News Article | May 4, 2017
BOSTON, May 4, 2017 /PRNewswire/ -- Third Pole Inc., a company developing next generation life-saving cardiopulmonary therapies, today announced that it has won Johnson & Johnson Innovation's JLABS @ M2D2 QuickFire Challenge. The JLABS @ M2D2 QuickFire Challenge awards one year of paid residence at the University of Massachusetts Medical Device Development Center (M2D2) in Lowell, Massachusetts and access to mentorship and coaching from Johnson & Johnson Innovation experts to the best medical device idea, technology, or solution that will address a critical health need for the world's population. Third Pole's first product is capable of creating an unlimited supply of pure nitric oxide (NO) on-demand from air, providing patients with access to life- saving therapy without requiring compressed gas cylinders. NO is a gas produced by the body to relax the smooth muscle around blood vessels. When inhaled, low doses of NO can selectively decrease the lung's blood vessel resistance without causing a dangerous drop in systemic blood pressure. In the last two decades, inhaled NO has become a standard of care and has been used for about a million patients worldwide, including term infants with acute pulmonary hypertension in the US and adults and children with pulmonary hypertension before and after cardiac surgery in other countries. The currently available tank-based system of delivering therapeutic gaseous NO, however, is outmoded and cumbersome, limiting NO to the largest hospitals in developed regions that have the infrastructure to transport, maintain, return and refill heavy compressed gas cylinders. Even in these markets, the large, heavy tanks hamper transport of patients within a hospital or between facilities, and make the use of NO nearly impossible outside of hospital settings. Third Pole's revolutionary technology electronically generates pure, functionally equivalent NO on site and on demand from air, enabling the use of inhaled NO for new therapies worldwide.
PubMed | Keimyung University and Medical Device Development Center
Type: Journal Article | Journal: PloS one | Year: 2016
Recently, smart mobile devices and wireless communication technologies such as WiFi, third generation (3G), and long-term evolution (LTE) have been rapidly deployed. Many smart mobile device users can access the Internet wirelessly, which has increased mobile traffic. In 2014, more than half of the mobile traffic around the world was devoted to satisfying the increased demand for the video streaming. In this paper, we propose a scalable video streaming relay scheme. Because many collisions degrade the scalability of video streaming, we first separate networks to prevent excessive contention between devices. In addition, the member device controls the video download rate in order to adapt to video playback. If the data are sufficiently buffered, the member device stops the download. If not, it requests additional video data. We implemented apps to evaluate the proposed scheme and conducted experiments with smart mobile devices. The results showed that our scheme improves the scalability of video streaming in a wireless local area network (WLAN).
PubMed | Gyeongsang National University, Daegu Gyeongbuk Institute of Science and Technology and Medical Device Development Center
Type: Journal Article | Journal: Journal of Korean Academy of Nursing | Year: 2016
The purpose of this study was to develop a wellness index for workers (WIW) and examine the validity and reliability of the WIW for assessing workers wellness.The developmental process for the instrument included construction of a conceptual framework based on a wellness model, generation of initial items, verification of content validity, preliminary study, extraction of final items, and psychometric testing. Content validity was verified by 4 experts from occupational health nursing and wellness disciplines. The construct validity, convergent validity and discriminant validity were examined with confirmatory factor analysis. The reliability was examined with Cronbachs alpha. The participants were 494 workers from two workplaces.Eighteen items were selected for the final scale, and the results of the confirmatory factor analysis supported a five-factor model of wellness with acceptable model fit, and factors named as physical emotional social intellectual occupational wellness. The convergent and discriminant validity were also supported. The Cronbachs alpha coefficient was .91.The results indicate that the WIW is a valid and reliable instrument to comprehensively assess workers wellness, and to provide basic directions for developing workplace wellness program.
Hwang J.,Alcatel - Lucent |
Byun S.-S.,Medical Device Development Center |
Byun S.-S.,Catholic University of Pusan
International Journal of Communication Systems | Year: 2015
During the last decade, a plentiful number of active queue management schemes have been proposed, but their main objectives are simply allocating the buffer resource to all flows evenly, or protecting responsive flows from being degraded by unresponsive flows. However, the sending rates of the responsive flows can be determined diversely, and not all unresponsive flows have aggressively high sending rates. Furthermore, it is rational to reserve a portion of the buffer resource for certain privileged traffic. Grounded by these evidences, in this paper, we present a resilient active queue management algorithm, named Prior-Core-based Buffer Allocation considering diverse congestion control algorithms, fair-unresponsive flows, and some privileged traffic. Our approach is based on stochastic cooperative game theory, where the payoffs yielded by cooperation are described by random variables, and the core is defined only over the distribution of these random payoffs; the core in this situation is called the prior-core. As a result, it is shown that our buffer allocation, yielded by the prior-core, achieves completely fair allocation for those flows whose requirement does not exceed the fair-share regardless of the responsiveness, whereas aggressive flows are restricted according to availability of the buffer; all these are verified through ns-2 simulation experiments. Copyright © 2014 John Wiley & Sons, Ltd.
Jafarfard M.R.,Yonsei University |
Tayebi B.,Yonsei University |
Lee S.,Medical Device Development Center |
Bae Y.-S.,Yonsei University |
Kim D.Y.,Yonsei University
Journal of the Optical Society of America A: Optics and Image Science, and Vision | Year: 2014
Volume measurement of a phase object is one of the most distinctive capabilities of quantitative phase microscopy (QPM). However, the accuracy of a measured volume is limited by the different noises of a measurement system and the finite bandpass filter used in the phase extraction algorithm. In this paper, we analyze the inherent errors in volume measurement with QPM and propose the optimum condition that can minimize these errors. We find that phase information of a sample in the frequency domain nonlinearly oscillates as a function of the phase shift corresponding to the sample and its medium, and that the phase information of a sample inside the bandpass filter can be maximized by a proper phase shift. Through numerical simulations and actual experiments, we demonstrate that the error in phase volume measurement can be effectively reduced by the enhancement of the phase signal inside the bandpass region using an optimum amount of phase, which can be controlled by changing either the medium index or the wavelength of illumination. © 2014 Optical Society of America.
Shin J.H.,Medical Device Development Center |
Chang M.S.,Korea Institute of Machinery and Materials |
Kim S.H.,Korea Institute of Machinery and Materials |
Jung D.S.,Korea Institute of Machinery and Materials
Transactions of the Korean Society of Mechanical Engineers, A | Year: 2014
Even the rough prediction of the product test time before the lifetime test of mechanical component begins would be of use in estimating cost and deciding how to keep up with the test. The reliability predictions of mechanical components are difficult because failure or degradation mechanisms are complicated, and few plausible databases are available for lifetime prediction. Therefore, this study conducted lifetime predictions of elastomeric U seals that were respectively installed in a hydraulic actuator and a pneumatic actuator using lifetime models and a field database based on failure physics and an actual test database obtained from the NSWC handbook. To validate the results, the predicted failure rates were compared with the actual lifetime test results acquired in the lab durability tests. Finally, this study discussed an engineering procedure to determine the coefficients in the failure rate models and analyzed the sensitivity of each influential parameter on the seal lifetime. © 2014 The Korean Society of Mechanical Engineers.