Austin, TX, United States
Austin, TX, United States

Luminex Corporation is a biotechnology company based in Austin, Texas, with offices in Australia, Toronto and the Netherlands. Luminex develops, manufactures and markets proprietary biological testing technologies with applications throughout the life-science industry. Patrick J. Balthrop, Sr. has served as Luminex's President and Chief Executive Officer since May, 2004. Luminex was recently recognized by Forbes magazine as one of the top 25 fastest growing technology companies in the US. Wikipedia.


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Cartridges for the isolation of a biological sample and downstream biological assays on the sample are provided, as are methods for using such cartridges. In one embodiment, a nucleic acid sample is isolated from a biological sample and the nucleic acid sample is amplified, for example by the polymerase chain reaction. The cartridges provided herein can also be used for the isolation of non-nucleic acid samples, for example proteins, and to perform downstream reactions on the proteins, for example, binding assays. Instruments for carrying out the downstream biological assays and for detecting the results of the assays are also provided.


Patent
Luminex Corporation | Date: 2016-07-18

Methods and compositions for assays using catalytic DNA (e.g., that can cleave substrate nucleic acid sequences) are provided.


Patent
Luminex Corporation | Date: 2017-04-26

Lyophilized biological reagents, such as enzymes (e.g., PCR reagents) and antibodies, are provided that include a wax component. Thus, in some aspects, a method is provided for storing a biological reagent comprising formulating the reagent into a lyophilized composition including a wax component. Methods for using such lyophilized reagents are likewise provided.


Patent
Luminex Corporation | Date: 2017-02-08

Fluid storage containers and analysis cartridges for use in assay processes are presented. In addition, systems comprising such storage containers and analysis cartridges and methods of using such containers and cartridges are presented as well. In specific embodiments, fluid storage containers are configured to be coupled to analysis cartridges in a first stage and a second stage.


Patent
Luminex Corporation | Date: 2017-03-10

Apparatuses for preparing a sample are disclosed herein. The apparatuses include a chamber, a first valve at least partially disposed in the first chamber, a second valve at least partially disposed in the first chamber, and a pump comprising an actuator and nozzle.


Patent
Luminex Corporation | Date: 2017-03-03

The present invention provides methods and systems for real-time measurements of PCR with multiplexing capability. Certain embodiments relate to methods and systems that use fluorescently encoded superparamagnetic microspheres for the immobilization of amplification products during the PCR process, and an imaging chamber of a measurement device that is also capable of controllable thermal cycling for assisting the PCR process.


Methods and compositions for the detection and quantification of nucleic acids are provided. In certain embodiments, methods involve the use of cleavable probes that comprise a ribonucleotide position that is susceptible to endoribonuclease (e.g., RNase H) cleavage in the presence of target nucleic acid molecules. Probes of the embodiments may also comprise non-natural nucleotide linked to a reporter and/or quenching moiety.


Patent
Luminex Corporation | Date: 2017-04-26

Methods and systems for magnetic mixing. Particular embodiments relate to applying a magnetic field to move a magnetically responsive component in a chamber.


Patent
Luminex Corporation | Date: 2016-08-10

A parallel preceding system for processing samples is described. In one embodiment, the parallel processing system includes an instrument interface parallel controller to control a tray motor driving system, a close-loop heater control and detection system, a magnetic particle transfer system, a reagent release system, a reagent pre-mix pumping system and a wash buffer pumping system.


Patent
Luminex Corporation | Date: 2016-03-15

Methods and devices for forming droplets are provided. In certain embodiments, the methods and devices form droplets having different diameters.

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