Marine Biological Association of The United Kingdom
Plymouth, United Kingdom

The Marine Biological Association of the United Kingdom is a learned society with a scientific laboratory that undertakes research in marine biology. The organisation was founded in 1884 and has been based in Plymouth since the Citadel Hill Laboratory was opened on 30 June 1888. It has a world-leading reputation for marine biological research, with some twelve Nobel laureates having been or being associated with it over the course of their career. Among them, A. V. Hill received the Nobel Prize in Physiology or Medicine in 1922 "for his discovery relating to the production of heat in the muscle". The discovery of the mechanism of nerve impulses in animals was made at the Laboratory in Plymouth by Sir Alan Lloyd Hodgkin and Sir Andrew Huxley, work for which they were awarded the Nobel Prize for Physiology or Medicine in 1963. The MBA publishes the Journal of the Marine Biological Association of the United Kingdom. The MBA is also home to the National Marine Biological Library, whose collections cover the marine biological science, and curates the Historical Collections.In 2013, the MBA was granted a Royal Charter in recognition of the MBA's scientific preëminence in its field. Wikipedia.

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Agency: European Commission | Branch: H2020 | Program: CSA | Phase: INFRADEV-2-2015 | Award Amount: 975.52K | Year: 2015

EMBRC is a distributed infrastructure of marine biology and ecology, encompassing aquaculture and biotechnology, exploiting the latest omics, analytical and imaging technologies, and providing on site and remote scientific and technical services to the scientific community of the public and private sector. EMBRC successfully completed a preparatory phase in early in 2014 with the production of a business plan and a memorandum of understanding (MoU) signed by 9 countries. A host for its headquarters has been chosen and and an ERIC application is in preparation. Since only institutions from 5 MoU signatory countries went through the preparatory phase, the present proposal has as objectives: 1) to harmonize the access mechanism to the operational EMBRC-ERIC across all the partners, putting all the practical tools in place, including host contracts and single point online access platform, to enable EMBRC-ERIC to commence its access program; 2) to put in place practical guidelines towards the full implementation of the new European and international legislation and commitments on access and fair benefit sharing of the use of marine biological resources, thus providing clarity to future users of EMBRC-ERIC about their legal rights over obtained biological resources, and positioning itself globally as a broker between users and the supplying countries ; 3) to focus the smart specialization of the regions onto the opportunities marine biological resources offer for blue-biotech development and innovation, thus demonstrating the member states that EMBRC is a tool towards economic development of their maritime regions, and enticing them to sign the EMBRC-ERIC, and prioritize its sustained support, particularly from regions which are now underrepresented in EMBRC (Black and Baltic Seas). These activities will ensure that the beneficiary research communities can exploit the results obtained at EMBRC-ERIC facility from the start with the highest efficiency.

Agency: European Commission | Branch: H2020 | Program: RIA | Phase: INFRADEV-4-2014-2015 | Award Amount: 9.04M | Year: 2015

Marine (blue) biotechnology is the key to unlocking the huge economic potential of the unique biodiversity of marine organisms. This potential remains largely underexploited due to lack of connectivity between research services, practical and cultural difficulties in connecting science with industry, and high fragmentation of regional research, development and innovation (RDI) policies. To overcome these barriers, EMBRIC (European Marine Biological Resource Infrastructure Cluster) will link biological and social science research infrastructures (EMBRC, MIRRI, EU-OPENSCREEN, ELIXIR, AQUAEXCEL, RISIS) and will build inter-connectivity along three dimensions: science, industry and regions. The objectives of EMBRIC are to: (1) develop integrated workflows of high quality services for access to biological, analytical and data resources, and deploy common underpinning technologies and practices; (2) strengthen the connection of science with industry by engaging companies and by federating technology transfer (TT) services; (3) defragment RDI policies and involve maritime regions with the construction of EMBRIC. Acceleration of the pace of scientific discovery and innovation from marine bioresources will be achieved through: (i) establishment of multidisciplinary service-oriented technological workflows; (ii) joint development activities focusing on bioprospection for novel marine natural products, and marker-assisted selection in aquaculture; (iii) training and knowledge transfer; (iv) pilot transnational access to cluster facilities and services. EMBRIC will also connect TT officers from contrasted maritime regions to promote greater cohesion in TT practices. It will engage with policy-makers with the aim of consolidating a perennial pan-European virtual infrastructure cluster rooted in the maritime regions of Europe and underpinning the blue bioeconomy.

Agency: European Commission | Branch: FP7 | Program: CP-IP | Phase: OCEAN.2011-2 | Award Amount: 11.51M | Year: 2012

Micro B3 will develop innovative bioinformatic approaches and a legal framework to make large-scale data on marine viral, bacteria; archaeal and protists genomes and metagenomes accessible for marine ecosystems biology and to define new targets for biotechnological applications. Micro B3 will build upon a highly interdisciplinary consortium of 32 academic and industrial partners comprising world-leading experts in bioinformatics, computer science, biology, ecology, oceanography, bioprospecting and biotechnology, as well as legal aspects. Micro B3 is based on a strong user- and data basis from ongoing European sampling campaigns to long-term ecological research sites. For the first time a strong link between oceanographic and molecular microbial research will be established to integrate global marine data with research on microbial biodiversity and functions. The Micro B3 Information System will provide innovative open source software for data-processing, -integration, -visualisation, and -accessibility. Interoperability will be the key for seamless data transfer of sequence and contextual data to public repositories. Micro B3 will allow taking full advantage of current sequencing technologies to efficiently exploit large-scale sequence data in an environmental context. Micro B3 will create integrated knowledge to inform marine ecosystems biology and modelling. Moreover, it will facilitate detecting candidate genes to be explored by targeted laboratory experiments for biotechnology and for assigning potential functions to unknown genes. Micro B3 will develop clear IP agreements for the protection and sustainable use of pre-competitive microbial genetic resources and their exploitation in high potential commercial applications. To underline the translational character of Micro B3, outreach and training activities for diverse stakeholders are planned as well as an Ocean Sampling Day to transparently make project results accessible and gain valuable user feedback.

Agency: European Commission | Branch: H2020 | Program: RIA | Phase: INFRADEV-4-2014-2015 | Award Amount: 15.00M | Year: 2015

ENVRIPLUS is a cluster of research infrastructures (RIs) for Environmental and Earth System sciences, built around ESFRI roadmap and associating leading e-infrastructures and Integrating Activities together with technical specialist partners. ENVRIPLUS is driven by 3 overarching goals: 1) favoring cross-fertilization between infrastructures, 2) implementing innovative concepts and devices across RIs, and 3) facilitating research and innovation in the field of environment to an increasing number of users outside the RIs. ENVRIPLUS organizes its activities along a main strategic plan where sharing multi-disciplinary expertise will be most effective. It aims to improve Earth observation monitoring systems and strategies, including actions towards harmonization and innovation, to generate common solutions to many shared information technology and data related challenges, to harmonize policies for access and provide strategies for knowledge transfer amongst RIs. ENVRIPLUS develops guidelines to enhance trans-disciplinary use of data and data-products supported by applied use-cases involving RIs from different domains. ENVRIPLUS coordinates actions to improve communication and cooperation, addressing Environmental RIs at all levels, from management to end-users, implementing RI-staff exchange programs, generating material for RI personnel, and proposing common strategic developments and actions for enhancing services to users and evaluating the socio-economic impacts. ENVRIPLUS is expected to facilitate structuration and improve quality of services offered both within single RIs and at pan-RI level. It promotes efficient and multi-disciplinary research offering new opportunities to users, new tools to RI managers and new communication strategies for environmental RI communities. The produced solutions, services and other project results are made available to all environmental RI initiatives, thus contributing to the development of a consistent European RI ecosystem.

Cunliffe M.,Marine Biological Association of The United Kingdom
ISME Journal | Year: 2011

The Marine Roseobacter Clade (MRC) is a numerically and biogeochemically significant component of the bacterioplankton. Annotation of multiple MRC genomes has revealed that an abundance of carbon monoxide dehydrogenase (CODH) cox genes are present, subsequently implying a role for the MRC in marine CO cycling. The cox genes fall into two distinct forms based on sequence analysis of the coxL gene; forms I and II. The two forms are unevenly distributed across the MRC genomes. Most (18/29) of the MRC genomes contain only the putative form II coxL gene. Only 10 of the 29 MRC genomes analysed have both the putative form II and the definitive form I coxL. None have only the form I coxL. Genes previously shown to be required for post-translational maturation of the form I CODH enzyme are absent from the MRC genomes containing only form II. Subsequent analyses of a subset of nine MRC strains revealed that only MRC strains with both coxL forms are able to oxidise CO. © 2011 International Society for Microbial Ecology All rights reserved.

Smale D.A.,Marine Biological Association of The United Kingdom
Proceedings. Biological sciences / The Royal Society | Year: 2013

Species distributions have shifted in response to global warming in all major ecosystems on the Earth. Despite cogent evidence for these changes, the underlying mechanisms are poorly understood and currently imply gradual shifts. Yet there is an increasing appreciation of the role of discrete events in driving ecological change. We show how a marine heat wave (HW) eliminated a prominent habitat-forming seaweed, Scytothalia dorycarpa, at its warm distribution limit, causing a range contraction of approximately 100 km (approx. 5% of its global distribution). Seawater temperatures during the HW exceeded the seaweed's physiological threshold and caused extirpation of marginal populations, which are unlikely to recover owing to life-history traits and oceanographic processes. Scytothalia dorycarpa is an important canopy-forming seaweed in temperate Australia, and loss of the species at its range edge has caused structural changes at the community level and is likely to have ecosystem-level implications. We show that extreme warming events, which are increasing in magnitude and frequency, can force step-wise changes in species distributions in marine ecosystems. As such, return times of these events have major implications for projections of species distributions and ecosystem structure, which have typically been based on gradual warming trends.

Agency: European Commission | Branch: H2020 | Program: ERC-ADG | Phase: ERC-ADG-2014 | Award Amount: 2.70M | Year: 2015

SEACELLS addresses fundamental questions in phytoplankton biology from cellular to population scales. Our recent studies of phytoplankton, primitive photosynthetic marine protists that play important roles in ocean biogeochemical cycles, are providing exciting new information on the roles and evolution of membrane transport, cell signalling and metabolic regulation. The research builds on a number of recent findings, including the discovery of cell membrane properties that were thought to be typical of animal cells but now must be considered to be of much more ancient origin. The proposed 5-year programme brings together single cell biophysics, imaging and state of the art molecular biology with in situ studies of natural oceanic phytoplankton populations, focussing principally on two significant groups, the diatoms and coccolithophores. A major aim is to gain critical mechanistic understanding of membrane transport, cellular regulation and key physiological processes at the single cell level along with information on the microenvironment that surrounds cells. This will be used in conjunction with modelling studies to determine how phytoplankton cells regulate their immediate environment and how this in turn interacts with metabolic activity. In order to understand how the physiological properties of single cells in the laboratory translate to behaviour of natural populations we will examine cell physiological properties in natural populations. Knowledge of cell- to-cell variability will provide insights into the plasticity of populations and their responses to changing ocean conditions. Underpinning this is the transfer of single cell technology developed in the laboratory to ship-board platforms. SEACELLS presents a discipline-spanning approach, providing opportunities for cross-fertilization of knowledge and ideas from molecular biology through cell biophysics to in situ oceanography with wide reaching outcomes.

Agency: European Commission | Branch: FP7 | Program: CP-TP | Phase: KBBE.2013.3.2-02 | Award Amount: 10.08M | Year: 2013

The D-Factory aims to set a world benchmark for a sustainable biorefinery based on biomass from halophilic microalgae. Representing the largest (100s ha) of current commercial cultivation technologies for any microalga, Dunaliella microalgal biomass production uses raceways and lakes, and will be expanded with biorefinery concepts by drawing in European innovations in key biomass processing technologies: supercritical CO2; high performance counter-current chromatography; and the use of membranes, to produce carotenes and other bioactive compounds, emulsifiers and polymers. Combining this force with world-renowned expertise in the biochemistry of Dunaliella (Ben-Amotz) we will tailor the productivities of strains sourced by the Marine Biological Association for biorefinery requirements and add to the mix, experience in constructing and using the two most advanced systems for cultivating microalgae: a series of photobioreactors developed by A4F Portugal - currently scaled-up to the largest size in the world, 1.100 m3, and open raceways by NBT Israel - 10 ha in operation for \ 30 years. Novel harvesting technology will be developed based on spiral plate technology and ultramembrane filtration. Within 36 months we will be ready to showcase a sustainable D-Factory demonstration in Europe. Designs, flowsheets and integrated schemes along with sustainability assessments (technological, environmental, economic and social) will produce benchmarks for a wide range of products and paths. These will be used in the D-Factory business case developed by Hafren Investments to raise investment for the first prototype D-Factory in Europe. The D-Factory demonstration is scheduled to be operational in 48 months. It will reach stakeholders across the globe via an Innovation Platform and will serve as a robust manifestation for the business case for global investment in algae biorefineries and in large-scale production of microalgae using photobioreactors, algal raceways and lakes.

Agency: European Commission | Branch: FP7 | Program: CP-TP | Phase: KBBE.2012.3.5-01 | Award Amount: 12.44M | Year: 2013

KillSpill delivers innovative (bio)technologies, which can be integrated to the real sequences of state-of-the-art actions used currently to cleanup oil spills. The catalogue of KillSpill products & technologies is based on a review of technology & knowledge gaps in approaches of oil spill disasters and brings appropriate tools for 1st response, follow-up, and longer-term actions, specifically tailored to the versatility of oil spills. KillSpill develops chemicals & biochemicals to be used for 1st response actions to disperse/emulsify oil and materials enabling the containment and sorption of oil, preparing the field for the follow-up actions. KillSpill develops (Bio)technologies aiming at intensified biodegradation processes by bioaugmentation/biostimulation as follow-up and longer term actions in aerobic/slight anoxic compartments. KillSpill develops (bio)technologies adapted for the remediation of anoxic/anaerobic fresh & chronically polluted sediments. KillSpill compiles knowledge on dispersion/sorption and biodegradation processes to produce multifunctional products, which are suited for follow-up and longer term actions. The multifunctional products address the necessity for integrated bioremediation (bioavailability, metabolic requirements, etc.) and are efficient along the whole redox gradient from surface water to sediments. The products/technologies are field-tested in open sea oil spills and large mesocosms to unravel the champions products & technologies. The (bio)tools are benchmarked with existing solutions using cutting-edge analytics, biosensors, and omics and checked for eco-efficiency to merit green label. KillSpill consortium is multidisciplinary and gathers 33 partners from 12 EU and EU-associated countries and USA; 18 research & academic institutions, 14 SMEs, and 1 association of oil spill companies work together with the support of a high level advisory board to cover the whole chain of oil spill (bio)remediation.

Agency: European Commission | Branch: H2020 | Program: CSA | Phase: BG-13-2014 | Award Amount: 3.49M | Year: 2015

The overarching goals of the Sea Change project are to bring about a fundamental Sea Change in the way European citizens view their relationship with the sea, by empowering them as Ocean Literate citizens - to take direct and sustainable action towards healthy seas and ocean, healthy communities and ultimately - a healthy planet. Key objectives of Sea Change are to: Compile an in-depth review of the links between Seas and Ocean and Human health based on latest research knowledge outputs Build upon the latest social research on citizen and stakeholder attitudes, perceptions and values to help design and implement successful mobilisation activities focused on education, community, governance actors and directly targeted at citizens. marine education Build upon significant work to date, adopting best practice and embedding Ocean Literacy across established strategic initiatives and networks in order to help maximise impact and ensure sustainability Ensure that efforts to sustain an Ocean Literate society in Europe continue beyond the life of Sea Change through codes of good practice, public campaigns and other ongoing community activities. Ensure that all activities of Sea Change are carefully monitored and evaluated to ensure maximum sustainability, effectiveness and efficiency Ensure Knowledge exchange with transatlantic partners to bring about a global approach to protecting the planets shared seas and ocean. The objectives will be achieved by a closely interlinked programme. Sea Change includes a mobilisation phase engaging with citizens, formal education and policy actors. Crucially the legacy of Sea Change, including continuing knowledge sharing with North America, are embedded within the project.

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