Maulana Azad Medical College Associated Lok Nayak Hospital

Delhi, India

Maulana Azad Medical College Associated Lok Nayak Hospital

Delhi, India
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PubMed | Safdarjung Hospital & Vardhman Mahavir Medical College and Maulana Azad Medical College & Associated Lok Nayak Hospital
Type: Journal Article | Journal: Journal of clinical orthopaedics and trauma | Year: 2015

A little information is available in the orthopaedic literature on the clinical bedside assessment of the coronal plane deformities of the knee. We aim to explain the knee flexion test to make it useful for the clinicians and the students learning the art of orthopaedics.We describe the principle, pre-requisites, fallacy, and modification of the knee flexion test along with the illustrative case description that had genu valgum deformity of the left knee of tibial origin.The knee flexion test should be a part of clinical bedside assessment of the coronal plane deformities of the knee.


Goyal M.,Maulana Azad Medical College Associated Lok Nayak Hospital | Singh A.,Maulana Azad Medical College Associated Lok Nayak Hospital | Singh P.,Maulana Azad Medical College Associated Lok Nayak Hospital | Kapoor S.,Maulana Azad Medical College Associated Lok Nayak Hospital
Journal of Clinical and Diagnostic Research | Year: 2014

The Oromandibular Limb Hypogenesis Syndromes (OLHS) comprises a spectrum of disorders involving the tongue, mandible, and the limbs and are characterized by hypoplastic mandible, absence of the lower incisors, hypoglossia, digits and limbs abnormalities ranges from syndactyly to amelia. In this report, we report a case of OLHS with growth hormone deficiency as a cause of short stature, which has not been described previously to the best of our knowledge. Key Words:oromandibular limb hypogenesis syndrome, growth hormone deficiency, short stature.


PubMed | Maulana Azad Medical College & Associated Lok Nayak Hospital
Type: Journal Article | Journal: Journal of clinical orthopaedics and trauma | Year: 2016

Primary leiomyosarcoma of the bone is exceedingly rare. In this case, we describe a middle-aged female with a primary leiomyosarcoma of the distal femur. The patient was treated by hip disarticulation. The patient continues to be disease-free at one-year follow-up.


PubMed | Maulana Azad Medical College & Associated Lok Nayak Hospital
Type: Evaluation Studies | Journal: Journal of orthopaedic surgery (Hong Kong) | Year: 2015

To evaluate the outcome after single tendon transfer of the flexor carpi ulnaris (FCU) to the digital extensors for high radial nerve palsy.Records of 10 patients aged 16 to 43 (median, 27) years who underwent single tendon transfer of the FCU to the digital extensors for high radial nerve palsy secondary to closed (n=4) or open (n=4) diaphyseal humeral fractures or deltoid injection (n=2) were reviewed. Two of the patients with open fractures also underwent treatment for non-union in a staged manner. Grip strength (power grip and precision grip) was measured monthly using an automated dynamometer. The range of motion of the wrist, and metacarpophalangeal joints of the thumb and fingers was measured monthly using a goniometer.All patients were followed up for at least one year. Preoperatively, the overall power grip strength of the injured hands was about 1/5 of the normal hands. At 12 months, the mean improvement was 202.5% for overall power grip strength and 43% to 57% for precision grip strength parameters. Compared with the normal hands, the mean deficit of the operated hands was 39% for overall power grip strength and 32% to 37% for precision grip strength parameters. At 12 months, mean wrist extension was 50.4, with about 10 lag in finger and thumb extension. The mean total active motion was 86.7 in the operated wrists and 128.1 in normal wrists. The decrease in wrist flexion and ulnar deviation was 7.8 and 6.8, respectively.Single tendon transfer of the FCU is a viable option to restore hand function and strength following high radial nerve injuries.


PubMed | Maulana Azad Medical College & Associated Lok Nayak Hospital
Type: Journal Article | Journal: Journal of clinical orthopaedics and trauma | Year: 2015

Total knee arthroplasty is associated with significant perioperative blood loss which may necessitate blood transfusion. In this prospective randomised case control study we analysed the efficacy and safety of tranexamic acid in reducing perioperative blood loss and requirement of blood transfusion in total knee arthroplasty.Fourteen patients (group A) undergoing total knee replacement were given intravenous tranexamic acid twice, once ten minutes before tourniquet deflation and once after four hours. Thirteen patients (group B) were observed as a separate group without the administration of the drug. Total perioperative blood loss, need of blood transfusion and D-dimer assay were analysed subsequently.The average blood loss in the first group was 266.2ml and in the second group was 667.5ml (p<0.001). average requirement of transfusion in both the groups were 0.54 and 1.6 units of blood respectively (p<0.001). There was no case of deep vein thrombosis or any other untoward effects.Hence from these evidences it was concluded that administration of tranexamic acid during total knee replacement helps to reduce blood loss without increasing the risk of deep vein thrombosis.


PubMed | Maulana Azad Medical College Associated Lok Nayak Hospital
Type: Journal Article | Journal: Journal of clinical and diagnostic research : JCDR | Year: 2014

The Oromandibular Limb Hypogenesis Syndromes (OLHS) comprises a spectrum of disorders involving the tongue, mandible, and the limbs and are characterized by hypoplastic mandible, absence of the lower incisors, hypoglossia, digits and limbs abnormalities ranges from syndactyly to amelia. In this report, we report a case of OLHS with growth hormone deficiency as a cause of short stature, which has not been described previously to the best of our knowledge.


PubMed | Maulana Azad Medical College & Associated Lok Nayak Hospital
Type: Case Reports | Journal: Acta orthopaedica et traumatologica turcica | Year: 2012

Tuberculosis is one of the oldest diseases affecting mankind and is known for its ability to present in various forms and guises. Pubic symphysis is an uncommon site for tuberculous affliction; hence very few cases have been reported in the English-language literature. We present a rare case of pubic symphysis tuberculosis diagnosed as osteitis pubis before presentation to our institution. The patient made an uneventful recovery following antitubercular chemotherapy.


PubMed | Maulana Azad Medical College & Associated Lok Nayak Hospital
Type: Journal Article | Journal: Human immunology | Year: 2011

The development and resolution of an inflammatory process is regulated by a complex interplay among cytokines that have pro- and anti-inflammatory effects. Regulatory mechanisms that control the production of cytokines include genetic polymorphism in particular promoter/leader region. Polymorphisms may directly or indirectly affect the binding of transcriptional factors, consequently increasing or decreasing the production of mRNA, thus regulating cytokine production. A total of 70 hepatitis C virus (HCV) RNA-positive patients and 70 healthy control subjects were included in the present study, who were attending the medical outpatient department (OPD) and wards of a tertiary care hospital in New Delhi during 2006-2008. This study was designed to determine the polymorphism of tumor necrosis factor- and interleukin-10 genes in patients with chronic HCV infection patients and their effect on pegylated interferon- therapy response. Polymorphism in the tumor necrosis factor- G/G, G/A, and A/A genotype was significant between HCV patients and healthy controls. Interleukin-10 variants (G/G, G/A) were nonsignificant among HCV patients compared with healthy controls. As this is a preliminary study on small sample size, we believe that our findings may stimulate further studies on larger number of patients from this geographic region.


PubMed | Maulana Azad Medical College & Associated Lok Nayak Hospital
Type: Comparative Study | Journal: Journal of cosmetic dermatology | Year: 2015

Xanthelasma Palpebrarum is a type of xanthoma which presents as cosmetic concern.To compare the efficacy of 30% TCA and UpCO2 laser in XP.Fifty patients with XP were categorized clinically into three groups. Patients in each group were alternately allocated to 30% TCA (Group A) and laser (Group B). TCA was applied weekly (maximum: 12 sessions), and laser sessions were given monthly (maximum: three sessions). The primary outcome measures were total patients cured, the number of sessions, and mean VAS at the end of treatment. The secondary outcome measures were total duration of treatment, side effects, and recurrence in follow-up (6 months) (P < 0.05 significant).In Group A, 14 of 25 and in Group B, 25 of 25 patients achieved complete cure (P < 0.05). The mean VAS was lower for Group A (patient: 4.56 vs. 5.36; physician: 4.64 vs. 5.44) [P < 0.05] with significant difference only for group III patients. Mean number of sessions was less with laser group (1.56 vs. 9.74), except in group I. There was no significant difference in pigmentary changes and recurrence.For clinically mild lesions, both TCA and laser are good options, but laser is a better option for severe lesions. Recurrence is a concern with both modalities.


PubMed | Maulana Azad Medical College & Associated Lok Nayak Hospital
Type: Comparative Study | Journal: The Brazilian journal of infectious diseases : an official publication of the Brazilian Society of Infectious Diseases | Year: 2013

Hepatitis C virus infects over 15 million patients from India and 2.86 million from Brazil. Detection of anti-hepatitis C virus antibodies has limited sensitivity during acute phase: the pre-seroconversion window period. Hepatitis C virus-RNA detection techniques are used to overcome this shortfall, but are costly and unavailable widely in developing countries. Estimation of hepatitis C virus core-antigen, a protein with highly conserved sequence, by enzyme-immunoassays is an economic and simpler alternative to RNA detection. This study was conducted in Delhi, involving 300 acute and chronic liver disease patients, tested for anti-hepatitis C virus 3rd-generation ELISA, hepatitis C virus core-antigen-ELISA and hepatitis C virus-RNA reverse transcription-polymerase chain reaction. Among the acute patients, hepatitis C virus core-antigen assay could identify 13 out of 14 pre-seroconversion window period cases and 6 out of 8 seroconverted cases, with a pre-seroconversion window period sensitivity of 92.9% and specificity of 100%. In hepatitis C virus core-antigen-positive cases, the viral load was in the range of 4900 to 1.4610(6)IU/mL, whereas in hepatitis C virus core-antigen-negative cases, the range of viral load was 100-4500IU/mL. The cost of the hepatitis C virus core-antigen-ELISA was estimated around 3-4 times lesser than the in-house reverse transcription-polymerase chain reaction and 9-10 times lesser than the United States Food and Drug Administration approved reverse transcription-polymerase chain reaction. With a good sensitivity and specificity in the acute phase of infection, hepatitis C virus core-antigen-ELISA can thus be a useful alternative in the developing nations.

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