Manchester, United Kingdom

Manchester Metropolitan University

www.mmu.ac.uk
Manchester, United Kingdom

Manchester Metropolitan University, often referred to as 'MMU' and simply referred to as 'Man Met', is a British public university located in North West England, and was established in 1970 as 'Manchester Polytechnic', and gained University Status in 1992. Its headquarters and central campus are in the city of Manchester, and there are additional facilities in the county of Cheshire. The university has its roots in the Manchester Mechanics' Institution and the Manchester School of Design . It is the fifth largest university in the United Kingdom in terms of student numbers.Teaching quality inspections place the university within the top twenty in the UK, according to The Complete University Guide. Teaching standards have also been described as 'among the highest in the country' by the Quality Assurance Agency. The university is ranked fourth of the new universities in attracting research funds from the Higher Education Funding Council for England.The university is an accredited member of the Association of MBAs, a member of the University Alliance, the Association of Commonwealth Universities, the North West Universities Association and the European University Association. The university is home to the Manchester School of Art, the Manchester School of Theatre and, in conjunction with the University of Manchester, the Manchester School of Architecture. Wikipedia.


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Patent
Manchester Metropolitan University | Date: 2014-02-11

A method of manufacturing an artificial eye for fitting as a whole or partial replacement of a patients original eye. This is done by providing an image of an iris on a substrate (100, 300) comprising at least a frontal region of an artificial eye, providing a support (108, 308) for the substrate, positioning the substrate and support in a mould (122, 322), and encapsulating the substrate within a mould material (136, 336).


Grant
Agency: European Commission | Branch: H2020 | Program: IA | Phase: SCC-01-2014 | Award Amount: 29.50M | Year: 2015

The Triangulum project will demonstrate how a systems innovation approach based around the European Commissions SCC Strategic Implementation Plan can drive dynamic smart city development. We will test the SIP across three lighthouse cities: Manchester, Eindhoven and Stavanger, which represent the main typologies of European cities. They will be complemented by our follower cities Prague, Leipzig and Sabadell. This powerful combination reflects an urban population of between 100k and 1,2m inhabitants across six different countries, allowing us to demonstrate successful replication across a wide range of typical urban areas in Europe. Each city has already made significant progress towards the transition of becoming a smart city; developing their own individual approach reflecting specific local circumstances. These inherent strengths will now serve to accelerate the smart city development across proposed demonstration sites within Triangulum. The suite of projects developed will be based around zero/low energy districts, integrated infrastructures and sustainable urban mobility designed to deliver a range of cross-cutting outcomes across different sectors and stakeholders. This will provide the basis to road test the SIP and provide recommendations to the Commission on how it could be improved to facilitate wider replication. The Triangulum goals target a series of direct impacts around; reduced energy consumption of buildings, increased use of renewable energies, increased utilisation of electric vehicles, deployment of intelligent energy management technologies and the deployment of an adaptive and dynamic ICT data hub. The design and implementation of innovative Business Models and the activation of citizens as co-creators are core cross-cutting elements to base the technologies in real-world city environments and facilitate replication.


Grant
Agency: European Commission | Branch: H2020 | Program: RIA | Phase: PHC-22-2015 | Award Amount: 6.87M | Year: 2016

Mental, cognitive, vision and hearing health problems in elderly people are amongst the top 10 public health challenges in Europe. They frequently occur co-concurrently and have an additive negative effect on quality of life and mental well-being. To address this negative impact, and promote mental well-being, particularly from a gender and minority community perspective, SENSE-Cogs aim is to: (1) understand the inter-relationship of sensory impairments and cognitive and mental health functioning; (2) identify novel means of screening/detection for diagnostic and therapeutic purposes; and (3) translate this knowledge into clinical applications for the mental well-being of EU citizens. Methods: SENSE-Cog will use a mixed methods approach with a trans-EU, UK-led, multidisciplinary collaboration of 7 EU countries with academics, SMEs, city government and patient-public voice members. We will deliver linked Work Packages (WPs) reflecting 7 themes: (1) exploration: an epidemiological analysis of 5 large EU longitudinal databases to detect risk profiles for good and poor mental health outcomes; (2) assessment: the adaptation/validation of assessment tools for cognition and sensory impairment for vulnerable populations, including the development of a composite e-screen for sensory, cognitive and mental functioning; (3) intervention: a clinical trial of a newly developed sensory support intervention; (4) participation: an EU patient and public voice and innovative public engagement network to inform the WPs and communicate findings; (5) valuation: health economic and cost effectiveness analyses; & (6) management, governance/ethics. Impact: SENSE-Cog will promote earlier detection of sensory, cognitive and mental impairments to enable swift interventions, prevent deterioration and limit negative impacts.


Grant
Agency: European Commission | Branch: H2020 | Program: IA | Phase: IoT-01-2016 | Award Amount: 20.05M | Year: 2017

SynchroniCity represents the first attempt to deliver a Single Digital City Market for Europe by piloting its foundations at scale in 11 reference zones - 8 European cities & 3 more worldwide cities - connecting 34 partners from 11 countries over 4 continents. Building upon a mature European knowledge base derived from initiatives such as OASC, FIWARE, FIRE, EIP-SCC, and including partners with leading roles in standardization bodies, e.g. ITU, ETSI, IEEE, OMA, IETF, SynchroniCity will deliver a harmonized ecosystem for IoT-enabled smart city solutions where IoT device manufacturers, system integrators and solution providers can innovate and openly compete. With an already emerging foundation, SynchroniCity will establish a reference architecture for the envisioned IoT-enabled city market place with identified interoperability points and interfaces and data models for different verticals. This will include tools for co-creation & integration of legacy platforms & IoT devices for urban services and enablers for data discovery, access and licensing lowering the barriers for participation on the market. SynchroniCity will pilot these foundations in the reference zones together with a set of citizen-centred services in three high-impact areas, showing the value to cities, businesses and citizens involved, linked directly to the global market. With a running start, SynchroniCity will serve as lighthouse initiative to inspire others to join the established ecosystem and contribute to the emerging market place. SynchroniCity takes an inclusive approach to grow the ecosystem by inviting businesses and cities to join through an open call, allowing them to participate on the pioneering market place enabling a second wave of successful pilots. They will strengthen the ecosystem by creating a positive ripple effect throughout Europe, and globally, to establish a momentum and critical mass for a strong European presence in a global digital single market of IoT-enabled solutions.


Grant
Agency: European Commission | Branch: H2020 | Program: RIA | Phase: PHC-14-2015 | Award Amount: 6.00M | Year: 2016

The goal of BATCure is to advance the development of new therapeutic options for a group of rare lysosomal diseases - neuronal ceroid lipofuscinoses (NCL) or Batten disease. There are > thousand affected across Europe, with a combined incidence of c.1:100 000. The NCLs are devastating and debilitating genetic disorders that mainly affect children, who suffer progressive dementia and motor decline, visual failure and epilepsy, leading to a long period of complete dependence on others, and eventually a premature death. Existing palliative treatment can reduce, but does not eliminate, the burden of seizures and the progressively worsening effects on the whole body due to decreasing CNS influence and control. There are no curative treatments in the clinic for any type of NCL. We will follow a novel integrated strategy to identify specific gene and small molecule treatments for three genetic types of Batten disease that include the most prevalent world-wide, juvenile CLN3 disease, and in southern and mediterranean Europe, CLN6 and CLN7 diseases. To develop new therapies for these 3 types of Batten disease, BATCure will: 1. Create new models, tools and technologies for developing and testing therapies 2. Further delineate disease biology and gene function to identify new therapeutic target pathways utilising yeast and pluripotent stem cell models 3. Identify biochemical therapeutic target pathways, facilitate effective evaluation of preclinical therapies and improve diagnostics 4. Extend a comprehensive natural history beyond the brain to include cardiology, the spinal cord, PNS, psychiatric and metabolic changes 5. Identify new and repurpose existing small molecule therapy 6. Triage new compound treatments in zebrafish, a high-throughput small vertebrate model 7. Deliver and monitor new treatments using mouse models 8. Provide a novel mechanism to involve patients and their families to inform and fully contribute to therapy development and prepare for clinical trials


Valtchev V.,National Engineering School of Caen | Tosheva L.,Manchester Metropolitan University
Chemical Reviews | Year: 2013

The steady interest in nanosized porous solids is due to the potential of these materials to offer sustainable solutions to global issues such as increasing energy demands and at the same time more rigorous environmental standards for industrial pollutants, depletion of resources, and health improvement. Considering the accumulated number of publications dedicated to porous nanoparticles and their somewhat limited outreach in cross-disciplinary fields, the aim of this review is to provide an overview of recent developments in the area of synthesis and applications of the different groups of porous nanomaterials. The classical definition of a zeolite is a crystalline aluminosilicate built of oxygen-linked tetrahedral silicon and aluminum atoms that form a three-dimensional microporous structure comprising channels and voids occupied by alkali or alkali-earth cations and water molecules.


Grant
Agency: European Commission | Branch: H2020 | Program: RIA | Phase: BES-05-2015 | Award Amount: 4.50M | Year: 2016

iCROSS envisages to enable faster thorough border control for third country nationals crossing the borders of EU, with technologies that adopt the future development of the Schengen Border Management. The project will present an optimal mixture of an enhanced, voluntary form of a Registered Traveller Programme and an auxiliary solution for the Entry/Exit System based on involving bona fide travellers. iCROSS designs and implements a system that adopts mobility concepts and consists of a two-stage procedure, designed to reduce cost/time spent per traveller at the crossing station. It leverages software and hardware technologies ranging from portable readers/scanners, various emerging and novel subsystems for automatic controls, wireless networking for mobile controls, and secure backend storage and processing. The two-stage procedure includes: (A) the registration before the travel to gather initial personal, travel document and vehicle data, perform a short, automated, non-invasive interview with an avatar, subject to lie detection and link the traveller to any pre-existing authority data. Utilizing multifactor analytics and risk-based approach, the data registered is processed and correlated with publicly open data or external systems such as the SIS II. Processing will need the travellers consent as set in EU legislation and national law. (B) the actual control at the border that complements pre-registered information with results of security controls that are performed with a portable, wireless connected iCROSS unit that can be used inside buses/trains or any point. Multiple technologies check validity and authenticity of parameters (e.g. travel documents, visa, face recognition of traveller using passport picture, real-time automated non-invasive lie detection in interview by officer, etc.). The data collected are encrypted, securely transferred and analysed in real time, providing an automated decision support system for the border control officers.


Grant
Agency: European Commission | Branch: H2020 | Program: CSA | Phase: ISSI-5-2015 | Award Amount: 2.36M | Year: 2016

The goal of the project is to foster RRI transition in Europe by developing and testing good RRI practices in pilot cases, for a further upscaling among the RTOs in the EU28. A Responsible Research and Innovation (RRI) Plan will be developed and implemented at the biggest European RTOs, the Fraunhofer-Gesellschaft and TNO, covering the five RRI key dimensions (societal engagement, gender equality and gender in research and innovation con-tent, open access, science education and ethics). After identifying the state-of-the-art of good RRI practices, goals will be developed for within each dimension. Barriers for the achievement of these goals will be analyzed, and an action plan to overcome these barriers will be formulated. The project will be set up as a mutual learning process between the consortium, further European RTOs, stakeholders, and two international associated partners.


Grant
Agency: European Commission | Branch: H2020 | Program: MSCA-ITN-ETN | Phase: MSCA-ITN-2016 | Award Amount: 3.56M | Year: 2017

This proposal sprang from European scientists in both academia and industry who identified a common challenge: setting up a training frame to educate the next generation of imagers in complex biological systems (healthy & pathological), so they are able to master all major aspects of this competitive field and bring important innovations to universities and companies. The long-term goal of any initiative to image biological processes is reaching cellular or subcellular resolution in a complete organism. This is now possible using vertebrate embryos as models and the most recent technological advances as tools. ESRs will be trained by addressing the following scientific bottlenecks and challenges: -Preparing vertebrate embryos (rodent & zebrafish) for optimal imaging -Fine-tuning sensors, reporters and actuators to track cell types, cellular processes and behaviours in living organisms -Developing and implementing new imaging instruments -Analysing complex sets of big-data images to extract relevant information -Using processed images to design computational and mathematical models of development and pathologies -Comparing these models with experimental data and create a feedback loop improving the whole work chain from sample preparation to instrumentation and analysis. This interdisciplinary training is based on an intersectoral organisation of the consortium with partners from academia and companies that need these future experts to develop new instruments, screen drugs and chemicals in living systems and develop software to analyse and model medical images. The full training programme is based on an optimal balance between training through research and many network-wide training events, including conferences with physical presence, digital conferences and monthly videolink events. Consortium members are keen to implement both classical and original outreach activities (eg MOOCs, serious games, Lego designs) to bring state-of-the-art microscopy to the classroom.

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