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PubMed | MAMC, All India Institute of Medical Sciences and DDU Hospital
Type: | Journal: Journal of forensic sciences | Year: 2016

In an air-conditioning system, the compressor is a large electric pump that pressurizes the refrigerant gas as part of the process of turning it back into a liquid. The explosion of an air conditioner (AC) compressor is an uncommon event, and immediate death resulted from the blast effect is not reported in forensic literature. We report three such cases in which young AC mechanics were killed on the spot due to compressor blast, while repairing the domestic split AC unit. The autopsy findings, the circumstances leading to the explosion of the compressor, are discussed in this study.


Sethi P.,Dr S N Medical College | Mohammed S.,Dr S N Medical College | Bhatia P.K.,Dr S N Medical College | Bhatia P.K.,All India Institute of Medical Sciences | And 2 more authors.
Indian Journal of Anaesthesia | Year: 2014

Background: Traditionally, midazolam has been used for providing conscious sedation in endoscopic retrograde cholangiopancreatography (ERCP). Recently, dexmedetomidine has been tried, but very little evidence exists to support its use. Objective: The primary objective was to compare haemodynamic, respiratory and recovery profile of both drugs. Secondary objective was to compare the degree of comfort experienced by patients and the usefulness of the drug to endoscopist. Study Design: Open-label Randomised Controlled Trial. Methods: Subjects between 18 and 60 years of age with American Society of Anaesthesiologist Grade I-II requiring ERCP were enrolled in two groups (30 each). Both groups received fentanyl 1 μg/kg IV at the beginning of ERCP. Group M received IV midazolam (0.04 mg/kg) and additional 0.5 mg doses until Ramsay Sedation Scale (RSS) score reached 3-4. Group D received dexmedetomidine at loading dose of 1 μg/kg over 10 min followed by 0.5 μg/kg/h infusion until RSS reached 3-4. The vital parameters (heart rate (HR), blood pressure (BP), respiration rate, SpO2), time to achieve RSS 3-4 and facial pain score (FPS) were compared during and after the procedure. In the recovery room, time to reach modified Aldrete score (MAS) 9-10 and patient and surgeon's satisfaction scores was also recorded and compared. Any complication during or after the procedure were also noted. Results: In Group D, patients had lower HR and FPS at 5, 10 and 15 min following the initiation of sedation (P<0.05). There was no statistically significant difference in BP and respiratory rate. The procedure elicited a gag response in 29 (97%) and 7 (23%) subjects in Group M and Group D respectively (P<0.05). MAS of 9-10 at 5 min during recovery was achieved in 27 (90%) subjects in Group D in contrast to 5 (17%) in Group M (P<0.05). Dexmedetomidine showed higher patient and surgeon satisfaction scores (P<0.05). Conclusion: Dexmedetomidine can be a superior alternative to midazolam for conscious sedation in ERCP.


Sharma H.,Institute of Medical science | Khare G.N.,Institute of Medical science | Singh S.,Institute of Medical science | Ramaswamy A.G.,SMIMS | And 2 more authors.
Journal of Orthopaedic Science | Year: 2014

Objectives: Management of AO type B and C fractures of the distal radius is controversial. This study compares outcomes and complications of AO type B and C fractures of the distal radius treated with volar locked plating and nonoperative methods. Materials and methods: Sixty-four patients with fractures of the distal radius (AO type B and C) were included in this study, according to inclusion criteria, and were allocated to the volar plating group or nonoperative group by alternate randomization: 32 patients with odd numbers went into the nonoperative group and the other 32 with even numbers went into the volar plating group. Patients in the nonoperative group were managed with closed reduction of the fracture and plaster cast application under an image intensifier. Those in the volar plating group were managed by open reduction and fixation with a volar locked plate. Preoperative and postoperative serial clinico-radiological follow-up was done. The range of movement, grip strength, functional outcome scores and radiological parameters were compared. Student's t-test was used for statistical analysis with significance at p < 0.05. Results: Range of movement and functional scores were significantly (p < 0.001) better in the volar plating group, but the difference in ulnar variance and radial and ulnar deviation was insignificant as compared to the nonoperative group. At 24 months follow-up, the nonoperative group had significantly more cases with malunion, articular incongruity and osteoarthritis. Conclusion: In cases of AO type B or C fractures of the distal radius, volar locked plating provides anatomical stable fixation and early mobilization with better clinico-radiological outcome as compared to conservative treatment. © 2014 The Japanese Orthopaedic Association.


Ghalaut V.S.,Pt. B.D.Sharma PGIMS | Sangwan L.,Pt. B.D.Sharma PGIMS | Dahiya K.,Pt. B.D.Sharma PGIMS | Ghalaut P.S.,Pt. B.D.Sharma PGIMS | And 2 more authors.
Journal of Oncology Pharmacy Practice | Year: 2012

Nitric oxide (NO) is involved in different stages of malignancies. Increased levels of NO have been reported in different leukemias. Imatinib is the preferred drug for the treatment of chronic myeloid leukemia (CML). Turmeric powder contains curcumin which has anti-leukemic property and also decreases NO synthesis. This study was conducted on fifty patients of CML divided into two groups, group A receiving imatinib alone and group B receiving turmeric powder along with imatinib for six weeks. Nitric oxide levels were estimated in these patients before and after receiving therapy and were analyzed statistically. Nitric oxide levels were found to be significantly decreased in both the groups, but more significantly in group B after receiving the respective treatments. Thus, curcumin acts as an adjuvant to imatinib in decreasing the NO levels and may help in the treatment of CML patients. © The Author(s) 2011.


Goyal V.,Ggs Medical College | Goyal P.K.,M.A.M.C. | Gupta M.,Ggs Medical College
Journal of Clinical and Diagnostic Research | Year: 2014

A trichobezoar is a mass of culminated hair within the gastrointestinal tract. Stomach is the common site of occurrence. Intestinal obstruction due to primary trichobezoar is extremely rare. Only few cases have been reported so far. We also present a case of 13-year-old girl having primary ileal trichobezoar causing intestinal obstruction.


Bhawna S.,Hemwati Nandan Bahuguna Garhwal University | Bharti A.,MAMC | Yogesh K.,Hemwati Nandan Bahuguna Garhwal University | Reena A.,Swami Dayanand Hospital
Iranian Journal of Pathology | Year: 2013

Background& Objectives: In spite of intensive worldwide efforts to reduce its transmission, malaria remains the most serious and widespread protozoal infection of humans. This study has been performed to evaluate various hematological alterations in patients infected with malaria and to add more detailed information, especially from these highly affected zones. Materials and Methods: A two-year, hospital-based study was conducted and hematologic profiles of 200 persons infected with malaria (Plasmodium vivax or P. falciparum) infection were examined and the results were compared with standard normal values. Results: One-hundred-ninety-six patients were infected with P. vivax, three with P. falciparum, and one with both. Patients with parasitemia tended to have significantly lower platelets, hemoglobin, white blood cell and red blood cell counts, blood indices and hematocrit than normal. Thrombocytopenia is identified as a key indicator of malaria in these febrile patients. Conclusion: Anemia and thrombocytopenia are the classical changes. Changes in the white blood cells are less dramatic, may vary due to variable size and type of cases, variability of the species, and geographical differences.


Behera C.,MAMC
Journal of Indian Academy of Forensic Medicine | Year: 2012

A 42 year old male, was found hanging by a plastic rope in his unbolted bed room. The rope was found attached to two suspension points (one end attached to the window panel and the other side to the ceiling knob) and the middle part of it used for the binding of neck. There was no knot present in the ligature as the right hand was found holding the ligature loop for the purpose of constriction of neck. A towel was found covering the head and underneath the ligature material on the neck used for padding. Blood stain was present on the floor below the suspended body which oozed out from the haemorrhoids. He was holding the cloth, wore in lower half of the body up to the mid thigh label, which appreciated by the authors as cadaveric spasm that developed in his flexor muscles of left hand. Detailed autopsy, crime scene examination and police investigation supported the manner of death as suicidal.


Aggarwal A.,MAMC | Sharma K.R.,MAMC | Verma U.C.,MAMC
Journal of Anesthesia and Clinical Research | Year: 2012

Background: Preoperative evaluation of anatomical landmarks and clinical factors help identify potentially difficult airway. Till date there are no criteria or absolute guidelines that can be helpful in detecting difficult airway in pediatric population. Aim: To find the predictors of difficult mask ventilation difficult laryngoscopy and difficult intubation in pediatric population age 1-5 years. Setting and design a prospective study was conducted in 100 ASA grade I/II pediatric patients between 1-5 years, scheduled for surgery under general anesthesia. Patients with congenital upper airway malformations and those with neck or face swelling or scars were excluded from the study. Material and methods: We assessed the usefulness of interincisor gap (IIG), oropharyngeal view with mouth wide open (without tongue protrusion), modified mallampati Class (MMP), relationship of maxillary and mandibular incisor during normal jaw closure, neck circumference(NC), thyromental distance (TMD), sternomental distance (SMD), ratio of height to thyromental distance as preoperative predictors of difficult mask ventilation, laryngoscopy and intubation. Result: Mask ventilation was graded using difficult mask ventilation (DMV) grading, with DMV grade of 3 & 4 occurring in 3 patients (3%). Laryngoscopy was assessed using Cormack and Lehane (C&L) grading system which revealed 3 cases of CL grade III with no case falling under CL grade IV. Ease or difficulty in tracheal intubation was assessed using Intubation difficulty score (IDS) 40% cases showed mild difficulty (05) and 2% showed major difficulty (IDS>5). Conclusion: Interincisor gap, neck cicumferance, sternomental distance was found to be predictors of difficult mask ventilation. Statistically significant correlation was found between difficult laryngoscopy and intubation. Age, best oropharangeal view and thyromental distance were found to be predictors of difficult larngoscopy and intubation. Analysis proved that mask ventilation became easier after administration of muscle relaxant and difficulty decreased after 3 years age. © 2012 Aggarwal A, et al.


Saraf S.K.,Banaras Hindu University | Kumaraswamy V.,MAMC
Indian Journal of Orthopaedics | Year: 2013

In vivo studies using the animals are helpful in developing the treatment strategies as they are important link between the successful in vitro testing and safe human use. Various research projects in the field of fixation of fractures, development of newer biomaterials, chemotherapeutic drugs, use of stem cells in nonunion of fractures and cartilage defects etc., have hugely depended on animal experimentation. The employment of animals in experiments is both scientific and ethical issue. There must be reasonable reasons to show that it will significantly advance the present knowledge and lead to improvement in care. The regulatory bodies exist for humane use and care of animals used for experiments e.g., International Council for Laboratory Animal Science, Council for International Organizations of Medical Sciences, International Union of Biological Sciences, International Committee on Laboratory Animals. In India, Indian National Science Academy, Indian Council of Medical Research, National Centre for Laboratory Animal Sciences promote high standards of laboratory animal quality, care and health. The Committee for the Purpose of Control and Supervision on Experiments on Animals guidelines are well defined and is a must read document for any one interested to carry out research with animal facilities.


PubMed | MAMC
Type: | Journal: Oral and maxillofacial surgery | Year: 2016

Spontaneous herniation of temporomandibular joint into the external auditory canal through the foramen of Huschke is a very rare condition. We describe a case of spontaneous temporomandibular joint herniation in a 35-year-old male, who presented with otorrhea and aural fullness. The herniation was repaired using collagen mesh. A literature review of all the previous reported cases of spontaneous temporomandibular joint was done to study the presenting clinical features and the method of surgical repair.

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