Mallareddy Institute of Medical science

science, India

Mallareddy Institute of Medical science

science, India
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Hima Bindu M.,Mallareddy Institute of Medical science | Hima Bindu M.,Saveetha University | Kapur I.,Mallareddy Institute of Medical science | Vijayaraghavan R.,Saveetha University
Biomedical Research (India) | Year: 2017

Background: Titanium (Ti) and Ti alloys are known to have good mechanical properties with high corrosion resistance and excellent biocompatibility. Doping of silver ions onto a titanium dioxide based surface resulted in the movement of the absorption to a longer wavelength due to a change in the electronic and optical properties of TiO2 and thereby increasing the antibacterial effect. Aim: This work was done to investigate the effectivity of nanoparticles of TiO2 doped with 0.3% wt of silver prepared by sol-gel technique, as an anti-bacterial agent against Pseudomonas aeruginosa from clinical samples. Materials and methods: TiO2 with 0.3% silver as additive was systematically assessed on 25 Pseudomonas aeruginosa isolates from various clinical samples and incubated in dark, in visible light and under UV radiation for the antibacterial effect. After each hour of incubation, the isolates were inoculated onto Mueller Hinton agar. Results: The viable colonies diminished within 2 h of incubation under UV irradiation, while under visible light, the number of viable colonies was highly reduced after 3 h. Under dark, the reduction was considerably slower, taking 6 h, while in all the light conditions the control, which had no exposure to nanoparticles, showed no reduction in the number of colonies. Conclusion: TiO2 with Ag as an additive is highly effective as an antibacterial agent on many human pathogens including Pseudomonas aeruginosa, which is notorious in causing hospital acquired infections. TiO2 with 0.3 wt (%) Ag is most effective under UV irradiation and least in dark. © 2017, Scientific Publishers of India. All rights reserved.


Dambal A.,BIMS | Nimbal N.,BIMS | Patil G.,BIMS | Padaki S.,GIMS | And 3 more authors.
Journal of Clinical and Diagnostic Research | Year: 2015

Introduction: Assessment of cardiovascular cases in practical exit exam is limited to simple history taking and physical examination. Standards of assessment are not uniform. This makes assessment less valid and reliable. Aim: To explore the perceptions of Internees and General Medicine Examiners about current practices in Cardio Vascular system (CVS) case presentation in final MBBS exit exams and the necessity to change some of the practices. Materials and Methods: A set questions pertaining to the preparation for exams, validity, reliability, feasibility and educational impact were prepared to guide in obtaining the perceptions of internees and internal medicine examiners. Focus group discussions were conducted. Data Analysis was done by immersion-crystallization process. Results: Most of the internees admitted to feeling concerned because of difficulty in diagnosing murmurs by auscultation. Most of the examiners felt concerned about the logistics involved in arranging practical exams. Both admitted to the lack of uniform standards in assessment. Both agreed that the present system thrived as it was relatively feasible. Some internees suggested that the exam may be conducted in two parts by splitting the syllabus instead of once. Some internees suggested incorporating a student-doctor program to improve practical skills just like the on-going student nurse program. Conclusion: There is a need for overhauling the assessment of cardiovascular system in final MBBS summative exams towards one aligned to the competencies as required in an Indian Medical Graduate. Blueprinting of practical assessment with due weightage assigned to epidemiologically important topics is the need of the hour. © 2015, Journal of Clinical and Diagnostic Research. All rights reserved.


Dambal A.,BIMS | Lakshmi K.S.,BIMS | Gorikhan G.,BIMS | Umadi M.M.,BIMS | And 4 more authors.
Journal of Clinical and Diagnostic Research | Year: 2015

Introduction: Acute kidney injury is a rare and sometimes fatal complication of pregnancy, the incidence of which has been declining worldwide, though still high in developing countries. There are recent observations of increasing incidence in some developed countries attributed to hypertensive disorders of pregnancy. Materials and Methods: In this study, we have analysed the records of all patients referred to the dialysis unit of a medical college hospital in Karnataka for acute kidney injury related to pregnancy. AKIN (Acute Kidney Injury Network) criteria for the diagnosis of acute kidney injury were adapted. Age, parity, gestational age, causative factors for acute kidney injury, mode of delivery, access to antenatal care, operative procedures, blood component transfusions, number of haemodialysis, time for initiation of haemodialysis, duration of hospital stay and mortality were analysed by finding mean, standard deviation and standard error. Results: Fifteen patients out of 21563 who delivered in our hospital developed acute kidney injury. These (n=15) were out of 149 patients of acute kidney injury of various aetiologies who underwent haemodialysis between 2012 and 2014. Of these two were unregistered for antenatal care. Ten were multiparous, Eleven were from rural background, one had home delivery, six had vaginal delivery, seven had caesarean section and two had second trimester abortion. Placental abruption with intrauterine death was the commonest Cause in 9 out of 15 cases. All had severe anaemia. Patients received a mean of 3.9 (SD+/- 2.4) sessions of haemodialysis. Eleven patients recovered completely, two died and two left against medical advice. Conclusion: Obstetric acute kidney injury is associated with poor access to antenatal care, multiparity and rural background. Placental abruption is the commonest cause of obstetric acute kidney injury. Blood component transfusions, avoidance of nephrotoxic drugs and early initiation of haemodialysis are associated with better outcome. © 2014, Journal of Clinical and Diagnostic Research. All rights reserved.


PubMed | Professor and Head, Mallareddy Institute of Medical science and Senior Resident
Type: Journal Article | Journal: Journal of clinical and diagnostic research : JCDR | Year: 2016

Assessment of cardiovascular cases in practical exit exam is limited to simple history taking and physical examination. Standards of assessment are not uniform. This makes assessment less valid and reliable.To explore the perceptions of Internees and General Medicine Examiners about current practices in Cardio Vascular system (CVS) case presentation in final MBBS exit exams and the necessity to change some of the practices.A set questions pertaining to the preparation for exams, validity, reliability, feasibility and educational impact were prepared to guide in obtaining the perceptions of internees and internal medicine examiners. Focus group discussions were conducted. Data Analysis was done by immersion-crystallization process.Most of the internees admitted to feeling concerned because of difficulty in diagnosing murmurs by auscultation. Most of the examiners felt concerned about the logistics involved in arranging practical exams. Both admitted to the lack of uniform standards in assessment. Both agreed that the present system thrived as it was relatively feasible. Some internees suggested that the exam may be conducted in two parts by splitting the syllabus instead of once. Some internees suggested incorporating a student-doctor program to improve practical skills just like the on-going student nurse program.There is a need for overhauling the assessment of cardiovascular system in final MBBS summative exams towards one aligned to the competencies as required in an Indian Medical Graduate. Blueprinting of practical assessment with due weightage assigned to epidemiologically important topics is the need of the hour.

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