Macquarie University is a public research university based in Sydney, Australia, in the suburb of Macquarie Park. Founded in 1964 by the New South Wales Government, it was the third university to be established in the metropolitan area of Sydney. It is the fourth largest university in Sydney.The university comprises five faculties. Also affiliated with the university are several research centres, schools and institutes including the Macquarie Graduate School of Management, Australian Proteome Analysis Facility, the Institute of Human Cognition and Brain Science, the Macquarie University Research Park and the Macquarie University Hospital. At present, the university offers 87 undergraduate courses and 124 different postgraduate courses to students. The university is governed by a 17-member Council.Macquarie is ranked in the top 40 universities in the Asia-Pacific region and within Australia's top ten universities according to the Academic Ranking of World Universities, the U.S. News & World Report Rankings and the QS World University Rankings. According to the QS World University Rankings, Macquarie is the highest ranked university in Australia under the age of 50, it is ranked 18th in the world. Macquarie is ranked in the 201st-300th bracket and 8th-9th in Australia in the 2013 Academic Ranking of World Universities. The university is also ranked among the national top five recipients of relative research income. Macquarie University also has the largest student exchange programme in Australia.Researchers at Macquarie University, David James Skellern and Neil Weste, and the Commonwealth Scientific and Industrial Research Organisation helped develop Wi-Fi. David James Skellern has been a major donor to the University through the Skellern Family Trust. Macquarie University's linguistics department developed the Macquarie Dictionary. The dictionary is regarded as the standard reference on Australian English. Wikipedia.
News Article | May 15, 2017
A mongoose on a leash, a colorful pelican and various bats are just a few of the rare animal drawings revealed in a new survey of a group of 4,000-year-old tombs in Egypt. The tombs are located at the Beni Hassan cemetery and were excavated and detailed in a publication over a century ago by archaeologist Percy Newberry and his colleagues, wrote Linda Evans, a senior lecturer at Macquarie University in Australia, in an article published recently in the Journal of the American Research Center in Egypt. Now, Evans and other archaeologists at Macquarie University's Australian Centre for Egyptology are re-surveying the tombs using modern-day technology. Recently, an Egyptian antiquities ministry team also conserved and cleaned the tombs. [See Photos of the Ancient Egyptian Tombs and Colorful Drawings] The conservation and recording has "revealed many scenes not found in Newberry's reports," wrote Evans. In addition, the new work has identified creatures in the drawings that Newberry had been uncertain about. For instance, Newberry noted only the possible existence of a leashed Egyptian mongoose, a burrowing animal with a speckled gray coat, writing down the identification as a suggestion. Some Egyptologists who reviewed his reports thought the identification was incorrect, Evans noted. "No other images of leashed mongooses are known in Egyptian art," Evans wrote. Evans' team determined that the animal is "morphologically identical" to the Egyptian mongoose, wrote Evans, noting that the animal is also clearly depicted on a leash. "The animal clearly sports a gray collar that tapers to join a long, gray leash, which is held in the left hand of a bearer, who also holds the leash of a spotted hunting dog situated below the mongoose," Evans said. The tomb belonged to Baqet I, a nomarch or provincial governor, who ruled during the 11th Dynasty. The researchers said they don't know why an ancient Egyptian artist drew a leashed mongoose on Baqet I's tomb. "While mongooses have never been fully domesticated — that is, subjected to controlled breeding — some cultures have chosen to keep the animals as pets in order to control unwanted pests, such as snakes, rats and mice," Evans wrote. The leashed mongoose shown on the tomb may have been used to scare birds so that they would fly out of the bush, making it easier for Egyptian hunters (who are depicted near the mongoose) to hunt them, according to Evans. A wall on another tomb, this one belonging to another 11th Dynasty nomarch, Baqet II, is decorated with an image of a pelican, its colors still preserved despite the passage of 4,000 years. Newberry never saw or at least never recorded the pelican, Evans noted in the journal article. [In Photos: Ancient Egyptian Coffin with 'Odd' Art] Pelicans "are rarely encountered in Egyptian art," though three species of pelican are known to pass over or winter in Egypt, Newberry wrote. The image "shows awareness of subtle behavior details," Evans added, noting that the artist depicted the bird holding its feet at an "unusually abrupt angle," in what appears to be an attempt to show a movement that pelicans are known to make. "When lifting off from the water, pelicans first hop across the surface for a number of meters, while simultaneously flapping their wings, thrusting their feet forward and back in unison in order to gain both lift and momentum," Evans wrote. The pelican drawn on the tomb appears to be in "midhop as it becomes airborne," she added. The researchers are recording and analyzing additional creatures depicted at the site, Evans said. In one tomb, the team found batdrawings that Newberry was not aware of. "Representations of bats are extremely rare" in ancient Egyptian art, Evans told Live Science in an email. The team is analyzing the bat images, which will be described in a future journal article, Evans said. The researchers said they aren't sure why so many animals, especially birds, are shown in the tombs at Beni Hassan. One painting, for instance, shows no fewer than 29 birds and three bats Evans said. "The striking preponderance of birds at the site may indicate a special role for the animals in the lives of the local inhabitants, or perhaps the region once attracted an unusual variety of birds, possibly serving as a stopover for migratory species," Evans wrote in the journal article, adding in an email that the "climate was probably somewhat milder than modern-day Egypt — not as hot and dry."
News Article | May 24, 2017
LONDON--(BUSINESS WIRE)--FutureStack — Digital intelligence leader New Relic, Inc. (NYSE:NEWR) unveiled new capabilities to the New Relic Digital Intelligence Platform that will enable enterprises to have greater visibility into the performance of their applications and the dynamic infrastructure that they rely on. With the new Health Map, New Relic is bringing together the power of New Relic APM and New Relic Infrastructure to deliver a high-density view of applications and the infrastructure supporting those applications. By standardizing monitoring within a single cloud platform, customers will be able to work better together to pinpoint issues and optimize their dynamic cloud or hybrid environments, in particular those leveraging Amazon Web Services (AWS). A bird’s-eye view of large and complex environments. As enterprises adopt more scalable microservice architectures, it becomes more difficult to pinpoint performance issues within the application stack. New Relic’s new Health Map feature brings together insights on application and infrastructure performance into a single, prioritized view. This unified view enables operations and DevOps teams to quickly understand if the source of a performance issue is from the application code or in the infrastructure layer. Integrated to support your AWS strategy. New Relic Infrastructure now boasts 20 out-of-the-box integrations to AWS services, including new integrations for Amazon Kinesis Firehose, Amazon Elasticsearch Service, Amazon Route 53, Amazon EC2 Container Service, and Amazon EC2 Container Registry. In addition, Billing and Cost Management features have been introduced, which will enable customers to monitor costs in real time and plan for the future. The breadth of New Relic’s integrations enable enterprises to effectively migrate, optimize, and scale the usage and data flow within AWS. Extend New Relic Infrastructure to monitor any custom host. With New Relic Infrastructure's new SDK, system administrators and DevOps teams can now standardize the monitoring of custom services alongside dynamic infrastructure instances within the context of the applications that they support. This visibility can lead to these teams improving their efficiency in diagnosing and resolving problems by viewing all the relevant information from a single source. “Enterprises are rapidly moving to dynamic infrastructure and scalable architectures so that they can move at the speed of the business. Our customers want a single monitoring platform, and New Relic is delivering end-to-end visibility and metrics that operations teams need to understand the health of all their applications, down to any host in their environment,“ said Jim Gochee, chief product officer, New Relic. “Macquarie is in the middle of a transformational change, and determining how we deliver and monitor infrastructure services to support the university’s requirements, both now and in the future, will be key to our success. New Relic’s new Health Map provides us a single pane of glass view displaying both the status of our environment as well as the relationships between our applications and the infrastructure that supports them. With the flexibility to provide an applications perspective of the environment, applications and their related hosts or an infrastructure perspective, hosts and their related applications, the Health Map display caters for the needs of a diverse support team; assisting the Help desk, Infrastructure, Applications and Development teams providing the necessary information to manage and support a large number of diverse systems and applications,” said Gavin Wilson, infrastructure manager, Macquarie University, one of Australia’s leading public research universities. “Historically, Spokeo has used lots of monitoring tools and we started consolidating our monitoring with New Relic because it gives us a holistic view of our applications and infrastructure. New Relic Infrastructure alerts us to server specific errors and the Health Map gives us the ability to understand our metrics in one dashboard. The integrations with AWS products have been pretty interesting to see and given us an automated way to pull in metrics in real time to understand the performance of those services in relation to the applications they support,” said Eric Liang, co-founder and chief information officer, Spokeo, a people search engine founded in California. Health Map is expected to be available at the end of May 2017 for paying New Relic APM customers who have either purchased or are trialing New Relic Infrastructure. For a free 30-day trial of New Relic Infrastructure visit here. The AWS integrations and New Relic Infrastructure SDK are immediately available to all Professional customers. Read blog posts on the latest updates to the Digital Intelligence Platform, the new Health Map, and New Relic Infrastructure’s AWS integrations. New Relic will be hosting a webinar on Thursday, June 15, 2017, at 11:00 AM PDT, Spring '17 New Relic Digital Intelligence Platform Updates. To register for the webinar and learn more about what's new in the New Relic Digital Intelligence Platform, visit here. Please note that events, dates, topics, and speakers are subject to change without notice. New Relic is a leading digital intelligence company, delivering full-stack visibility and analytics to over 40% of the Fortune 100. The New Relic Digital Intelligence Platform provides actionable insights to drive digital business. Companies of all sizes trust New Relic to monitor application and infrastructure performance so they can quickly resolve issues, and improve digital customer experiences. Learn more at newrelic.com. This press release contains “forward-looking” statements, as that term is defined under the federal securities laws, including but not limited to statements regarding the New Relic Digital Intelligence Platform, particularly with respect to products and features thereof that are expected to be delivered in the future, such as health maps, as well as market trends and dynamics and future webinar events. The achievement or success of the matters covered by such forward-looking statements are based on New Relic’s current assumptions, expectations, and beliefs and are subject to substantial risks, uncertainties, assumptions, and changes in circumstances that may cause New Relic’s actual results, performance, or achievements to differ materially from those expressed or implied in any forward-looking statement. Further information on factors that could affect New Relic's financial and other results and the forward-looking statements in this press release is included in the filings New Relic makes with the SEC from time to time, including in New Relic's most recent Form 10-K, particularly under the captions "Risk Factors" and "Management's Discussion and Analysis of Financial Condition and Results of Operations." Copies of these documents may be obtained by visiting New Relic's Investor Relations website at http://ir.newrelic.com or the SEC's website at www.sec.gov. New Relic assumes no obligation and does not intend to update these forward-looking statements, except as required by law. New Relic is a registered trademark of New Relic, Inc. All product and company names herein may be trademarks of their registered owners.
News Article | May 25, 2017
Studying biological events while they happen is essential to truly understanding the full process behind each occurrence. Live cell imaging using fluorescence microscopy is the perfect approach to explore these complex questions. In this webinar, the use of automated fluorescence microscopy methods will be discussed, from small animal models and tissues to individual organelle and protein observations using high content analyzers. Attendees will see demonstrations on how to capture high quality data while utilizing best methods for ensuring sample viability, including environmental control, sensitive signal detection, and precise instrument control. Participants will learn of the advantages of using live samples for HCA, along with the importance of quantitative analysis. Ultimately gaining an understanding of imaging system requirements for live cell observation. The team at GE Healthcare has selected Dr. Lynne Turnbull, lead applications support specialist at GE Healthcare, to be the speaker at this event. Turnbull completed her doctoral studies at Macquarie University, in Sydney, Australia and is best known for her research in microbial biofilms and cell biology. She recently joined GE Healthcare as a lead application support specialist, where her research interests focus on microbial biofilms and the application of optical and super resolution imaging techniques to the study of microbial cell biology. LabRoots will host the webinar June 14, 2017, beginning at 8 a.m. PDT, 11 a.m. EDT. To read more about this event, learn about the continuing education credits offered, or to register for free, click here. ABOUT GE GE Healthcare provides transformational technologies and services to meet the demand for increased access, enhanced quality and more affordable healthcare around the world. GE (NYSE: GE) works on things that matter - great people and technologies taking on tough challenges. The Life Sciences business of GE Healthcare exists to enable scientific discovery. We do this by helping our customers discover, make and use new ways to improve the human condition. ABOUT LABROOTS LabRoots is the leading scientific social networking website, which provides daily scientific trending news and science-themed apparel, as well as produces educational virtual events and webinars, on the latest discoveries and advancements in science. Contributing to the advancement of science through content sharing capabilities, LabRoots is a powerful advocate in amplifying global networks and communities. Founded in 2008, LabRoots emphasizes digital innovation in scientific collaboration and learning, and is a primary source for current scientific news, webinars, virtual conferences, and more. LabRoots has grown into the world’s largest series of virtual events within the Life Sciences and Clinical Diagnostics community.
Gillings M.R.,Macquarie University
Microbiology and Molecular Biology Reviews | Year: 2014
Integrons are versatile gene acquisition systems commonly found in bacterial genomes. They are ancient elements that are a hot spot for genomic complexity, generating phenotypic diversity and shaping adaptive responses. In recent times, they have had a major role in the acquisition, expression, and dissemination of antibiotic resistance genes. Assessing the ongoing threats posed by integrons requires an understanding of their origins and evolutionary history. This review examines the functions and activities of integrons before the antibiotic era. It shows how antibiotic use selected particular integrons from among the environmental pool of these elements, such that integrons carrying resistance genes are now present in the majority of Gram-negative pathogens. Finally, it examines the potential consequences of widespread pollution with the novel integrons that have been assembled via the agency of human antibiotic use and speculates on the potential uses of integrons as platforms for biotechnology. Copyright © 2014, American Society for Microbiology. All Rights Reserved.
Gillings M.R.,Macquarie University
Frontiers in Microbiology | Year: 2013
The widespread use and abuse of antibiotic therapy has evolutionary and ecological consequences, some of which are only just beginning to be examined. One well known consequence is the fixation of mutations and lateral gene transfer (LGT) events that confer antibiotic resistance. Sequential selection events, driven by different classes of antibiotics, have resulted in the assembly of diverse resistance determinants and mobile DNAs into novel genetic elements of ever-growing complexity and flexibility. These novel plasmids, integrons, and genomic islands have now become fixed at high frequency in diverse cell lineages by human antibiotic use. Consequently they can be regarded as xenogenetic pollutants, analogous to xenobiotic compounds, but with the critical distinction that they replicate rather than degrade when released to pollute natural environments. Antibiotics themselves must also be regarded as pollutants, since human production overwhelms natural synthesis, and a major proportion of ingested antibiotic is excreted unchanged into waste streams. Such antibiotic pollutants have non-target effects, raising the general rates of mutation, recombination, and LGT in all the microbiome, and simultaneously providing the selective force to fix such changes. This has the consequence of recruiting more genes into the resistome and mobilome, and of increasing the overlap between these two components of microbial genomes. Thus the human use and environmental release of antibiotics is having second order effects on the microbial world, because these small molecules act as drivers of bacterial evolution. Continued pollution with both xenogenetic elements and the selective agents that fix such elements in populations has potentially adverse consequences for human welfare. © 2013 Gillings.
Veevers J.J.,Macquarie University
Earth-Science Reviews | Year: 2012
The initial (200-175 Ma) breakup of Pangea was marked by the emplacement of the Large Igneous Provinces (LIPs) of Karoo-Ferrar-SE Australia (KFS) in the back-arc of Panthalassan subduction and by the Central Atlantic Magmatic Province (CAMP) between Africa and the Americas. Seafloor spreading 190-180. Ma (Stage 1) about the CAMP split Pangea into northern (Laurasia) and southern (Gondwanaland) parts. Subsequent stages at 167 Ma (2), 147 Ma (3), 130 Ma (4), 118 Ma (5), and 83 Ma (6) split conjugate Africa, South America, India, Australia, and Zealandia from Antarctica. Here I review the reconstruction of Antarctica in Gondwanaland. First, seafloor spreading is unwound to re-unite the continent-ocean boundaries (COBs), then the extended (rifted) crust about the suture is restored to its original thickness. A comprehensive review of the U-Pb zircon geochronology of the reconstructed margins of Antarctica and its conjugates shows that certain coeval structures are aligned across the suture. Cross structures of high-order spatial continuity and age correlation are the Lambert-Mahanadi Rift, Pranhita-Godavari-Robert Glacier trend, Gawler-Adélie Craton, and western part of the Gondwanide Fold Belt. Cross structures of high-order age correlation but low structural continuity or alignment are, from Africa to Antarctica, the East African-Antarctic Orogen, the Natal and Maud Belts, the Umkondo Group-Ritscherflya Supergroup and LIP, and the Kalahari-Grunehogna Craton; from Antarctica to Zealandia, the Ross-Western and Amundsen-Eastern Provinces; and from Africa through Antarctica to Australia the KFS LIP. © 2011 Elsevier B.V.
Stevenson R.J.,Macquarie University
Psychological Bulletin | Year: 2014
The brain binds inputs from multiple senses to enhance our ability to identify key events in the environment. Understanding this process is based mainly on data from the major senses (vision and audition), yet compelling examples of binding occur in other domains. When we eat, in fact taste, smell, and touch combine to form flavor. This process can be so complete that most people fail to recognize that smell contributes to flavor. The flavor percept has other features: (a) it feels located in the mouth, even though smell is detected in the nose and taste on the tongue, and (b) it feels continuous, yet smell is delivered in pulses to the nose during eating. Furthermore, tastes can modify smell perception and vice versa. Current explanations of these binding-related phenomena are explored. Preattentive processing provides a well-supported account of taste-to-tongue binding. Learning between taste and smell can explain perceptual interactions between these senses and perhaps localization of smell to the mouth. Attentional processes may also be important, especially given their role in binding the major senses. Two are specifically examined. One claims that the failure to recognize smell's role in flavor stems from the role of involuntary attention's "defaulting" to the mouth and taste (i.e., binding by ignoring). Another claims that taste and smell form a common attentional channel in the mouth, in effect becoming one sense. Except for preattentive processing, the mechanisms involved in flavor binding differ markedly from those proposed for the major senses. This distinction may result from functional differences, with flavor supporting future food choice but not current identification. © 2013 American Psychological Association.
McCarthy-Jones S.,Macquarie University
Schizophrenia Bulletin | Year: 2012
Progress in identifying the neural correlates of auditory verbal hallucinations (AVHs) experienced by patients with schizophrenia has not fulfilled its promise to lead to new methods of treatments. Given the existence of a large number of such patients who have AVHs that are refractory to traditional treatments, there is the urgent need for the development of new effective interventions. This article proposes that the technique of neurofeedback may be an appropriate method to allow the translation of pure research findings from AVH-research into a clinical intervention. Neurofeedback is a method through which individuals can self-regulate their neural activity in specific neural regions/frequencies, following operant conditioning of their intentional manipulation of visually presented real-time feedback of their neural activity. Four empirically testable hypotheses are proposed as to how neurofeedback may be employed to therapeutic effect in patients with AVHs. © 2012 The Author.
Rapee R.M.,Macquarie University
Journal of Child Psychology and Psychiatry and Allied Disciplines | Year: 2013
Background: There are few evaluations of very early intervention for the prevention of internalising disorders and those that exist generally evaluate outcomes to a maximum of 12 months. The current study evaluated the very long term effects (11 years) of a brief internalising prevention program presented to parents of preschool aged children. Methods: The original sample comprised 146 preschool-aged children who scored high on measures of inhibited temperament. Half of the parents were given a brief educational program (six-sessions) to assist them to help their children reduce anxiousness. Over 70% of the original sample (n = 103) was assessed for the current study, which occurred when the sample was approximately 15 years. They were assessed on current diagnoses of anxiety and depression, as well as symptoms of anxiety, depression, negative thoughts, and life interference. Results: Compared with controls, girls whose parents had been through the early intervention program showed significantly fewer internalising disorders, maternally reported anxiety symptoms and self-reported life interference, and trends toward lower self-reported anxiety symptoms and self reported thoughts of loss and failure. Boys showed few differences. Conclusions: A brief early intervention program delivered to parents of preschool-aged children who are at risk for later internalising distress shows lasting benefits for girls into the high-risk period of middle adolescence. Given the low costs associated with this program, these results show promise for strong public health benefits. © 2013 The Authors. Journal of Child Psychology and Psychiatry © 2013 Association for Child and Adolescent Mental Health.
Fryirs K.,Macquarie University
Earth Surface Processes and Landforms | Year: 2013
The concept of the sediment delivery problem was introduced into the literature in 1983 by Des Walling. This concept describes how only a fraction of sediment eroded within a catchment will reach the basin outlet and be represented as sediment yield, and that sediment storage mechanisms operating within a catchment explain this discrepancy. Since this paper was published, geomorphologists have been examining in great detail the fate of sediment eroded from the landsurface, and the pathways and timeframes of sediment transport and storage in catchments. However, to fully understand the internal dynamics of sediment flux requires a 'fresh look at the sediment delivery problem'. A framework is required that can incorporate the various processes involved in sediment movement from source areas through a basin to its outlet, and can take account of the spatial distribution of, and timeframes over which, these processes operate. This paper presents a conceptual framework for analysis of catchment (dis)connectivity that incorporates both spatial and temporal variability in the operation of the sediment cascade. This approach examines where blockages occur to disrupt these longitudinal, lateral and vertical linkages in catchments. Depending on the position of blockages (termed buffers, barriers and blankets), and their sediment residence time, various parts of a catchment may be actively contributing sediment to the sediment cascade and be switched on, or inactive and switched off. This paper discusses how such a framework can be used to model response times to disturbance and explain the manifestation of geomorphic change in catchments. The paper then highlights challenges geomorphologists face in applying such a framework to understand the internal dynamics of the catchment sediment cascades, and forecast how environmental change might affect the operation of sediment fluxes into the future. © 2012 John Wiley & Sons, Ltd.