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Roanoke, VA, United States

Grant
Agency: Department of Defense | Branch: Navy | Program: SBIR | Phase: Phase II | Award Amount: 1.06M | Year: 2015

The outer cable strands used to tow the AQS-20A from the RMMV are made from Nitronic 50, an austenitic stainless steel that, under normal circumstances, exhibits excellent corrosion resistance and strength over a wide temperature range. Unfortunately, the cables are experiencing early life corrosion problems due to salt water deposit buildup that occurs over repeated operations and subsequent system stowage. To achieve the corrosion and abrasion resistance necessary for the AQS-20A tow cable, Luna is collaborating with Lockheed Martin to develop a hydrophobic watershedding coating that is mechanically durable, optically transparent, and easy to apply. Numerous accomplishments were made in the Phase I effort that demonstrated the excellent performance of Lunas coating system. Coatings were formulated that provided excellent abrasion resistance, high flexibility, optical transparency, and good corrosion protection of coated Nitronic 50 flat substrates, as well as actual tow cable test articles. In the Phase II, Luna will further improve performance and processing of the hydrophobic coating, validate its use as a robust and cost-effective solution for the RMS tow cable corrosion problem, and transition an application process for implementation testing.


Grant
Agency: Department of Defense | Branch: Army | Program: SBIR | Phase: Phase II | Award Amount: 462.62K | Year: 2016

The U.S. Army is currently developing mobile wastewater treatment solutions reducing the need for wastewater removal from field-forward and tactical bases. Treatment process verification measurements are required to satisfy EPA regulations for the discharge of wastewater with common water quality assessments including fecal coliform load, biochemical and chemical oxygen demands, and total organic carbon. Using standard analytical techniques to monitor these measures of water quality typically requires a combination of lengthy test durations, technical expertise, sensitive instrumentation, and production of hazardous wastes. Leveraging experience with water analysis, fecal coliform quantification assays, and encapsulated microbe based sensors, Luna Innovations has designed and established feasibility of an automated platform for analysis of each measure in near real-time with minimal operational requirements or expertise. During the Phase II program proposed herein, Luna will include integration of chemical oxygen demand and total organic carbon analyses, fabricate prototype systems relying on optical interrogation of our sensor components, and test and validate the system against standard methods.


Grant
Agency: Department of Defense | Branch: Navy | Program: SBIR | Phase: Phase II | Award Amount: 972.38K | Year: 2016

Condition-based monitoring has the potential to significantly reduce operating costs for the U.S. Navy through enhanced maintenance scheduling and reduction in unnecessary inspections / overhauls. Embedded sensors provide monitoring capabilities for data acquisition, analysis and transmission when sufficient power is available through hardwired power, battery, or energy harvesting strategies. There has been a recent surge in research for sensor nodes powered by energy harvesters, however most applications are limited to low-frequency, low-bandwidth applications. There is significant interest in developing new sensing concepts that provide continuous monitoring of high-frequency transient events indicative of failures in hydraulic pumps, actuator/valve systems, and bearings for the U.S. Navy. Luna proposes a new paradigm in how embedded sensors are designed and deployed with energy harvesting / management as a central design component. The proposed approach focuses on four principal functionalities of the sensor node: 1) continuous signal monitoring, 2) self-powered triggering, 3) low-power acquisition / analysis, and 4) multi-tiered power management. The feasibility of this comprehensive design approach has been demonstrated through the Phase I program, and will evolve into a deployable, self-powered condition monitoring system through Phase II development efforts.


Grant
Agency: Department of Defense | Branch: Defense Advanced Research Projects Agency | Program: SBIR | Phase: Phase II | Award Amount: 1.50M | Year: 2015

Special Operations Forces that are deployed in austere areas in the AFRICOM and PACOM are associated with an increased risk of envenomation. Current treatment uses species-specific or polyvalent antivenins that are generated from the sera of animals immunized with whole venom, necessitating the correct identification of the venomous species and continuous injection of large volume of antibodies at an ICU-capable medical facility with increased risk of life-threatening complications. There is a clear capability gap to protect deployed soldiers against venom exposure. Luna proposes to develop bioinspired synthetic nanoparticles as broad-spectrum antidotes with antibody-like affinity and improved toxin-neutralizing capacity. The technical feasibility was demonstrated by rational design, synthesis, and in vitro testing of nanoparticles for five subclasses of venom toxins in the Phase I. Phase II effort will focus on optimize nanoparticles to achieve broad spectrum protection against whole venoms for at least one particular United States Armed Forces Command regions. The Phase II will thoroughly evaluate the efficacy, safety and PKPD of nanoparticle antidote and these IND-enabling preclinical studies will prepare for an IND application.


Grant
Agency: Department of Defense | Branch: Defense Advanced Research Projects Agency | Program: STTR | Phase: Phase II | Award Amount: 1000.00K | Year: 2015

The ability to rapidly detect and identify infectious organisms is critical for the accurate diagnosis of seasonal and sporadic outbreaks, emerging pathogens and agents of bioterrorism. Accurate detection requires high quality biological specimens, which

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