Maharajahs Institute of Medical science

Nellimarla, India

Maharajahs Institute of Medical science

Nellimarla, India

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Palo S.,Maharajahs Institute Of Medical Science | Biligi D.S.,Bangalore Medical College and Research Institute
Journal of Clinical and Diagnostic Research | Year: 2016

Multiple lymphomatous polyposis is considered to be a rare condition, with most of the cases being extranodal counterpart of mantle cell lymphomas. We report a rare case of multiple lymphomatous polyposis of the gastrointestinal tract in which the patient presented with abdominal pain and bloody diarrhea. Computer tomography of the abdomen showed circumferential wall thickening with intramural mass involving caecum & ascending colon with enlarged pericolonic lymph nodes. The patient underwent right hemicolectomy. Immunohistologic findings were characteristic of MALT lymphoma. Microscopic examination of polypoidal masses and mesenteric lymph nodes revealed infiltration by pleomorphic, atypical lymphoid cells which were CD20 positive and negative for CD3, CD10, Cyclin D1. Lymphoepithelial lesions were also noted. Careful endoscopic evaluation and histopathological review along with an immunohistochemical panel is extremely useful for accurately diagnosing such cases and avoiding unnecessary surgery and inappropriate therapy. © 2016, Journal of Clinical and Diagnostic Research. All rights reserved.


Palo S.,Maharajahs Institute Of Medical Science | Ahmed S.M.,Bangalore Medical College and Research Institute
Indian Journal of Public Health Research and Development | Year: 2016

Malignant proliferating trichilemmal cyst is a very rare adnexal tumor, usually arising on the head and neck region of elderly women. We describe a case of a 45-year-old lady presenting with right cervical region swelling since 6 months. Fine needle aspiration cytology and subsequent excisional biopsy was performed. Histopathology revealed lobules of atypical squamoid cells with high mitotic activity, trichilemmal keratinisation and focal invasion. A diagnosis of malignant proliferating trichilemmal cyst was made. It closely mimics squamous cell carcinoma and therefore, pose diagnostic dilemma for the pathologists. © 2016, Indian Journal of Public Health Research and Development. All rights reserved.


PubMed | Bangalore Medical College and Research Institute and Maharajahs Institute of Medical science
Type: Journal Article | Journal: Journal of clinical and diagnostic research : JCDR | Year: 2016

Multiple lymphomatous polyposis is considered to be a rare condition, with most of the cases being extranodal counterpart of mantle cell lymphomas. We report a rare case of multiple lymphomatous polyposis of the gastrointestinal tract in which the patient presented with abdominal pain and bloody diarrhea. Computer tomography of the abdomen showed circumferential wall thickening with intramural mass involving caecum & ascending colon with enlarged pericolonic lymph nodes. The patient underwent right hemicolectomy. Immunohistologic findings were characteristic of MALT lymphoma. Microscopic examination of polypoidal masses and mesenteric lymph nodes revealed infiltration by pleomorphic, atypical lymphoid cells which were CD20 positive and negative for CD3, CD10, Cyclin D1. Lymphoepithelial lesions were also noted. Careful endoscopic evaluation and histopathological review along with an immunohistochemical panel is extremely useful for accurately diagnosing such cases and avoiding unnecessary surgery and inappropriate therapy.


PubMed | MKCG Medical College & Hospital and Maharajahs Institute of Medical science
Type: Journal Article | Journal: Journal of obstetrics and gynaecology of India | Year: 2015

To compare the clinical results of three techniques of hysterectomy- abdominal hysterectomy (AH), non-descent vaginal hysterectomy (NDVH), and laparoscopic-assisted vaginal hysterectomy (LAVH).A simple prospective randomized study was performed in a tertiary care centre between June 2011 and Dec 2012, among 150 consecutive women indicated to undergo hysterectomy for benign and mobile uterine conditions. They were randomly assigned 50 each to three routes of hysterectomy; (abdominal, vaginal, and laparoscopic-assisted vaginal). Outcome measures including operating time, blood loss, rate of complications, consumption of analgesics, and length of hospital stay were assessed and compared between groups.As far as duration of operation, mean blood loss, analgesic requirement, length of hospital stay, P value was significant. Incidence of complications is least among VH group.Vaginal hysterectomy is the gold standard in the era of minimal access surgery. Some of the contraindications to VH can be overcome by assistance of laparoscope and a potential abdominal hysterectomy can be converted to a vaginal procedure.


Pramila Padmini M.,Maharajahs Institute of Medical science | Narasinga Rao B.,Maharajahs Institute of Medical science
Research Journal of Pharmaceutical, Biological and Chemical Sciences | Year: 2012

The Hindu formula concerns three types of prints: the Shankh which resembles the ulnar and radial loop; the Chakra or whorl; and the Shakti resembling the composite. The scientific study of papillary ridges of hands and feet is credited as beginning with the work of Joannes Evangelista Purkinje, a Chech psychologist and biologist in 1823. A dermtoglyphic survey on frequency of patterns and related personal attributes in medical students of MIMS medical college has been attempted. 212 students of MIMS admitted during 2004-2005 and 2005-2006 academic year were selected as the subjects for the study. One student has a tented arch, indicates student is enthusiastic. Ulnar loop incidence is 97%, which indicates conventional type of personality of students.


Sahoo A.K.,Maharajahs Institute Of Medical Science | Rauta S.,Maharajahs Institute Of Medical Science
Bangladesh Journal of Medical Science | Year: 2015

Background: Amoebic liver abscess presents with severe pain and high grade fever and if not diagnosed and treated promptly, may lead to complications and mortality.Aim and objectives: The objective of the present study was to estimate the incidence, need for aspiration and prognosis. The diagnosis was based on clinical features, positive Elisa test, ultrasonography, aspiration of anchovy sauce from the liver lesion, isolation of E. Histolytica (cyst/trophozoite) from the stool of the patient.Result: We had 65 cases in the study. There were 52 males & 13 females with a ratio of 4:1. Solitary abscess was found in 48 (73.8%) patients which are located as follows; right lobe(43), left lobe(2) and in both lobe(3). 9% were aspirated at presentation due to their size or position. Only 4 (2%) were aspirated at first follow-up on third day due to non resolution of pain or fever or increase in size. All the patients are responded to standard treatment of metronidazole. Amoebic liver abscess is a common diagnosis in our setup.Conclusion: Clinical background and sonogram give a reasonable suggestion about amoebic etiology. If initial aspiration is not indicated due to size larger than 10 cm or proximity to surface, conservative treatment with oral or intravenous metronidazole is successful. © 2015. Ibn Sina Trust. All Rights Reserved.


Kejriwal G.S.,Maharajahs Institute Of Medical Science | Madhavi C.,Maharajahs Institute Of Medical Science | Sahu S.N.,Maharajahs Institute Of Medical Science
Bangladesh Journal of Medical Science | Year: 2015

A female child of age five attended our institution in Jan 2006 with repeated upper respiratory infection. Plain skiagram and CT examinations confirmed the case to be a Scimitar syndrome. © 2015. Ibn Sina Trust. All Rights Reserved.


Rao R.R.,Maharajahs Institute of Medical science | Vijaya Kumar J.,Maharajahs Institute of Medical science | Prabha S.,Maharajahs Institute of Medical science
Research Journal of Pharmaceutical, Biological and Chemical Sciences | Year: 2015

To investigate the mode of action of phyllanthus niruri (P. niruri) as a prophylactic hepatoprotective agent against paracetamol (PCM) induced liver toxicity in albino rats. Five groups of six animals in each group of wistar rats with a weight of 180- 210 gms were the experimental material. Group I - Served as normal control, administered sodium CMC for all the eight days. Group II rats were treated only with PCM at a dose of 2.5 gm/kg on 8th day. Group III animals were administered silymarin at a dose of 50 mg/kg for 8days and PCM at a dose of 2.5 gm/kg on 8th day, while group IV is the treated group which was given P. niruri aqueous extract at a dose of 200mg/kg followed by PCM of 2.5 gm/kg on 8th day. Group V rats were administered with P. niruri at a dose of 400mg/kg for 8days and PCM at a dose of 2.5 gm/kg on 8th day. Biochemical, hisological and immunohistological (IHC) examinations were performed. Histopathological picture is in line with the biochemical parameters and IHC study revealed that P. NIRURI acts by preventing the increase in NKT cells subsequently blocking FASL, by antiapoptotic and by increasing regeneration. Phyllanthus niruri aqueous extract at a dose of 400 mg/kg was more effective than at 200mg and silymarin 100mg.


Sahoo A.K.,Maharajahs Institute Of Medical Science | Rauta S.,Maharajahs Institute Of Medical Science
Journal of Medicine (Bangladesh) | Year: 2014

A 39-year-old man of diabetic nephropathy presented with pruritic papulo-nodular brown lesions in both arms and legs on extensor surface characterized by central keratin plugs. Lesions were non-tender and numerous, crusted lesions which histologically were perforating disorders, showing features of Kyrle disease. The blood sugar of the patient was kept under control & hemodialysis was started. Dermatological lesions were treated by Isotretinoin, vitamin A, Tretinoin cream and oralantihistamines. © 2014, Bangladesh Society of Medicine. All rights reserved.


PubMed | Maharajahs Institute of Medical science
Type: Journal Article | Journal: Indian dermatology online journal | Year: 2016

Pachyonychia congenita is a rare type of ectodermal dysplasia further classified into 4 types. Cutaneous manifestations seen in most of the cases of Pachyonychia congenita include palmoplantar keratoderma, follicular hyperkeratosis, wedge shaped nails, oral leukokeratosis and woolly hair. A 25-year-old male presented to us with thickened nails and scanty scalp hair. On examination, we noticed hyperkeratotic plaques over both the soles, palmoplantar hyperhidrosis and yellowish discoloration, wedging with subungual hyperkeratosis of all the nails. Follicular hyperkeratotic papules and steatocystoma multiplex were also observed over the scalp and face. The patient had history of natal teeth and on dental examination, lower central incisors were absent. All cutaneous changes in our case had manifested first in the 2(nd) decade except for natal teeth. All the above features suggested the diagnosis of pachyonychia congenita with late onset (PC tarda), which is an infrequently reported rare variant.

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