Mazandran University of Medical science

Sari, Iran

Mazandran University of Medical science

Sari, Iran

Time filter

Source Type

Behzadkolaee S.M.A.,Health Science University | Mirmohammadi S.T.,Health Science University | Yazdani J.,Health Science University | Gorji A.M.H.,Mazandran University of Medical science | And 2 more authors.
Journal of Natural Science, Biology and Medicine | Year: 2015

Background: People spend a considerable part of their childhood time in the schools, a phase that coincides with their physical and mental growth. A healthy educational environment is vital to student's health and wellbeing. Materials and Methods: This study is a descriptive study conducted in 100 primary schools (both state and nonprofit schools) from Sari's Districts 1 and 2 in Iran. Sampling was performed by census and data were collected using the standard questionnaire by direct interview. Data were analyzed by Excel and SPSS software (Version 20.0. IBM Corp, Armonk), NY: IBM Corp using independent numerical T2 testing. Results: Significant relationship was observed between the kind of schools (P = 0.045) and their locations (P = 0.024), however the health, safety and environment (HSE) ratings among boys only versus girls only schools were similar (P = 0.159). Interestingly private and nongovernment schools and primary schools from Sari's districts one had consistently higher HSE ratings. Conclusion: The differential and higher HSE ratings in primary schools run by Private organizations and primary schools from Sari's districts one could be due to manager's awareness and implementation of recommended HSE standards, schools neglecting and overlooking these standards had lower HSE ratings. It is necessary that schools with lower HSE ratings are made aware of the guidelines and necessary infrastructures allocated to improve their HSE ratings.


Nesheli H.M.,Babol University of Medical Sciences | Nakhjavani N.,Babol University of Medical Sciences | Moghaddam T.G.,Mazandran University of Medical science
Caspian Journal of Internal Medicine | Year: 2011

Background: The Pelger-Huet anomaly dominantly is a rare and benign inherited defect of terminal neutrophil differentiation. Although neutrophil migration may be minimally impaired, granulocytes function is otherwise normal association abnormalities such as ocular, musculoskeletal are reported very rare. Case: An eight year-old boy with good consciousness but severe muscular atrophia and difficulty in respiration was admitted in Amirkola Hospital at Babol University of Medical Sciences Babol, Iran. The patient was febrile at presentation. The chest x-ray was normal and other causes of respiratory problem were ruled out. The patient and his mother have 30% to 40% band and Pelger-Huet cells in peripheral blood smear. He gradually has gotten hearing loss and decreased visual acuity for three years. He has optic nerve atrophia. Conclusion: The patient is an unusual type of Pelger-Huet anomaly with multiple organ dysfunctions probably due to simultaneous muscular degenerative disease.


Nesheli H.M.,Babol University of Medical Sciences | Tamaddoni A.,Babol University of Medical Sciences | Nesheli M.M.,Babol University of Medical Sciences | Yahyai A.,Mazandran University of Medical science | And 3 more authors.
Journal of the Pakistan Medical Association | Year: 2013

Objective: To evaluate hyperlipidaemia in patients with acute lymphoblastic leukaemia (ALL) receiving Lasparaginase. Methods: A case-control study carried out between October 2007 and October 2010 with 77 patients undergoing chemotherapy at a teaching children's hospital in Babol, Iran. Patients were treated with anti-leukaemic agents according to the protocols for standard-risk and high-risk ALL. Those patients who received asparaginase represented the cases and those who did not receive it were the controls. Biochemical markers were checked during the induction phase chemotherapy. Lipid profile of patients was recorded. Data was analysed using SPSS 16. Results: Of the 77 patients, 37 (48.05%) received asparaginase therapy and 40 (51.94%) patients did not. The mean peak triglyceride and cholesterol levels during asparaginase therapy in the first group were significantly higher than the levels in the second group. Conclusion: Severe hyperlipidaemia may be the cause of some morbidity in children receiving asparaginase. Asparaginase-induced hyperlipidaemia should be monitored in ALL patients during the induction phase of treatment.


Seyedi S.M.,University of Mazandaran | Roodbari F.,University of Mazandaran | Mohseni M.,University of Mazandaran | Hosseini S.H.,Mazandaran University of Medical Sciences | Alaei O.R.,Mazandran University of Medical science
Journal of Mazandaran University of Medical Sciences | Year: 2015

Background and purpose: Borna disease virus (BDV) is a unique RNA virus with wide range of hosts. There are many similarities in behavioral disorders caused by BDV in animals and certain mental disorders in human which suggests possible etiology of these disorders. The purpose of this study was to investigate the relationship between BDV and etiopathogenesis of psychiatric disorders, particularly schizophrenia and its prevalence in this group of patients. Material and methods: RNA was extracted from blood cell of 30 patients with schizophrenia and 15 healthy volunteers. It was screened for a 391-nucleotide, highly conserved region of the p24 and 447-nucleotideregion of the p40 of BDV, using specific primers and nested RT-PCR. Results: The mean age of the patients and controls were 36.03 ± 11.28 and 31.86 ± 10.61 years, respectively. BDV RNA was detected in eight patients with schizophrenia, while none of the healthy subjects was found infected with BDV. The prevalence of BDV virus was significantly higher in people with schizophrenia (26.66%) compared to that of the control group (P< 0.05). Conclusion: This study supports previous findings regarding the relationship between BDV and psychiatric disorders, especially schizophrenia. Therefore, this virus could be considered as an environmental factor that can increase the risk of mental illnesses in adults. © 2015, Mazandaran University of Medical Sciences. All rights reserved.


Najafi N.,Mazandran University of Medical science | Ghassemian R.,Mazandran University of Medical science | Davoody A.R.,Mazandran University of Medical science | Tayebi A.,Mazandran University of Medical science
BMC Research Notes | Year: 2011

Background: Brucella epididymoorchitis(BEO) is a focal complication of human brucellosis and has been reported in 2-20% of patients with brucellosis. Brucellosis is an endemic disease in Iran. The incidence of the disease in this country is 34 per 100 000 per year. Methods. In a retrospective study, we identified 30 cases of Brucella epididymoorchitis in two teaching hospitals in the north of Iran during 1997-2009. Findings. Epididymoorchitis occurred in 11.1% of male patients with brucellosis. The average age was 25.5 12.43 years. Pain and scrotal swelling (100%) and fever (96.7%) were the most common symptoms. Different treatment regimens were administered including doxycycline plus rifampin (60%), doxycycline plus rifampin plus aminoglycoside for the first two weeks (36.6%) and doxycycline plus cotrimoxazole(3.4%). Ten percent of the patients did not respond to antibiotic therapy and required surgical drainage or orchiectomy. Conclusions: In brucellosis endemic areas, clinicians who encounter patients with epididymoorchitis should consider the likelihood of brucellosis. A careful history and physical examination and an immediate laboratory evaluation help to make a correct diagnosis. Generally, classical therapy of brucellosis is adequate for the treatment of epididymoorchitis. © 2011 Davoody et al; licensee BioMed Central Ltd.


Fakheri H.,Mazandran University of Medical science | Zarghami M.,Mazandran University of Medical science | Shahsavari M.,Mazandran University of Medical science | Bari Z.,Mazandran University of Medical science | Yazdani J.,Mazandran University of Medical science
Govaresh | Year: 2011

Background: Many studies have investigated the effects of psychological factors on disease activity in patients with ulcerative colitis (UC). However, the number of studies that have assessed the correlation between immunologic markers of UC and psychological distress are few. Therefore, we designed a study to determine the association between two immuno-biological markers, peripheral/central anti-neutrophilic cytoplasmic antibodies (c-ANCA and p-ANCA), and depressive symptoms, healthy anxiety and personality traits. Materials and Methods: A total of 108 patients with UC entered the study. p-ANCA and c-ANCA were determined by enzymelinked immunosorbent assay (ELISA) and reconfirmed by indirect immunofluorescence. Severity of UC was classified based on Truelove criteria. Depressive symptoms were measured by the Center for Epidemiologic Studies-Depression (CES-D) Scale, anxiety symptoms by the Hospital Anxiety Depression (HAD) Scale and personality traits were assessed by the Revised Eysenck Personality Questionnaire. Pearson correlation was used to assess the relationship between p-ANCA/c-ANCA and psychological distress. Results : Our results showed that 81.5% of the patients suffered from anxiety, 43.5% suffered from depression and 75% suffered from introvert personality. No patient was positive for p-ANCA. There were 16 patients (14.8%) who tested positive for c-ANCA; 85.2% were negative for c-ANCA. Anxiety was significantly higher in the c-ANCA negative patients. Conclusion : According to our results, only testing negative for c-ANCA correlated with anxiety. However, the high prevalence of anxiety, depression and introversion and their roles in the clinical course and outcomes of the UC shows the need for early psychological intervention in those patients.


PubMed | Mazandran University of medical science
Type: | Journal: BMC research notes | Year: 2011

Brucella epididymoorchitis(BEO) is a focal complication of human brucellosis and has been reported in 2-20% of patients with brucellosis. Brucellosis is an endemic disease in Iran. The incidence of the disease in this country is 34 per 100 000 per year.In a retrospective study, we identified 30 cases of Brucella epididymoorchitis in two teaching hospitals in the north of Iran during 1997-2009.Epididymoorchitis occurred in 11.1% of male patients with brucellosis. The average age was 25.5 12.43 years. Pain and scrotal swelling (100%) and fever (96.7%) were the most common symptoms. Different treatment regimens were administered including doxycycline plus rifampin (60%), doxycycline plus rifampin plus aminoglycoside for the first two weeks (36.6%) and doxycycline plus cotrimoxazole(3.4%). Ten percent of the patients did not respond to antibiotic therapy and required surgical drainage or orchiectomy.In brucellosis endemic areas, clinicians who encounter patients with epididymoorchitis should consider the likelihood of brucellosis. A careful history and physical examination and an immediate laboratory evaluation help to make a correct diagnosis. Generally, classical therapy of brucellosis is adequate for the treatment of epididymoorchitis.


PubMed | Mazandran University of Medical science
Type: Journal Article | Journal: Medical archives (Sarajevo, Bosnia and Herzegovina) | Year: 2016

To investigate efficacy of remote ischaemic preconditioning on reducing kidney injury and myocardial damage after coronary artery bypass grafting surgery (CABG).Ischaemic preconditioning of a remote organ reduces ischaemia-reperfusion injury of kidney and myocardium after CABG.To reduce myocardial damage and kidney injury by applying Remote Ischaemic Preconditioning we recruited 100 consecutive patients undergoing elective coronary artery bypass grafting surgery. We applied three cycles of lower limb tourniquet, inflated its cuff for 5 minutes in study group or left un-inflated (sham or control group) before the procedure. The primary outcome was serum creatinine, creatinine clearance and troponin-I Levels at time 0, 6, 12, 24 and 48 h. Secondary outcomes were serum C-reactive protein, inotrope score, ventilation time and ICU stay. Datas were analyzed by MedCalc (MedCalc Software bvba, Acacialaan, Belgium). We compared the two group by student t test, chi-square and Mann-Whitney tests.The two groups were not statistically different in terms of age, gender, smoking habits, drug use, hypertension, hyperlipidemia and diabetes mellitus. This study showed a higher CRP level in study group comparing with control group (P=0.003), creatinine clearance was slightly higher in study group specially 24 h after procedure but was not statistically significant (p=0.11). Troponin-I level was significantly lower in study group (p=0.001).This study showed a lower Troponin-I level in study group which suggest a cardio-myocyte protective function of RIPC. It also showed slightly lower Creatinine clearance in control group, gap between two group increases significantly 24 hours after procedure which may suggest a potential kidney protection by RIPC. Serum CRP level was higher in study group. A multi-center randomized controlled trial with a longer time for creatinine clearance measurement may show the potential effectiveness of this non-invasive inexpensive intervention on reducing kidney injury after CABG.


PubMed | Health Science University, Education and Training Province Mazandran and Mazandran University of Medical science
Type: Journal Article | Journal: Journal of natural science, biology, and medicine | Year: 2015

People spend a considerable part of their childhood time in the schools, a phase that coincides with their physical and mental growth. A healthy educational environment is vital to students health and wellbeing.This study is a descriptive study conducted in 100 primary schools (both state and nonprofit schools) from Saris Districts 1 and 2 in Iran. Sampling was performed by census and data were collected using the standard questionnaire by direct interview. Data were analyzed by Excel and SPSS software (Version 20.0. IBM Corp, Armonk), NY: IBM Corp using independent numerical T2 testing.Significant relationship was observed between the kind of schools (P = 0.045) and their locations (P = 0.024), however the health, safety and environment (HSE) ratings among boys only versus girls only schools were similar (P = 0.159). Interestingly private and nongovernment schools and primary schools from Saris districts one had consistently higher HSE ratings.The differential and higher HSE ratings in primary schools run by Private organizations and primary schools from Saris districts one could be due to managers awareness and implementation of recommended HSE standards, schools neglecting and overlooking these standards had lower HSE ratings. It is necessary that schools with lower HSE ratings are made aware of the guidelines and necessary infrastructures allocated to improve their HSE ratings.

Loading Mazandran University of Medical science collaborators
Loading Mazandran University of Medical science collaborators