Materion Brush Inc. and Brush Wellman Inc | Date: 2011-01-14
Materion Brush Inc. and Brush Wellman Inc | Date: 2012-07-31
Materion Brush Inc. and Brush Wellman Inc | Date: 2010-04-13
Ultrahigh purity beryllium foil used for x-ray and gamma ray windows and other high energy physics applications.
Materion Brush Inc. and Brush Wellman Inc | Date: 2012-05-22
Metal matrix composites in the form of bars, sheets, panels, plates, and machined blanks composed of a metal matrix combined with a reinforcing material for use in further manufacture.
Deubner D.C.,Materion Brush Inc. |
Roth H.D.,Roth Associ.
Journal of Occupational and Environmental Medicine | Year: 2015
Purpose: This study explores how highly correlated time variables (occupational cohort time scales) contribute to confounding and ambiguity of interpretation. Methods: Occupational cohort time scales were identified and organized through simple equations of three time scales (relational triads) and the connections between these triads (time scale web). The behavior of the time scales was examined when constraints were imposed on variable ranges and interrelationships. Results: Constraints on a time scale in a triad create high correlations between the other two time scales. These correlations combine with the connections between relational triads to produce association paths. High correlation between time scales leads to ambiguity of interpretation. Conclusions: Understanding the properties of occupational cohort time scales, their relational triads, and the time scale web is helpful in understanding the origins of otherwise obscure confounding bias and ambiguity of interpretation. Copyright © 2015 by American College of Occupational and Environmental Medicine.
Heldt G.H.,Materion Brush Inc. |
Deubner D.C.,Materion Brush Inc.
Inhalation Toxicology | Year: 2015
Context: We had available records on over 300 workers evaluated with the beryllium bronchoalveolar lavage lymphocyte proliferation test (BeBALLPT) at three expert chronic beryllium disease (CBD) diagnostic centers. Objective: The objective was to describe the contribution of the BeBALLPT to classification of workers with respect to beryllium sensitization (BeS) and beryllium-induced lung inflammation. Methods: Company records were used to identify beryllium workers who had undergone diagnostic bronchoscopy with BeBALLPT. Clinical, work and smoking information was abstracted from electronic and paper databases. We analyzed factors influencing BeBALLPT outcome, and its relation to blood-determined BeS and granulomatous inflammation. Results: Positive BeBALLPTs contributed evidence of BeS in subjects without prior positive beryllium blood lymphocyte proliferation tests (BeBLPTs) and of pulmonary inflammation in persons without granulomata evident on lung biopsy. Positive BeBALLPTs were associated with positive BeBLPTs and more strongly with granulomata. The rate of both positive BeBALLPT and granulomata increased with time worked through 4 years and were lower in smoking subjects. The false negative rate of the BeBALLPT was 20%. Conclusion: A positive BeBALLPT is closely linked to the presence of granulomata on lung biopsy and can be considered as an indicator of lung inflammation in addition to BeS. The ability to use BeBALLPT as a substitute for the more risky lung biopsy is limited by the BeBALLPT false negative rate and lack of information on the false positive rate. It is not recommended that a positive BeBALLPT be considered sufficient evidence for both lung inflammation and BeS. © 2015 Informa Healthcare USA, Inc.
Deubner D.C.,Materion Brush Inc.
Journal of Occupational and Environmental Medicine | Year: 2013
Objective: Common variation is a statistical process-control term for variability associated with usual operating conditions. Special variation occurs when usual operating conditions are disrupted. The objective was to explore the implications for preventive occupational medicine practice of common and special variation in air-level exposure. Methods: Illustrations are derived from US and UK beryllium facility databases. Results: Special variation may be missed in finite sampling sets, giving a very inaccurate indication of the highest air levels experienced on the job. Depending on the toxicologic model, failure to assess special variation influences the meaningfulness of aspects of occupational prevention, from medical surveillance through risk management. Conclusions: Jobs and tasks should be characterized for special variation in addition to traditional air sampling. Both special variation and common variation should be considered in occupational medicine preventive practice. Copyright © 2013 by American College of Occupational and Environmental Medicine.
Materion Brush Inc. | Date: 2012-04-23
Aluminum beryllium investment castings used for automotive, aerospace construction, electronic, marine and medical product applications.
Materion Brush Inc. | Date: 2012-12-18
Materion Brush Inc. | Date: 2013-03-22
The Be content of Be Al alloys suitable for investment casting, which contain a small but suitable amount of Ag, can be significantly reduced without adversely affecting their thermal or investment casting properties by including significantly more Si in the alloy than done in the past.