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Uberlândia, Brazil

Fonseca L.A.,Universitario Vila Velha | Ton A.,Medicos Veterinarios autonomos | Costa F.S.,University of Pernambuco | Alves A.,Universitario Vila Velha | And 2 more authors.
Ciencia Animal Brasileira | Year: 2012

The nefrotoxicity of prednisone in cats was evaluated, using an immunesupressor dose (5 mg/kg/day), by establishing blood count, serum biochemistry (urea and creatinine) and urinary (GGT, protein and creatinine) parameters and urinalysis. Eight cats were used. The animals were of undefinied breed, adults and with average weight of 3 kg. They were housed in four cubicles and fed with two measures of commercial ration per day and water ad libitum during an adaptation period of seven days. The trial design was entirely random, being rejected any specific criterion of inclusion in this study besides the absence of any previous kidney damage. Animals received 5 mg/kg prednisone, orally, every 24 hours for a period of 14 days. The samples were collected in two different times, with the animals resting before prednisone administration (M1), and 14 days after the administration (M2). Significant differences were found in some hematological and biochemical parameters as well as in urinalysis. It was concluded that the prednisone (5 mg/kg/day), during a period of 14 days, is potentially nephrotoxic and the determination of the urinary GGT activity was proven to be precisely sensitive to early proximal tubular injury.


Martins C.F.G.,Medicos Veterinarios autonomos | De Oliveira P.M.,Federal University of Uberlandia | Nasciutti N.R.,Federal University of Uberlandia | De Morais Barbosa V.,Federal University of Uberlandia | And 5 more authors.
Semina:Ciencias Agrarias | Year: 2013

The objective of this study was to evaluate the gynecological examination and endometrial cytology in Holstein cows with more than three repetitions of estrus. The experiment was conducted in six commercial dairy herds both with similar reproductive and sanitary managements and assisted by veterinarians. It was included only Holstein cows up to five calving and more than three consecutive repetitions of estrus. Seventy-seven cows were identified and carried gynecological examination and endometrial cytology. The reproductive causes found in this study, subject to involuntary culling, were: clinical endometritis.with purulent vaginal discharge and more than 3% neutrophils (7.79%), clinical endometritis with purulent vaginal discharge and less than 3% neutrophils (2.6%), subclinical endometritis (10.4%), urovagina (1.3%) and 77.9% cows with unknown causes and they were not associated with reproductive disorders evaluated. It was concluded: A) the rate of cows without diagnosis is very high and it interferes directly to the reproductive performance; b) the proposed examination diagnosed 22.1% of clinical disorders that might be prevented or treated and thus decreasing the involuntary culling.


Ferreira J.L.,Federal University of Tocantins | Lopes F.B.,University of Wisconsin - Madison | De Sousa Pereira L.,Medicos Veterinarios autonomos | Nepomuceno L.L.,Medicos Veterinarios autonomos | And 3 more authors.
Semina:Ciencias Agrarias | Year: 2015

Random regression models are currently used in genetic evaluation of beef cattle, because they allow changes in the mean and variance of the trait over time as well as estimation of (co) variances between any points along the growth curve. This study aimed to estimate (co)variances and genetic parameters for growth traits of Nelore cattle by random regression using models with heterogeneous and homogeneous residual variance. We utilized 23,278 weight records from birth to 550 days of age, from animals born between 1993 and 2010. The best-ftting model considered direct genetic, maternal genetic, permanent environmental animal and maternal permanent environmental effects, adjusted by fourth, third, sixth and fourth order polynomials, respectively. Heritability estimates for direct genetic effect increased from 120 to 450 days of age and then decreased at 550 days of age. Values at 120, 210, 365, 450 and 550 were 0.23, 0.23, 0.38, 0.52 and 0.43, respectively. Estimates of maternal heritability were low for all ages analyzed, ranging from 0.01 to 0.08. The genetic correlations were moderate to high, even at age extremes.


Delfino J.L.,Medicos Veterinarios autonomos | De Morais Barbosa V.,Federal University of Uberlandia | Gondim C.C.,Federal University of Uberlandia | De Oliveira P.M.,Federal University of Uberlandia | And 5 more authors.
Semina:Ciencias Agrarias | Year: 2014

The serum biochemical values allow to establish reference used in metabolic and clinical evaluations of calves, reducing losses in cattle breeding. The aim of this study was to evaluate the influence of age on serum biochemical profile in Senepol calves, at the first 120 days of age. The experiment was conducted in the city of Uberlândia, Minas Gerais, Brazil, in four periods after birth (0-15, 30, 60 and 120 days of age). Blood samples were obtained by jugular venipuncture for determination of serum total protein, albumin, globulin, triglycerides, cholesterol, AST, GGT, FA, calcium, phosphorus, magnesium, creatinine and urea. Cholesterol remained at minimum reference values or below throughout the experiment. Animals at 30 days showed the lowest values of protein concentrations, minerals and triglycerides that normalized up to 60 days of life, except to albumin that slower recovery was showed. Our data showed that the serum biochemical profile in Senepol is influenced by age up to 120 days of age; moreover there are differences with other breeds.


Reginatto R.C.,Medicos Veterinarios autonomos | Frehse M.S.,State University Londrina | Tanaka N.M.,University of Northern Parana | Favero V.,Medicos Veterinarios autonomos | And 3 more authors.
Semina:Ciencias Agrarias | Year: 2011

The shunt portosystemic or portosystemic deviation (PSD) are unique or multiples vascular communications between the systemic circulaton and the portal circulation, that permit blood flow reaches the circulatory system without first passing trhought the hepatic metabolization. May be acquired or congenital and can also be classified as intrahepatic located within the liver or extrahepatic located outside the liver parenquima. The acquired form is usually associated with intra-hepatic disorders. They usually suggest tortuous vessels that communicate with the caudal vena cava in the region of the left kidney. The congenital form is associated with genetic lineage and one of the most affected is Maltese breed. This case report describes the diagnostis and treatment of a eight year-old female Maltese dog presenting extrahepatic Portosystemic Shunt. The patient showed signs of hepatic encephalopathy, such as restlessnees, weakness, deambulation, head tremor and impaired visual. Complementary exam demonstrated: postprandial glicemia near the lower limit of reference, alkaline phosphatase (ALP) and alanine aminotransferase (ALT) increased and hipoalbuminemia. Ultrasonography revealed the presence of vesical calculus and bilateral kidney, liver decreases and increased echogenicity, gallbladder with anechoic content and high cellularity may suggest liver/colangiohepatopatia and extrahepatic DPS was detected. The use of Doppler assisted in identifying the location of the bypass communication and the turbulence detecting the extrahepatic DPS. Protein-restricted diet and antibiotic therapy with amoxicillin achieved good results. The clinical treatment was decided make only the clinical and maintain the quality of life of the patient. © Pleiades Publishing, Ltd., 2011.

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