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PubMed | Sathyabama University, Madha Dental College & Hospital, Sibar Institute of Dental science and Malabar Dental College and Research Center
Type: Journal Article | Journal: Journal of international oral health : JIOH | Year: 2015

Myofibroblasts after its discovery in 1971 as the principal cell for wound healing has come a long way as far as research is concerned. The primary focus of research has been regarding preventing certain unwanted effects of this cell such as wound contraction and scarring. As far as the oral and maxillofacial region is concerned, the primary concern of this untoward effect is during repair of cleft palate surgically which results impaired development of palate and the dentoalveolar structures. This review focuses on the basic aspects of myofibroblasts such as its origin, formation, function in wound healing, role in wound contraction and ways by which its unwanted effects can be overcome to improve the quality of the post surgical complications of cleft palate surgery.


PubMed | Madha Dental College & Hospital, General Dental Practitioner, Madha Dental College and Hospital, University of Technology Malaysia and Rajah Muthiah Dental College and Hospital
Type: Journal Article | Journal: Journal of international oral health : JIOH | Year: 2015

Pseudoepitheliomatous hyperplasia (PEH), a neglected entity by oral pathologist possesses utmost importance in the field of research. Of all the investigative challenges, PEH, a reactive epithelial proliferation is seen secondary to lesions with infectious, inflammatory, reactive, and degenerative origin. Small sized samples, incomplete excision, improper orientation, and dense inflammatory changes render diagnostic confront to the oral pathologist in exclusion of frankly invasive malignant lesions like squamous cell carcinoma from lesions exhibiting PEH. The diagnosis can occasionally be difficult as they mimic other lesions also, on clinic-pathological assessment. Thus, this article gives an insight regarding the various concepts of etiopathogenesis, histopathology, differential diagnosis, and malignant potential of PEH. A combined effort of a clinician and pathologist benefits every patient to rule out malignancy and render appropriate treatment as the only local conservative approach is essential to remove PEH associated lesions.


PubMed | Madha Dental College & Hospital, Saveetha Dental College & Hospital and Chettinad Dental College & Research Institute
Type: Journal Article | Journal: Journal of international oral health : JIOH | Year: 2015

This randomized, double-blind, parallel arm study was carried out to evaluate and compare the effectiveness between nano-hydroxyapatite (HAP) and a benchmark dentifrice in reducing dentin hypersensitivity.About 36 patients were selected, randomly divided into two groups and was evaluated clinically using three different stimuli, i.e., tactile, air blast, and cold water test. The patients responses to various stimuli were recorded using a visual analog scale at baseline and after 4 weeks.Statistical analysis was done using unpaired and paired t-tests. It was seen that patients treated in both groups showed significant reductions scores across all sensitivity measures at the end of 4 weeks.The HAP containing toothpaste was effective in reducing dentin hypersensitivity with pre-existing benchmark toothpaste tested and hence can be advocated in the management of hypersensitivity.


PubMed | Madha Dental College & Hospital
Type: Journal Article | Journal: Journal of international oral health : JIOH | Year: 2015

Gorlin-Goltz syndrome is an autosomal dominant inherited condition comprising the principle triad of basal cell carcinomas, multiple jaw keratocysts, and skeletal anomalies. The presence of jaw cysts are the early diagnostic feature of this syndrome, and this can be incidentally identified by routine radiographs. A patient presented with signs and symptoms of Gorlin-Goltz syndrome to us in her early stages.


PubMed | Madha Dental College & Hospital, Thai Mookambigai Dental College, Rajah Muthaiah Dental College & Hospital, Madha Dental College and Tagore Dental Colleg & Hospital
Type: Journal Article | Journal: Journal of clinical and diagnostic research : JCDR | Year: 2015

The antibacterial properties of wine and ozone have been established but their antibacterial efficacies against endodontic pathogens are yet to be ascertained.The purpose of this study is to comparatively evaluate the antibacterial property of ozonated water, white wine (14%) and de-alcoholised white wine.S.mutans and E.faecalis were subcultured and inoculated in a nutrient broth for 24 hours. The following groups were formulated: Group 1A:2% Chlorhexidine (Control group); Group 1B:White wine; Group 1C:Dealcoholised white wine; Group 1D:Ozonated water; Group 2A: Ca(OH)2 + Chlorhexidine (Control group); Group 2B: White wine + Ca(OH)2; Group 2C:De-alcoholised White wine + Ca(OH)2 + chlorhexidine; Group 2D:White wine + Ca(OH)2 + chlorhexidine and group 2E: Dealcoholised white wine + Ca(OH)2 + chlorhexidine. The samples were allowed to diffuse into the culture medium for two hours, later the S. mutans were streaked on to the blood agar medium and the E. faecalis were streaked on to the Muller Hilton agar medium and incubated for 48 hours at 370C the zone of inhibition was measured after 48 hours.There was no growth of microorganisms seen with ozonated water. Chlorhexidine showed large zone of inhibition compared to the other groups. White wine has better antimicrobial property than de-alcoholised white wine, but when mixed with calcium hydroxide the dealcoholised white wine has better action against the microorganisms.Ozonated water has the best antibacterial property and the antibacterial action of Calcium hydroxide is enhanced when it is mixed with de-alcoholised white wine.


PubMed | Madha Dental College & Hospital, Raja Rajeshwari Dental College, KKR, Karpaga Vinayaga Institute of Dental science and Sree Mookambika Institute of Dental science
Type: Journal Article | Journal: Journal of international oral health : JIOH | Year: 2015

Comparison of the demineralization potential of four luting cements, i.e. zinc phosphate, conventional glass ionomer cement (GIC), resin-modified GIC and acid modified composite resin.This study was conducted on 75 extracted premolar teeth, which were grouped into five, each group containing 15 teeth. Groups were non-banded control, teeth cemented with the above-mentioned cements. These were incubated at 37C for 30 days in sealable plastic containers, after which the teeth were debanded, cleaned and placed in acid gelatin solution at 37C for 4 weeks to simulate the cariogenic solution. Then, the teeth were sectioned and examined under scanning electron microscope. The depth of the carious lesions was measured using image analysis with Digimizer software.The depth of the carious lesions was maximum with non-banded group, followed by zinc phosphate, acid modified composite resin, resin-modified GIC and conventional GIC.Among the four orthodontic banding cements compared, the enamel demineralization potential is least with conventional GIC, followed by resin-modified GIC, acid modified composite resin and zinc phosphate.

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