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PubMed | Dr Hedgewar Smruti Runga Seva Mandals Dental College And Hospital, Mamata Dental College and Hospital, Kiran Dental Hospital, AIMST University and HKDE Trusts Dental College and Hospital
Type: Journal Article | Journal: Journal of lasers in medical sciences | Year: 2016

Oral premalignant lesions are conditions having high potential tendency for transformation into malignancy. The use of a conservative and effective treatment modality is one of the best strategies for cancer prevention. Photodynamic therapy (PDT) is a non-invasive method for topical and selective treatment of oral precancerous lesions. The present study was taken up to determine the efficacy of PDT in oral precancerous lesions.The study consisted 13 patients with 24 oral leukoplakia (OL) lesions and 8 with 20 oral lichen planus (OLP) lesions, divided into control and study groups. These lesions were affecting various intraoral sites, the buccal mucosa being the most common site followed by tongue and gingiva. The treatment regimen of PDT included 98% 5-aminolevulinic acid (5-ALA) which is topical applied and irradiated with light emitting diode (LED) of 420 nm wavelengths at several sessions.In OL 16.6% of cases showed complete response, 66.6% partial response and 16.6% no response of the lesions to the treatment. In OLP 80% and 20% of the lesions showed partial and no response respectively. The differences with control groups for OL + OLP were found to be significant (P < 0.001).Based on the results of the present study, we can conclude that PDT appears to be a feasible alternative to conventional therapy for oral premalignant lesions.


PubMed | Teerthankar Mahaveer Dental College and Hospital, Chhattisgarh Dental College & Research Institute, Sb Patil Dental College, Azamgarh Dental College and 2 more.
Type: Journal Article | Journal: Journal of international oral health : JIOH | Year: 2015

Probiotics are defined as live microorganisms which when taken in adequate amounts provide a health benefit on the host. They have been used to improve gastrointestinal health, and their popularity has prompted increased interest for their role in the promotion of oral health also. The study was undertaken to evaluate the influence of diet alteration on oral microflora with the addition of probiotics in the form of curd in the diet.Sample pool included total 20 children, 15 in experimental group; who were given curd containing probiotic bacteria in their diet daily and 5 children in control group; who were contradicted of food containing probiotics. All the children were followed for over a period of 1-year. A pre and post quantitative analysis of Streptococcus mutans and Lactobacilli were done in the saliva of both active and control groups, and caries score was recorded.The data thus compiled were statistically evaluated using Chi-square test and Pearson correlation on SPSS software version 14.In experimental group, 87% children showed decrease and 7% showed increase in S. mutans count (P = 0.83), whereas 67% showed increase and 7% decrease in Lactobacilli count (P = 0.002) after 1-year of follow-up.Probiotics are upcoming as an intriguing field in oral health. Efforts should be made to increase the knowledge of the general dental practitioners with this facet of oral disease therapy and promote the implementation of the concept of food rather than medicine.


PubMed | Mamata Dental College and Hospital
Type: Journal Article | Journal: Journal of clinical and diagnostic research : JCDR | Year: 2015

Oral Lichen planus (OLP) is a common mucocutaneous disorder with a multifactorial aetiology, affecting the women more commonly than men. Most OLP are asymptomatic, except the atrophic and erosive forms.Till date many treatment modalities are implicated to treat this disorder, but no therapy is considered as the single most effective, without side-effects and remission of the lesion. As the treatment of OLP is challenging to the oral practitioners, here we report a case of successful management of extensive, symptomatic bullous and erosive oral lichen planus with a novel treatment protocol- oral minipulse therapy with betamethasone.


Saraf K.,SMBT Dental College and Hospital | Shashikanth M.C.,UP Dental College and Hospital | Priya T.,Mamata Dental College | Sultana N.,MIDSR Dental College and Hospital | Chaitanya N.C.S.K.,Mamata Dental College and Hospital
Journal of Association of Physicians of India | Year: 2010

Probiotics are dietary supplements containing potentially beneficial bacteria or yeasts. They are administered in different quantities that allow for colon colonization. These products help in stimulating health promoting flora and also suppressing the pathologic colonization and disease spread. The use of probiotic plays an important aspect in dentistry too ever since the oral infections occupied the prime space among the other infections effecting the humans. This concept of microbial ecologic change both for medical and dental changes has accumulated a lot of evidence in recent times. But to date, no substantial literature and use has been postulated. There are claims that probiotics strengthen the immune system to combat allergies, stress, exposure to toxic substances and other diseases. There are reports of their beneficial use in HIV infection and cancers, mostly, the colo-rectal carcinomas. Their use in pre malignant and malignant oral disorders is yet to be probed. Strains of genera lactobacillus and bifidobacterium are the most widely used probiotic bacteria. This review is an attempt to discuss briefly the role of probiotics in medicine and dentistry. © JAPI.


Beeram R.K.,Mamata Dental College and Hospital | Seelam S.,Mamata Dental College and Hospital
Journal of Oral and Maxillofacial Surgery, Medicine, and Pathology | Year: 2016

Cystic angiomatosis is a rare vascular disorder, characterized by multifocal hemangiomatous and/or lymphangiomatous lesions of the skeleton with possible visceral organ involvement. The aim of the present communication is to report a unique case of massive craniofacial skeletal cystic angiomatosis in a 15-year-old boy with history of progressive enlargement of all craniofacial bones since birth associated with severe anemia secondary to splenomegaly. The computed tomography and magnetic resonance imaging techniques revealed hypertrophy of the craniofacial skeleton secondary to multiple cystic lesions and also disclosed cystic lesions in cervical, lumbar, sacral vertebrae and the spleen. Histologically, it was analogous to cavernous hemangioma. This was an unusual case of classical bilateral, craniofacial skeletal angiomatosis; till date a total of three cases have been reported but the present case was diverse from the reported ones. © 2015 Asian AOMS, ASOMP, JSOP, JSOMS, JSOM, and JAMI.


Beeram R.K.,Mamata Dental College and Hospital | Seelam S.,Mamata Dental College and Hospital | Prasad L.K.,SIBAR Institution of Dental science
Journal of Oral and Maxillofacial Surgery, Medicine, and Pathology | Year: 2016

Objective: Selection of the method of intubation during complex facial surgeries is a difficult task for the anesthetist because of airway is sharing area and oral or nasal intubation is not preferable, even though, tracheostomy is a worthy alternative; however, it has serious complications. Altemir FH introduced the 'submental technique' as a substitute for tracheostomy but it has demonstrated the complications of 'lingual nerve damage' and 'Wharton's duct injuries'. So, the Stoll's approach is the safest option in this scenario. The purpose of the present study was to evaluate 'Stoll's submandibular method' as a safest choice to Altemir's technique. Materials and method: The study was conducted prospectively in a sample of 42 patients for intra-operative airway management in complex facial surgeries during the period of six years from 2008 to 13 by considering the following objectives: duration of the procedure, and intra-operative and postoperative complications. Results: The average time taken for this procedure was 9 min. The complications encountered were superficial skin wound infection in a total of three patients (7%), partial extubation in one case (2%), cuff leakage in one case (2%) and dislodgement of the tube in one case (2%). Conclusion: The results of the present study have provided the evidence of Stoll's technique as a safest choice both for Altemir's and tracheostomy in justifiable circumstances because of simple, quick technique associated with negligible complications. So, anesthetist should consider this underutilized technique in complex facial surgeries and it is a valuable option in patients, who underwent tracheostomy in previous surgeries. © 2015 Asian AOMS, ASOMP, JSOP, JSOMS, JSOM, and JAMI.


Kanthem R.K.,Mamata Dental College and Hospital | Guttikonda V.R.,Mamata Dental College and Hospital
Journal of Oral and Maxillofacial Pathology | Year: 2015

Background: Lipids play a key role in the maintenance of cell integrity. These are major cell membrane components essential for various biological functions, including cell growth and division of normal and malignant tissues. Abnormal changes have long been associated with alterations in lipid profile. Aim: The aim of this study was to evaluate the alterations in lipid profile in oral submucous fibrosis (OSMF) patients and to compare the levels with respect to the clinical staging and histological grading. Materials and Methods: Fifty patients of OSMF, diagnosed clinically and histopathologically, were included as the study subjects. A group of 50 age and sex matched normal subjects without any oral pernicious habits were taken as controls. The serum lipid profile consisting of total cholesterol (TC), triglycerides (TGs), high density lipoprotein (HDL), very low density lipoprotein (VLDL) and low density lipoprotein (LDL) were analyzed using Erba Chem-5 Plus Analyzer. Results: Serum TC, HDL and LDL levels were significantly decreased in OSMF patients as compared to controls. As the clinical stage progresses, the TC and HDL levels were gradually reduced. All the lipid profile parameters such as TC, TG, HDL, VLDL and LDL progressively reduced as the histological grade advanced. Conclusion: The results of the present study showed that there is an inverse relationship between lipid profile and the presence of OSMF. The decreased serum lipid profile may be considered as a useful indicator for initial changes occurring in the cells of potentially malignant disorders like OSMF. © 2015 Journal of Oral and Maxillofacial Pathology.


PubMed | Mamata Dental College and Hospital
Type: Journal Article | Journal: Indian dermatology online journal | Year: 2016

Cowdens syndrome is an autosomal dominant genodermatosis with variable orofacial and systemic manifestations. Here we present one such classical case of Cowdens syndrome in a 45-year-old female patient with features such as multiple cutaneous papillomatosis, oral fibromas, and fibromas involving multiple organs such as gastrointestinal tract (multiple polyps), thyroid disorders, and breast cancer.


PubMed | Mamata Dental College and Hospital and Gayatri Dental Hospital
Type: Journal Article | Journal: Journal of maxillofacial and oral surgery | Year: 2016

ZMC fractures are the common facial injuries. The main causes of fractures are trauma due to RTAs, assaults, falls, sports related injuries, and the civilian warfares. This study is to evaluate and review the etiology, incidence, clinical findings and treatment of ZMC fractures. A sincere effort has been put forward in the management of ZMC fractures and their efficacy is evaluated in the larger interest of the patients.In this study 101 patients having displaced ZMC fractures with insignificant medical history were reviewed to evaluate the versatility of its management, with the main emphasis on post operative stability, restoration of mouth opening, wound healing, esthetic restoration of the prominence of cheek and the complications encountered.A total of 101 patients were reviewed for the management of ZMC fractures. All the cases included were managed during the period from August 2007 to August 2009 in the Department of Oral and Maxillofacial Surgery, Mamata Dental College and Hospital, Khammam. The extremes of ages in this study ranged from 17 to 60years with the mean of 43. RTA was the most common cause of injury. Seventy-eight patients (77%) were managed with surgical treatment.Attention should be paid to improvement in automobile safety devices and compliance by motor vehicle occupants in addition to the improvement of the rules and regulations in sporting activities.


PubMed | Mamata Dental College and Hospital
Type: Journal Article | Journal: Craniomaxillofacial trauma & reconstruction | Year: 2015

Incidence and etiology of facial fractures vary from region to region due to various constituents. This study was carried to evaluate the patterns and distribution of fractures in the facial region among different age groups of patients in both males and females caused due to various etiologies. This is a retrospective epidemiological study, which was performed on patients with fractures in the maxillofacial region during a period of 2005 to 2013 at Mamata Dental College and Hospital, Khammam, India. A total of 1,015 patients with 1,545 fractures were referred for treatment to department of oral and maxillofacial injuries surgery, of Mamata Dental College and Hospital, with a mean age of 31.19. The ratio of males (859):females (156) is 5.5:1. Injuries caused by motorbike injuries (34.9%) are highest. The highest frequency of fractures caused by various reasons is seen more in third decade (39%). Mandible (43.81%) is the most common fracture site in the face. Among soft tissue injuries most commonly seen are lacerations (43%). This study differentiates the etiological factors causing facial trauma in several age groups. Results of this study suggest outcomes indicate that more reliance on individual transport on motor vehicles has increased the frequency of facial bone fractures. Regardless of age, motor vehicle accidents were high in all age groups except the first decade of life and above 60 years of age when traffic accidents dominated. Thus effectiveness of current preventive measures is to be assessed, followed by instituting new guidelines for prevention and inflexible traffic rules shall be levied. More epidemiological surveys can, if encouraged to measure the frequency of fractures, better the world.

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