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Sodhi S.,Chatrapati Shahu Maharaj Shikshan Sanstha Dental College and Hospital | Sodhi J.S.,Sodhis Orthodontic Dental Clinic | Khambete N.,Chatrapati Shahu Maharaj Shikshan Sanstha Dental College and Hospital | Kumar R.,Mahatma Gandhi Missions Dental College and Hospital | And 2 more authors.
Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology | Year: 2014

Objective The objective of this case-control study was to evaluate the plasma tumor necrosis factor α (TNF-α) levels in patients with oral submucous fibrosis and to determine the relation of plasma TNF-α levels with the severity of oral submucous fibrosis. Study Design Blood samples were collected from 25 patients who were diagnosed with oral submucous fibrosis and from 25 age- and sex-matched control participants. The plasma was isolated by centrifugation of blood samples. The levels of plasma TNF-α were estimated using enzyme-linked immunosorbent assay. Results A total of 19 out of 25 patients had detectable plasma TNF-α levels ranging from 0.1 to 106.4 pg/mL (mean, 23.46 pg/mL), whereas only 12 out of 25 control participants had detectable plasma TNF-α levels ranging from 0.1 to 33.3 pg/mL (mean, 6.93 pg/mL). The difference between the TNF-α levels of patients and controls was statistically significant (P =.015) according to the Mann-Whitney test. Conclusions Patients with oral submucous fibrosis had significantly increased TNF-α levels compared with controls. © 2014 Elsevier Inc. All rights reserved. Source


Gadda R.,Mahatma Gandhi Missions Dental College and Hospital
BMJ Case Reports | Year: 2013

Neurological disorders and conditions affecting the maxillofacial region result in disabilities that affect an individual's functioning. Sensory or motor disturbances of the nerves may be caused by trauma, infections, pressure effect or infi ltration by tumours or other health conditions. Two rare cases of nerve afflictions are described here with their typical clinical features. The first case had an involvement of maxillary, mandibular and ophthalmic divisions of the trigeminal nerve (sensory) due to herpes zoster infection in a very young patient and the second case had a unilateral isolated hypoglossal nerve palsy (motor) secondary to infiltration of the nerve by carcinoma of pyriform fossa. Copyright 2013 BMJ Publishing Group. All rights reserved. Source


Nayak U.A.,Mahatma Gandhi Missions Dental College and Hospital | Khandelwal V.,Modern Dental College and Research Center | Nayak P.A.,Mahatma Gandhi Missions Dental College and Hospital | Thakur J.S.,Mahatma Gandhi Dental College and Hospital
BMJ Case Reports | Year: 2013

The most common consequence of traumatic dental injury is uncomplicated crown fracture. The main techniques for reconstructing fractured teeth include the use of direct adhesive restorative materials. However, this type of treatment is time consuming and requires a skilled operator. An alternative to the direct restorative technique is the use of a reference guide. The advantage is that the restorative procedure can be carried out in two short clinical sessions with a drastic reduction in chair time. The size, shape and inclination of the teeth are determined in advance, which reduces the need for eventual adjustments. In addition, the use of a reference guide makes it possible for two or more teeth to be restored simultaneously; in contrast, with the conventional technique. This paper offers a step-by-step description, of a reference guide technique for restoration of permanent maxillary incisors fractured through trauma. Copyright 2013 BMJ Publishing Group. All rights reserved. Source


Yadav S.R.,Mahatma Gandhi Missions Dental College and Hospital | Kini V.V.,Mahatma Gandhi Missions Dental College and Hospital | Padhye A.,Mahatma Gandhi Missions Dental College and Hospital
Journal of Clinical and Diagnostic Research | Year: 2015

Background: Chlorine dioxide (CIO2) is an oxidizing agent with known bactericidal, viricidal and fungicidal properties. Its efficacy in reducing the halitosis has been established by previous literature. However, data evaluating its antiplaque property is scarce. Chlorhexidine (CHX) is considered as the gold standard and an effective adjunctive to mechanical plaque removal. However, it is associated with few reversible side effects. Therefore a study was conducted to assess the antiplaque property of CIO2 containing mouthrinse against CHX mouthrinse. Aims and Objectives: To evaluate the efficacy of stabilized chlorine dioxide containing mouthrinse and CHX containing mouthrinse in inhibition of tongue coat accumulation and dental plaque formation using a four day plaque regrowth model clinically and microbiologically in a healthy dental cohort. Materials and Methods: A Single Center, Randomized, Triple blinded, Microbiological clinical trial was conducted involving 25 healthy dental students volunteers (11 males, 14 females). Two commercially available mouthrinse: Mouthrinse A – Aqueous based CIO2 mouthrinse Freshchlor® and Mouthrinse B - Aqueous based 0.2% CHX mouthrinse Hexidine® were selected as the test products. Subjects were asked to rinse and gargle for 1 minute with the allocated mouthrinse under supervision after supragingival scaling, polishing and tongue coat removal. After four hours, smears were taken from the buccal mucosa and tooth surface. On the fifth day from baseline of four day non brushing plaque regrowth model the samples were again taken from buccal mucosa and tooth surface followed by recording of plaque scores by Rastogi Modification of Navy Plaque index, extent of tongue coat by Winkel’s tongue coating index and measuring tongue coat wet weight in grams. The samples collected were subjected to microbial analysis and the results were expressed as colony forming units (CFUs) per sample. Statistical Analysis: The Data was analysed using SPSS 16.00 and presented using descriptive statistics. Independent t-test was used for the comparison between mouthrinse A groups & mouthrinse B group. Results: The plaque scores and Winkels tongue coat scores, wet tongue coat weight recorded on the fifth day after the use of the two mouthrinse didn’t show a statistically significant difference. The CFU per sample from tooth and mucosa after four hours revealed low bacteria count with respect to mouthrinse B however the CFU obtained on the fifth day did not show a statistically significant difference between the two mouthrinse. Conclusion: The clinical antiplaque efficacy of CHX and ClO2 mouthwash is comparable and so is the efficacy in reducing the oral bacterial load. © 2015, Journal of Clinical and Diagnostic Research. All rights reserved. Source


Iyer J.,Mahatma Gandhi Missions Dental College and Hospital | Pathak J.,Mahatma Gandhi Missions Dental College and Hospital | Patel S.,Mahatma Gandhi Missions Dental College and Hospital | Swain N.,Mahatma Gandhi Missions Dental College and Hospital
Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology | Year: 2016

An asymptomatic, blue, dome-shaped lesion on the buccal mucosa can include a plethora of entities clinically as well as histopathologically. Its clinical presentation may mimic reactive, developmental, benign or malignant conditions. This emphasizes the need on histopathological assessment of every docile looking lesion to explore its exact biological behavior. © 2016 Elsevier Inc. All rights reserved. Source

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