Mallareddy Engineering College

Secunderabad, India

Mallareddy Engineering College

Secunderabad, India
SEARCH FILTERS
Time filter
Source Type

Samyuktha V.S.,Jawaharlal Nehru University | Subbarao T.,Sri Krishnadevaraya University | Suvarna R.P.,Jawaharlal Nehru University | Kumar A.G.,Mallareddy Engineering College
Journal of Ovonic Research | Year: 2017

The Calcium Doped Magnesium Titanate ceramic materials of different compositions were synthesized by conventional Solid-state diffusion method. The results of XRD and microstructure analysis showed that the specimens had crystalline, homogenous and dense structures. The dielectric constant from room temperature to 350°C was calculated using HIOKI 3532-50 LCR HiTESTER in the frequency range of 1KHz-1MHz.In the present investigation the dielectric response of Calcium doped Magnesium titanate was studied. It showed that the dielectric constant and dielectric loss were increased with temperature and decreased with frequency and also observed the enhancement of dielectric constant with the addition of small amount of Calcium to the Magnesium Titanate ceramics. The a.c. conductivity of the specimens were measured and thermoelectric properties were also studied. © 2017, Virtual Institute of Physics of the Foundation Horia Hulubei. All rights reserved.


Malladi S.,University of the Humanities | Malladi S.,Jawaharlal Nehru Technological University Anantapur | Ratnakaram V.N.,Gandhi Institute of Technology and Management | Babu K S.,Mallareddy Engineering College | Pullaiah T.,SKD University
Oriental Journal of Chemistry | Year: 2017

Phytochemical screening of Caralluma lasiantha was carried out and one C21 pregnane steroid was isolated from chloroform extract. Based on spectroscopic studies (IR, 1H NMR, 13C NMR and ESI-MS) the isolated compound is 3β,14β-dihydroxy-14β-pregn-5-en-20-one which was earlier isolated from other species. © 2017, Oriental Scientific Publishing Company. All rights reserved.


Srinivasarao Ch.,Koneru Lakshmaiah College of Engineering | Asadi S.S.,Koneru Lakshmaiah College of Engineering | Kameswararao M.,Mallareddy Engineering College
International Journal of Civil Engineering and Technology | Year: 2017

Natural sand deposits are being used up and causing serious threat to environment as well as the society. Traditionally, river sand has been the main source of supply but the restrictions now imposed by the Green Tribunal because of environmental degradation causing so many problems like losing water retaining soil strata, deepening of the riverbed sand causing bank slides, loss of vegetation on the bank of rivers, disturbs the aquatic life as well as disturb agriculture due to lowering the water table in the well etc. are some of the examples. Several studies have been conducted concerning the protection of natural resources, prevention of environmental pollution and contribution to the economy by using these industrial byproducts. The pollution effect on the environment can be reduced by increasing the usage of industrial byproducts in our construction industry. This paper focus on investigating behavior of M60 Grade Portland slag cement (PSC) concrete by fully and partial replacement of fine aggregate by Granulated Blast Furnace Slag (GBFS). Cubes, cylinders and beams are tested for compressive, split tensile and flexural strength after 7 and 28, days curing. Replacement percentage of fine aggregate by GBFS are 30, 50, 80 and 100 percent respectively. Water cement ratio used in this work is 0.32 and slump to be obtained 100mm. Based on the test results it is recommended GBFS can be replaced 100% against crushed sand and river sand in high grade concretes(M60) by using mineral admixtures(silica fume). As per the experiment, the desired slump of 100 mm is achieved by adjusting the dosage of Chemical ad mix(PCE Based). © IAEME Publication.


Geetha Swarupa P.,Koneru Lakshmaiah College of Engineering | Radha Krishna D.,Mallareddy Engineering College | Prasad K.R.S.,Koneru Lakshmaiah College of Engineering | Suresh Babu K.,Mallareddy Engineering College
Der Pharmacia Lettre | Year: 2015

The purpose of the investigation was to develop a new RP-HPLC Method for estimation of Aprepitant in pharmaceutical dosage forms. Chromatography was carried out on an Kromosil C18 column (4.6 x 250mm, 5μ particle size) with a isocratic mobile phase composed of 0.1% Perchloric acid, Acetonitrile (80:20v/v) at a flow rate of 1.1 mL/min. The column temperature was maintained at 30°C and the detection was carried out using a PDA detector at 210 nm. Validation parameters such as system suitability, linearity, precision, accuracy, specificity, limit of detection (LOD), limit of quantification (LOQ), Stability of sample and standard stock solutions and robustness were studied as reported in the International Conference on Harmonization guidelines. The retention time for Aprepitant was 3.429 min. The percentage recovery of Aprepitant was 101.01%. The relative standard deviation for assay of capsule was found to be less than 2%. The Method was fast, accurate, precise and sensitive hence it can be employed for routine quality control of capsules containing drugs in quality control laboratories and pharmaceutical industries.


Srikanth K.V.V.,Koneru Lakshmaiah College of Engineering | Prasad K.R.S.,Koneru Lakshmaiah College of Engineering | Shanmukha Kumar J.V.,Koneru Lakshmaiah College of Engineering | Suresh Babu K.,Mallareddy Engineering College
Der Pharmacia Lettre | Year: 2015

Simple rapid,accurate and stability indicating HPLC method is described for the quantification of Pramipexole in bulk drug. Chromatographic quantification of Pramipexole is achieved on Xterra RP 18 column using isocratic Mobile phase of Sodium dodecyl sulphate, ethyl acetate,2-propanol and 0.2% Triflouroacetic acid in water (33:66:1:900,w/w) at a flow rate of 1.0mL/min with injection volume10μL. Column temperature was maintained at 30°C .The proposed method was validated for system suitability, linearity, precision, specificity, stability, Limit of Detection and Limit of quantification. Degradation studies were conducted as per ICH guidelines. Limit of Detection and Limit of Quantification of Pramipexole were 2.96μg/mL and 6.85μg/mL respectively. The proposed method can be used for routine analysis and stability studies.


Prasad P.S.R.,CSIR - Central Electrochemical Research Institute | Chari V.D.,Mallareddy Engineering College
Journal of Natural Gas Science and Engineering | Year: 2015

The release of methane gas was compared in pure CH4 (sI) and mixed (sII) hydrates (with C4H8O - tetrahydrofuran and C3H8 - propane) having methane as dominant constituent. We report absence of the self preservation effect in mixed hydrates, having stiochiometric composition (sII) of larger guest molecules, and they populate the 51264 cages. Their dissociation behaviour is in accordance with the respective phase boundary curve. While a partial methane gas release was observed at 270K, particularly, in dilute systems. Further, excess gas release was at T>270K and complete methane release is governed by the thermodynamic stability of mixed hydrates. © 2015.


Swarupa P.G.,Koneru Lakshmaiah College of Engineering | Krishna D.R.,Mallareddy Engineering College | Prasad K.R.S.,Koneru Lakshmaiah College of Engineering | Babu K.S.,Mallareddy Engineering College
Oriental Journal of Chemistry | Year: 2015

The purpose of the investigation was to develop a new RP-HPLC Method for estimation of Rotigotine in pharmaceutical dosage forms. Chromatography was carried out on an BDS C-8 column (4.6 × 150mm, 5μ particle size) with a isocratic mobile phase composed of 0.01N Potassium dihydrogen Ortho phosphate (adjusted to pH 4.8 with OPA solution), Acetonitrile (45:55v/v) at a flow rate of 1 mL/min. The column temperature was maintained at 30°C and the detection was carried out using a PDA detector at 224 nm. Validation parameters such as system suitability, linearity, precision, accuracy, specificity, limit of detection (LOD), limit of quantification (LOQ), Stability of sample and standard stock solutions and robustness were studied as reported in the International Conference on Harmonization guidelines. The retention time for Rotigotine was 2.691 min. The percentage recoverie of Rotigotine was 100.33%. The relative standard deviation for assay of patch was found to be less than 2%. The Method was fast, accurate, precise and sensitive hence it can be employed for routine quality control of patchs containing both drugs in quality control laboratories and pharmaceutical industries.


Geetha Swarupa P.,Koneru Lakshmaiah College of Engineering | Lakshmana Rao K.,Mallareddy Engineering College | Prasad K.R.S.,Koneru Lakshmaiah College of Engineering | Suresh Babu K.,Mallareddy Engineering College
Asian Journal of Pharmaceutical and Clinical Research | Year: 2016

Objective: To develop accurate, fast, simple, and precise reversed-phase high-pressure liquid chromatography method for simultaneous determination of the binary mixture of metformin (MET) and empagliflozin (EMPA) in dosage forms. Methods: The method uses a mobile phase consisting of phosphate buffer, acetonitrile, methanol (15:80:5 v/v/v), an octadecyl silica C-18 column (4.6 mm × 250 mm, 5 μ particle size) in isocratic mode, detection wavelength of 227 nm, and a flow rate of 1 mL/minutes. Results: The measured retention times for MET and EMPA and were 2.528 and 4.140 minutes, respectively. The percentage recoveries of MET and EMPA were 101.12% and 100.55%, respectively. The relative standard deviation for assay of tablets was found to be <2%. The correlation coefficient for MET and EMPA was found to be 0.9990. The limit of detection and quantification for MET was 0.10 μg/mL and 0.31 μg/mL and for EMPA 0.01 μg/mL and 0.03 μg/mL. Conclusion: The method was fast, accurate, precise, and sensitive hence it can be employed for routine quality control of tablets containing both drugs in quality control laboratories and pharmaceutical industries. © 2016, Innovare Academics Sciences Pvt. Ltd. All rights reserved.

Loading Mallareddy Engineering College collaborators
Loading Mallareddy Engineering College collaborators