Detroit, MI, United States
Detroit, MI, United States

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Patent
Mason Inc | Date: 2016-12-02

A device for connecting base station(s) to a cellular label switched network in a cellular network. The cellular network includes: base station(s), the connecting device(s); cellular label switched network(s); and service area(s). The base station(s) communicates with mobile terminals using wireless technology. The wireless technology uses a protocol layer architecture that includes at least one of the following: a wireless physical layer; a wireless medium access control protocol layer; a radio link control layer; and a network layer. The connecting device(s) include: a first interface to connect to the base station(s); a second interface to connect to cellular label switched network(s); and a label forwarding layer that: forwards packets between base station(s) and cellular label switched network(s); attaches label(s) to packets and removes label(s) from packets. A service area divided into a multitude of cells through which mobile terminals can move through and communicate with base station(s).


Patent
Mason Inc and Instituto Superiore Of Sanita | Date: 2014-09-04

Disclosed herein are: 1) methods for determining the appropriate drug therapy for a patient with colorectal cancer that has metastasized to the patients liver and/or lung; 2) methods for treating such a patient; and 3) pharmaceutical compositions for such treatment.


Antidepressants are among the most widely prescribed medications, yet only 35-45% of patients achieve remission following an initial antidepressant trial. The financial burden of treatment failures in direct treatment costs, disability claims, decreased productivity, and missed work may, in part, derive from a mismatch between optimal and actual prescribed medications. The present 1 year blinded and retrospective study evaluated eight direct or indirect health care utilization measures for 96 patients with a DSM-IV-TR diagnosis of depressive or anxiety disorder. The eight measures were evaluated in relation to an interpretive pharmacogenomic test and reporting system, designed to predict antidepressant responses based on DNA variations in cytochrome P450 genes (CYP2D6, CYP2C19, CYP2C9 and CYP1A2), the serotonin transporter gene (SLC6A4) and the serotonin 2A receptor gene (5HTR2A). All subjects had been prescribed at least one of 26 commonly prescribed antidepressant or antipsychotic medications. Subjects whose medication regimen included a medication identified by the gene-based interpretive report as most problematic for that patient and are in the 'red bin' (medication status of 'use with caution and frequent monitoring'), had 69% more total health care visits, 67% more general medical visits, greater than three-fold more medical absence days, and greater than four-fold more disability claims than subjects taking drugs categorized by the report as in the green bin ('use as directed') or yellow bin ('use with caution'). There were no correlations between the number of medications taken and any of the eight healthcare utilization measures. These results demonstrate that retrospective psychiatric pharmacogenomic testing can identify past inappropriate medication selection, which led to increased healthcare utilization and cost.


Patent
Mason Inc | Date: 2016-05-02

A cationic antimicrobial peptide (CAMP) conjugate is disclosed. The CAMP conjugate may be made by identifying a suitable carrier peptide; identifying a suitable antimicrobial agent; creating a conjugate by conjugating the peptide with the antimicrobial agent; and evaluating and refining the conjugate. The peptide may be short peptide based on the sequence of a CAMP, such as human -defensin-3. The peptide can be directly connected to the antimicrobial agent or through a linker segment. The antimicrobial agent may be connected to the peptide or the linker segment through stable or cleavable bonding. The peptide may carry and facilitate the delivery of the conjugated antimicrobial agent to a microbe.


Patent
Mason Inc and Rush University | Date: 2015-06-05

The present invention relates to methods and compositions for diagnosing, monitoring, prognosticating, analyzing, etc., polymicrobial diseases. The present invention also relates to the microbial community present in the digestive tract and lumen in normal subjects, and subjects with digestive tract diseases, especially diseases of the colon, such as inflammatory bowel disease, including ulcerative colitis, Crohns syndrome, and pouchitis. The present invention especially relates to compositions and methods for diagnosing and prognosticating the mentioned diseases and conditions, e.g., to determine the presence of the disease in a subject, to determine a therapeutic regimen, to determine the onset of active disease, to determine the predisposition to the disease, etc.


A computer system may be employed to verify program execution integrity by receiving a request to launch a program that has been instrumented to include at least one integrity marker, instantiating the program with an integrity marker value, and verifying the execution integrity of the program based on the integrity marker value and information received from the program during execution. A computer system may also be employed for program instrumentation by modifying the program to include at least one instruction for passing an integrity marker value to an operating system kernel during execution of the instruction.


Patent
Mason Inc | Date: 2015-07-24

Processor(s) for detecting malicious software. A hardware virtual machine monitor (HVMM) operates under a host OS. Container(s) initialized with network application template(s) operate under a guest OS VM. A detection module operates under the guest OS VM includes a trigger detection module, a logging module and a container command module. The trigger detection module monitors activity on container(s) for a trigger event. The logging module writes activity report(s) in response to trigger event(s). The container command module issues command(s) in response to trigger event(s). The command(s) include a container start, stop and revert commands. A virtual machine control console operates under the host OS and starts/stops the HVMM. A container control module operates under the guest OSVM and controls container(s) in response to the command(s). The server communication module sends activity report(s) to a central collection network appliance that maintains a repository of activities for infected devices.


Patent
Mason Inc | Date: 2014-08-22

A hardware-assisted integrity monitor may include one or more target machines and/or monitor machines. A target machine may include one or more processors, which may include one or more system management modes (SMM). A SMM may include one or more register checking modules, which may be configured to determine one or more current CPU register states. A SMM may include one or more acquiring modules, which may be configured to determine one or more current memory states. A SMM may include one or more network modules, which may be configured to direct one or more communications, for example of one or more current CPU register states and/or current memory states, to a monitor machine. A monitor machine may include one or more network modules and/or analysis modules. An analysis module may be configured to determine memory state differences and/or determine CPU register states differences.


Patent
Mason Inc | Date: 2014-09-09

An embodiment for providing a secure virtual browsing environment includes creating a virtual browsing environment with a virtualized operating system sharing an operating system kernel of a supporting operating system and executing the browser application within the virtual browsing environment. Another embodiment includes receiving a website selection within a browser application, determining if the website selection corresponds to a secure bookmark, and creating a second virtual browsing environment and executing the browser application within the second virtual browsing environment to access the website selection when the website selection corresponds to a website specified as a secure bookmark. Yet another embodiment includes monitoring operation of the operating system within the at least one virtual browsing environment, determining when the operation of the operating system includes potential malicious activity, and terminating the virtual browsing environment when the operation includes potential malicious activity.


Patent
Mason Inc | Date: 2014-04-01

An observable behavior data collection and analysis system including at least two database collection modules and an analysis module. The database collection module(s) include a parameter storage module, an observable behavior data prompt module, an observable behavior data collection module, a collection phase assignment module, and a server storage module. An instructor observes a subject performing a prompted task and enters the observed data into one of the database collection modules. The data is stored on a server. The analysis module, which includes a filter module and an output generation module, reads the data from the server and generates interactive graphs that may be used by the instructor to treat the subject.

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