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Lucknow, India

Prasad G.V.R.,University of Delhi | Sahni A.,Mahatma Gandhi Marg
Special Paper of the Geological Society of America | Year: 2014

During the last two decades, extensive paleontological research in the main Deccan volcanic province has led to a better understanding of biodiversity close to the Cretaceous-Paleogene boundary. Several infratrappean localities exposed in Jabalpur, Kheda, Balasinor, Rahioli, Dohad, and Bagh in the Narmada Valley (India) preserve one of the most geographically widespread dinosaur nesting sites known in the world. The well-studied intertrappean beds, such as those of Naskal on the southern margin, Asifabad and Nagpur on the eastern margin, Kisalpuri and Mohgaon Kalan on the northeastern margin, and Anjar on the northwestern margin of the main Deccan volcanic province, have yielded Maastrichtian fish (Igdabatis) and dinosaur remains and palynofossils (Aquilapollenites-Gabonisporites-Ariadnaesporites), either separately or in association, that suggest a Maastrichtian age for these beds. Only two intertrappean sections, Papro on the northern margin and Jhilmili on the northeastern margin of the main Deccan volcanic province, have produced Paleocene fossils. The fossil record from the infratrappean and intertrappean beds demonstrates that the dinosaurs survived the early phase of volcanism, though there was an apparent decline in their diversity, and that freshwater vertebrate fauna was least affected by the initial volcanic activity. The episodic nature of Deccan volcanism may possibly explain the survival of many freshwater and terrestrial communities during the periods of quiescence. In addition, as in the case of the late Maastrichtian sections in eastern Montana, North America, detritus-feeding freshwater vertebrate communities possibly had greater potential for survival than the terrestrial communities dependent on primary productivity. A close examination of the vertebrate faunal distribution across the two stratigraphic intervals (infratrappean and intertrappean) suggests that sampling bias in the infratrappean beds may have also masked the actual diversity of these beds. © 2014 The Geological Society of America. All rights reserved. Source

Tripathi R.P.,Mahatma Gandhi Marg | Pandey J.,Mahatma Gandhi Marg | Kukshal V.,Mahatma Gandhi Institute | Ajay A.,Mahatma Gandhi Marg | And 6 more authors.
MedChemComm | Year: 2011

A series of dispiro-cycloalkanones were synthesized using the "Corey Chaykovsky" reaction of α,α′-(E,E)-bis(benzylidene)- cycloalkanones/methanone in good yields. The compounds were evaluated for their in vitro antituberculosis activity against M. tuberculosis H37Rv and screened in silico. Some selected compounds were screened for mycobacterial NAD +-dependent DNA ligase inhibitory activity. Two of the compounds showed good in vitro antitubercular and NAD+-dependent DNA ligase inhibitory activity along with good correlation to in silico results. © The Royal Society of Chemistry 2011. Source

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