Maranatha Christian University was founded on September 11, 1965 by the Christian scientific community in Bandung with the support of the Indonesia Christian Church and Pasundan Christian Church by the effort of the medical students of the Immanuel Christian Indonesian University. The university used to include only two faculties which were the Faculty of Medicine and the Faculty of Psychology. Wikipedia.
Tjahjani S.,Maranatha Christian University
BMC complementary and alternative medicine | Year: 2017
BACKGROUND: Malaria especially falciparum malaria still causes high morbidity and mortality in tropical countries. Several factors have been linked to this situation and the most important one is the rapid spread of parasite resistance to the currently available antimalarials, including artemisinin. Artemisinin is the main component of the currently recommended antimalarial, artemisinin based combination therapy (ACT), and it is a free radical generating antimalarial. Garcinia mangostana L (mangosteen) rind contain a lot of xanthone compounds acting as an antioxidant and exhibited antimalarial activity. The aim of this study was to evaluate the antimalarial activity of mangosteen rind extract and its fractions and their interaction with artemisinin against the 3D7 clone of Plasmodium falciparum in vitro.METHODS: Dry ripe mangosteen rind was extracted with ethanol followed by fractionation with hexane, ethylacetate, buthanol, and water consecutively to get ethanol extract, hexane, athylacetate, buthanol, and water fractions. Each of these substances was diluted in DMSO and examined for antimalarial activity either singly or in combination with artemisinin in vitro against Plasmodium falciparum 3D7 clone. Synergism between these substances with artemisinin was evaluated according to certain formula to get the sum of fractional inhibitory concentration 50 (∑FIC50).RESULTS: Analysis of the parasite growth in vitro indicated that IC50 of these mangosteen rind extract, hexane, ethylacetate, buthanol, and water fraction ranged from 0.41 to > 100 μg/mL. All of the ∑FIC50 were <1.CONCLUSIONS: This study demonstrated a promising antimalarial activity of the extract and fractions of G.mangostana L rind and its synergistic effect with artemisinin. Further study using lead compound(s) isolated from extract and fractions should be performed to identify more accurately their mechanism of antimalarial activities.
Ratnawati H.,Maranatha Christian University |
Widowati W.,Maranatha Christian University
Sains Malaysiana | Year: 2011
Hypercholesterolemia is the main risk factor of atherosclerosis which is directly related to coronary heart disease. Velvet bean (Mucuna pruriens L.) is predicted to have potential anticholesterolemia since a previous study showed that this plant had high antioxidant activity. The purpose of this research was to determine the anticholesterol activity of crude extract and ethyl acetate fraction of velvet bean compared to simvastatin and vitamin E in decreasing the plasma level of total cholesterol LDL and triglyceride and increasing the HDL level on hypercholesterolemic rats. Thirty male Wistar rats were divided into ten groups. Group I was fed with standard diet as negative control group and all the other groups were fed with high-fat diet and were given fructose solution. High-fat diet and fructose solution increased the level of total cholesterol LDL-cholesterol and triglyceride and decreased the level of HDL-cholesterol significantly compared to the negative control group. The treatment groups were given 3 various doses of crude extract (50, 100, 200 mg/kgBW) and ethyl acetate fraction ( 15, 30, 60 mg/kgBW) of velvet bean, simvastatin 2.7 mg/kgBW and vitamin E 60 mg/kgBW daily for ten days. The data were analyzed by one way Analysis of Variance ( ANOVA) and Duncan 's Post Hoc Test. The best results were shown by 15 mg/kgBW of ethyl acetate fraction in decreasing total cholesterol and 60 mg/kgBW of ethyl-acetate fraction for the LDL-chole sterol, 200 mg/kgBW of crude extract in increasing HDL-cholesterol and 50 and 200 mg/kgBW of crude extract and 60 mg of ethyl acetate fraction in lowering the triglyceride.
Karnalim O.,Maranatha Christian University
Proceedings - 2016 International Conference on Advanced Computing and Applications, ACOMP 2016 | Year: 2016
Despite the fact that keyphrase is widely used as a brief summary to represent documents, most keyphrase extraction is only focused on arbitrary text. However, many document types have specific behavior which require particular pre-processing in order to extract keyphrases. In software domain, keyphrases can only be extracted by utilizing reverse-engineering approach and applying several conversion rules. This paper proposes a mechanism to extract software keyphrases with domain-specific features. For our case study, our proposed method is applied to Java Archive, a distributional form of Java binaries. Besides pre-processing and conversion rules, our method also utilizes the combination of supervised and unsupervised keyphrase extraction approach to exploit the benefits of both approaches. Furthermore, in order to extract keyphrase pattern more accurately, software-related features are also incorporated besides standard keyphrase extraction features. These features are software structure, software-related natural language text, and software term association. Based on overall evaluation, our proposed method yields moderate R-precision. Thus, our approach is quite considerable to be applied for extracting software keyphrase. © 2016 IEEE.
Soenarko B.,Maranatha Christian University |
Setiadikarunia D.,Maranatha Christian University
Journal of Physics: Conference Series | Year: 2016
A half space problem in acoustics is described by introducing an infinite plane boundary that reflects the wave coming into the plane. A numerical solution using Boundary Element Method (BEM) has been known which is formulated using a modified Green's function in the Helmholtz Integral Formulation, which eliminates the discretization over the infinite plane. Hence, the discretization are confined to the body or obstacle in question only. This feature constitutes the main advantage of the BEM formulation for half space problems. However, no general analytical solution is available to verify the BEM results for half space problems. This paper is aimed to propose an analytical solution for the BEM to compare with, hence to verify the BEM calculation. This analytical approach is currently developed for a half space problem involving radiation and scattering of acoustic waves from a rigid sphere. The image of sphere as well as the image of the field point are defined with respect to the infinite plane. Then, an ad hoc solution is assumed involving a constant and the distance from the center of the sphere to the field point and the distance from the center of the image of the sphere to the field point. The constant is determined by imposing the boundary conditions. Test cases were run with several configuration involving the location of field points and the sphere. Comparison of the analytical solution with BEM calculations shows a good agreement between the two results.. © Published under licence by IOP Publishing Ltd.
Lesmana C.,Maranatha Christian University |
Suhendi S.,Maranatha Christian University
IOP Conference Series: Earth and Environmental Science | Year: 2017
This paper presents an investigation of connection performance for a simple supported prefabricated timber beams using Meranti hardwood (Shorea sp.). The good connection is crucial for the proper functioning of the timber structures. The adequate connection condition should be assured to achieve the requirement capacity design and performance of the system. The property of material was tested according to . The proposed design of bolted connections has been evaluated through experimental investigation and compared to the simple supported beam without connection. The results demonstrate the effectiveness of the proposed connection design although the ultimate load of the beam with connection is only half of the beam without connection. The test results obtained the purposed connection should be improved. © Published under licence by IOP Publishing Ltd.
Pasaribu N.T.B.,Maranatha Christian University |
Hasugian M.J.,Maranatha Christian University
Proceedings - 2016 3rd International Conference on Information Technology, Computer, and Electrical Engineering, ICITACEE 2016 | Year: 2017
This paper proposes the use of Artificial Neural Network (ANN) to remove background noise of Batak Toba handwritten script. Several artificial backgrounds are fused with the original script to reconstruct visual perception of manuscript text background. Experiments have been conducted on offline handwritten script cleaning process and show superior impact compared to threshold method and Gaussian filter. This is a seminal work on ancient Batak Toba manuscript recognition system as the primary research theme. © 2016 IEEE.
Karnalim O.,Maranatha Christian University
Proceedings of 2016 International Conference on Information and Communication Technology and Systems, ICTS 2016 | Year: 2017
Even though there are various source code plagiarism detection approaches, most of them only concern with low-level plagiarism attack with an assumption that plagiarism is only conducted by students who are not proficient in programming. However, plagiarism is often conducted not only due to student incapability, but also because of bad time management. Thus, high-level plagiarism attack should be detected and evaluated. This paper proposes source code plagiarism detection approach which can detect most introductory-programming-course plagiarism attacks at any level by utilizing low-level instructions instead of source code tokens. Several mechanisms are also introduced to improve its effectiveness such as instruction generalization, instruction reinterpretation, method-based comparison, and method linearization. Since low-level instruction is a language-dependent feature, Java is selected as target programming language with bytecode as its low-level instruction. Based on evaluation, it can be concluded that our approach is more effective to detect most plagiarism attack types than raw source code approach on introductory programming course. This evaluation is based on plagiarism attack types that are collected through controlled experiment. © 2016 IEEE.
Kasih J.,Maranatha Christian University |
Susanto S.,Parahyangan Catholic University
World Transactions on Engineering and Technology Education | Year: 2012
As an academic advisor, a full-time lecturer has the duty to help students in setting up their study plan each semester so that they can perform with maximum efficiency. The aim of this research is to ascertain which subjects determine the students' final passing results. An academic advisor is expected to be able to predict the students' final passing results. In order to achieve this goal, discriminant analysis can be applied for this purpose. This particular analysis, based on students' results obtained in several subjects was applied in this research, and is outlined and presented as an example in this article. © 2012 WIETE.
Darmayanti T.E.,Maranatha Christian University
MATEC Web of Conferences | Year: 2016
Sundanese are the largest indigenous ethnic group in the western part of Java Island. Sundanese culture closely relates to Animist, Hindu-Buddhist, and Islam philosophies. It led to the unique creation of the Sundanese traditional houses called Rumah Adat in Kampung Naga where the ancient tradition from their ancestor were upheld until today. Kampung Naga was listed as one of the Sundanese traditional villages known as Kampung Adat in West Java. This village has its own characteristics which enable the conveyance of tremendous tradition from the past, since the reign of Padjajaran Kingdom to the present. Additionally, it has the ability to accelerate globalization of culture these days. The objectives of this paper are to reintroduce and observe the in-depth meaning of Sundanese traditional houses within Kampung Naga. This paper employed qualitative investigation with the support of exploratory literature review. The result of this study portrayed that Sundanese traditional village are depicted as sacred spaces when the founder, the belief, and the nature spirit are interrelated. Thus, the creation of traditional houses in Kampung Naga does not only serve as shelters, but it also has "breath", "soul" and may embody cosmological value. This paper is prominent in the documentation of Sundanese traditional buildings as one of cultural identity of Indonesia, which will deliver the cultural knowledge to the world wide. © 2016 The Authors.
Rahardjo Emanuel A.W.,Maranatha Christian University
Proceedings - 2014 6th International Conference on Information Technology and Electrical Engineering: Leveraging Research and Technology Through University-Industry Collaboration, ICITEE 2014 | Year: 2015
Open Source Software (OSS) becomes one of the mainstream software development methodology competing with commercial and proprietary software development. One of the distinct characteristics of OSS projects is the existence group of contributors who joined the project voluntarily called OSS Communities. In this study, the statistical analysis of 263 popular OSS Projects and their communities is performed. The popularity of the OSS Projects is determined from suggestion from selected websites found from Google search engine. The analysis covers information such as OSS Project's name, description, category, repository, community type, number of contributors, and the start year. There are four important findings of the statistical analysis. First finding is that most of the category of the OSS Projects is computer and networking related. The other findings are that most of the project is in Ad Hoc state and the different trends in the number of contributors in Foundation and Commercial Company of OSS Communities. The last finding is that most of the OSS Projects are using Github, Sourceforge and Ohloh as their source code repositories. These results provide important insights about the structure and activities of OSS Projects and their communities. © 2014 IEEE.