Patel R.V.,University College London |
Patel R.V.,Great Ormond Street Children Hospital NHS Trust |
Kumar H.,LRI |
More B.,LRI |
BMJ Case Reports | Year: 2013
A previously healthy 6-year-old girl that initially presented with presumed viral gastrointestinal infection for a week and later developed catastrophic primary peritonitis and septic shock requiring resuscitation and emergency exploratory laparotomy without any identifiable intra-abdominal cause of the sepsis and the peritoneal exudates grew group A streptococci. Appropriate antibiotic therapy was instituted and she made a complete recovery. Copyright 2013 BMJ Publishing Group. All rights reserved.
Triantafyllidou D.,VTT Technical Research Center of Finland |
IEEE International Symposium on Personal, Indoor and Mobile Radio Communications, PIMRC | Year: 2010
Delay-based routing is proved to improve the network's round-trip time without enhancing its throughput . The reason is that optimising the end-to-end delay -as any load-based metric- creates route instability which results in packet reordering. This problem is detrimental for TCP. In the present work, we couple delay-based routing with a mechanism that locks, upon each node, the next-hop for each TCP flow, unless that hop becomes unavailable. The routes for future flows are proactively discovered by optimized link-state routing (OLSR) and reside in the node's routing table, so the proposed mechanism is fully distributed. Simulation experiments in static and mobile scenarios for small pedestrian networks show that the use of path-locking in conjunction with delay-based routing alleviates the route oscillations and improves the TCP's throughput. ©2010 IEEE.
Pujolle G.,Pohang University of Science and Technology |
Pujolle G.,University Pierre and Marie Curie |
Al Agha K.,LRI
Lecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics) | Year: 2013
This paper deals with the minimization of energy consumption in mesh access networks. As proposed in 3GPP, future wireless access networks will be based in part on mesh technology. Indeed, as all access points cannot be connected by optic fibers to the core networks, we propose to realize a mesh network to connect altogether hotspots and femtocells. To optimize the energy consumption we have developed a Start-and-Stop mechanism permitting to turn-off all unused physical machines. Moreover, we developed a virtual environment to work with virtual machines instead physical machines. This permits to move virtual resources from one physical point to another one. Finally, we describe the piloting system based on the autonomic paradigm, and associated with a knowledge plane. This piloting system is able to minimize the energy consumption in future mesh access networks. © Springer-Verlag 2013.
Kolpakov R.,Moscow State Pedagogical University |
Kucherov G.,French Institute for Research in Computer Science and Automation |
Kucherov G.,J V Poncelet Laboratory |
Ochem P.,LRI |
Ochem P.,J V Poncelet Laboratory
Information Processing Letters | Year: 2010
The first two authors have shown [1,2] (Kolpakov and Kucherov, 1999, 2000) that the sum of the exponents (and thus the number) of maximal repetitions of exponent at least 2 in a word (also called runs) is linear with respect to the length of the word. The exponent 2 in the definition of a run may seem arbitrary. In this paper, we consider maximal repetitions of exponent strictly greater than 1. © 2010 Elsevier B.V. All rights reserved.
Patel R.V.,University College London |
Patel R.V.,Children Hospital NHS Trust |
Kumar H.,LRI |
More B.,LRI |
BMJ Case Reports | Year: 2014
We present a case of oesophageal atresia with distal tracheo-oesophageal fistula and duodenal atresia, which later on was detected to have cystic variant of biliary atresia. He underwent primacy repair of oesophageal atresia with ligation of distal tracheo-oesophageal fistula and duodenoduodenostomy. He later developed features of obstructive jaundice, and on investigation was diagnosed to have cystic variant of biliary atresia which was initially confused with iatrogenic biliary obstruction. Exploration and operative cholangiogram with biopsy confirmed cystic variant of biliary atresia and underwent successful Kasai procedure. Our case effectively demonstrates a rare triology of foregut atresia without an apparent genetic association. It highlights stepwise systematic management of foregut atresias in this patient and demonstration of cystic variant of biliary atresia. Even though these are rarely seen, still the clinician should be aware of such a possibility and should adopt a multimodality approach to diagnose and an aggressive approach to manage the condition. Copyright 2014 BMJ Publishing Group. All rights reserved.
Faur C.,CNRS LIMSI |
Caillou P.,LRI |
Martin J.-C.,CNRS LIMSI |
Clavel C.,CNRS LIMSI
2015 International Conference on Affective Computing and Intelligent Interaction, ACII 2015 | Year: 2015
Artificial agents are becoming artificial companions, interacting with the user on a long-term basis. This evolution brought new challenges to the affective computing domain, such as designing artificial agents with personalities to the benefits of the user. Endowing artificial agents with personality could help to increase the agent's believability, hence easing the interaction. This paper touches on two questions pertaining to computational personality modeling: 1/ how to produce artificial personalities which can inform personality researchers, whether from computer sciences or psychology and 2/ will behaviors produced by artificial agents be perceived by users as putting the programmed personality across as such. We propose to use a data-driven approach to endow artificial agents with personality, using the regulatory focus theory as a framework. We used machine-learned game strategies, in the form of alternative decision trees computed from human data, to convey the personality of artificial agents. We then tested whether these personalities can be perceived by users after playing a game against these agents. We used two artificial agents as controls: one randomly playing and one with an average / depersonalized strategy. On the one hand, our results show that agents' regulatory focus, when programmed, can be accurately perceived by users. On the other hand, our results also point out that personality will be perceived by users even if the agent's design does not intend to transmit one. © 2015 IEEE.
Hajri H.,LRI |
Bourda Y.,LRI |
Lecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics) | Year: 2015
Personalized applications like recommendation systems or open adaptive hypermedia require to facilitate reuse and interoperability of educational resources. Thus we have to solve the problem of discovering educational datasets and the problem of the fragmented landscape of competing metadata schemas. In this paper, we compare a subset of metadata schemas used by educational datasets obeying the Linked Open Data principles and we propose mappings between them © Springer International Publishing Switzerland 2015.
Nguyen H.N.,LRI |
Poizat P.,French National Center for Scientific Research |
2013 IEEE 24th International Symposium on Software Reliability Engineering, ISSRE 2013 | Year: 2013
Service-oriented engineering is an emerging software development paradigm for distributed collaborative ap-plications. Services are developed independently and are composed to achieve common requirements. Service choreographies define such requirements from a global perspective, based on interactions among a set of participants that are implemented as services. In this paper, we support a reliable data-aware service choreography development process through a dedicated projection. It extracts, from a choreography, a behavioral skeleton for each of its participants. The projection is valuable in a top-down approach, where developers have only to complete the skeletons with some business code in order to get a distributed application that matches the choreography requirements. The projection is also valuable in a bottom-up approach, where the skeletons can act as controllers between reused services in order to enforce the respect of the choreography. Our approach is supported with a tool that can be downloaded or used online. © 2013 IEEE.
News Article | December 1, 2016
With more than 10 years of experience in the field, many successful installations in routine diagnostic pathology labs, LRI Imaging AB is the leading diagnostic digital pathology provider in Sweden. Today, Visiopharm A/S has implemented diagnostic digital pathology at a national scale in Denmark, as well as several other systems in Europe.With a staff of almost 50 digital pathology experts, Visiopharm A/S and LRI Imaging AB are jointly becoming a highly specialized European leader in Diagnostic Digital Pathology solutions. “We are now seeing diagnostic digital pathology take off; and not just in Scandinavia, but in large parts of Europe. An important experience from the last 10 years is that going digital is a major undertaking for the pathology lab. We are excited about this merger, which allow us to offer our joint experience and expertise in helping diagnostic pathology labs going digital - one cost-efficient and risk-free step at a time. Our joint expertise gives us a depth of practical expertise in all critical aspects of digital pathology, allowing us to become a true partner in helping pathology labs both implement and take full advantage of this type of technology”, says Michael Grunkin CEO of Visiopharm Rickard Lindelöf, CEO of LRI Imaging / Visiopharm AB, adds: “For almost a decade we have provided diagnostic digital pathology solutions to Swedish pathology labs. We have done that by integrating best-of-breed solution components. The technology developed by Visiopharm allow us to finally realize the full potential of diagnostic digital pathology: Integrating image analysis in LIS-driven workflows, which is giving pathologists access to validated technology that will improve both data quality and productivity while reducing costs and turnaround times”. “We have been running several large clinical studies using this technology, of which some have already been published. That has allowed us to see firsthand to what extent image analysis, if used in the right way, can give significant improvements in diagnostic data quality. We believe this will have a great impact on patient safety. And we are excited to see such technology integrated in an open end-to-end digital pathology solution. We are convinced that digital pathology will lead to improvements in the patient care and help us cope with the growing case load and complexity all diagnostic labs are experiencing. This will benefit both patients individually and society in general,” says Johan Hartmann, Professor at Karolinska University Hospital. Visiopharm offers a truly open and agnostic end-to-end diagnostic pathology solution with best-of-breed components spanning: 1. Best in class slide scanning technology 2. Viewing technology and pathologist cockpit which is setting new standards regarding speed, simplicity, and design. Open to all commercially available slide formats, and enabled for advanced image analysis 3. Support for a range of image management systems, including pathology PACS and VNA. 4. Patent protected, documented and CE-IVD marked computer aided diagnosis (CAD) software scientifically validated improvements to data quality and productivity in a pathology lab. IVD-APPs are validated for all major reagent providers 5. Fully integrated with local LIS systems , providing LIS-driven workflow solutions. Custom integration to other LIS solutions provided as part of the package. 6. A team of experts with deep practical experience in deploying, integrating and supporting end-to-end digital pathology solutions in the daily routine of a pathology lab 7. Change management services and teams allowing our clients to reap the full benefit of their investment About Visiopharm Visiopharm is a leading provider of quantitative image analysis software and end-to-end Digital Pathology solutions for Hospitals, biopharmaceutical companies and research institutions around the world. Recently, Visiopharm has expanded to include ONCOTOPIX® Diagnostics a robust solution for cancer diagnostics with CE-IVD algorithms for the breast panel, integrated LIS driven workflow, and VirtualDoubleStaining™. Visiopharm’s software is featured in over 900 scientific publications, and is compatible with leading slide scanner manufacturers, data management software, and staining providers. Visiopharm, a privately owned company, is an international business with over 600 licenses placed, with countless users, in more than 30 countries. A growing network of authorized distributors and integration partners support the growth of Visiopharm solutions on several continents including North America, Europe and Asia. About LRI Imaging AB LRI, a privately owned company, with installations in more than 20 laboratories and nearly 50 scanners placed in Sweden and Norway, is a leading provider of digital slide scanning and end-to-end Digital Pathology solutions including macro cameras for hospitals. With more than 30 years of experience in the pathology field LRI has a broad knowledge in laboratory workflow and has been able to successfully expanded its business in a rapidly growing market due to an always open mind to customers’ need and a great portfolio of solutions.
News Article | December 12, 2016
Legal Risk Institute announces the launch of their online training course, Ethical and Practical Duties for Lawyers in The Cyber Age, which is accredited in most US states for continuing legal education credits. Lawyers and legal staff can earn CLEs as they study how critical information and security are to their profession, along with tips on how to avoid problems. Founder and President of Legal Risk Institute (LRI), Michael J. Sacopulos, JD, who has developed this program states, “Many firms don’t realize all of the potential sources for cyber issues from their own staff. As more legal research and documentation takes place online, there are new risks and ethical duties that all attorney’s and their staff should be aware of.” Legal Risk Institute assists attorneys and staff to avoid electronic cyber risks through consulting, training and online courses. This course has been approved for CLEs in 28 states, with additional accreditations expected. Additional videos and resources are also being developed surrounding this subject area. The cyber world raises ethical duties under the Rules of Professional Responsibility. Hackers, malware and ransomware also present risks that could not be appreciated even just a few years ago. “The connectedness of people today through Social Media, Wi-Fi hotspots, and Cloud-based software have forever altered the practice of law,” Sacopulos shared. “Many people don’t realize the vulnerabilities that the convenience of connectedness can open law firms up to. It’s our professional responsibility to keep client information safe, secure and learn how to avoid issues through regular training.” About Michael J. Sacopulos Michael is an accomplished public speaker and author, routinely contributing columns to national medical and legal trade publications, including Bloomberg, Beckers’, and Journal of Legal Medicine, as well as other national mainstream news outlets including Wall Street Journal and Forbes.com. He has also appeared on Fox Business News. Michael graduated magna cum laude from Harvard College before doing graduate work at the London School of Economics. He received a law degree with honors from Indiana University Purdue University Indianapolis. About Legal Risk Institute Legal Risk Institute (LRI) was founded to assist attorneys and law firm administrators mitigate electronic risks and fully understand how the cyber world raises ethical duties under the Rules of Professional Responsibility. To this end, LRI develops courses and support materials for clients as well as provides professional speakers and tailored training for law firms. Learn more at http://www.legalriskinstitute.com