Medicinski fakultet Sveucilista u Rijeci

Rijeka, Croatia

Medicinski fakultet Sveucilista u Rijeci

Rijeka, Croatia

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Jurica K.,Ministarstvo unutarnjih poslova | Ursulin-Trstenjak N.,Veleuciliste u Varazdinu | Vukic Lusic D.,Nastavni zavod za javno zdravstvo | Lusic D.,Medicinski fakultet Sveucilista u Rijeci | Smit Z.,Zavod za javno zdravstvo Dr. Andrija Stampar
Arhiv za Higijenu Rada i Toksikologiju | Year: 2013

Phthalates are phthalic acid and aliphatic alcohol esters used as additives to plastic in order to improve its softness, flexibility, and elongation. Phthalates are highly mobile and migrate easily from plastic products into the environment due to their physical and chemical properties. This study briefly describes the characteristics and distribution of phthalates in the environment, their toxic effects on human health, the legislation regarding the maximum allowed concentration of phthalates in drinking water and products intended for infants, as well as the tolerable daily intake. Special attention is given to the methods of determining phthalates and their levels in alcoholic beverages, with an overview of phthalate occurrences and concentrations in plum brandy made in Croatia. A segment on denatured alcohol and illegally marketed alcohol is also included, as well as guidelines for the effective monitoring of the routes of human exposure to phthalates.

PubMed | Medicinski fakultet Sveucilista u Splitu, Klinicka bolnica Sveti Duh, Medicinski fakultet Sveucilista u Osijeku, Medicinski fakultet Sveucilista u Rijeci and 2 more.
Type: Guideline | Journal: Lijecnicki vjesnik | Year: 2014

Urothelial cancer is the most common bladder cancer. Hematuria is the most common presenting symptom in patients with bladder cancer. The most common diagnostics of bladder cancer is performed by transurethral resection of bladder after which pathohistological diagnosis is set. It is necessary to determine whether the cancer penetrated in muscle layer (muscle-invasive cancer) or not (muscle-noninvasive cancer). Decision on therapeutic modality depends on the clinical stage of disease and on prognostic and risk factors. For muscle non-invasive bladder cancer transurethral resection is preferred with or without intravesical instillation of Bacillus Calmette-Gurin (BCG). For invasive cancer the method of choice is radical cystectomy. Radiotherapy is used in radical and palliative purposes. Metastatic disease is most frequently treated by chemotherapy metotrexate/vinblastine/doxorubicine/cisplatin (MVAC) or gemcitabine/cisplatin (GC). The purpose of this article is to present clinical recommendations to set standards of procedures and criteria in diagnostics, treatment and follow up of patients with bladder cancer in the Republic of Croatia.

PubMed | Opca bolnica Varazdin, Klinilka bolnica Sv. Duh, Medicinski fakultet Sveucilista u Splitu, Medicinski fakultet Sveucilista u Osijeku and 3 more.
Type: Guideline | Journal: Lijecnicki vjesnik | Year: 2014

Prostate adenocarcinoma is the second most common solid neoplasm in male population in Croatia. It rarely causes symptoms unless it is advanced. The finding of PSA rise is the most common reason for diagnostic workout. Treatment plan is based on TNM classification, Gleason score and PSA. Clinically localized disease is successfully treated by radical prostatectomy or radiotherapy with or without hormonal therapy. Locally advanced disease is treated with radiotherapy and hormonal therapy. Metastatic disease can be controlled for many years by androgen deprivation. For castration resistant disease appropriate treatment is chemotherapy or secondary hormonal therapy. The following paper presents the clinical guidelines in order to standardize procedures and criteria for the diagnosis, management, management, treatment and monitoring of patients with prostate cancer in the Republic of Croatia.

Bucuk M.,Klinika za neurologiju | Sonnenschein I.,Klinika za neurologiju | Novak P.,Medicinski fakultet Sveucilista u Rijeci
Medicina Fluminensis | Year: 2014

Aim: To report a rare entity of flail-arm syndrome, a variant of amyotrophic lateral sclerosis.Case Report: We present a male patient at 68 years of age with proximal muscle atrophy of upper extremities and shoulders. Deep tendon reflexes in upper extremities were absent, while hyperactive in lower extremities. Plantar reflex was physiological on both sides. Fasciculations were visible in both arms. There were no signs of bulbar weakness. His condition was unchanged during 27 months after the onset of symptoms.Conclusion: The results of diagnostic procedures and clinical findings indicate the presence of flail-arm sindrome. © 2014, Croatian Medical Association and School of Medicine. All rights reserved.

Pin M.,Medicinski Fakultet Sveucilista u Rijeci | Stimac D.,Klinika za Intcrnu Medicinu
Lijecnicki Vjesnik | Year: 2015

Pancreatic cancer is an aggressive tumor with a very poor prognosis, lack of early diagnostic symptoms and highly resistant to therapy. Its incidence is approximately equal to the mortality rate. Even though in recent years progress has been made in defining the morphological and key genetic changes, it is still unclear which factors trigger its occurrence. Some risk factors are age, gender and race, genetic susceptibility, dietary factors, fever, chronic pancreatitis, diabetes and physical inactivity. Studies have shown that an increase in BMI consequently leads to an increased risk of malignancies, including pancreatic cancer. Research based on adipokines and their role in obesity and the occurrence of pancreatic cancer are the potential for a possible future therapeutic interventions.

PubMed | Medicinski fakultet Sveucilista u Osijeku, Medicinski fakultet Sveucilista u Splitu, Medicinski fakultet Sveucilista u Rijeci, University of Zagreb and KBC Sestre milosrdnicec
Type: Guideline | Journal: Lijecnicki vjesnik | Year: 2014

Testicular tumors are the most common solid tumors in men between 15 and 34 years of age. The worldwide incidence of these tumors has doubled in the past 40 years. Germ cell tumors comprise 95% of malignant tumors arising in the testes and they are classified either as seminoma or nonseminoma. Testicular cancers have a high cure rates even in disseminated stage of the disease. The chemotherapy mostly contributed to these results but surgery is an inevitable part of successful treatment. In a significant number of these patients treatment algorithms with minimum side effects are designed with the intention to maintain same cure rates as previously used, more aggressive therapy. The following text presents the clinical guidelines in order to standardize the procedures and criteria for diagnosis, management, treatment and follow-up of patients with testicular cancer in Republic of Croatia.

Rozmanic V.,Medicinski Fakultet Sveucilista u Rijeci
Paediatria Croatica, Supplement | Year: 2014

As in adults with asthma, comorbidities are present in children with asthma, particularly in those with problematic or uncontrolled asthma. Asthma in children is associated with comorbidities such as allergic rhinitis, food allergy, gastroesophageal reflux, dysfunctional breathing, vocal cord dysfunction, mental disorders and obesities. Better control of asthma in children can be achieved by active search of comorbidities and their treatment. The current medical knowledge about comorbidities of asthma in children is presented.

Giacometti J.,Odjel za biotehnologiju Sveucilista u Rijeci | Buretic-Tomljanovic A.,Medicinski fakultet Sveucilista u Rijeci
Medicina (Croatia) | Year: 2013

To explore the prevalence of dyslipidemia and to determine specific anthropometric and physiologic features and their correlation with nutritional and other lifestyle habits of the student population from University of Rijeka, Croatia. Patients and methods: 38 women and 15 men participated in the study. At first, they fullfilled the questionaire about their nutritional and lifestyle habits. Blood levels of the glucose, total cholesterol and triglicerides, systolic and diastolic blood pressure, puls values and several anthropometric values were measured thereafter using The Accutrend® Plus cardiovascular screening analyser, fully automatic wrist cuff blood pressure monitor, and digital personal balance. The results were compared between sexes. Results: The mean values of biochemical and physiologic characteristics were in the normal range in both sexes. Nutritional and other lifestyle habits did not significantly differ between men and women. Unregular consumption of the fruits and vegetables was correlated with higher blood glucose and total cholesterol level in men and women, respectively (P1=0.01 and P2<0.01). In women, several anthropometric variables, such as lower percentage of body water and higher percentage of body fat, were correlated with the periodical consumption of alcohol (P < 0.001). In men, consumption of alcohol was associated with higher diastolic blood pressure. Anthropometric, biochemical and physiologic features showed moderate intercorrelation in both sexes (P < 0.05). Conclusion: Dyslipidemia, higher level of blood glucose, total cholesterol and blood pressure, that are known predictors of cardiovascular disease in later life, were not found in our student sample. However, biochemical, physiologic and anthropometric characteristics of the population of youger adults showed significant correlations with bad nutritional habits and consumption of alcohol.

In addition to the basic biographical data on Dr. Antonio Felice Giacich (Lovran, 1813 - Rijeka, 1898), the article also describes the nineteenth-century medical environment in Rijeka which enabled him to make a distinguished professional career as a polyvalent practitioner and medical author, as seen from a respectable bibliography. Dr. Giacich earned his greatest merits in maritime medicine, and he could be regarded as its pioneer in the Habsburg Monarchy. After the International Congress in Paris in 1851, which was dedicated to maritime health issues, Dr. Giacich wrote the first maritime medical manual "Lezioni mediche per i naviganti" (Medical Lessons for Seafarers), later published in five editions.

Aim: To find public health rules in the oldest medieval statutes of the towns on the Croatian Adriatic coast. Methods: The original documents or translated text editions of the statutes of 13 towns on the eastern Adriatic coast written in 13th and 14th centuries have been examined. Results: The research of the selected archives revealed numerous examples of direct or indirect ways of protecting public health. Among these, the most explicit are the examples which describe the maintenance of public cleanliness and the management of garbage, faeces, dirty water, etc. Rules on healthy water and food are also mentioned. In addition, prostitutes, witches and fortune- tellers were especially treated as a potential threat to public health. Conclusion: The aforementioned rules are not only important from the historical point of view, but also as a reflection of people's awareness of public health as a condition of survival and progress.

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