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Khanam N.,IMS & SUM Hospital | Sahu T.,IMS & SUM Hospital | Athavale A.V.,Chirayu Medical College & Hospital | Agarwal S.,PCMS & RC | And 2 more authors.
Journal of Datta Meghe Institute of Medical Sciences University | Year: 2016

Background: Vaginal discharge may be due to either physiological changes or sexually transmitted infections (STIs). STIs are major public health problem in India. This is further compounded because of our women’s cultural beliefs pertaining to various determinants of vaginal discharge. Objectives: To study the perception of women regarding causes and associated symptoms of vaginal discharge. Material and methods: Study was done in urban field practice area of department of community medicine, Peoples College of Medical Sciences & Research Centre (PCMS&RC), Bhopal. Qualitative in depth interview was done with women who had history of vaginal discharge. Study period was from July 2012 to September 2012. Open ended semi-structured questionnaire was used and community based cross sectional study was done with the help of social workers. Statistical analysis: The data was compiled, coded for all the responses and later entered in Excel sheet. Analysis was done, number and percentages were calculated. Results: Majority of the participants belonged to the age-group of 30-34 years (47.67%) and most of them (59.30 %) had studied primary schooling. Many of them were Hindus by Religion, followed by Muslim. Three fourth of the participants (73.26%) were house wife and 43.02% belonged to lower socio-economical class. Almost all of them said, vaginal discharge was because of visit of their husband to other women (97.67%) and because of poor personal hygiene of husband (96.51%). 77 (89.53%) of the participants perceived it as because of gynaecological problem. Almost all of them said, vaginal discharge led to weakness (98.83%) & backache (93.02%). Conclusion: There is need for raising awareness on sexually transmitted infections and also about health care facilities. Self concerns in women for their own health with behavioural changes require. © 2016, Datta Meghe Institute of Medical Sciences Deemed University. All rights reserved.

Kulkarni R.,Shri Aurobindo Institute of Medical science | Deshpande A.,Shri Aurobindo Institute of Medical science | Saxena K.,Chirayu Medical College & Hospital | Verma M.,MGM Medical College
Biomedical Research | Year: 2011

The role of Tumor Necrosis Factor alpha, Malondialdehyde and serum Iron in inducing anemia in Tuberculosis patients was studied. The present study was conducted in the De-partment of Biochemistry, Shri Aurobindo Institute of Medical Sciences, Indore. The study comprised of sixty-eight anemic pulmonary tuberculosis patients. Levels of Hemoglobin, Iron, TIBC, Ferritin, MDA & TNF α were analyzed in all of them. The inflammatory pa-rameters TNF α & Ferritin along with oxidative marker malondialdehyde were found to be increased in anemic tuberculosis patient and levels of Hb, iron & TIBC was decreased. Overall correlation shows that the levels of Hb, Iron & TIBC were negatively correlated to the levels of Ferritin, MDA & TNF α. Ferritin was negatively correlated with Iron (r = -0.261, p<0.05) & showed a positive correlation with MDA. (r = 0.304, p < 0.05). For Ferritin & TNF α correlation was positive, it was not significant (r = 0.114, NS).There was a positive significant correlation between Iron & TIBC. (r = 0.666, p<0.01) & a negative significant correlation between the TNF α levels and the hemoglobin concentration (r = -.273, p<0.05). Hypoferremia was induced as a consequence of inflammatory response and action of free radicals in anemic tuberculosis patients.

Kulkarni R.,Sri Aurobindo Institute of Medical science | Verma M.,MGM Medical College | Sinha A.,Chirayu Medical College & Hospital | Deshpande A.,Shri Aurobindo Institute of Medical science | Verma V.,MGM Medical College
Biosciences Biotechnology Research Asia | Year: 2010

To find out effect of antitubercular therapy on serum levels of Tumor necrosis factor alpha (TNF α) & Malondialdehyde (MDA). The present study was conducted in Department of Biochemistry and patients were selected from Department of TB & Chest Shri Aurobindo Institute of Medical sciences & Manorama Raje Tuberculosis hospital, Indore. 32 healthy controls and 35 Pulmonary TB Patients were compared initially for serum MDA and TNF à levels. The serum TNF α and MDA levels of PTB patients were again estimated after one month of antitubercular therapy. TNF a & MDA levels in serum were significantly increased (p<0.001) in pulmonary tuberculosis patients when compared with control. Antitubercular therapy significantly decreases TNF α & MDA levels (p<0.05). The study indicates that TNF α & MDA are the important parameters in evaluating the severity of disease and monitoring of the clinical effect of the antituberculosis drugs (DOTS) over a period of prescribed drug therapy.

Kulkarni R.,Shri Aurobindo Institute of Medical science | Deshpande A.,Shri Aurobindo Institute of Medical science | Saxena K.,Chirayu Medical College & Hospital | Varma M.,MGM Medical College | Sinha A.R.S.,Chirayu Medical College & Hospital
Indian Journal of Traditional Knowledge | Year: 2012

The study was aimed to establish ginger as a supplement in treatment of anemia along with iron supplements Sixty two patients aged between 18-55 yrs, suffering from anemia participated in the study. Blood sample was analyzed for hematological and iron related parameters before and after treatment. Hematological parameters and iron related parameters - plasma iron and plasma ferritin show increased and TIBC decreased by treatment in all the group patients. Per cent rise in hematological and iron related parameters, was calculated which indicates that the ginger and iron supplementation was found to be effective in correcting anemia and iron deficiency. It was concluded that ginger assist in iron absorption and found to be beneficial as a supplement in therapy of anemia.

Mangalgiri A.,Chirayu Medical College & Hospital | Mahore D.,Government Medical College | Kapre M.,Neeti Clinics
Indian Journal of Otolaryngology and Head and Neck Surgery | Year: 2014

Facial artery plays a key role in blood supply of the face. Facial artery one of the anterior branches of the external carotid artery originates within the carotid triangle. Variation in the origin of the facial artery was observed on two sides out of 60 sides in 30 cadavers. Facial artery was observed originating at the level just below the maxillary artery within the parotid gland. Facial artery may originate as linguo-facial trunk or thyro-linguo-facial trunk. Other developmental variations have also been described in the literature like, agenesis of facial artery, enlarged facial artery, hypoplastic facial artery. Variability in situation may complicate the surgery. Therefore maxillofacial surgeon, plastic surgeons and head & neck surgeon should be aware of such variation. © 2014, Association of Otolaryngologists of India.

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