Moka, Mauritius
Moka, Mauritius

Mahatma Gandhi Institute of Technology is a technological institution located in Gandipet, Hyderabad, Telangana, India.It was started in 1997 by the Chaitanya Bharathi Educational Society , Hyderabad, registered under the Societies Registration Act. The annual intake is 720 students in undergraduate level and 72 students in postgraduate level. The institute is affiliated to Jawaharlal Nehru Technological University, Hyderabad and offers the four-year Bachelor of Technology, in eight disciplines and two-year Master of Technology, in four disciplines prescribed by JNTU. The college is accredited by the National Board of Accreditation and is ISO 9001:2000 certified. Wikipedia.


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Dambhare D.G.,Mahatma Gandhi Institute
Global journal of health science | Year: 2012

The onset of menstruation is part of the maturation process. However, variability in menstrual cycle characteristics and menstrual disorders are common. The purpose of this study was to determine the age at menarche and patterns of menstruation among school adolescent girls and explore its variation across socio-economic and demographic factors. This is a cross-sectional descriptive study carried out on 1100 school adolescent girls in district Wardha, Central India. Data were collected using a self-administered structured questionnaire on menstruation. Data was entered and analyzed by using Epi Info 6.04 software package. Chi- square value was used for testing statistical significance. Mean ages of menarche were 13.51 + 1.04 years and 13.67 + 0.8 years for urban and rural areas respectively. Abnormal cycle length was common and affected 30.48%. The majority 56.15 experienced dysmenorrhoea and 56.16 percent had premenstrual syndrome. Self medication was practiced by 7.13% of the adolescent girls. The most common premenstrual symptom was headache 26.74%. Absenteeism from the school 13.9% was the effect of menstruation related problems on their daily routine. Dysmenorrhea and premenstrual symptoms were perceived as most distressing symptoms leading to school absenteeism. Majority of the girls 75.58% had discussed menstrual problems with someone, most commonly with their mothers 38.15%. There was a general lack of information about menstrual issues especially with regards to cycle length, duration of menses and age at menarche. Girls from families of high socio-economic class have significantly lower mean menarcheal age in both urban and rural area. The mean age of menarche was significantly higher in girls involved in vigorous sporting activity in urban area compared to their non-sporting counterparts. Age at menarche was delayed. The menstrual disorders among female adolescents are common. A school health education on menstrual problems targeting adolescent girls and their parents and routine screening for menstrual problems by healthcare providers can help to prevent the absenteeism in the school.


Jha K.N.,Mahatma Gandhi Institute
Journal of Clinical and Diagnostic Research | Year: 2014

Publications are essential for sharing knowledge, and career advancement. Writing a research paper is a challenge. Most graduate programmes in medicine do not offer hands-on training in writing and publishing in scientific journals. Beginners find the art and science of scientific writing a daunting task. ‘How to write a scientific paper?, Is there a sure way to successful publication ?’ are the frequently asked questions. This paper aims to answer these questions and guide a beginner through the process of planning, writing, and correction of manuscripts that attract the readers and satisfies the peer reviewers. A well-structured paper in lucid and correct language that is easy to read and edit, and strictly follows the instruction to the authors from the editors finds favour from the readers and avoids outright rejection. Making right choice of journal is a decision critical to acceptance. Perseverance through the peer review process is the road to successful publication. © 2014, Journal of Clinical and Diagnostic Research. All rights reserved.


Single-incision laparoscopic cholecystectomy (SILC) is considered to be less invasive and have less morbidity than conventional laparoscopic cholecystectomy (CLC). However, there is a relative paucity of data regarding postoperative pain scores in rural Indian populations following SILC. Also, data pertaining to the applicability of SILC in rural Indian population are scant. In the present randomized control trial, pain scores after SILC and CLC were evaluated. Sixty patients with gallstone disease were randomly assigned to one of two groups with 30 patients each: the CLC group and the SILC group. Postoperative pain scores were recorded on the visual analog scale at 8 hours, 24 hours and 7 days after surgery. The patients were comparable with respect to age, sex and BMI. Operative time was longer for the SILC group (47.73 ± 5.57 min vs 69.53 ± 8.96 min; P < 0.0001).The pain scores were similar in both groups at 8 hours (3.61 ± 0.41 vs 3.50 ± 0.51; P = 0.36) and 24 hours (3.30 ± 0.59 vs 3.20 ± 0.40; P = 0.44) postoperatively. On day 7, the SILC group had lower pain scores than the CLC group (2.56 ± 0.56 vs 1.16 ± 0.37; P < 0.01). There was no distinct advantage to SILC with regard to immediate postoperative pain. Pain was significantly less (P < 0.01) in the SILC group on postoperative day 7. © 2013 Japan Society for Endoscopic Surgery, Asia Endosurgery Task Force and Wiley Publishing Asia Pty Ltd.


Radhakrishnan H.,Mahatma Gandhi Institute
Indian Journal of Critical Care Medicine | Year: 2014

In most patients, wasp stings cause local reactions and rarely anaphylaxis. Acute kidney injury and rhabdomyolysis are unusual complications of wasp stings. We report a case of acute kidney injury and rhabdomyolysis secondary to multiple wasp stings. A 55-year-old farmer developed multi organ dysfunction with acute kidney injury and rhabdomyolysis 3 days after he had sustained multiple wasp stings. The etiology of acute kidney injury is probably both rhabdomyolysis and acute tubular necrosis. He improved completely after hemodialysis and intensive care. © 2014 Indian Journal of Critical Care Medicine. All right Reserved.


Patel D.J.,Mahatma Gandhi Institute
Journal of Indian Academy of Forensic Medicine | Year: 2012

FREEDOM FROM VIOLENCE, not necessarily proportional with development in some basic capabilities like nutrition, longevity and literacy which positively related to economic growth. So, dealing with violence in society is intrinsically a matter of public interest. In present study 79 cases of homicidal deaths due to different mechanical injuries was studied in two year period from 1/1/2009 to 31/12/2010. The incidence of homicidal death was 9.13% during this period. Males affected more in comparison to females. Majority of cases were fall in 21-40 yrs. of age comprising 50 cases (63.28%).Injuries by blunt weapons commonly observed in 30 cases (37.97%) which followed by injuries by sharp weapons 19 cases (24.05%). Totally 329 sharp injuries observed in comparison to 152 blunt injuries. Incidences were prevalent at dense forest area 26 cases (32.91%), in married persons 55 cases (69.62%), in between 6 pm to 12 midnight 24 cases (30.37%) and revenge was main motive 23 cases (29.11%).


Joshi D.,Mahatma Gandhi Institute | Buehring G.C.,University of California at Berkeley
Breast Cancer Research and Treatment | Year: 2012

The three viruses most studied as possible causes of human breast cancer are mouse mammary tumor virus-like sequences (MMTV-LS), Epstein-Barr virus (EBV), and oncogenic (high risk) types of human papilloma virus (HPV). The first step in fulfilling traditional criteria for inferring that a cancer is caused by a virus is to demonstrate the virus in the affected tissue. Molecular techniques, compared to host antibody assessment and immunohistochemistry, are the most definitive in establishing viral presence. Results of 85 original molecular research investigations to detect one or more of the three viruses have been extremely divergent with no consensus reached. We evaluated the methodology of these studies for the following: type of molecular assay, DNA/RNA quality control, positive and negative assay controls, type of fixation, genome targets, methods for preventing and detecting molecular contamination, pathology of specimens processed, sample size, and proportion of specimens positive for the viral genome region targeted. Only seven of the studies convincingly demonstrated the presence of an oncogenic virus biomarker (EBV: 4/30 studies (13%); HPV 3/29 studies (10%), whereas 25 convincingly demonstrated absence of the virus studied (MMTV-LS: 4/25 (16%); EBV: 15/30 (50%); 6/29 (21%). The remainder of the studies suffered shortcomings, which, in our opinion, prevented a definitive conclusion. Only one of the studies compared frequency of the virus in breast tissue of breast cancer patients versus appropriate normal control subjects with no history of breast cancer. None of the studies were designed as epidemiologic studies to determine if the presence of the virus was significantly associated with breast cancer. Based on our evaluation, the data in the publications reviewed here remain preliminary, and do not justify a conclusion that MMTV-LS, HPV, or EBV are causally associated with breast cancer. However, they form a valuable basis for redirecting future studies. © 2012 Springer Science+Business Media, LLC.


Kate V.,Post Graduate Institute of Medical Education and Research | Kalayarasan R.,GB Pant Hospital | Ananthakrishnan N.,Mahatma Gandhi Institute
Drugs | Year: 2013

Background: Several alternative treatment regimens for Helicobacter pylori eradication have been proposed since the efficacy of standard triple therapy has declined over time, and sequential therapy is one of them. The purpose of this systematic review is to analyze and compare the efficacy, adverse effects and cost of sequential therapy with that of standard triple therapy for H. pylori infection. Methods: MEDLINE, EMBASE, Google Scholar and Cochrane databases were used to retrieve all relevant articles published in the English language over the last 5 years (January 2008-October 2012). Eligibility criteria were randomized controlled trials (RCTs) comparing sequential and standard triple therapies in patients with documented H. pylori infection. Eligibility and quality of the trials were assessed independently by two reviewers, and the data regarding eradication rate, adverse effects and the cost of therapy were extracted. Results: Of the 17 RCTs included in the analysis (Asia 13, Europe 3, Latin America, 1), 12 reported better eradication rates with the sequential therapy, four did not find a significant difference between the two treatment regimens, and one reported a better eradication rate with standard triple therapy. All except one RCT reported no significant difference in the incidence of adverse effects between standard triple therapy and sequential therapy. Sequential therapy was cheaper than standard triple therapy in all three RCTs where a cost analysis was performed. The limitations of the RCTs included in the systematic review were that the sequential therapy regimen and the duration of standard triple therapy were not uniform. Antibiotic susceptibility tests were performed in only three RCTs. Conclusions: While the majority of the RCTs have shown superior eradication rates with sequential therapy, the largest RCT from Latin America did not find a significant difference between the two treatment regimens. Sequential therapy has good efficacy; however, further trials other than those from Asia and Italy are required to assess its superiority over existing regimens before recommending sequential therapy as the first line of treatment for H. pylori infection. © 2013 Springer International Publishing Switzerland.


De S.,Mahatma Gandhi Institute
The Indian journal of chest diseases & allied sciences | Year: 2011

Lidocaine is commonly used for topical anaesthesia during fibreoptic bronchoscopy (FOB) and it can cause methaemoglobinemia. The present study was undertaken to evaluate the severity of post-bronchoscopy methaemoglobinemia while using lidocaine as a topical anaesthetic agent. We prospectively studied consecutive adult patients who underwent diagnostic FOB in our institution. Blood methaemoglobin levels were estimated by co-oximetry before bronchoscopy and one hour after first instillation of lidocaine. Occurrence of symptoms suggestive of mild methaemoglobinemia (i.e., fatigue, palpitation, dizziness, nausea and headache) were recorded in a severity scale before collection of post-bronchoscopy blood samples. A total of 48 adult patients were enrolled in this study. The mean amount of lidocaine used for bronchoscopy during this study was 7.4 +/- 1.4 mg/kg body weight. The mean pre- and post-bronchoscopy methaemoglobin levels were 0.44 mg/mL and 0.80 mg/mL, respectively. After bronchoscopy, severe and very severe symptoms were reported by 2.1% to 10.4% patients. However, severities of the symptoms were unrelated to post-bronchoscopy methaemoglobin level or the amount of lidocaine used during the FOB. Blood methaemoglobin levels following FOB remained within the physiological limits when British Thoracic Society recommended dose of lidocaine was used. However, few patients had symptoms similar to mild methaemoglobinemia after FOB.


Malaria causes 216 million cases and an estimated 655000 deaths in 2010 in the world. 80.5% of the 109 billion population of India lives in malaria risk areas. The purpose of this study was to determine the knowledge, attitude and practices of malaria transmission and its prevention among the school going adolescents. A cross sectional study was conducted among school going adolescents in the rural area of District Wardha, Maharashtra, Central India. 1096 adolescents from eight government secondary schools were randomly selected. A pre-designed, pre-tested questionnaire was used for data collection. Data thus generated was entered in Microsoft Excel and analyzed using Epi Info 6.04 software package. Chi square value was used for testing the statistical significance. The mean age of the school going adolescents was 13.45 ± 1.91, for boys 13.43 ± 1.99 and 13.48 ± 1.85 year old for girls. About 84.7% of the respondents heard about the malaria disease and. 8.6% were aware about the causative agent. Transmission of malaria by mosquito bite was known to 69.8% of the adolescents. This was found significantly associated with male gender (X2 = 4.21, p = 0.03). Some of the adolescents had misconception regarding the mode of transmission of malaria like houseflies (32.8%). Nearly half (51.1%) of the adolescents had knowledge of symptoms of malaria as fever. None of the adolescents were aware about the new strategy of insecticide treated bed nets. Majority of the adolescents (57.7%) knew commonest breeding habits of mosquitoes as dirty stagnant water. The main source of information about malaria to most of the adolescents was television and radio (51.7%). About 47.4% of the adolescents practiced the prevention of breeding places of the mosquitoes by cleaning the surrounding. Nearly one fifth (20.7%) of the adolescents were using mosquito net. During the study, 66 (6.02%) adolescents were suffering from fever out of that 12.1% adolescents had taken self medication. Despite widespread knowledge about the morbidity of malaria, understanding about its transmission, treatment and prevention was low. It is imperative to involve the health workers to provide active support and empower teachers with information about malaria causation and prevention strategies so that such knowledge could be passed on to learners.


Madhusudhan Reddy G.,Defence Metallurgical Research Laboratory | Venkata Ramana P.,Mahatma Gandhi Institute
Journal of Materials Processing Technology | Year: 2012

Continuous drive friction welding of dissimilar metals, maraging steel and low alloy steel was carried out. It was observed that the hardness, ductility and impact toughness of maraging steel are low due to the diffusion of elements such as carbon, manganese, silicon and phosphorus from low alloy steel to maraging steel. An attempt was made in this study to improve the properties by friction welding of maraging steel and low alloy steel with nickel as an interlayer. The hardness, tensile strength and impact toughness are observed to be improved, as nickel acted as diffusion barrier. The effect of post-weld heat treatments on microstructure and mechanical properties of dissimilar metal friction welds with and without interlayer was also studied. Maraging steel responded to solutionizing & aging and low alloy steel responded to quenching and tempering. The notch tensile strength and impact toughness in case of dissimilar metal weld with interlayer are observed to be more than that of the dissimilar metal weld without interlayer. © 2011 Elsevier B.V. All rights reserved.

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