Patiāla, India
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Kumar D.,Punjabi University | Kavita,M M Modi College | Singh K.,Punjabi University | Verma V.,Government of Punjab | Bhatti H.S.,Punjabi University
Digest Journal of Nanomaterials and Biostructures | Year: 2014

Carbon nanohorns represent a largely unexplored carbon allotrope within the family of fullerenes and carbon nanotubes. There are three critical points that differentiate carbon nanohorns (CNHs) from carbon nanotubes (CNTs), namely, i)purity, due to the absence of any metal nanoparticles during production, ii) heterogeneous surface structure, due to highly-strained conical-ends, and, iii) aggregation in spherical superstructures, typically ranging between 50-100 nm. In the present investigation single wall carbon nanohorns have been synthesized by submerged arc method followed by hydroxyl and carboxylic addent functionalization using high speed vibration method to make them water soluble. Crystallographic, topographic and morphological analyses of pristine and water soluble SWCNHs have been studied via powder X-ray diffraction, field emission scanning electron microscope, high resolution transmission electron microscope and atomic force microscope respectively. UV-Vis. absorption, Raman spectroscopy, thermogravemetric analysis, X-ray photo electron spectroscopy and Fourier transform infra-red spectroscopic studies have been carried out for the functionalization confirmation. Optical, quantitative and qualitative analysis of the pristine and functionalized single wall carbon nanohorns (SWCNHs) have been conceded via energy resolved and time resolved photoluminescence and energy dispersive X-ray spectroscopic studies respectively. Spectroscopic studies confirm the formation of good quality pristine and functionalized SWCNHs with hydroxyl and carboxylic group addent Spectroscopic studies confirm the formation of good quality pristine and water soluble SWCNHs. The presented method demonstrated its remarkable potentiality in large-scale production of SWCNHs with good purity. Structural analyses of synthesized and functionalized SWCNHs have been studied using Brunauer-Emmett-Teller Surface area analysis Barrett-Joyner-Halenda pore size and volume analysis Technique. © 2014, Inst Materials Physics. All rights reserved.


Sethi G.K.,M M Modi College | Sethi G.K.,Punjabi University | Bawa R.K.,M M Modi College | Bawa R.K.,Punjabi University
Advanced Materials Research | Year: 2012

Text data present in images contains useful information and its extraction involves detection, localization, extraction, enhancement and recognition. However, the problem is challenging due to fact that text can have various styles, size, orientations, alignments, effect of lighting conditions. While a large number of techniques have been proposed in the past for extracting text from images and video frames for foreign languages, not much research has been carried out for Indian languages. The purpose of this paper is to review various algorithms for the problem for foreign as well as for the for the Indian languages. © (2012) Trans Tech Publications, Switzerland.


Kaur B.,Sant Longowal Institute of Engineering And Technology | Parmar A.,M M Modi College | Kumar H.,Sant Longowal Institute of Engineering And Technology
Current Organic Chemistry | Year: 2012

In view of the unique properties, like high solubility in most of the organic solvents, poor complexing ability, low charge density, stability under mild conditions and high electronegativity, transition metal perchlorates have been found to be highly effective catalysts/reagents in wide variety of functional group transformations leading to the synthesis of large number of important organic compounds. This review presents the recent applications of important transition metal perchlorates as safe catalysts/reagents for organic functional group transformations. © 2012 Bentham Science Publishers.


Kaur B.,Sant Longowal Institute of Engineering And Technology | Parmar A.,M M Modi College | Kumar H.,Sant Longowal Institute of Engineering And Technology
Synthetic Communications | Year: 2012

A greener and more efficient protocol for the synthesis of 12-aryl or 12-alkyl-8,9,10,12-tetrahydrobenzo[a]xanthen-11-one derivatives has been developed via one-pot, three-component reaction of aromatic aldehydes, 2-naphthol, and 1,3-cyclohexadione or 5,5-dimethyl 1,3-cyclohexadione using manganese perchlorate hydrate as a catalyst under ultrasonic irradiation. Good yield, shorter reaction time, simple workup procedure, and milder reaction conditions make this protocol efficient and environmentally benign. ©Taylor & Francis Group, LLC.


Kumar K.,M M Modi College | Kaur J.,M M Modi College | Walia S.,M M Modi College | Pathak T.,M M Modi College | Aggarwal D.,M M Modi College
Leukemia and Lymphoma | Year: 2014

L-asparaginase (L-ASNase) is an enzyme used most effectively in the treatment of acute lymphoblastic leukemia (ALL) for more than 30 years. It catalyzes the hydrolysis of amino acid L-asparagine to aspartic acid and ammonia, which leads to cell death. Clinical trials have been conducted using L-ASNase in combination with other drugs and radiotherapy, which have led to great success in the treatment of ALL. Treatments consist of induction therapy and central nervous system therapy. The achievement of complete remission in patients is associated with a few side-effects of using L-asparaginase, including pancreatitis, coagulation abnormalities and allergic reactions. Sometimes tumor cells may develop resistance to L-ASNase. To overcome these difficulties, the drug is modified by pegylation or immobilization, and also treatment protocols can be modified to increase the efficiency of the drug. © 2014 Informa UK, Ltd.


PubMed | M M Modi College
Type: Journal Article | Journal: Recent patents on inflammation & allergy drug discovery | Year: 2016

Tuberculosis is a major public health concern. The present article reviews the current updates on the usage of nanoparticles against tuberculosis and recent patents that could develop into novel therapeutics available to the clinical armamentarium for the TB management. The drug delivery systems involving nanoparticles are suitable against chronic diseases such as tuberculosis. Polymers in many forms like liposomes, dendrimers, Nanoemulsions can be used as synthetic and natural carriers for first line and second line drugs employed for chemotherapy. Not only are the drugs sustainably released in organs and plasma, but also their dosages as well as adverse effects have been reduced, the drug interaction has increased and the drug resistant bacteria have been targeted. The hurdles in the development of anti-tuberculosis have made Nano medicines to act as a silver lining.

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