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Blagonravov M.L.,Medical Institute of Russian University of People Friendship | Korshunova A.Y.,Medical Institute of Russian University of People Friendship | Azova M.M.,Medical Institute of Russian University of People Friendship | Bondar' S.A.,Medical Institute of Russian University of People Friendship | Frolov V.A.,Medical Institute of Russian University of People Friendship
Bulletin of Experimental Biology and Medicine | Year: 2016

In experiments on rabbits we evaluated the intensity of cardiomyocyte autophagia by the level beclin-1 protein and morphology of the left ventricular myocardium on days 1, 3, and 5 after the onset of focal ischemia caused by ligation of the descending branch of the left coronary artery. The morphological alterations in the left ventricular myocardium were accompanied by intensification of cardiomyocyte autophagia, which attained maximum on postligation day 1. © 2016 Springer Science+Business Media New York Source

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