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Sibiu, Romania

The Lucian Blaga University of Sibiu is a university in Romania. It was named after the philosopher, poet, and playwright, Lucian Blaga. It was founded in 1990 with five schools: Letters, History and Law, Medicine, Food and Textile Processing Technology, Engineering and science. Other schools were added later. Wikipedia.

Moulin E.,Charles Sadron Institute | Cormos G.,Charles Sadron Institute | Cormos G.,Lucian Blaga University | Giuseppone N.,Charles Sadron Institute
Chemical Society Reviews | Year: 2012

This tutorial review presents emerging lines of investigations directed towards the development of dynamic combinatorial materials and devices. These can be defined as multi-component chemical systems which, thanks to the reversibility of their interconnections within networks of competing reactions, and thanks to their sensitivity to environmental parameters, aim at performing modular functional tasks by responding to external stimuli. The behaviour of such dynamic materials is by essence more complex than the one produced by their static or single-component counterparts and as such, they hold higher potentialities in terms of information processing and functionality tuning. Key examples are selected here to illustrate the variety of their chemical nature and physical properties which can be implemented for the fabrication of devices as diverse as sensors, ion channels, self-healable materials, mesophases for the controlled release of bioactive compounds, or dynamic functional nanostructures. © 2012 The Royal Society of Chemistry. Source

Chicea D.,Lucian Blaga University
Optoelectronics and Advanced Materials, Rapid Communications | Year: 2010

Nanofluids are suspensions of nano to micrometer sized particles in liquids. A nontypical Dynamic Light Scattering experiment was conducted for measuring the nanoparticles and the aggregates diameter in aqueous suspension. Atomic Force Microscope (AFM) measurements were also carried on and the results are discussed. Source

MihAilA R.-G.,Lucian Blaga University
World Journal of Gastroenterology | Year: 2016

The hepatitis C virus (HCV) infected patients are prone to develop bone marrow or various tissue infiltrates with monoclonal B cells, monoclonal B lymphocytosis or different types of B cell non-Hodgkin's lymphoma (BCNHL), of which the most common are splenic marginal zone BCNHL, diffuse large BCNHL and follicular lymphoma. The association between chronic HCV infection and non Hodgkin's lymphoma has been observed especially in areas with high prevalence of this viral infection. Outside the limitations of some studies that have been conducted, there are also geographic, environmental, and genetic factors that contribute to the epidemiological differences. Various microenvironmental signals, such as cytokines, viral antigenic external stimulation of lymphocyte receptors by HCV antigens, and intercellular interactions contribute to B cell proliferation. HCV lymphotropism and chronic antigenic stimulation are involved in B-lymphocyte expansion, as mixted cryoglobulinemia or monoclonal gammopathy of undetermined significance, which can progress to BCNHL. HCV replication in B lymphocytes has oncogenic effect mediated by intracellular HCV proteins. It is also involved in an important induction of reactive oxygen species that can lead to permanent B lymphocyte damage, as DNA mutations, after binding to surface B-cell receptors. Posttransplant lymphoproliferative disorder could appear and it has a multiclonal potentiality that may develop into different types of lymphomas. The hematopoietic stem cell transplant made for lymphoma in HCV-infected patients can increase the risk of earlier progression to liver fibrosis and cirrhosis. HCV infected patients with indolent BCNHL who receive antiviral therapy can be potentially cured. Viral clearance was related to lymphoma response, fact that highlights the probable involvement of HCV in lymphomagenesis. Direct acting antiviral drugs could be a solution for the patients who did not tolerate or respond to interferon, as they seem to be safe and highly effective. The use of chemotherapy in combination with rituximab for the treatment of BCNHL in patients infected with HCV can produce liver dysfunction. The addition of immunotherapy with rituximab can increase the viral replication, and severe complications can occure especially in patients co-infected with hepatitis B virus or immune immunodeficiency virus, in those with hepatocarcinoma, cirrhosis, or liver cytolysis. But the final result of standard immunochemotherapy applied to diffuse large BCNHL patients with HCV infection is not notably worse than in those without this viral infection. The treatment of patients chronically infected with HCV and having BCNHL is complex and requires a multidisciplinary approach and the risk / benefit ratio of rituximab treatment must be evaluated especially in those with liver cytolysis. © The Author(s) 2016. Published by Baishideng Publishing Group Inc. All rights reserved. Source

Crciunean V.,Lucian Blaga University
Academic Journal of Manufacturing Engineering | Year: 2014

The current objectives to increase the standards of quality and efficiency in manufacturing processes can be achieved only through the best combination of inputs, independent of spatial distance between them. Electronic communication solves the problem of the distance between resources. As a natural consequence, achieving these objectives is solved by virtual production processes. Due to the complexity of these production processes they cannot be mastered without the help of accurate and complex models that reflect real-time evolution and breakdown of aggregate physical and logical actions focused on goals. This paper proposes a linguistic model for building virtual production systems by assembling intelligent elementary actions with a high degree of independence. Thus from a lot of independent actions which we call actions of aggregation, we define an aggregation system of actions capable of generating aggregate production processes. In our model the aggregated production process is a word in a language over the alphabet consisting of actions of aggregation. © 2014, Academic Association for Manufacturing Engineering. All rights reserved. Source

Chicea D.,Lucian Blaga University
UPB Scientific Bulletin, Series A: Applied Mathematics and Physics | Year: 2014

Nanofluids are suspensions of nano to micrometer sized particles in liquids. In a suspension the nanoparticles have a complex movement of both sedimentation and Brownian motion. A computer code to simulate the nanoparticles Brownian motion by individually handling each nanoparticle and an algorithm to assess the time step is described. A simple ansatz to calculate the time step for a specific nanoparticle diameter in an aqueous suspension is presented, as well. Source

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