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Chandra Philip X.,Mahathma Gandhi Medical College and Research Institute | Prabavathy G.,Mahathma Gandhi Medical College and Research Institute
Research Journal of Pharmaceutical, Biological and Chemical Sciences | Year: 2014

Talus is the important tarsal bone which participates in the formation of talocrural, subtarsal and talocalcaneo-navicular joints. Anatomical variations of calcaneal articular facets on tali can be of help to Orthopaedic surgeons in pathologies of foot for reconstruction and rehabilitation procedures in many diseases of the foot such as Talocalcaneal arthritis, tarsal coalition, fracture neck of talus, congenital dysmorphology like flat foot, valgus deformity etc. So this study was aimed to observe the anatomical variations in tali. 200 adult human tali were studied from department of Anatomy, Mahathma Gandhi Medical College and Research Institute, Puducherry and other medical colleges in and around Puducherry. Each talus was examined for the presence of various patterns of articular facets. Later they were classified into five groups. Type I tali was found in 42 %. Type II in 30%, type III in 4% and type IV in 3% of cases. Type V had three subtypes, subtype A was present in 10%, B was in 9% and C was in 2%. In the present study, type I had highest incidence and type IV had lowest incidence.


Karthikeyan P.,Mahathma Gandhi Medical College and Research Institute | Paulraj P.,Mahathma Gandhi Medical College and Research Institute
Indian Journal of Otolaryngology and Head and Neck Surgery | Year: 2010

A 12-year-old girl presented to us with a swelling over the lateral surface of the right pinna of 4 years duration. Examination revealed an irregular mass arising from lateral surface of the pinna obscuring the external auditory canal. The lesion was not ulcerated. Wide excision of mass done and sent for Histopathological examination which revealed Tricho folliculoma. This case is being reported as it is a rare skin adnexal tumor arising from an unusual site. © 2010 Association of Otolaryngologists of India.


Shivakumar T.,Mahathma Gandhi Medical College and Research Institute | Sambandan A.P.,Mahathma Gandhi Medical College and Research Institute
Indian Journal of Otolaryngology and Head and Neck Surgery | Year: 2011

Chronic rhinosinusitis (CRS) is a common disease that restricts the quality of life of millions of involved patients. The aim of the study was to evaluate how functional endoscopic sinus surgery (FESS) modifies patients symptom profile and to also confirm that FESS is the modality of treatment in patients with refractory CRS. The study was retrospective analysis. 105 patients with symptoms of CRS were included in the study (between August 2006 to July 2009). Patients were assessed for CRS symptoms preoperatively and postoperatively using grading symptoms. Statistical analysis using Chi square test. Leading symptom of CRS was nasal obstruction followed by headache. Furthermore patients reported of anosmia, facial pressure, postnasal drip, purulent nasal discharge, halitosis, dental pain, cough, earache. None of the patients had fever as their complaint. After a postoperative followup of 6 months there was improvement in the symptoms. All minor symptoms had 100% improvement. Nasal obstruction responded best, next followed by (all symptoms P value <0. 001). An overall improvement of 86. 66% was recorded. The restriction of quality of life in patients with CRS is mainly caused by these symptoms, which can be improved in excellent fashion by FESS in majority of the patients. © 2011 Association of Otolaryngologists of India.


Ramasamy R.,Mahathma Gandhi Medical College and Research Institute | Gopal N.,Mahathma Gandhi Medical College and Research Institute | Srinivasan A.R.,Mahathma Gandhi Medical College and Research Institute | Murugaiyan S.B.,Mahathma Gandhi Medical College and Research Institute
Journal of Clinical and Diagnostic Research | Year: 2013

Purpose: The medical education is recently being transformed into several domains in order to adapt to the need and the value based academics which is required for the quality doctors who serve the community. Presently, the biochemistry curricula for the graduate students of medicine have been questioned by as many experts, because of their multiple lacunae. In this review, we would like to highlight the scenario which is related to the existing biochemistry curricula for graduate medical students, which have been followed in several medical schools and universities and we also hope to share our ideas for implementing objective and pragmatic curricula. Evidence based research, wherein the articles which are related to innovative teaching-learning tools are collected and the pros and cons which are related to the different methods analyzed in biochemistry point of view. Conclusion: Rapid changes in the content of the curriculum may not be required, but a gradual introduction of the novel approach and the methods of teaching biochemistry can be adopted into the curriculum.


Ramasamy R.,Mahathma Gandhi Medical College and Research Institute | Murugaiyan S.B.,Mahathma Gandhi Medical College and Research Institute | Gopal N.,Mahathma Gandhi Medical College and Research Institute | Shalini R.,Mahathma Gandhi Medical College and Research Institute
Journal of Clinical and Diagnostic Research | Year: 2013

Background: Ischemic heart disease accounts 12.2% deaths worldwide. Serum magnesium (Mg+) status is often ignored in Acute Myocardial Infarction (AMI). Studies showed alterations in the levels of serum electrolytes including magnesium in AMI. Aim: To evaluate serum Mg+ and other electrolytes as adjuvant markers in the diagnosis of AMI. Design and Settings: Case control study was conducted in South Indian male population with AMI within six hours of onset of symptoms. Patients and Methods: Study includes sixty patients with AMI and 100 controls. Serum electrolytes were estimated using electrolyte analyzer. Data were compared by using student't' test. ROC was drawn to find out optimum cutoff for diagnosing AMI. Pearson's correlation was done to see the association among the markers. Results: Serum Ca, Mg, K and Na electrolytes were significantly lower ('p'<0.001) in AMI. Ca:Mg, K:Mg, and Na:K ratios were significantly higher when compared to controls ('p'<0.001). There was significant correlation of serum Mg levels with other cardiac markers (Total CK, CK-Mb, Troponin -T) of AMI ('p' <0.05).ROC analysis of Na:Mg (40.9), Ca:Mg (3.43) and K:Mg (2.74) ratios showed optimum cutoffs in diagnosis of AMI. Conclusion: Serum Mg, Ca:mg, K:mg and Na:K ratios could be useful adjuvant markers in diagnosis of AMI.


PubMed | Mahathma Gandhi Medical College and Research Institute
Type: Journal Article | Journal: Indian journal of otolaryngology and head and neck surgery : official publication of the Association of Otolaryngologists of India | Year: 2012

A 12-year-old girl presented to us with a swelling over the lateral surface of the right pinna of 4 years duration. Examination revealed an irregular mass arising from lateral surface of the pinna obscuring the external auditory canal. The lesion was not ulcerated. Wide excision of mass done and sent for Histopathological examination which revealed Tricho folliculoma. This case is being reported as it is a rare skin adnexal tumor arising from an unusual site.


PubMed | Mahathma Gandhi medical college and research institute
Type: Journal Article | Journal: Journal of infection in developing countries | Year: 2011

There are few studies from India documenting the adverse effects of generic HAART (Highly Active Anti-retroviral Therapy).A prospective study was conducted at Mysore, India, to study the adverse effects after HAART initiation in a cohort of 100 antiretroviral therapy (ART)-naive patients, who were evaluated prospectively every three months by clinical and laboratory monitoring for adverse effects after HAART initiation for one year.The most common first-line regimens were zidovudine (AZT) plus lamivudine (3TC) plus nevirapine (NVP) (42%); followed by Stavudine (d4T) plus 3TC plus NVP (33%); AZT plus 3TC plus efavirenz (EFV) (13%); and d4T plus 3TC plus EFV (12%). The first-line regimen was modified in14% of patients. The most common reasons for modifying therapy were development of an adverse effect (eight cases; 57.14%) and completion of antituberculous therapy (six cases; 42.86%). The commonest cause for modifying therapy was skin rashes due to NVP (four cases) followed by anaemia two cases) and peripheral neuropathy (two cases). Grade 1 or 2 severity adverse effects by laboratory monitoring were seen in 54 patients after ART initiation and grade 3 or 4 severity adverse effects were seen in eight patients.A significant proportion of patients had adverse effects of a lower grade severity after HAART. A significant proportion of those started on ART substitute therapy due to adverse effects and those on NVP-based regimens are more likely to do so when compared with those on non-NVP- based regimens.


PubMed | Mahathma Gandhi Medical College and Research Institute
Type: Journal Article | Journal: Indian journal of otolaryngology and head and neck surgery : official publication of the Association of Otolaryngologists of India | Year: 2012

Chronic rhinosinusitis (CRS) is a common disease that restricts the quality of life of millions of involved patients. The aim of the study was to evaluate how functional endoscopic sinus surgery (FESS) modifies patients symptom profile and to also confirm that FESS is the modality of treatment in patients with refractory CRS. The study was retrospective analysis. 105 patients with symptoms of CRS were included in the study (between August 2006 to July 2009). Patients were assessed for CRS symptoms preoperatively and postoperatively using grading symptoms. Statistical analysis using Chi square test. Leading symptom of CRS was nasal obstruction followed by headache. Furthermore patients reported of anosmia, facial pressure, postnasal drip, purulent nasal discharge, halitosis, dental pain, cough, earache. None of the patients had fever as their complaint. After a postoperative followup of 6months there was improvement in the symptoms. All minor symptoms had 100% improvement. Nasal obstruction responded best, next followed by (all symptoms P value <0.001). An overall improvement of 86.66% was recorded. The restriction of quality of life in patients with CRS is mainly caused by these symptoms, which can be improved in excellent fashion by FESS in majority of the patients.

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