Okazaki, Japan
Okazaki, Japan

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Patent
Nagoya University and Menicon Co. | Date: 2017-05-03

The present invention provides a bone formation promoter having high biological safety and capable of promoting bone formation. The bone formation promoter of the present invention includes a self-assembling peptide capable of forming a -sheet structure in an aqueous solution having a neutral pH; and a bone chip. A sum of charges of amino acid residues constituting the self-assembling peptide at pH 7.0 is unequal to 0.


Patent
Menicon Co. and Osaka University | Date: 2017-05-17

It is an object of the present invention to provide a visibility-ensuring material which is capable of ensuring a surgical field for a predetermined time period, which does not inhibit the transmission of light, and which is capable of ensuring the visibility with which even delicate operations can be satisfactorily performed. A visibility-ensuring material of the present invention includes a gel-like viscoelastic body and has a storage elastic modulus during use of from 40 Pa to 700 Pa. A discharge device for a visibility-ensuring material of the present invention includes: a syringe; and at least one kind selected from the group consisting of a mesh filter, a needle, and an application nozzle.


Patent
Menicon Co. | Date: 2017-05-24

The purpose of the present invention is to provide novel contact lens manufacturing method and contact lens capable of giving a lens inner surface shape reflecting a cornea shape of a contact lens wearer more easily than before with sufficient accuracy to reflect the cornea shape, thereby improving comfort during use. By using statistical information on a corneal surface shape obtained from a population of target eyes having a feature to be treated, a fitting for a rotationally-symmetric shape is performed based on a definitional equation using a radius of curvature (R) and a conic constant (C.C.) while a fitting for a rotationally-asymmetric shape is performed based on a definitional equation using a Zernike function. A shape of a lens rear surface (20) corresponding to the corneal surface shape specified by these definitional equations is adopted for a rear surface of a peripheral area of a contact lens (10).


A method for manufacturing a diffractive multi-focal ophthalmic lens capable of generating at least three focal points in an optical axis direction using a diffractive structure comprising a plurality of zones in a concentric circle form. A composite profile is generated by overlapping at least two starting profiles comprising a plurality of zones in a concentric circle form, and an adjusted profile is generated in which at least one of phase and amplitude is adjusted by employing a zone of the composite profile as a subject in order to set an intensity distribution in the optical axis direction and determine optical characteristics, to manufacture the diffractive multi-focal ophthalmic lens for which the adjusted profile is provided in at least a portion of the diffractive structure.


A diffractive multi-focal lens having a diffractive structure comprising a plurality of concentric circular zones, wherein: at least a portion of the diffractive structure is provided with an overlapping region in which at least two zone profiles overlap in the same region; in the overlapping region, at least a portion of a first zone profile has a zone pitch represented by a prescribed equation, and at least a portion of a second zone profile has a zone pitch represented by another prescribed equation; and an addition power P_(1) given by the first zone profile and an addition power P_(2) given by the second zone profile are determined by a prescribed relational expression, in which a and b are mutually different real numbers, and a value of a/b cannot be expressed by a natural number X or by 1/X.


Patent
Menicon Co. and Shin - Etsu Chemical Co. | Date: 2016-06-02

A polysiloxane-based macromonomer for an ophthalmic lens, which exhibits excellent compatibility with respect to a hydrophilic component such as a hydrophilic monomer. The polysiloxane-based macromonomer has at least one polymerizable group, a polysiloxane chain having a siloxane unit as a repeating unit, a polyoxyethylene chain in which a number of repetition of an oxyethylene group is two or more, and a polyoxyalkylene chain having an oxyalkylene group other than the oxyethylene group as a repeating unit, wherein an HLB value calculated according to a formula: [HLB value]=E/5 is within a range from 0.7 to 6.0, wherein E represents a weight fraction (wt %) of the oxyethylene group in a molecule of the polyxiloxane-based macromonomer.


Patent
Menicon Co. and Shin - Etsu Chemical Co. | Date: 2016-10-26

A polysiloxane-based macromonomer for an ophthalmic lens, which exhibits excellent compatibility with respect to a hydrophilic component such as a hydrophilic monomer. The polysiloxane-based macromonomer has at least one polymerizable group, a polysiloxane chain having a siloxane unit as a repeating unit, a polyoxyethylene chain in which a number of repetition of an oxyethylene group is two or more, and a polyoxyalkylene chain having an oxyalkylene group other than the oxyethylene group as a repeating unit, wherein an HLB value calculated according to a formula: [HLB value] = E/5 is within a range from 0.7 to 6.0, wherein E represents a weight fraction (wt%) of the oxyethylene group in a molecule of the polyxiloxane-based macromonomer.


A designing method of a contact lens for myopia progression suppression including: providing a tonic accommodation relaxation region in which an additional power whose maximum value is from +0.25 to +0.75 diopters is set with respect to a correction power that is required for realizing a proper correction, the additional power being capable of relaxing a tonic accommodation without improving an aberration off an optical axis and an accommodation lag on the optical axis; and providing a proper correction region in which the additional power is not set at least on an optical center.


Patent
Menicon Co. | Date: 2016-06-09

An ophthalmic lens which gives excellent wearing comfort required for its use as a contact lens, and which has sufficiently high flexibility and an adequate degree of deformation recovery property required for its use as an intraocular lens. The ophthalmic lens is formed of a polymer having a youngs modulus of 0.3-1.0 MPa and a stress relaxation rate of 10-20%.


Patent
Menicon Co. | Date: 2016-10-26

An ophthalmic lens which gives excellent wearing comfort required for its use as a contact lens, and which has sufficiently high flexibility and an adequate degree of deformation recovery property required for its use as an intraocular lens. The ophthalmic lens is formed of a polymer having a youngs modulus of 0.3-1.OMPa and a stress relaxation rate of 10-20%.

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