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Sharma N.,Medical science and Research Institute
Journal of Clinical and Diagnostic Research | Year: 2013

A five day old full term born baby was admitted to our Neona-tal Intensive Care Unit with seizures, opisthotonous posture and was icteric upto thigh. Baby had a three day history of poor feed-ing, lethargy and abnormal body movements. Mother was a 29 years old primigravida and had a normal vaginal delivery at home. Sepsis profile of the patient was requested, lumbar puncture and ventricular tap was performed. Patient was put on third generation cephalosporins, aminoglycosides and phenobarbitone. Culture and sensitivity report of blood, Cerebro spinal fluid and ventricular fluid showed Proteus mirabilis. Computerized Tomography scan showed a large parenchymal lesion in the right frontal lobe and diffuse ependymal enhancement along both the lateral ventricles suggestive of meningoventriculitis. We hereby present a fatal case of neonatal meningoventriculitis due to Proteus mirabilis.

Sharma A.,Obstetrics and Gynecology | Thawani V.,Medical science and Research Institute
Journal of Pharmacology and Pharmacotherapeutics | Year: 2012

This is the first case report depicting masking of symptoms of intestinal tuberculosis by anabolic androgenic steroids (AAS) causing delay in diagnosis which lead to a major surgery. Negative tuberculosis skin test (TST) probably due to immunomodulating effects of AAS also contributed to the delay. Patient also had early dependence on AAS and rapid growth of scrotal sebaceous cysts, findings of which have not yet been reported.

Patil S.V.,Bharati Vidyapeeth Deemed University | Gaikwad P.B.,Medical science and Research Institute | Vaidya S.R.,Bharati Vidyapeeth Deemed University | Shinde S.,Bharati Vidyapeeth Deemed University | And 2 more authors.
Biomedicine (India) | Year: 2013

Background: Yoga is an ancient science established in India. Those who are practicing this life style lead to disciplined life. Aim: This work was undertaken to study the effects of short term pranayama on physical health of individual. Materials & Methods: The study was conducted on 60 healthy 1st year M.B.B.S. students to study the effects of pranayama on heart rate, blood pressure, breath holding time, 40 mmHg endurance test before and after 4th, 8th & 12th week of pranayama practice. Blood pressure & 40 mmHg endurance time was measured with the help of Sphygmomanometer & stop watch. Heart rate & breath holding time was measured with stop watch. Results: There was a significant decrease in heart rate after 4th week but highly significant decrease in heart rate occurs after 8th and 12th week of Pranayama practice. Also there was an increase in breath holding time & 40 mmHg endurance time; this was found to be statistically highly significant after 4th, 8 th & 12th week of Pranayama practice. There was a significant decrease in systolic BP after 4th week but highly significant decreases in systolic blood pressure occur after 8th and 12 th week. Also there was decrease in diastolic BP, but this change was not statistically significant. Conclusion: Regular practice of Pranayama is extremely beneficial in improving Cardio-pulmonary efficiency of the individual.

Sangwan J.,Medical science and Research Institute | Kumar S.,Armed Forces Medical College | Juyal D.,Medical science and Research Institute
Journal of Clinical and Diagnostic Research | Year: 2013

Mycobacterium fortuitum, an environmental organism, is capable of producing a variety of clinical infections such as cutaneous infections, abscesses and nosocomial infections. Rarely, it has been a documented as a cause of peritonitis in patients receiving continuous ambulatory peritoneal dialysis (CAPD). Continuous Ambulatory Peritoneal dialysis (CAPD) is one of the treatment options which are used for patients with end-stage renal disease (ESRD). Although peritonitis rates have declined in parallel with advances in peritoneal dialysis (PD) technology, peritonitis remains a leading complication of CAPD and it is the major cause for transfer to other methods of dialysis. We are reporting a case of M. fortuitum peritonitis in a patient who was undergoing CAPD, which was successfully treated. This case emphasizes the importance of mycobacterial cultures in patients with CAPD-associated peritonitis, whose routine cultures may yield no organisms.

Prakash R.,Medical science and Research Institute | Juyal D.,Medical science and Research Institute | Negi V.,Medical science and Research Institute | Pal S.,Medical science and Research Institute | And 3 more authors.
North American Journal of Medical Sciences | Year: 2013

Background: Chronic suppurative otitis media (CSOM) is a notorious infection and a major health problem in developing countries causing serious local damage and threatening complications. Early and effective treatment based on the knowledge of causative micro-organisms and their antimicrobial sensitivity ensures prompt clinical recovery and possible complications can thus be avoided. Aims: The aim of this study was to isolate the organisms associated with CSOM and to detect the antibiogram of the aerobic isolates. Materials and Methods: A total of 204 patients clinically diagnosed of CSOM were enrolled in the study and the samples were obtained from each patient using sterile cotton swabs and cultured for microbial flora. Drug susceptibility testing for aerobic isolates was conducted using Kirby-Bauer disc diffusion method. Results: The most common causative organisms isolated were Staphylococcus aureus (48.69%) and Pseudomonas aeruginosa (19.89%) amongst the 191 aerobic isolates. Anaerobes accounted for 29.41% of the isolates while 12.25% were fungi. Antimicrobial profile of aerobic isolates revealed maximum sensitivity to amikacin (95.5%), ceftriaxone (83.4%) and gentamicin (82.7%). Conclusion: Knowing the etiological agents of CSOM and their antimicrobial susceptibility is of essential importance for an efficient treatment, prevention of both complications and development of antibiotic resistance and finally, the reduction of the treatment costs.

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