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Bunkyo-ku, Japan

Matsuyama University is a private university in Matsuyama, Ehime, Japan. The predecessor of the school was founded in 1923, and it was chartered as a university in 1949. The present name was adopted in 1989. Shiho Ochi and Kōichi Tabo of Superfly are alumni. Wikipedia.

We have recently shown that 3,5,6,7,8,3#x2032;,4#x2032;-heptamethoxyflavone (HMF) and auraptene (AUR) have neu-roprotective effects on the central nervous system. HMF, a citrus flavonoid, altered NMDA-type glutamate receptor antagonist MK-801-induced memory dysfunction and schizophrenia-positive symptom-like behavior. HMF also showed a protective effect against ischemia-induced short-term memory dysfunction. In the ischemic brain, HMF induced the following protective effects against brain dysfunction: 1) rescue of neuronal cell death in the hippocampus; 2) increased production of brain-derived neurotrophic factor; 3) stimulation of neurogenesis in the dentate gyrus subgranular zone; 4) activation of the autophosphorylation of calcium—calmodulin-dependent protein kinase II; and 5) suppression of microglial activation. On the other hand, AUR, a citrus coumarin, ameliorated lipopolysaccharide-induced inflammation in the brain as shown by inhibition of microglial activation and inhibition of cyclooxygenase (COX) -2 expression in the hippocampus. AUR also showed antiinflammatory effects on the ischemic brain by inhibiting microglial activation, COX-2 expression, and neuronal cell death in the hippocampus. The peel of kawachibankan (Citrus kawachiensis),a noted citrus product of Ehime prefecture, Japan, contains AUR, HMF, naringin, and narirutin. The dried powder of both the peel and juice had antiinflammatory effects in the mouse hippocampus, suggesting that citrus compounds may be beneficial as neuroprotective agents in the treatment of neurological disorders. © 2015 The Pharmaceutical Society of Japan. Source

Mizobuchi K.,Matsuyama University | Takeuchi K.,Kobe University
Energy Policy | Year: 2016

This study examined the influence of additional and replacement purchases of energy-efficient air-conditioners on power savings. We used a questionnaire survey and measured electricity use data from 339 Japanese households, collected from two city areas with different level of government-requested electricity-saving rates, namely, Osaka (10%) and Matsuyama (5%). The main findings of our study are as follows: (1) Households that purchased energy-efficient air-conditioners saved more electricity than those that did not. (2) "Additional-purchase households" showed significant energy savings, whereas "replacement households" did not. The rebound effect may negate the energy-saving effects of a new air-conditioner. (3) Altruistic attitude is associated with more active participation in power saving. (4) Households in Osaka saved more electricity than those in Matsuyama, probably because the government call to save electricity was more forceful. © 2016 Elsevier Ltd. Source

Yoshimura M.,Matsuyama University
Yakugaku Zasshi | Year: 2014

Tannins and related polyphenols have been reported to produce diverse biological effects that indicate their therapeutic potential, including antioxidative, antibacterial, and antiviral activities. In an exploratory study of natural antioxidants with biological effects, we investigated the tannin constituents of myrtaceous plants reported to be rich in polyphenols. We isolated 16 new compounds from five species of the Melaleuca, Eucalyptus, Syzygium, Pimenta,and Myrtus genera. Among the new polyphenols, nine were isolated from Melaleuca squarrosa and characterized as C-gluco-sidic ellagitannin monomers and oligomers. The structures of the other new polyphenols from myrtaceous plants and a novel compound obtained from the berries of Pyracantha coccinea (Rosaceae) were also elucidated based on spectroscopic and chemical evidence. The antioxidative activity of isolates in the present study was estimated by measuring 1,1-diphenyl-2-picrylhydrazyl radical (DPPH)-scavenging activity and in the oxygen radical absorbance capacity (ORAC) test. We found that oenothein B, a macrocyclic ellagitannin dimer, is widely distributed in the genus Eucalyptus and produces a significant immunomodulatory effect on human dendritic cells (DCs). In a survey of natural ligands that bind to the aryl hydrocarbon receptor (AhR), nepitrin, a flavonoid glycoside, and other polyphenols were revealed to be promising therapeutic candidates. © 2014 The Pharmaceutical Society of Japan. Source

Mizobuchi K.,Matsuyama University | Takeuchi K.,Kobe University
Energy Policy | Year: 2013

This study examines the influences of financial and non-financial factors on electricity-conservation behaviour. A random sample of 236 Japanese households participated in the field experiment and the participants were offered two interventions, such as monetary rewards, depending on their reduction in electricity consumption and comparative feedback. The average saving rates of the (i) reward-intervention group (5.9%) and the (ii) reward with comparative feedback group (8.2%) are statistically larger than those of the (iii) control group (1.7%). Our study demonstrates the following. First, our econometric analysis confirmed a significant response by households to financial incentives but a more inconclusive response to the treatment that provided non-financial, additional information. Second, we found a positive influence of treatment externalities across time and households on energy saving. Third, there is a heterogeneous treatment effect in the reward-intervention group, with the households having a high New Ecological Paradigm (NEP) score being more likely to respond to the reward programme and save electricity than those that do not. Finally, and most interestingly, differences in responses to the questionnaire before and after the experiment suggest that the participants had underestimated the marginal costs of saving electricity before they actually started to do so. © 2013 Elsevier Ltd. Source

Koshima H.,Matsuyama University | Takechi K.,Matsuyama University | Uchimoto H.,Matsuyama University | Shiro M.,Rigaku Corporation | Hashizume D.,RIKEN
Chemical Communications | Year: 2011

Platelike microcrystals of N-3,5-di-tert-butylsalicylidene-3-nitroaniline repeatedly bend and straighten upon alternate irradiation with UV and visible light. The mechanism of bending was elucidated by X-ray crystallographic analyses before and after photoirradiation. © 2011 The Royal Society of Chemistry. Source

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