantaneously confer differential adaptation to local or transient selection conditions. This conflict between cellular fitness and plasmid spread sets the scene for multilevel selection processes. We have engineered a system to study the short-term evolutionary impact of different synonymous versions of a plasmid-encoded antibiotic resistance gene. Applying experimental evolution under different selection conditions and deep sequencing allowed us to show rapid local adaptation to the presence of antibiotic and to the specific version of the resistance gene transferred. We describe the presence of clonal interference at two different levels: at the within-cell level, because a single cell can carry several plasmids, and at the between-cell level, because a bacterial population may contain several clones carrying different plasmids and displaying different fitness in the presence/absence of antibiotic. Understanding the within-cell and between-cell dynamics of plasmids after horizontal gene transfer is essential to unravel the dense network of mobile elements underlying the worldwide threat to public health of antibiotic resistance. © 2017 John Wiley & Sons Ltd.
Larsen J.M.,Metropolitan University of Technology |
Larsen J.M.,Technical University of Denmark
Immunology | Year: 2017
The microbiota plays a central role in human health and disease by shaping immune development, immune responses and metabolism, and by protecting from invading pathogens. Technical advances that allow comprehensive characterization of microbial communities by genetic sequencing have sparked the hunt for disease-modulating bacteria. Emerging studies in humans have linked the increased abundance of Prevotella species at mucosal sites to localized and systemic disease, including periodontitis, bacterial vaginosis, rheumatoid arthritis, metabolic disorders and low-grade systemic inflammation. Intriguingly, Prevotella abundance is reduced within the lung microbiota of patients with asthma and chronic obstructive pulmonary disease. Increased Prevotella abundance is associated with augmented T helper type 17 (Th17) -mediated mucosal inflammation, which is in line with the marked capacity of Prevotella in driving Th17 immune responses in vitro. Studies indicate that Prevotella predominantly activate Toll-like receptor 2, leading to production of Th17-polarizing cytokines by antigen-presenting cells, including interleukin-23 (IL-23) and IL-1. Furthermore, Prevotella stimulate epithelial cells to produce IL-8, IL-6 and CCL20, which can promote mucosal Th17 immune responses and neutrophil recruitment. Prevotella-mediated mucosal inflammation leads to systemic dissemination of inflammatory mediators, bacteria and bacterial products, which in turn may affect systemic disease outcomes. Studies in mice support a causal role of Prevotella as colonization experiments promote clinical and inflammatory features of human disease. When compared with strict commensal bacteria, Prevotella exhibit increased inflammatory properties, as demonstrated by augmented release of inflammatory mediators from immune cells and various stromal cells. These findings indicate that some Prevotella strains may be clinically important pathobionts that can participate in human disease by promoting chronic inflammation. © 2017 John Wiley & Sons Ltd
Pinchart P.,Metropolitan University of Technology
ARQ | Year: 2017
The explicit use of references in Steven Holl’s oeuvre allows for the review of his design process, interests and influences. By connecting these to disciplinary imagery, the text dives in those references – both internal and external to architecture – to explain how they define, in Holl’s work, a notion of form and program that is something much more complex than just fulfilling specific requirements of use or function. © 2017, Pontificia Universidad Catolica de Chile. All rights reserved.
Cortes-Arriagada D.,Metropolitan University of Technology |
Villegas-Escobar N.,University of Santiago de Chile
Applied Surface Science | Year: 2017
Density functional theory calculations were carried out to study the adsorption and sensing properties of Fe-doped graphene nanosheets (FeG) toward nitrogen oxides (NO, NO2, and N2O). The results indicated the adsorption of nitrogen oxides is significantly increased onto FeG compared to pristine graphene, reaching adsorption energies of 1.1–2.2 eV, even with a high stability at room temperature. As a result of the larger charge transfer and strong chemical binding, the bandgap of the adsorbent-adsorbate systems is increased in up to 0.5 eV with respect to the free FeG, indicating that FeG is highly sensitive to nitrogen oxides. It was also evidenced the adsorption and sensing properties remain even in the presence of O2 currents for N2O, where a co-adsorption mechanism was analyzed. Besides, NO2 is capable to induce the largest magnetization of FeG. Finally, positive electric fields of at least 0.04 a.u. decrease the stability of the adsorbent-adsorbate interactions, inducing the desorption process. Therefore, FeG emerges as a promising low-dimensional material with excellent adsorption and sensing properties to be applied in solid state sensors of nitrogen oxides, where electric fields can be used as a strategy for the FeG reactivation in repetitive sensing applications. © 2017 Elsevier B.V.
Cortes-Arriagada D.,Metropolitan University of Technology
International Journal of Quantum Chemistry | Year: 2017
Density functional theory calculations were implemented to expand the knowledge about graphyne and its interaction with polycyclic aromatic hydrocarbons (PAHs). Due to the porous character of graphyne, the adsorption strength of PAHs onto graphyne surfaces is expected to be lower with respect to graphene (a perfect π-extended system). However, there are not quantitative evidences for this assumption. This work shows that the adsorption strength of adsorbed PAHs onto γ-graphyne nanosheets (GY) is weakened in 12 − 23% with respect to the adsorption onto graphene, with a decrease of 10 − 20% in the dispersive interactions. The adsorption energies (in eV) of the GY–PAH systems can be straightforward obtained as Eads/eV≈0.033NH + 0.031NC, where NH and NC is the number of H and C atoms in the aromatic molecule, respectively. This equation predicts the binding energy of graphene–graphyne bilayers with a value of ∼31 meV/atom. Analysis of the electronic properties shows that PAHs behaves as n-dopants for GY, introducing electrons in GY and also reducing its bandgap in up to ∼0.5 eV. Strong acceptor or donor substituted PAHs decrease the bandgap of γ-graphyne in up to ∼0.8 eV, with changes in its valence or conduction band, depending on the chemical nature of the adsorbate. Finally, these data will serve for future studies related to the bandgap engineering of graphyne surfaces by nonaggressive molecular doping, and for the development of graphyne-based materials with potential applications in the removal of persistent aromatic pollutants. © 2017 Wiley Periodicals, Inc.
Chavarria J.,Polytechnic University of Catalonia |
Biel D.,Polytechnic University of Catalonia |
Guinjoan F.,Polytechnic University of Catalonia |
Meza C.,Costa Rica Institute of Technology |
Negroni J.J.,Metropolitan University of Technology
IEEE Transactions on Industrial Electronics | Year: 2013
This paper presents an energy-balance control strategy for a cascaded single-phase grid-connected H-bridge multilevel inverter linking n independent photovoltaic (PV) arrays to the grid. The control scheme is based on an energy-sampled data model of the PV system and enables the design of a voltage loop linear discrete controller for each array, ensuring the stability of the system for the whole range of PV array operating conditions. The control design is adapted to phase-shifted and level-shifted carrier pulsewidth modulations to share the control action among the cascade-connected bridges in order to concurrently synthesize a multilevel waveform and to keep each of the PV arrays at its maximum power operating point. Experimental results carried out on a seven-level inverter are included to validate the proposed approach. © 2012 IEEE.
Mosquera E.,University of Chile |
Del Pozo I.,Metropolitan University of Technology |
Morel M.,University of Chile
Journal of Solid State Chemistry | Year: 2013
The structure and the optical band gap of CdO-ZnO nanocomposites were studied. Characterization using X-ray diffraction (XRD), transmission electron microscopy (TEM) and diffuse reflectance spectroscopy (DRS) analysis confirms that CdO phase is present in the nanocomposites. TEM analysis confirms the formation of spheroidal nanoparticles and nanorods. The particle size was calculated from Debey-Sherrer′s formula and corroborated by TEM images. FTIR spectroscopy shows residual organic materials (aromatic/Olefinic carbon) from nanocomposites surface. CdO content was modified in the nanocomposites in function of polyvinylalcohol (PVA) added. The optical band gap is found to be red shift from 3.21 eV to 3.11 eV with the increase of CdO content. Photoluminescence (PL) measurements reveal the existence of defects in the synthesized CdO-ZnO nanocomposites. © 2013 Elsevier Inc.
Poblete-Castro I.,Helmholtz Center for Infection Research |
Poblete-Castro I.,Metropolitan University of Technology |
Binger D.,Helmholtz Center for Infection Research |
Rodrigues A.,TU Braunschweig |
And 4 more authors.
Metabolic Engineering | Year: 2013
Here, we present systems metabolic engineering driven by in-silico modeling to tailor Pseudomonas putida for synthesis of medium chain length PHAs on glucose. Using physiological properties of the parent wild type as constraints, elementary flux mode analysis of a large-scale model of the metabolism of P. putida was used to predict genetic targets for strain engineering. Among a set of priority ranked targets, glucose dehydrogenase (encoded by gcd) was predicted as most promising deletion target. The mutant P. putida Δ. gcd, generated on basis of the computational design, exhibited 100% increased PHA accumulation as compared to the parent wild type, maintained a high specific growth rate and exhibited an almost unaffected gene expression profile, which excluded detrimental side effects of the modification. A second mutant strain, P. putida Δ. pgl, that lacked 6-phosphogluconolactonase, exhibited a substantially decreased PHA synthesis, as was also predicted by the model. The production potential of P. putida Δ. gcd was assessed in batch bioreactors. The novel strain showed an increase of the PHA yield (+80%), the PHA titer (+100%) and cellular PHA content (+50%) and revealed almost unaffected growth and diminished by-product formation. It was thus found superior in all relevant criteria towards industrial production. Beyond the contribution to more efficient PHA production processes at reduced costs that might replace petrochemical plastics in the future, the study illustrates the power of computational prediction to tailor microbial strains for enhanced biosynthesis of added-value compounds. © 2012 Elsevier Inc.
Hansen M.V.,Copenhagen University |
Danielsen A.K.,Metropolitan University of Technology |
Hageman I.,Copenhagen University |
Rosenberg J.,Copenhagen University |
Gogenur I.,Copenhagen University
European Neuropsychopharmacology | Year: 2014
Circadian- and sleep disturbances may be central for understanding the pathophysiology and treatment of depression. The effect of melatonin on depression/depressive symptoms has been investigated previously. This systematic review assesses the current evidence of a therapeutic- and prophylactic effect of melatonin in adult patients against depression or depressive symptoms. A search was performed in The Cochrane Library, PubMed, EMBASE and PsycINFO for published trials on November 14th 2013. Inclusion criteria were English language, RCTs or crossover trials. Our outcome was measurement of depression/depressive symptoms with a validated clinician-administered or self-rating questionnaire. PRISMA recommendations were followed and the Cochrane risk-of-bias tool used. Ten studies in 486 patients were included in the final qualitative synthesis and four studies, 148 patients, were included in two meta-analyses. Melatonin doses varied from 0.5-6. mg daily and the length of follow-up varied from 2 weeks to 3.5 years. Three studies were done on patients without depression at inclusion, two studies in patients with depression and five studies included a mixture. Six studies showed an improvement in depression scores in both the melatonin and placebo groups but there was no significant difference. One study showed a significant prophylactic effect and another found a significant treatment effect on depression with melatonin compared to placebo. The two meta-analyses did not show any significant effect of melatonin. No serious adverse events were reported. Although some studies were positive, there was no clear evidence of a therapeutic- or prophylactic effect of melatonin against depression or depressive symptoms. © 2014 Elsevier B.V. and ECNP.
Johnsen H.,Metropolitan University of Technology
Women and Birth | Year: 2015
Background: Post bureaucracy is increasingly shaping how health care professionals work. Within hospital settings, post bureaucracy is frequently connected to loss of professional autonomy and protocol-based care. However, this development also affects relationships between care providers and care receivers. Question: To explore experiences of post bureaucratic hospital reforms and their impact on care provision. Method: Data builds on nine mini group interviews with midwives (n = three), nurses (n = three) and physiotherapists (n = three), in all thirty participants. Data was analysed using existing theories of professionalism and post bureaucracy. Findings: Two overarching themes were identified: 'Time, tasks and institutional duties' which referred to transformations in care practices, increased use of screening procedures, efficiency requirements and matching linear time to the psychosocial needs of patients. 'Managerial control of work' which described rising administrative demands, engaging in protective measures, younger professionals pressured by documentation obligations and fear of disciplinary procedures. Conclusion: The institutional context appears to play a key role shaping care practices. Although midwives, nurses and physiotherapists share similar experiences of post bureaucratic hospital reforms, changes in care provision can impact these professions in different ways. As a discipline, midwifery is founded on relationships between women and midwives. Standardised clinical care, performativity demands, litigation risks and rising administrative obligations are liable to challenge the provision of woman centred care. These changes may also result in increased inequity in maternity care by affecting some groups of women more than others. © 2015 Australian College of Midwives.