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Paris, France

Grant
Agency: Cordis | Branch: H2020 | Program: CSA | Phase: GERI-1-2014 | Award Amount: 1.57M | Year: 2015

Hypatia will bring about lasting change in the way schools, science museums, research institutions and industry engage teenage girls in STEM across Europe. Bringing these stakeholders together with gender experts and teenagers themselves, Hypatia will develop, pilot and disseminate a unique modular toolkit of activities and guidelines for engaging teenagers in STEM in a gender-inclusive way. These innovative activities, based on existing European good practices, will be implemented in 14 EU countries and further afield, in schools, science museums and by institutions in research and industry, thanks to hubs of stakeholders strengthened through the project. The activities will have a central focus on gender-inclusive ways of communicating STEM, empowering teenage girls and exploring the range of skills that are needed for the great variety of STEM studies and careers open to young people. The Hypatia hubs will provide a sustainable basis for these activities to be carried out on the long term, with a focus on dissemination through networks and stakeholder engagement allowing the project impact to multiply.


Grant
Agency: Cordis | Branch: H2020 | Program: RIA | Phase: PHC-33-2015 | Award Amount: 30.12M | Year: 2016

The vision of EU-ToxRisk is to drive a paradigm shift in toxicology towards an animal-free, mechanism-based integrated approach to chemical safety assessment. The project will unite all relevant disciplines and stakeholders to establish: i) pragmatic, solid read-across procedures incorporating mechanistic and toxicokinetic knowledge; and ii) ab initio hazard and risk assessment strategies of chemicals with little background information. The project will focus on repeated dose systemic toxicity (liver, kidney, lung and nervous system) as well as developmental/reproduction toxicity. Different human tiered test systems are integrated to balance speed, cost and biological complexity. EU-ToxRisk extensively integrates the adverse outcome pathway (AOP)-based toxicity testing concept. Therefore, advanced technologies, including high throughput transcriptomics, RNA interference, and high throughput microscopy, will provide quantitative and mechanistic underpinning of AOPs and key events (KE). The project combines in silico tools and in vitro assays by computational modelling approaches to provide quantitative data on the activation of KE of AOP. This information, together with detailed toxicokinetics data, and in vitro-in vivo extrapolation algorithms forms the basis for improved hazard and risk assessment. The EU-ToxRisk work plan is structured along a broad spectrum of case studies, driven by the cosmetics, (agro)-chemical, pharma industry together with regulators. The approach involves iterative training, testing, optimization and validation phases to establish fit-for-purpose integrated approaches to testing and assessment with key EU-ToxRisk methodologies. The test systems will be combined to a flexible service package for exploitation and continued impact across industry sectors and regulatory application. The proof-of-concept for the new mechanism-based testing strategy will make EU-ToxRisk the flagship in Europe for animal-free chemical safety assessment.


The present invention relates to a cosmetic process for making up or for the non-therapeutic care of keratin fibres, comprising the application to the keratin fibres of a cosmetic composition containing at least one compound or a mixture of compounds, which, when the composition is brought to a temperature of greater than or equal to 40 C., confers on said composition a threading nature dmax of greater than or equal to 5 mm, said composition being, prior to, simultaneously with or subsequent to its application, brought to a temperature of greater than or equal to 40 C. The invention also relates to a packaging and application assembly for a composition for making up and/or for the care of keratin fibres, comprising:


The invention relates to a hair styling appliance ( According to the invention, the greatest width l


A cosmetic process for making-up and/or caring for skin and/or lips, includes the application to skin and/or lips of a cosmetic composition including, in a physiologically acceptable medium, at least one supramolecular polymer and at least one hydrophobic film-forming polymer. Particular compositions may be used in the process.

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