Esimova A.,M. Auezov South Kazakhstan State univesrity |
Mutaliyeva B.,M. Auezov South Kazakhstan State univesrity |
Madybekova G.,South Kazakhstan State pedagogical institute |
Narymbayeva Z.,M. Auezov South Kazakhstan State univesrity |
And 2 more authors.
Life Science Journal | Year: 2013
Flora of Republic of Kazakhstan have more than 6000 species of medicinal plants, among of which the plant Alhagi Pseudalhagi are the object of fixed attention as a source of essential oil, flavonoids, steroids, vitamins, organic acids, tannin, etc., possessing by wide spectrum of biological activity. Development of methods separation from it the individual compounds, that can be used as a raw material for more efficiency new biological substances, are the most perspective in the present time. In this work are investigated processes of electrodimerization and cross oxidation for obtainment the 8 new compounds based extracted flavonoids. This article contain data of fulfillment of dimerization processes with purpose of obtainment with maximum yield the dimmers based on Oroxyline, 3- Methylquercetine, Isoramnetine and Kemipherid - flavonoids, allocated from Alhagi pseudalhagi, as well as results of investigation of physiological activity of obtained products. The most optimal medium, optimal parameters have been established for effective dimerization process conducting where maximal yield of synthesized compounds are registered. Also, medicobiological testing, implemented in the laboratory of Tumor Radiobiology into Kazakh Scientific Research Institute of Oncology and Radiology, revealed high antiradiation activity of Oroxiline-7-0-7- Glaucinide.