Menicon Co.

Okazaki, Japan

Menicon Co.

Okazaki, Japan
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Patent
Menicon Co. and Osaka University | Date: 2017-05-17

It is an object of the present invention to provide a visibility-ensuring material which is capable of ensuring a surgical field for a predetermined time period, which does not inhibit the transmission of light, and which is capable of ensuring the visibility with which even delicate operations can be satisfactorily performed. A visibility-ensuring material of the present invention includes a gel-like viscoelastic body and has a storage elastic modulus during use of from 40 Pa to 700 Pa. A discharge device for a visibility-ensuring material of the present invention includes: a syringe; and at least one kind selected from the group consisting of a mesh filter, a needle, and an application nozzle.


The present invention describes the identification of two single nucleotide polymoiphisms (SNPs) within the SRBD1 gene, which are associated with canine glaucoma. The invention relates to these SNP markers and the use thereof for the diagnosis of glaucoma across and within dog breeds. The invention also relates to a method of diagnosing glaucoma in dogs or of identifying dogs at risk of developing glaucoma, which comprises detecting the identity, presence or absence of at least one of the described SNPs. Reagents and kits useful for carrying out the diagnosis method are also provided.


A decentered type contact lens including: an optical zone provided in a center part of the contact lens; a peripheral zone provided on an outer circumference of the optical zone; an optical center of the optical zone being set to deviate from a lens geometric center; and a circumferential direction alignment mechanism for setting a lens circumferential direction position in a worn state, the contact lens being characterized in that: a center-of-gravity deviation in relation to the lens geometric center is set for the peripheral zone, and a center-of-gravity position shift accompanying deviation of the optical center of the optical zone in relation to the lens geometric center is corrected by offset using the center-of-gravity deviation of the peripheral zone.


Patent
Menicon Co. and Dainichiseika Color & Chemicals Manufacturing Co. | Date: 2017-01-25

Provided is an ophthalmic lens, from which the elution of a coloring agent can be prevented effectively even when the ophthalmic lens is produced by polymerizing a polymerizable composition containing the coloring agent or when the ophthalmic lens is produced by printing an ink composition containing a coloring agent on a lens precursor by a know printing technique such as an inkjet printing method to allow the coloring agent to penetrate into the lens precursor. The ophthalmic lens is produced using a non-polymerizable compound represented by a specific structural formula as a coloring agent.


Patent
Menicon Co. | Date: 2017-05-24

The purpose of the present invention is to provide novel contact lens manufacturing method and contact lens capable of giving a lens inner surface shape reflecting a cornea shape of a contact lens wearer more easily than before with sufficient accuracy to reflect the cornea shape, thereby improving comfort during use. By using statistical information on a corneal surface shape obtained from a population of target eyes having a feature to be treated, a fitting for a rotationally-symmetric shape is performed based on a definitional equation using a radius of curvature (R) and a conic constant (C.C.) while a fitting for a rotationally-asymmetric shape is performed based on a definitional equation using a Zernike function. A shape of a lens rear surface (20) corresponding to the corneal surface shape specified by these definitional equations is adopted for a rear surface of a peripheral area of a contact lens (10).


A method for manufacturing a diffractive multi-focal ophthalmic lens capable of generating at least three focal points in an optical axis direction using a diffractive structure comprising a plurality of zones in a concentric circle form. A composite profile is generated by overlapping at least two starting profiles comprising a plurality of zones in a concentric circle form, and an adjusted profile is generated in which at least one of phase and amplitude is adjusted by employing a zone of the composite profile as a subject in order to set an intensity distribution in the optical axis direction and determine optical characteristics, to manufacture the diffractive multi-focal ophthalmic lens for which the adjusted profile is provided in at least a portion of the diffractive structure.


A diffractive multi-focal lens having a diffractive structure comprising a plurality of concentric circular zones, wherein: at least a portion of the diffractive structure is provided with an overlapping region in which at least two zone profiles overlap in the same region; in the overlapping region, at least a portion of a first zone profile has a zone pitch represented by a prescribed equation, and at least a portion of a second zone profile has a zone pitch represented by another prescribed equation; and an addition power P_(1) given by the first zone profile and an addition power P_(2) given by the second zone profile are determined by a prescribed relational expression, in which a and b are mutually different real numbers, and a value of a/b cannot be expressed by a natural number X or by 1/X.


Patent
Nagoya University and Menicon Co. | Date: 2017-05-03

The present invention provides a bone formation promoter having high biological safety and capable of promoting bone formation. The bone formation promoter of the present invention includes a self-assembling peptide capable of forming a -sheet structure in an aqueous solution having a neutral pH; and a bone chip. A sum of charges of amino acid residues constituting the self-assembling peptide at pH 7.0 is unequal to 0.


Patent
Menicon Co. and Nagoya Institute of Technology | Date: 2017-04-12

A contact lens is provided as a hydrate of a copolymer of at least three components including (I) a both terminal-polymerizable silicone oligomer component that forms a hydrophobic region (A) in the copolymer, (II) a hydrophilic component that forms a hydrophilic region (C) in the copolymer, and (III) a hydrophobic monomer component having a molecular weight of at most 700 that forms the hydrophilic region (C) together with the component (II) and also contributes to form an intermediate region (B) which does not solvate with a hydrophilic solvent between said hydrophobic region (A) and hydrophilic region (C), wherein the intermediate region (B) shows a volume rate of 5 to 40% with respect to the region (A) in the copolymer, and the contact lens is transparent and free from bubbles therein. The contact lens is not only transparent but also is characterized by a combination of a high oxygen permeability, and a balance between softness and mechanical properties. The lens is produced through a process including steps of stirring a material liquid comprising at least three components of the above-mentioned components (I), (II) and (III) under a stirring power of 5 - 10000 W/m^(3) per unit volume of the material liquid for at least 10 minutes, and the injecting the stirred material liquid into a lens mold to polymerize the material liquid.


Patent
Menicon Co. and Nagoya Institute of Technology | Date: 2017-04-12

A contact lens is provided as a hydrate of a copolymer of at least three components including (I) a both terminal-polymerizable silicone oligomer exhibiting a viscosity of at least 200 mPa s at room temperature, (II) a hydrophilic monomer component having an ethylenically unsaturated group, and (III) a hydrophobic monomer component having a molecular weight of at most 700, wherein the contact lens exhibits an elastic-modulus ratio determined as a ratio of a rupture elastic modulus to an initial elastic modulus in a range of 0.8 - 1.2. The contact lens is not only transparent but also is characterized by a combination of a high oxygen permeability and a balance between softness and mechanical properties. The lens is produced through a process including steps of stirring a material liquid comprising at least three components of the above-mentioned components (I), (II) and (III) under a stirring power of 5 - 10000 W/m^(3) per unit volume of the material liquid for at least 10 minutes, and then injecting the stirred material liquid into a lens mold to polymerize the material liquid.

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