Time filter

Source Type

Vendemiato A.V.R.,Methodist University of Piracicaba | von Nowakonski A.,University of Campinas | Marson F.A.L.,University of Campinas | Levy C.E.,University of Campinas
BMC Infectious Diseases | Year: 2015

Microbiological characteristics of sepsis and antimicrobial resistance are well studied, although in State University of Campinas, no data has been published yet. Methods: The main agents related to sepsis and antimicrobial resistance were analyzed. The blood culture records requested from 4,793 hospitalized patients were analyzed. The samples were processed using the Bact/Alert® system for agent identification and antimicrobial susceptibility. Results: A total of 1,017 patients met the inclusion criteria for a sepsis diagnosis, with 2,309 samples tested (2.27 samples/patient). There were 489 positive samples (21% positive) isolated from 337 patients (33.13%), but more rigorous criteria excluding potential contaminants resulted in analysis being restricted to 266 patients (315 agents). The prevalent microorganisms were coagulase negative (CNS) (15.87%), (13.0%), (11.7%), (9.8%), (9.5%), (9.2%), (5.7%) and (5.1%). Examining antimicrobial resistance in the agents revealed that 51% of the isolates were methicillin-resistant (MRSA) and 80% of the CNS isolates were oxacillin-resistant. For, the ideal profile drugs were ampicillin sulbactam and piperacillin/tazobactam, and for, they were piperacillin/tazobactam and ceftazidime. Enterobacteria showed on average 32.5% and 35.7% resistance to beta-lactams and ciprofloxacin, respectively. When all Gram-negative bacteria were considered, the resistance to beta-lactams rose to 40.5%, and the resistance to ciprofloxacin rose to 42.3%. Conclusions: Eighty percent of the agents identified in blood cultures from patients with sepsis belonged to a group of eight different agents For empirical treatment, carbapenems and vancomycin unfortunately still remain the best therapeutic choice, except for and, for which piperacillin/tazobactan is the best option. © Vendemiato et al. Source

Alburquerque-Sendin F.,University of Salamanca | Camargo P.R.,Federal University of Sao Carlos | Camargo P.R.,Methodist University of Piracicaba | Vieira A.,Federal University of Sao Carlos | Salvini T.F.,Federal University of Sao Carlos
Clinical Journal of Pain | Year: 2013

Objectives: To identify the presence of myofascial trigger points (TrPs) and pressure pain threshold (PPT) levels in the shoulder muscles of both involved and uninvolved sides in patients with unilateral shoulder impingement syndrome (SIS). Methods: Twenty-seven patients with SIS and 20 matched control patients participated in this study. TrPs of 10 shoulder muscles and 8 PPTs, including tibialis anterior PPT, were assessed. Results: SIS group showed a greater number of TrPs (t=-2.697; P=0.010) than the control group. The muscles of the uninvolved side of the SIS group also presented some active TrPs. PPTs showed small differences between involved and uninvolved sides of patients with SIS and higher differences between both sides of the SIS group and dominant side of controls although with significant difference only in the supraspinatus PPT (F=3.239; P=0.045). The muscle PPTs of the patients presenting TrPs in each muscle of the involved side were lower than the PPTs of the patients without TrPs in the same muscle for both involved and uninvolved sides with few significant differences. Discussion: The high number of TrPs in the involved side of patients with SIS suggests the presence of peripheral sensitization. The results reject the presence of central alterations. Finally, the patients with unilateral SIS may present bilateral deficits related to myofascial pain. © 2013 by Lippincott Williams & Wilkins. Source

Nascimben Matheus C.,Methodist University of Piracicaba | Caldeira De Oliveira Guirro E.,University of Sao Paulo
Breast Cancer Research and Treatment | Year: 2011

The aim of this study was to evaluate the arterial and venous blood flow in women who underwent upper limb axillary dissection surgery for the treatment of breast cancer. Sixty women were divided into two groups: group 1 (G1)-30 women who underwent breast surgery with axillary dissection level II or III (55.6 ± 8.6 years); group 2 (G2)-control, 30 women with no breast cancer (57.4 ± 7.0 years). Blood flow profile was evaluated by a continuous wave ultrasound Doppler device (Nicolet Vascular Versalab SE ®) with an 8 MHz probe. Axillary, brachial arteries and veins, arm circumference, volumes, and the ankle-brachial index (ABI) were examined. Wilcoxon test and Mann-Whitney tests were applied to analyze blood flow velocity intra-group and between G1 and G2, respectively. The G1 results showed no lymphedema and no peripheral arterial disease (ABI > 0.9). Moreover, the mean blood flow velocity of the vessels ipsilateral to the surgery was significantly higher than the contralateral ones for all vessels examined (P < 0.05). The mean velocity of blood flow of the vessels contralateral to surgery was significantly higher than the axillary artery in G2 (P < 0.05). It can be concluded that women who underwent axillary dissection due to breast cancer showed probable stenosis in the arterial and venous axillary and brachial vessels of the upper limb ipsilateral to the surgery, confirmed by the increase of blood flow velocity, and such obstruction might affect the limb contralateral to the operation site. © 2011 Springer Science+Business Media, LLC. Source

Cardoso G.A.,University of Sao Paulo | Salgado J.M.,University of Sao Paulo | Cesar M.D.C.,Methodist University of Piracicaba | Donado-Pestana C.M.,University of Sao Paulo
Journal of Medicinal Food | Year: 2013

Green tea has been shown to have thermogenic and antiobesity properties. Therefore, it is important to investigate its effect on weight loss in humans, especially in women. We investigated the effects of green tea consumption combined with resistance training on the body composition and the resting metabolic rate (RMR) in women who were overweight or obese (grade I). After 4 weeks on an adaptive diet, 36 women were divided into four groups (group 1 green tea; group 2 placebo; group 3 green tea plus resistance training; group 4 placebo plus resistance training). The study was double-blinded and placebo-controlled. The RMR and body composition were ascertained for each volunteer, blood tests were performed, and subjects in groups 3 and 4 were tested for their one repetition maximum. Each subject followed the protocol and continued the diet for eight additional weeks, and periodic evaluations were administered. The mean RMR of group 1 decreased significantly and was accompanied by weight loss, maintenance of lean body mass, and decreases in both waist circumference and body mass index. Group 2 showed no variations in anthropometric or blood variables and significantly decreased their mean RMR. Group 3 showed significant increases in RMR, lean body mass, and muscle strength, and significant decreases in body fat, triglycerides, and waist circumference as compared to group 4. Green tea combined with resistance training its potential is increased with decreasing body fat, waist circumference, and triacylglyceride levels and by increasing lean body mass and muscle strength. © Copyright 2012, Mary Ann Liebert, Inc. and Korean Society of Food Science and Nutrition 2012. Source

Lima C.R.C.,Methodist University of Piracicaba | Cinca N.,University of Barcelona | Guilemany J.M.,University of Barcelona
Ceramics International | Year: 2012

The performance of an intermediate Cr 3C 2 ceramic layer applied by PVD between the bond coat and the ceramic top coat in a TBC system was evaluated. The thickness of the transitional layer was kept around 1-2 μm. Two substrate materials and two distinct bond coats were combined in the tests. High Velocity Oxygen Fuel (HVOF) and Atmospheric Plasma Spraying (APS) were used respectively for bond coat and top coat deposition. Isothermal oxidation tests were performed at 1000 °C in static air atmosphere. Thermal grown oxide (TGO) was measured and correlated to the exposition times. Results are discussed in terms of the TGO growth rate and changes in residual stresses. The results suggest an improvement in the oxidation resistance of the bond coat because of the presence of the intermediate layer. © 2012 Elsevier Ltd and Techna Group S.r.l. Source

Discover hidden collaborations