Jamshoro, Pakistan
Jamshoro, Pakistan
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Das C.,Unit I | Sathio S.N.,NIVCD | Rani S.,LUMHS
Medical Forum Monthly | Year: 2017

Objective: To determine the frequency of the factors leading to meconium aspiration syndrome in neonates. Study Design: Descriptive case series study. Place and Duration of Study: This study was conducted at the Neonatal Unit of the Department of Pediatric Medicine, Sheikh Zaid Postgraduate Medical Institute Lahore from 02-08-2013 to 2-02-2014 Materials and Methods: A total of 180 patients were selected for this study. After verbal consent for participating in the study mothers were inquired for factors leading to meconium aspiration syndrome like post maturity and cesarean section with detailed history including date of last menstrual period and mode of delivery and filled in predesigned proforma. Results: There were 101 (56.1%) male and 79 (43.9%) female patients. Neonates delivered with cesarean section were 73 (40.6%), 85 (47.2%) patients had post maturity and 7 (3.9%) patients had IUGR. There were 13 (7.2%) patients had pneumothorax and mortality was recorded in 8 (4.4%) patients. Conclusion: Cesarean section, post maturity and IUGR are important risk factors, frequently associated with meconium aspiration syndrome.

Memon S.,LUMHS | Memon A.G.,GMMMC | Sachdewani R.,LUMHS
Medical Forum Monthly | Year: 2017

Objective: To assess the frequency of elevated C reactive protein in patients those were admitted in the cardiology department after diagnosis of myocardial infarction. Study Design: Cross sectional study. Place and Duration of Study: This study was conducted at the Department of Cardiology, Liaquat University Hospital Hyderabad from October 2015 to march 2016. Materials and Methods: In this study all the patients with diagnosis of MI were selected. Blood samples were drawn and send to the hospital laboratory to assess the CRP levels in all selected cases. On the collection of the reports CRP levels were noted. Data regarding age, gender, types of MI and levels of CRP were recorded in the proforma. Results: Total 62 cases were incorporated in the study; mean age of the study participants was 46.5+6.24 years. Male gender was found in the majority 74.19%, while female were 26.81%.Typical chest pain was most common presentation in 88.70% of the cases, breathing difficulty was noted in 72.58%, sweeting, nausea/vomiting, palpitation, syncope and others were found with percentage of 56.45%, 45.16%, 24.19%, 19.35% and 32.25% respectively. Elevated CRP level was found in 73.58%, while 26.42% cases were with normal CRP level. Conclusion: In the conclusion of this study elevated CRP level was most frequent in patients with acute MI. This may due to diabetic and hypertensive patients. More research is needed especially in diabetic and hypertensive patients.

Mohammed A.T.,LUMHS | Behan R.B.,LUMHS | Laghari Z.H.,LUMHS
Medical Forum Monthly | Year: 2017

Objective: The objective of this study was to find out the frequency of perforated appendicitis and reasons of perforated appendicitis at tertiary care Hospital. Study Design: Cross sectional study Place and Duration of Study: This study was conducted at the Department Surgery, LUMHS from February 2014 to January 2015 Materials and Methods: Total 107 patients were admitted in the surgery ward, out of those 75 were underwent appendectomy. All the patients who underwent appendectomy were included in the study after taking informed consent while other patients and patients having co morbidity were excluded from the study. All the information regarding their presenting symptoms, cause of appendectomy etc was recorded on self-designed proforma. Data was entered on SPSS version 16. Results: Mean age of the patients was 35+- 2.09. 21(28%) patients belong to age group of <30 years, 33(44%) belonged to age group of 30-40 years and 15(20%) were from age group of 41-50 years. Majority of the patients i.e 56(74.66%) were males while 19(25.33%) were females. In this study, 15(20%) patients had perforated appendicitis, 48(64%) had inflamed appendicitis while 10(13.33%) had gangrenous appendix and 2(2.66%) had normal appendix. In our study, the most common cause of perforated appendix was misdiagnosed by doctors as seen in 6(40%) patients followed by delay in reaching hospital seen in 4(26.66%) , while 3(20%) were reluctant for surgery. 45(60%) patients had presented with pain in right iliac fossa, 16(21.33%) had fever and 10(13.33%) had nausea. Conclusion: We concluded that frequency of perforated appendicitis is 20% and its main associated factors are; misdiagnosis by general practitioners and delay in reaching the Hospitals where surgeons and surgical facilities are available.

Memon A.G.,LUMHS | Sachdewani R.,GMMMC | Memon S.,LUMHS
Medical Forum Monthly | Year: 2017

Objective: To determine the frequency of arrhythmias in patients admitted with Acute Myocardial Infarction. Study Design: Observational study Place and Duration of Study: This study was conducted at the Department of Cardiology, LUH Hyderabad from January 2015 to December 2016. Materials and Methods: Patients with Acute MI, both genders were selected for the study. Acute MI and arrhythmia's diagnosis was assessed on the basis of history, electrocardiography and arrhythmias, and significantly cardiac enzymes (biomarkers) elevation particularly Troponins. Finally arrhythmias were assessed and all the data was recorded in the proforma. Results: In our study 90 patients were selected, patients mean age was 55.66±10.4 years male gender was most common 69(76.6%). Acute anterior wall MI and Acute inferior MI were found most common as 27.77% and 23.33%. Over all arrhythmias was found 83.40%. According to type of arrhythmias VT, VF, Atrial Fibrillation and CHB were found most common as 26.66%, 13.34%, 14.66% and 14.66% respectively. Conclusion: We concluded that Arrhythmias is most frequent in patients with MI, and found almost all in cases.

Junejo M.A.,Liaquat University of Medical & Health Sciences | Tahir S.M.,LUMHS | Behan R.B.,LUMHS
Journal of the Liaquat University of Medical and Health Sciences | Year: 2017

BACKGROUND: The common work related musculoskeletal disorders (WRMDs) among medical profession are pain in neck, elbow, shoulder wrist and back. Sonographers are more vulnerable to develop WRMDs as their work demands series of awkward repetitive movements. OBJECTIVE: To determine the prevalence of work related musculoskeletal disorders (WRMDs) and to identify factors that may contribute to musculoskeletal disorders among sonologists of Sindh Province Pakistan. METHODOLOGY: This questionnaire based study conducted at the Department of Radiology, Liaquat University of Medical & Health Sciences. The target population chosen for this study was sonologists from the Sind province of Pakistan. SPSS used to analyze the data, results presented as frequency for categorical variables and as mean for continuous variables. To identify predictor variable for WRMDs, multiple bivariate regression analysis was performed, the level of significant was set at P <0.05. RESULTS: Among 145 participants, 53.80% were University employed, while 56.54 were performing ultrasonography up to 10 hours. The prevalence of WRMDs disorder in this series was 75.17%, the mean duration of symptoms was 30.48 months. 45.9% reported it as severe. WRMDs were more prevalent and severe in those doing scanning of both abdomen and Obstetric. The Low back ache is the most common site of WRMDs found in this series (53.21%, n=58), followed by neck ache (24.77%) wrist joint (8.25%), finger (7.33%) and shoulder (6.42%). The result of bivariate analysis showed that severity of WRMDs correlated statistically significantly with primary area of expertise, duration of WRMDs, working experience and working hours. CONCLUSION: The prevalence of WRMDs and its severity is significantly high among Sonographers of Sindh province. © 2017, Liaquat University of Medical and Health Sciences. All rights reserved.

Jamal B.,University of Sindh | Shaikh F.,LUMHS | Memon M.Y.,LUMHS
Journal of the Liaquat University of Medical and Health Sciences | Year: 2017

OBJECTIVES: Pre-eclampsia is hypertensive and multi-system related disorder of pregnancy. It has frequently labeled as “disease of theories”. 5- 10% of pregnancies complicated due to pre-eclampsia and it is most common health problem worldwide. This study intended to estimates the copper, zinc and magnesium levels in patients with pre-eclampsia. METHOD: Total eighty subjects were included in the present study, from which 40 voluntaries were normotensive healthy pregnant women (controls), 40 were pre-eclamptic patients (cases). The subjects were recruited having symptoms of interest after taking obstetric history, anthropometric and clinical data. After taking informed consent, blood sample collected and stored for biochemical analysis. The serum zinc, copper and magnesium levels were analyzed by Atomic Absorption Spectrophotometer. The study was conducted in biochemistry department during period of eight months from October 2015 to June 2016. RESULTS: Total eighty subjects were included in present study. The trace elements decreased and shows significant difference between control healthy pregnant and pre-eclamptic women (p<0.05). The mean difference of copper (0.15±0.07), zinc (2.94±0.45) and Mg++ (0.15±0.09) mg/dl for the cases group and for control group copper was (0.20±0.03), zinc (5.11±0.21) and Mg++ (2.17±0.21) mg/dl respectively. CONCLUSION: Trace elements are essential for the healthy pregnancy, suppressed concentration of serum Zinc, Copper and Magnesium may put forward the possible involvement in the pathology of pre-eclampsia. The aim of this study was to protects the mothers as well as her coming newborn from such life threating disease. © 2017, Liaquat University of Medical and Health Sciences. All rights reserved.

Shaikh M.A.,LUMHS | Memon I.,LUMHS | Ghori R.A.,LUMHS
Journal of the Pakistan Medical Association | Year: 2010

Objective: To analyze the frequency and causes of anaemia in systemic lupus erythematosus (SLE) patients attending in department of medicine at tertiary care hospitals. Methods: This retrospective, descriptive and analytical study was planned to analyze the frequency and causes of anaemia in SLE patients attending the department of medicine at (MMC) and (LUMHS) hospitals during the period of Jan 2006 to Nov 2008. The criteria used in this study were from the American College of Rheumatology. Investigations recorded were blood complete picture, absolute values, peripheral smear, and reticulocyte count in all patients of anaemia. These investigations were necessary to analyse the cases of anaemia in SLE. All investigations were not done in all cases. Patients with hypochromic microcytic anaemia were advised to have serum iron and ferritin levels, seven patients with macrocytic anaemia were advised to have direct and indirect coomb's test, LFTs, serum LDH, serum B12 and folate levels. Patients with normochromic and normocytic anaemia were considered to have anaemia of chronic disease. Bone marrow aspiration and Hb electrophoresis were done in two patients with anaemia of chronic disease. Thirty adult patients were included in this study. Special proforma were prepared to record the information from case sheets of patients including basic information, symptomatology and laboratory investigations. Severity and various types of anaemias were recorded. Anaemia was graded according to severity, as mild (Hb 10-12 G/dl), Moderate (Hb 8-10 G/dl) and severe (Hb < 8 G/dl). Haemoglobinopathies and other types of anaemias were excluded from study. Results: Thirty adult diagnosed patients of SLE, were included. Their ages ranged from twenty years to fifty years at time of presentation. The mean age ± SD (range) was 28 ± 6.22 (20-50) years and median age was 31 years. Out of thirty patients, twenty seven (90%) were females and three (10%) were males. Twenty eight (93.33%) patients presented with anaemia, 14 (46.66%) patients were of mild anaemia, 8 (26.66%) patients were of moderate grade anaemia and 6 (20%) patients had severe anaemia. Iron deficiency anaemia was found in 9 (30%) patients, 12 (40%) patients had anaemia of chronic disease and 7 (23.33%) patients had haemolytic anaemia, out of theses 7 patients, 5 (16.66%) patients had Coomb's positive haemolytic anaemia. All thirty patients had ANA positive titres >1:80; and nineteen (63.33%) patients had anti ds DNA positive, titres >1:10. Conclusion: Haematologic abnormalities are common manifestations in patients with SLE. Most patients exhibit anaemia at some point during their disease course.

Qadeer-Ul-Hassan Prof.,LUMHS
Medical Forum Monthly | Year: 2014

Objective: To find out frequency and clinical presentation of dry socket in Department of Oral and Maxillofacial Surgery Liaquat University of Medical & Health Sciences, Jamshoro. Study Design: Obseervational study. Place and Duration of Study: This study was carried out at Department of Oral & Maxillofacial Surgery, Liaquat University of Medical & Health Sciences, Jamshoro from Jan 2011 to June 2012. Materials and Methods: Age from 11 to 70 years with both gender groups was included in the study. They were observed for the presence of dry socket. Patients with previous history of two or more days of extraction, pam. sensitivity on gentle probing of the extraction socket and empty/ partially empty socket were included m the study. Data was analyzed using SPSS version-13. Results: Total 2300 extractions were included in study; dry socket was recorded in 66 (3.3%) routine dental extraction except 3rd molars and 598 (26%) surgical& non-surgical extraction of 3rd molar respectively. Majority of the patients belong to 3rd decade of life Conclusion: In oral Surgery practice dry socket is unavoidable, but oral surgeons must identify additional risk factors in patients with particular medical conditions and include this information as a part of the informed consent.

Punjabi S.K.,LUMHS | Habib-ur-Rehman,Abbasi Shaheed Hospital | Ali Z.,Abbasi Shaheed Hospital | Ahmed S.,Abbasi Shaheed Hospital
Journal of the Pakistan Medical Association | Year: 2011

Objectives: To assess the causes and management of Zygomatic bone fractures at Abbasi Shaheed Hospital, Karachi. Methods: This study was carried out at Department of Oral & Maxillofacial surgery Abbasi Shaheed Hospital, Karachi. A total of 82 cases were studied. A detailed history was taken, clinical examination was performed and fractures were confirmed by radiography. Management of fractures was done by using different proposed modalities,suitable for every case. A number of factors, like age of patients, causes of trauma and gender were assessed. Results: The commonest cause of Zygomatic bone fracture was found to be road traffic accident (RTA) 50% (n=41), followed by assault 23.17% (n=19), fall 20.73% (n=17), sports injuries 3.65% (n=3), and others 2.43% (n=2) respectively. Right side (55%) was involved a little more than the left side (45%). Zygomatic bone fracture was more prevalent in age group between 21-30 years, while male to female ratio was 5.30:1. Remote reduction using Gillie's Temporal Approach with and without fixation using bone plates were the commonest management modalities used in this center. Conclusion: The commonest cause of Zygomatic bone fracture was found to be road traffic accident, with the right side fractures being more common. It reveals poor road traffic sense in road users, lack of road safety measures and legislation in our population.

Khaskhelli L.B.,University of Sindh | Memon S.,LUMHS | Goswami P.,LUMHS | Bano S.,LUMHS
Journal of the Liaquat University of Medical and Health Sciences | Year: 2013

OBJECTIVES: To observe and compare gross and histological changes of the placenta of nondiabetic and diabetic mothers. And observe possible changes in the fetal weight of diabetic and non diabetic mothers. STUDY DESIGN: Case control study. PLACE AND DURATION: This study was conducted from June 2009 to July 2010 at the department of Anatomy of Liaquat University of Medical & Health Sciences Jamshoro. The placentae were collected from department of Gynecology & Obstetrics of Liaquat University Hospital. MATERIAL AND METHODS: Eighty freshly delivered placentae were collected forty placentae from diabetic's mothers & forty placentae from parturient belonged to uncomplicated pregnancy (control group). Ages of all parturient were between 17 to 32 years. Fetal outcome and data was recorded. Placentae were measured on a weighing machine graduated in grams and diameter was measured with the help of a measuring tape in centimeters. Approximately five mm piece of from diabetic placenta was taken and processed for histological examination. Fetal weight was also recorded. RESULTS: Morphological examination of placentae showed larger, heavier and more cotyledenous placentae group as compared to controls. Similarly microscopic examination revealed dilated blood vessels, necrotic and degenerative foci in placentae of diabetics as compared to controls. CONCLUSION: Diabetes Mellitus produces profound gross as well as histological changes in placentae which might result in large for date babies because of fetal compromises. A good glycemic control might be a better option for reducing diabetes induced abnormalities.

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