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Amrāvati, India

Heteroacyclic and Heterocyclic containing drugs showed remarkable and noticeable drug absorption, transmission and drug effects; hence they created their own identity and importance in pharmaceutical, medicinal, agricultural and drug sciences. Thioamido, pyridino, thiobiureto and alkylamino heterocyclic compounds showed various significances and applications in industrial, pharmaceutical, medicinal and drug chemistry. Considering all these facts into consideration it was thought interesting to synthesize 1-pyridino,1-[4(1-substituted)-2, 4-dithiobiureto]phenyl-dimethylpropanamine by interacting 1-pyridino,1-(4-thiocarbamido)phenyldimethylpropanamine with various isothiocynates in ethanol-acetone medium. The 1-pyridino,1-(4-thiocarbamido)phenyl-dimethylpropanamine was synthesized by interacting 3-(4-chlorophenyl)-N,N-dimethyl-3-pyridin-2-yl-propan-1-amine with thiourea in isopropanol medium. The justification and identification of the structure of these newly synthesized compounds had been established on the basis of chemical characterization, elemental analysis, and through spectral data. © 2011 RASĀYAN. All rights reserved. Source


Heteroacyclic and Heterocyclic containing drugs showed remarkable and noticeable drug absorption, transmission and drug effects; hence they created their own identity and importance in pharmaceutical, medicinal, agricultural and drug sciences. Thioamido, pyridino, thiobiureto and alkylamino heterocyclic compounds showed various significances and applications in industrial, pharmaceutical, medicinal and drug chemistry. Considering all these facts into consideration it was thought interesting to synthesize( 2-butyl-4- substitutedthiamldothiocarbamido-1- {[2-(1H-tetrazol-5-yl) biphenyl- 4-yl] methyl}-1H- imidazol-5-yl) methanol(5) by interacting (2-butyl-4-thiocarbamido- 1-{[2-(1H-tetrazol-5-yl) biphenyl- 4-yl] methyl}-1H- imidazol-5-yl) methanol(3) with various isothiocynates(4) in ethanol-acetone medium. The( 2-butyl-4- thiocarbamido-1-{[2-(1H-tetrazol-5-yl) biphenyl- 4-yl] methyl}-1H- imidazol-5-yl) methanol(3) was synthesized by interacting( 2-butyl-4 chloro-1-{[2-(1H-tetrazol-5yl) biphenyl 4yl ] methyl}-1H -imidazol-5- yl) methanol (1) with thiourea (2) in ¡sopropanol medium. The justification and identification of the structure of these newly synthesized compounds had been established on the basis of chemical characterization, elemental analysis, and through spectral data. Source


Chaudhari U.E.,Mahatma Fule Arts
Rasayan Journal of Chemistry | Year: 2014

The present investigations reveals the physico-chemical parameters of Satnoor and Naghthana dam water in warud region, Dist. Amravati(MS), Eight samples were collected in the month of January 2013. Physical and Chemical Parameters such as pH, TDS, Alkalinity, Total Hardness, Chlorides, Magnesium, Fluoride, Nitrates, Dissolve Oxygen and COD were studied The results indicate that, there is a marked variation in Physico-Chemical parameters of this dam water. © 2014 RASĀYAN. All rights reserved. Source


Ganorkar R.P.,Mahatma Fule Arts | Jamode V.S.,Sant Gadge Baba Amravati University
Oriental Journal of Chemistry | Year: 2010

By condensation of hydrazine hydrate with Bis-chalcones in pyridine medium titled BisPyrazolines have been synthesized. Structure of these compounds have been characterised by spectral analysis, all compounds have been evaluated for their In vitro growth inhibitory activity against different microbes like Staphylococcus aureus, Escherichia coli, Proteus mirabilis and Salmonella typhi. The solutions were prepared in DMF solvents.The culture medium used was nutrient agar medium. Source


Patil U.S.,Bharatiya Mahavidyalaya | Deshmukh O.S.,Mahatma Fule Arts
International Journal of Pharma and Bio Sciences | Year: 2016

Preliminary screening of phytochemicals is a valuable step, in the detection of the bioactive principles present in medicinal plants and subsequently may lead to drug discovery and development. In the present study, chief phytoconstituents of the six selected medicinal plants of different families were identified in order to relate their presence with bioactivities of the plants. Screening of six selected medicinal plants were performed for the presence of tannins, flavonoids, terpenoids, saponins, steroids, phlobatannins, carbohydrates, glycosides, coumarins, alkaloids, proteins, emodins and anthraquinones using standard methods. All the selected medicinal plants were found to contain Steroids and Coumarins except Urginea indica (Roxb.) Kunth and Wrightia tinctoria R.Br.respectively. Moreover, tannins and terpenoids were present only in Spatholobus purpureus Hassk. On the other hand, saponins were present in Terminalia bellirica L., Parthenocissus quinquefolia L. and Spatholobus purpureus Hassk. Carbohydrate were present in Wrightia tinctoria R.Br. and Spatholobus purpureus Hassk. plants. While alkaloids are present in Cyclea peltata Arn. ex Wight and Wrightia tinctoria R.Br. Whereas phlobatannins, emodins and glycosides were absent in all the selected six plants. It is evident from the study that Spatholobus purpureus Hassk. and Wrightia tinctoria R.Br. is of highest therapeutic efficacy possessing majority of phytochemical classes of compounds and Urginea indica (Roxb.) Kunth is of lowest therapeutic potential due to the absence of majority of phytoconstituents. Source

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