Madha Medical College and Research Institute

Kovvūr, India

Madha Medical College and Research Institute

Kovvūr, India

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Vidhyashree M.D.,Sree Balaji Medical College and Hospital | Raveendran S.R.,Madha Medical College and Research Institute | Lakshmi Priya R.,ESIC Medical College and PGIMSR | Abiselvi A.,Sree Balaji Medical College and Hospital | Shalini S.,Sree Balaji Medical College and Hospital
Research Journal of Pharmaceutical, Biological and Chemical Sciences | Year: 2015

Children are more likely to have foods that are easily available and they tend to eat greater quantities when larger portions are provided. Additionally, characteristics of the social environment, including various socioeconomic and socio -cultural factors such as parents' education, time constraints, and ethnicity influence the types of foods children eat. children's consumption of fruits and vegetables (from seven day food records) was related to home availability and accessibility (as assessed by a parent telephone interview), after controlling for psychosocial characteristics. Mealtime structure includes social and physical characteristics of mealtimes including whether families eat together, TV-viewing during meals, and the source of foods (e.g., restaurants, schools)., children ate more fruits and vegetables for lunch at schools that offered more fruits and vegetables for lunch, after controlling for socioeconomic status. Parents also play a direct role in children's eating patterns through their behaviors, attitudes, and feeding styles. Interventions aimed at improving children's nutrition need to address the variety of social and physical factors that influence children's eating pattern.


Vidhyashree M.D.,Sree Balaji Medical College and Hospital | Raveendran S.R.,Madha Medical College and Research institute | Lakshmipriya R.,ESIC Medical College and PGIMSR | Kanmani Sree S.M.,Madha Medical College and Research institute | Radhika B.,Madha Medical College and Research institute
Research Journal of Pharmaceutical, Biological and Chemical Sciences | Year: 2014

Pleural effusion is a respiratory disorder characterized by collection of excess fluid between the parietal and visceral pleura of lung. Pleural fluid is meant for lubrication between the parietal and visceral pleura for the easy movement of lungs in thoracic cavity. The movement of lungs are restricted during ventilation because of abnormal collection of fluid. Pleural effusion can be due to, increased formation of pleural fluid or decreased re-absorption of pleural fluid from pleural space which can be due to congestive heart failure, hepatic cirrhosis, nephrotic syndrome, pulmonary embolism, malignancy, infection, pulmonary infarction. Diagnosis can be done by physical examination, chest radiography and analysis of pleural fluid. Managing pleural effusion is by diuretic therapy, thoracentesis, tube thoracostomy, pleurodesis, tunnelled pleural catheters (TPCs).


Kurhekar P.M.,Madha Medical College and Research Institute | Yachendra V.,Madha Medical College and Research Institute | Babu S.P.,Madha Medical College and Research Institute | Govindasamy R.,Madha Medical College and Research Institute
Indian Journal of Anaesthesia | Year: 2014

Cardiac arrest associated with spinal anaesthesia has been well researched. Myocardial stunning after successful resuscitation from cardiac arrest is seen in up to 2/3rd of in-hospital cardiac arrests. Myocardial stunning after resuscitation from cardiac arrest associated with spinal anaesthesia has probably not been reported earlier. Our case, an ASA physical status I lady, posted for tubal reanastomosis surgery developed bradycardia followed by asystole, approximately 5 minutes after giving subarachnoid block. Return of spontaneous circulation (ROSC) was achieved within 2 minutes with cardiopulmonary resuscitation (CPR) and defibrillation for pulseless ventricular tachycardia. Patient developed delayed pulmonary oedema, which was probably due to myocardial stunning. In the present case, inadequate preloading could have precipitated bradycardia progressing to cardiac arrest which, after resuscitation led to reversible myocardial dysfunction. We conclude that early vasopressor infusion, titrated fluids and echocardiography should be considered in immediate post cardiac arrest phase following spinal anaesthesia.


Kurhekar P.,Madha Medical College and Research Institute | Kumar S.M.,Madha Medical College and Research Institute | Sampath D.,Madha Medical College and Research Institute
Indian Journal of Anaesthesia | Year: 2016

Background and Aims: Inrathecal opioids like morphine added to local anaesthetic agents have been found to be effective in achieving prolonged post-operative analgesia. Intrathecal dexmedetomidine may be devoid of undesirable side effects related to morphine and hence, this study was designed to evaluate analgesic efficacy, haemodynamic stability and adverse effects of both these adjuvants in patients undergoing gynaecological surgeries. Methods: This was a prospective, randomised, double blind study involving 25 patients in each group. Group M received 15 mg of 0.5% hyperbaric bupivacaine with 250 µg of morphine while Group D received 15 mg of 0.5% hyperbaric bupivacaine with 2.5 µg of dexmedetomidine. Characteristics of spinal block, time for first rescue analgesic and total dose of rescue analgesics were noted. Vital parameters and adverse effects were noted perioperatively. Data analysis was done with independent two sample t-test and Mann–Whitney U test. Results: Time for first rescue analgesic (P = 0.056) and total analgesic demand were similar in both groups. Duration of sensory (P = 0.001) and motor (P = 000) block was significantly higher in dexmedetomidine group. Itching was noticed in 36% and nausea in 52% of patients in the morphine group, either of which was not seen in dexmedetomidine group. Conclusion: Intrathecal dexmedetomidine produces prolonged motor and sensory blockade without undesirable side effects but intraoperative hypotension was more frequent in dexmedetomidine group. © 2016 Indian Journal of Anaesthesia.


Ramar S.,Madha Medical College and Research Institute | Saraswathi P.,Saveetha University
Journal of Clinical and Diagnostic Research | Year: 2013

Aim: The histomophometric study of Fructus Psoralea (FP) on ethanol induced neurodegeneration of hippocampus was investigated in a rat by using micrometry. Material and Methods: The study was conducted on thirty healthy female adult wistar albino rats with regular 4-day estrus cycles. The experiment was carried out for a period of 2-4 months. The rats were divided into- SHAM operated control group (Group I) and experimental groups - overiectomised vehicle control rat ((Group II), OVX and orally treated with FP(Group III) OVX and induced with ethanol (Group IV), OVX rats induced with ethnaol and orally treated with FP (Group V). ANOVA tool was used to test the mean positive behavioural activity of all the groups. The diameter, packing density and the total number of neurons were calculated from toluidine blue stained histological section by using micrometry. The statistical package SPSS (17.0 VERSION) was used. Statistical significance was defined as p < 0.05. Data was expressed as mean ± SEM. Discussion: In animal studies, ethanol was found to significantly inhibit neuronal activity in the CA1 and CA3 pyramidal cell layers of the hippocampus. FP increase the number of cholinergic neurons in the basal forebrain which in turn leads to increased function of hippocampus, a structure heavily implicated in behavioural activity and memory consolidation. Conclusion: People with extensive hippocampal damage may experience amnesia, learning and memory disabilities. Hence the herb FP may be used as an adjuvant to treat the above neurological disorders.


PubMed | Madha Medical College and Research Institute
Type: Journal Article | Journal: Indian journal of anaesthesia | Year: 2014

Cardiac arrest associated with spinal anaesthesia has been well researched. Myocardial stunning after successful resuscitation from cardiac arrest is seen in up to 2/3(rd) of in-hospital cardiac arrests. Myocardial stunning after resuscitation from cardiac arrest associated with spinal anaesthesia has probably not been reported earlier. Our case, an ASA physical status I lady, posted for tubal reanastomosis surgery developed bradycardia followed by asystole, approximately 5 minutes after giving subarachnoid block. Return of spontaneous circulation (ROSC) was achieved within 2 minutes with cardiopulmonary resuscitation (CPR) and defibrillation for pulseless ventricular tachycardia. Patient developed delayed pulmonary oedema, which was probably due to myocardial stunning. In the present case, inadequate preloading could have precipitated bradycardia progressing to cardiac arrest which, after resuscitation led to reversible myocardial dysfunction. We conclude that early vasopressor infusion, titrated fluids and echocardiography should be considered in immediate post cardiac arrest phase following spinal anaesthesia.


PubMed | Madha Medical College and Research Institute
Type: Journal Article | Journal: Indian journal of anaesthesia | Year: 2016

Inrathecal opioids like morphine added to local anaesthetic agents have been found to be effective in achieving prolonged post-operative analgesia. Intrathecal dexmedetomidine may be devoid of undesirable side effects related to morphine and hence, this study was designed to evaluate analgesic efficacy, haemodynamic stability and adverse effects of both these adjuvants in patients undergoing gynaecological surgeries.This was a prospective, randomised, double blind study involving 25 patients in each group. Group M received 15 mg of 0.5% hyperbaric bupivacaine with 250 g of morphine while Group D received 15 mg of 0.5% hyperbaric bupivacaine with 2.5 g of dexmedetomidine. Characteristics of spinal block, time for first rescue analgesic and total dose of rescue analgesics were noted. Vital parameters and adverse effects were noted perioperatively. Data analysis was done with independent two sample t-test and Mann-Whitney U test.Time for first rescue analgesic (P = 0.056) and total analgesic demand were similar in both groups. Duration of sensory (P = 0.001) and motor (P = 000) block was significantly higher in dexmedetomidine group. Itching was noticed in 36% and nausea in 52% of patients in the morphine group, either of which was not seen in dexmedetomidine group.Intrathecal dexmedetomidine produces prolonged motor and sensory blockade without undesirable side effects but intraoperative hypotension was more frequent in dexmedetomidine group.


PubMed | Madha Medical College and Research Institute
Type: Journal Article | Journal: Journal of clinical and diagnostic research : JCDR | Year: 2013

The histomophometric study of Fructus Psoralea (FP) on ethanol induced neurodegeneration of hippocampus was investigated in a rat by using micrometry.The study was conducted on thirty healthy female adult wistar albino rats with regular 4-day estrus cycles. The experiment was carried out for a period of 2-4 months. The rats were divided into- SHAM operated control group (Group I) and experimental groups - overiectomised vehicle control rat ((Group II), OVX and orally treated with FP(Group III) OVX and induced with ethanol (Group IV), OVX rats induced with ethnaol and orally treated with FP (Group V). ANOVA tool was used to test the mean positive behavioural activity of all the groups. The diameter, packing density and the total number of neurons were calculated from toluidine blue stained histological section by using micrometry. The statistical package SPSS (17.0 VERSION) was used. Statistical significance was defined as p < 0.05. Data was expressed as mean SEM.In animal studies, ethanol was found to significantly inhibit neuronal activity in the CA1 and CA3 pyramidal cell layers of the hippocampus. FP increase the number of cholinergic neurons in the basal forebrain which in turn leads to increased function of hippocampus, a structure heavily implicated in behavioural activity and memory consolidation.People with extensive hippocampal damage may experience amnesia, learning and memory disabilities. Hence the herb FP may be used as an adjuvant to treat the above neurological disorders.

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