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Shibuya-ku, Japan

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Malcom & Co. Llc and San Simeon Inc. | Date: 2004-06-22

CLOTHING FOR WOMEN, AND CHILDREN, NAMELY, DRESSES, BLOUSES, TOPS, SKIRTS, PANTSUITS, SUITS, STOCKINGS, SHIRTS, JACKETS, SWEATERS, PANTS, FOOTWEAR, BELTS, T-SHIRTS, SOCKS, COORDINATED SHIRTS, JACKETS AND SLACKS, SWEAT SHIRTS, JERSEYS, SHORTS, JOGGING SUITS, SWEAT PANTS, HATS/CAPS, SCARVES, GLOVES, HOSIERY, NECKTIES, RAINWEAR, PAJAMAS, ROBES, AND NIGHT SHIRTS.


Otani Y.,Utsunomiya University | Kobayashi F.,Utsunomiya University | Mizutani Y.,Tokushima University | Watanabe S.,Malcom Co. | And 2 more authors.
Proceedings of SPIE - The International Society for Optical Engineering | Year: 2010

A uni-axial measurement of three dimensional surface profiles by a liquid crystal digital shifter is proposed using a telecentric optical system. Height information is captured by measuring the contrast in the projected pattern. A shadow less measurement of the object's area is archived by using a uni-axial system. The magnification of the object image captured by a CCD camera is made constant by changing the focus distance. The liquid crystal digital shifter is a powerful tool to make arbitrary intensity and frequency distribution. Surface profiles of mechanical parts were measured to demonstrate this method. © 2010 SPIE. Source


Saeki T.,Tokyo University of Agriculture and Technology | Sugamura Y.,Tokyo University of Agriculture and Technology | Hosokawa M.,Tokyo University of Agriculture and Technology | Yoshino T.,Tokyo University of Agriculture and Technology | And 4 more authors.
Biosensors and Bioelectronics | Year: 2014

This study presents a novel method for CD4 testing based on one-shot large-field imaging. The large-field imaging system was fabricated by a microcavity array and a two-dimensional (2D) photosensor within the desk-top-sized instrument. The microcavity array was employed to separate leukocytes from whole blood based on differences in the size of leukocytes and other blood cells. The large-field imaging system with lower side irradiation enabled acquisition of cell signatures with high signal-to-noise ratio, because the metallic substrate of the microcavity array obstructed excessive excitation light. In this setting, dual-color imaging of CD4+ and CD8+ T cells was achieved within the entire image area (64mm2) in 2s. The practical performance of the large-field imaging system was demonstrated by determining the CD4/CD8 ratio in a few microliter of control whole blood as small as those obtained by a finger prick. The CD4/CD8 ratios measured using the large-field imaging system correlated well with those measured by microscopic analysis. These results indicate that our proposed system provides a simple and rapid CD4 testing for the application of HIV/AIDS treatment. © 2014 Elsevier B.V. Source


Saeki T.,Tokyo University of Agriculture and Technology | Hosokawa M.,Tokyo University of Agriculture and Technology | Lim T.-K.,Malcom Co. | Harada M.,Malcom Co. | And 2 more authors.
PLoS ONE | Year: 2014

In this paper, we present a novel cell counting method accomplished using a single-cell array fabricated on an image sensor, complementary metal oxide semiconductor sensor. The single-cell array was constructed using a microcavity array, which can trap up to 7,500 single cells on microcavities periodically arranged on a plane metallic substrate via the application of a negative pressure. The proposed method for cell counting is based on shadow imaging, which uses a light diffraction pattern generated by the microcavity array and trapped cells. Under illumination, the cell-occupied microcavities are visualized as shadow patterns in an image recorded by the complementary metal oxide semiconductor sensor due to light attenuation. The cell count is determined by enumerating the uniform shadow patterns created from one-on-one relationships with single cells trapped on the microcavities in digital format. In the experiment, all cell counting processes including entrapment of non-labeled HeLa cells from suspensions on the array and image acquisition of a wide-field-of-view of 30 mm2 in 1/60 seconds were implemented in a single integrated device. As a result, the results from the digital cell counting had a linear relationship with those obtained from microscopic observation (r2 = 0.99). This platform could be used at extremely low cell concentrations, i.e., 25-15,000 cells/mL. Our proposed system provides a simple and rapid miniaturized cell counting device for routine laboratory use. © 2014 Saeki et al. Source

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