Maurizio Bufalini Hospital

Cesena, Italy

Maurizio Bufalini Hospital

Cesena, Italy
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News Article | May 22, 2017
Site: news.yahoo.com

Professional motorcycle racer died Monday after succumbing to injuries sustained from a crash in Italy five days earlier. He was 35. Before he died at Maurizio Bufalini Hospital in Cesena, Hayden had a net worth in the millions. Continue reading to find out how much money Hayden earned from racing. According to Celebrity Net Worth, Hayden was worth $18 million when he died. He was best known for winning the MotoGP World Championship in 2006 and went by the nickname “The Kentucky Kid.” READ: Who Is Nicky Hayden’s Fiancée, Jackie Marin? See Last Instagram Picture Together Hayden was training on a bicycle when he was hit by a car. He suffered chest and head trauma, which turned out to ultimately be deadly. Red Bull Honda World Superbike, who sponsored the former champion, issued a lengthy a statement after the racer’s Monday death. “It is with great sadness that Red Bull Honda World Superbike Team has to announce that Nicky Hayden has succumbed to injuries suffered during an incident while riding his bicycle last Wednesday,” the statement said. “Nicky passed away at 19:09 CEST this evening at Maurizio Bufalini Hospital in Cesena, Italy. His fiancée Jackie, mother Rose and brother Tommy were at his side.” The statement continued: “Nothing says more about Nicky’s character than the overwhelming response expressed by fellow racers and his legions of fans over the past few days. Jackie and his family are truly grateful for the countless prayers and well wishes for Nicky.” Hayden’s fiancée, Jackie Marin, did not immediately issue a statement after Hayden’s untimely death. However, Tommy, the racer’s brother, spoke on behalf of his family. “…I would like to thank everyone for their messages of support – it has been a great comfort to us all knowing that Nicky has touched so many people’s lives in such a positive way,” he said. “Although this is obviously a sad time, we would like everyone to remember Nicky at his happiest – riding a motorcycle. He dreamed as a kid of being a pro rider and not only achieved that but also managed to reach the pinnacle of his chosen sport in becoming World Champion. We are all so proud of that.” Tommy added: “Apart from these ‘public’ memories, we will also have many great and happy memories of Nicky at home in Kentucky, in the heart of the family. We will all miss him terribly,” Tommy wrote. “It is also important for us to thank all the hospital staff for their incredible support – they have been very kind. With the further support of the authorities in the coming days we hope to have Nicky home soon.” Funeral arrangements were not immediately known. In his final Twitter post, Hayden joked he was still trying to learn English after a fan told him to learn how to speak Italian. “Thanks Nicky today, you're always the number one for us. You must learn Italian and I need to learn English,” the fan wrote May 14. Hayden retweeted the post two days after. It was like 845 times and shared dozens of times.


News Article | May 22, 2017
Site: news.yahoo.com

Jackie Marin, the fiancée of ex-MotoGp champion Nicky Hayden, did not immediately release a statement after the motorcycle racer died Monday from injuries suffered in a bicycle crash five days earlier. He was 35 years old. In her last Instagram picture with Hayden, Marin celebrated their engagement in Italy. “1 year ago, yesterday, this guy made the best decision of his life,” she wrote two weeks ago. After news of his death broke, fans sent their condolences to Marin on Instagram. For those who don’t know, Marin starred on the reality show “The Tequila Sisters.” Aside from acting and reality TV, Marin also likes to box. “True to Jackie’s Hispanic heritage, she loves watching professional boxing and cheering on her favorite Mexican boxers,” the biography on her Facebook page says. She also wrote that she lvoes music and that “singing is what drives her to pursue a career in music and take the stage with her bold yet sultry voice.” Immediately after the collision, Hayden was treated at Maurizio Bufalini Hospital in Cesena for severe cerebral damage and multiple traumatic injuries. “The medical team has verified the death of the patient Nicholas Patrick Hayden, who has been undergoing care since last Wednesday May 17 in the intensive care unit of the Bufalini Hospital in Cesena following a very serious polytrauma which occurred the same day,” the hospital statement said. Hayden was hit by a black Peugeot car. The 30-year-old driver was being questioned by police, ESPN reported. The person’s name was not immediately revealed. Red Bull Honda World Superbike, who sponsored the champion, issued a statement. “It is with great sadness that Red Bull Honda World Superbike Team has to announce that Nicky Hayden has succumbed to injuries suffered during an incident while riding his bicycle last Wednesday,” the statement said. “Nicky passed away at 19:09 CEST this evening at Maurizio Bufalini Hospital in Cesena, Italy. His fiancée Jackie, mother Rose and brother Tommy were at his side.” Marin did not immediately issue a statement, but she was referenced in the message from Red Bull Honda World Superbike. “Nothing says more about Nicky’s character than the overwhelming response expressed by fellow racers and his legions of fans over the past few days. Jackie and his family are truly grateful for the countless prayers and well wishes for Nicky,” the statement said. “On behalf of the whole Hayden family and Nicky’s fiancée Jackie I would like to thank everyone for their messages of support – it has been a great comfort to us all knowing that Nicky has touched so many people’s lives in such a positive way,” he said. “Although this is obviously a sad time, we would like everyone to remember Nicky at his happiest – riding a motorcycle. He dreamed as a kid of being a pro rider and not only achieved that but also managed to reach the pinnacle of his chosen sport in becoming World Champion. We are all so proud of that.” Hayden was known as the “Kentucky Kid” and his brother wrote about how he would be missed. “Apart from these ‘public’ memories, we will also have many great and happy memories of Nicky at home in Kentucky, in the heart of the family. We will all miss him terribly,” Tommy wrote. “It is also important for us to thank all the hospital staff for their incredible support – they have been very kind. With the further support of the authorities in the coming days we hope to have Nicky home soon.”


Biasini A.,Maurizio Bufalini Hospital
Nursing children and young people | Year: 2014

Trauma from burns and scalds in children is more common and more damaging than in adults, and may indicate abuse. The main goal of intensive care of an acute burn is to limit the extent of the systemic insult. Effective treatment of such acute physiological changes requires experienced monitoring by multidisciplinary teams, following appropriate emergency protocols at specialised burn centres in cases of major trauma. First aid involves maintaining a patent airway, supporting circulation and respiration, arresting the burning, managing pain and distress, reducing infection and considering transfer to specialist care. Advances in techniques and treatment have increased survival rates and ultimate quality of life, but education and prevention programmes are still required at all levels to reduce the incidence of burns among children.


Calista D.,Maurizio Bufalini Hospital | Morri M.,Infermi Hospital
Giornale Italiano di Dermatologia e Venereologia | Year: 2017

BACKGROUND: To identify the prognostic factors and assess the outcome of a group of octogenarian patients who were diagnosed with cutaneous melanoma (CM) in the Department of Dermatology of the "M. Bufalini" Hospital, Cesena, Italy from 1996 to 2013. METHODS: From the 1136 consecutive patients in our database, we selected 82 patients (7.2%) diagnosed with CM at age 80 or older. Their major clinical and histopathologic parameters were extracted and matched with those of the residual 1054 younger patients. RE SULT S: Comparing our 82 patients with the group of 1054 patients with CM diagnosed in the same period, but at a younger age, we found that: 1) there was no significant difference regarding the patient's gender; 2) CM diagnosed in octogenarians was more frequently located on the head and neck (24.4% vs. 12.8%), and lower extremities (24.4% vs. 14.4%) (P=0.0001); 3) early diagnosis of CM (T1) was less frequent in octogenarians (31.7% vs. 62.6%), intermedium thickness CM (T2) was nearly the same in the 2 groups (15.8% vs. 16.5%), while diagnosis in category T3/T4 (42.6% vs. 21.0%) were significantly greater in octogenarians (P=0.0001); 4) ulceration was detected more frequently in octogenarians (18.3% vs. 10.7%) but the difference was not statistically significant. After a follow-up period of a median 58 months, 52 octogenarians (63.4%) were still alive and free from disease. Thirty of them (36.6%) had died, 14 (17.1%) of which because of melanoma. On the contrary, among the younger patients, 840 (81.6%) were alive, 132 (12.5%) died for melanoma and 75 (7.1%) for other causes. CONCLUSIONS: In our octogenarians, death for CM was not related to the old age but to the delayed diagnosis of cancer. Our results suggest that continuing educational programs for early diagnosis of CM should specifically include this segment of population. Copyright © 2017 Edizioni Minerva Medica.


Shi J.,U.S. National Institutes of Health | Yang X.R.,U.S. National Institutes of Health | Ballew B.,U.S. National Institutes of Health | Rotunno M.,U.S. National Institutes of Health | And 59 more authors.
Nature Genetics | Year: 2014

Although CDKN2A is the most frequent high-risk melanoma susceptibility gene, the underlying genetic factors for most melanoma-prone families remain unknown. Using whole-exome sequencing, we identified a rare variant that arose as a founder mutation in the telomere shelterin gene POT1 (chromosome 7, g.124493086C>T; p.Ser270Asn) in five unrelated melanoma-prone families from Romagna, Italy. Carriers of this variant had increased telomere lengths and numbers of fragile telomeres, suggesting that this variant perturbs telomere maintenance. Two additional rare POT1 variants were identified in all cases sequenced in two separate Italian families, one variant per family, yielding a frequency for POT1 variants comparable to that for CDKN2A mutations in this population. These variants were not found in public databases or in 2,038 genotyped Italian controls. We also identified two rare recurrent POT1 variants in US and French familial melanoma cases. Our findings suggest that POT1 is a major susceptibility gene for familial melanoma in several populations. © 2014 Nature America, Inc. All rights reserved.


Yang X.R.,U.S. National Institutes of Health | Brown K.,U.S. National Institutes of Health | Landi M.T.,U.S. National Institutes of Health | Ghiorzo P.,University of Genoa | And 13 more authors.
Pigment Cell and Melanoma Research | Year: 2012

Copy number variations (CNVs) have been shown to contribute substantially to disease susceptibility in several inherited diseases including cancer. We conducted a genome-wide search for CNVs in blood-derived DNA from 79 individuals (62 melanoma patients and 17 spouse controls) of 30 high-risk melanoma-prone families without known segregating mutations using genome-wide comparative genomic hybridization (CGH) tiling arrays. We identified a duplicated region on chromosome 4q13 in germline DNA of all melanoma patients in a melanoma-prone family with three affected siblings. We confirmed the duplication using quantitative PCR and a custom-made CGH array design spanning the 4q13 region. The duplicated region contains 10 genes, most of which encode CXC chemokines. Among them, CXCL1 (melanoma growth-stimulating activity α) and IL8 (interleukin 8) have been shown to stimulate melanoma growth in vitro and in vivo. Our data suggest that the alteration of CXC chemokine genes may confer susceptibility to melanoma. Published 2012. This article is a US Government work and is in the public domain in the USA.


Iafusco D.,The Second University of Naples | Massa O.,Bambino Gesu Childrens Hospital | Pasquino B.,Regional Hospital | Colombo C.,Bambino Gesu Childrens Hospital | And 14 more authors.
Acta Diabetologica | Year: 2012

Until early 2000, permanent and transient neonatal diabetes mellitus (NDM), defined as diabetes with onset within 6 weeks from birth that requires insulin therapy for at least 2 weeks, were considered exceedingly rare conditions, with a global incidence of 1:500,000-1:400,000 live births. The new definition of NDM recently adopted, that includes patients with diabetes onset within 6 months of age, has prompted studies that have set the incidence of the permanent form alone between 1:210,000 and 1:260,000 live births. Aim of the present work was to ascertain the incidence of NDM (i.e. permanent + transient form) in Italy for years 2005-2010. Patients referred to the Italian reference laboratory for NDM between years 2005 and 2010 and screened for mutations in common NDM genes (KCNJ11, ABCC8, and INS) and for uniparental isodisomy of chromosome 6 (UDP6) were reviewed. A questionnaire aimed at identifying NDM cases investigated in other laboratories was sent to 54 Italian reference centers for pediatric diabetes. Twenty-seven patients with NDM born between 2005 and 2010 were referred to the reference laboratory. In this group, a mutation of either KCNJ11, ABCC8 or INS was found in 18 patients, and a case with UDP6 was identified. Questionnaires revealed 4 additional cases with transient neonatal diabetes due to UDP6. Incidence of NDM was calculated at 1:90,000 (CI: 1:63,000-1:132,000) live births. Thus, with the definition currently in use, about 6 new cases with NDM are expected to be born in Italy each year. © 2011 The Author(s).


Calista D.,Maurizio Bufalini Hospital | Vitali P.,M Bufalini Hospital | Arcangeli F.,Maurizio Bufalini Hospital
Giornale Italiano di Dermatologia e Venereologia | Year: 2013

Aim. The purpose of this study was to investigate the disease-free time (DFT) and overall survival (OS) of patients with intermediate or high-risk cutaneous melanoma who were treated with conventional surgery alone, and to compare them with that of a second group of patients who were treated with surgery and SLN biopsy. Methods. A retrospective, single-centre study was performed at the Department of Dermatology of the "M. Bufalini" Hospital, Cesena, Italy based on data collected between January 1990 and December 2007. A total of 757 consecutive patients with stage I-II melanoma were identified: the former group (control group), treated with conventional surgery, was composed of 224 patients; the latter, treated with surgery and SLN biopsy (SLN biopsy group), was formed of 529 patients. Results. The 5-year disease free time (DFT) rate, estimated with Kaplan-Meyer, was 73.9% (95% CI: 67.5-79.2) in the control group, and 82.2% (95% CI: 78.6-85.3) in the SLN biopsy group. Although the DFT rate was significantly higher in the SLN group than in the control group in univariate analyses (P=0.004), this gain was lost in multivariate analysis (P=0.2). The 5-year overall survival (OS) rate was 88.4% (95% CI: 83.2-92.1) for the control group, and 87.9% (95% CI: 84.6-90.4) for the SLN biopsy group. Statistical comparison of specific OS was not statistically significant (P=0.93). Conclusion. On the basis of our follow-up data, we found that patients who underwent SLN biopsy technique experienced a reduction in the proportion of lymph nodal relapse, but DFT and OS were statistically equivalent between the two groups.


De Cunto A.,University of Trieste | Bensa M.,Maurizio Bufalini Hospital | Tonelli A.,E Medea Scientific Institute
Pediatric Neurology | Year: 2012

Hemiplegic migraine constitutes an unusual form, characterized by periodic attacks of migraine with a motor component (hemiplegia). Familial forms are dominantly inherited, and are attributable to mutations in genes encoding proteins involved in ion transportation, including ATP1A2, which codes for the α-2 isoform of the sodium-potassium adenosine triphosphatase, a P-type cation transport adenosine triphosphatase, and responsible for the so-called familial hemiplegic migraine type 2. We describe a 9-year-old boy affected by familial hemiplegic migraine, with a novel ATP1A2 gene mutation (c.1799T>C p.V600A) in exon 13. Long-term treatment with flunarizine resulted in a good clinical response and the prevention of further attacks. © 2012 Elsevier Ltd. All rights reserved.


PubMed | Maurizio Bufalini Hospital
Type: Journal Article | Journal: Nursing children and young people | Year: 2014

Trauma from burns and scalds in children is more common and more damaging than in adults, and may indicate abuse. The main goal of intensive care of an acute burn is to limit the extent of the systemic insult. Effective treatment of such acute physiological changes requires experienced monitoring by multidisciplinary teams, following appropriate emergency protocols at specialised burn centres in cases of major trauma. First aid involves maintaining a patent airway, supporting circulation and respiration, arresting the burning, managing pain and distress, reducing infection and considering transfer to specialist care. Advances in techniques and treatment have increased survival rates and ultimate quality of life, but education and prevention programmes are still required at all levels to reduce the incidence of burns among children.

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