Maulana Azad Medical College And Associated Ln Hospital

Delhi, India

Maulana Azad Medical College And Associated Ln Hospital

Delhi, India
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Singh A.P.,Maulana Azad Medical College And Associated Ln Hospital | Malhotra V.,Maulana Azad Medical College And Associated Ln Hospital | Brar T.,Maulana Azad Medical College And Associated Ln Hospital | Agarwal A.K.,Maulana Azad Medical College And Associated Ln Hospital | Khurana N.,Maulana Azad Medical College And Associated Ln Hospital
Indian Journal of Tuberculosis | Year: 2010

Tuberculosis continues to be a major public health problem. This disease has varying presenting features. We here present a case of primary tuberculosis of the nose with intracranial extension, a very rare presenting feature of tuberculosis.


Gupta A.,Ln Hospital | Gupta A.,Maulana Azad Medical College And Associated Ln Hospital | Kumar A.,Maulana Azad Medical College And Associated Ln Hospital | Arora S.,Maulana Azad Medical College And Associated Ln Hospital
Indian Journal of Tuberculosis | Year: 2016

Background Combined chemo- and immunotherapy are the major advancement in the treatment of tuberculosis. Immunotherapy supposedly increases cure rate while reducing the duration of treatment and tissue damage. Non-responders are those patients of tuberculosis who do not respond to anti-tubercular therapy (ATT) in the desired manner despite the mycobacteria showing sensitivity to the given drugs. The role of immunotherapy in the treatment of this particular subset of patients has been investigated scarcely. Methods The present study included a retrospective review of prospectively collected clinico-radiological data of 14 non-responder patients who were taking ATT for spinal tuberculosis for a mean duration of 10.3 months. An immunotherapeutic regime comprising of single intramuscular injection of vitamin D 600,000 IU, 3 days course of oral albendazole 200 mg daily, salmonella vaccine 0.5 ml intramuscular and influenza vaccine 0.5 ml intramuscular were added to ATT. The vaccines and the course of oral albendazole were repeated after a month. Results Before immunotherapy, seven patients were partially dependent while other seven were completely dependent on others for activities of daily living. All except one patient after treatment became independent till last follow-up (p value <0.01). Post immunotherapy, ATT was continued for mean duration of 4.9 months with mean follow-up of 22.4 months. All patients showed good clinical response within 2–6 weeks after the initiation of immunotherapy. Conclusions The crux to success of the immunotherapy regime is its potential to restore the existing Th1 Th2 imbalance and to provide substitute to the anergic and dysfunctional immune cells. © 2015 Tuberculosis Association of India


PubMed | Maulana Azad Medical College And Associated Ln Hospital
Type: Case Reports | Journal: The Indian journal of tuberculosis | Year: 2010

Tuberculosis continues to be a major public health problem. This disease has varying presenting features. We here present a case of primary tuberculosis of the nose with intracranial extension, a very rare presenting feature of tuberculosis.

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