Szamatowicz M.,Lomza State University of Applied Sciences |
Szamatowicz M.,Medical University of Bialystok
Przeglad Menopauzalny | Year: 2016
Osteoporosis is a very common disease among women. It is frequently called a silent epidemic and, due to its impact on osteoporotic fractures with high morbidity and mortality, also a silent killer. There are a number of significant risk factors for osteoporosis, some of them very strongly related to the functioning of the reproductive system. These include menstrual irregularities, premature ovarian failure, early natural or surgical menopause, a high number of pregnancies, and long-term breast-feeding. Hence, there is every reason to include gynaecologists in the multidisciplinary team striving to cope with this dreadful disease. Calculation of the 10-year fracture risk, done by means of the FRAX calculator, and classification of women according to the level of risk could prove to be an effective method of limiting the negative effects of osteoporosis.
Trochimczuk R.,University of Bialystok |
Kuzmierowski T.,Lomza State University of Applied Sciences |
Anchimiuk P.,Non Public Health Care Institution Specialist Clinic Rehabilitacja
International Journal of Applied Mechanics and Engineering | Year: 2017
This paper defines the design assumptions for the construction of an original demonstration of a CPM device, based on which a solid virtual model will be created in a CAD software environment. The overall dimensions and other input parameters for the design were determined for the entire patient population according to an anatomical atlas of human measures. The medical and physiotherapeutic community were also consulted with respect to the proposed engineering solutions. The virtual model of the CPM device that will be created will be used for computer simulations of changes in motion parameters as a function of time, accounting for loads and static states. The results obtained from computer simulation will be used to confirm the correctness of the design adopted assumptions and of the accepted structure of the CPM mechanism, and potentially to introduce necessary corrections. They will also provide a basis for the development of a control strategy for the laboratory prototype and for the selection of the strategy of the patient's rehabilitation in the future. This paper will be supplemented with identification of directions of further research. © 2017 R. Trochimczuk et al.
Sienkiewicz J.J.,Lomza State University of Applied Sciences |
Wesolowski A.,University of Warmia and Mazury |
Stankiewicz W.,Military Institute of Hygiene and Epidemiology |
Kotowski R.,Polish Japanese Academy of Information Technology
Journal of Food Science and Technology | Year: 2017
This study proposes the destruction of pathogenic bacteria with the use of ultrasound waves because the more commonly used thermal processing methods often result in lowering the nutritional value of food. The study presents the impact of ultrasound of 20, 40 and 100 kHz frequencies and the power of 10.5 W/cm2 on the growth of the strain of Salmonella enterica subs. typhimurium. The tests were carried out both in chilled and non-chilled treatment mediums, with an average bacterial population >105 and >108 CFU/cm3. The total inactivation of Salmonella spp. was observed in the tests in the low-population non-chilled treatment medium after sonication at 20 and 40 kHz for 30 min, and in high bacterial population at 20 kHz for 30 min. A reduction in the average number of bacteria was reported in the low-population non-chilled medium after 15 min of sonication at 20, 40 and 100 kHz; after 15 min of sonication at 20 and 100 kHz of the material of high bacterial population; and in the low-population chilled treatment mediums after 15 and 30 min at 20 kHz. The samples with inactivated bacteria and those with reduced bacterial counts maintained the same levels when stored at 4 °C for 24 and 48 h. Bacteria inactivation obtained after sonication lasted for up to 48 h in storage at 21 °C. For the samples with reduced bacterial counts stored at 21 °C, a rise in the average number of bacteria was recorded. © 2017, Association of Food Scientists & Technologists (India).
Knapp M.,Medical University of Bialystok |
Gorski J.,Medical University of Bialystok |
Gorski J.,Lomza State University of Applied Sciences
Journal of Physiology and Pharmacology | Year: 2017
For 40 years, the enzyme hormone sensitive lipase was considered to hydrolyze the first ester bond of the triacylglycerol moiety and thus initiate hydrolysis. However, 12 years ago a new lipolytic enzyme, termed adipose triglyceride lipase was discovered. It was further shown that the process of lipolysis of triacylglycerol to diacylglycerol and fatty acid is initiated by adipose triglyceride lipase and not by hormone sensitive lipase, responsible for hydrolysis of diacylglycerol to monoacyglycerol and fatty acid. Adipose triglyceride lipase is present in all types of cells containing neutral fat. The enzyme is activated by a protein called comparative gene identification-58 and inhibited by a protein called G0/G1 switch protein 2. It has also been discovered that perilipins, the main proteins coating lipid droplets in the cells, are involved in the process of triacylglycerol lipolysis. Five perilipins (1-5) were identified, however, up to now their role has been poorly assessed. In skeletal muscles, exercise and training affect the mRNA expression and protein content of adipose triglyceride lipase, comparative gene identification-58, G0/G1 switch protein 2, perilipin 2 and 5. The effect of exercise/training depends on exercise intensity and type of muscle fiber. An interaction between comparative gene identification-58 and adipose triglyceride lipase seems to be responsible for the enzyme activation during contractile activity. Adipose triglyceride lipase is also responsible for the activation of the first step of triacylglycerol lipolysis in the heart. There is substantial evidence that cardiac triacylglycerol metabolism affects the function of the heart. ATGL gene mutations leads to the development of neutral lipid storage diseases. © 2017, Polish Physiological Society. All rights reserved.
Pauk J.,University of Bialystok |
Kuzmierowski T.,Lomza State University of Applied Sciences |
Ostaszewski M.,University of Bialystok |
Daunoraviciene K.,Vilnius Gediminas Technical University
Journal of Vibroengineering | Year: 2017
This study presents data on the application of two different processing techniques of foot parameters and the comparison of their validity and reliability in adults. Twenty-four healthy participants volunteered took part in the study. Three digital scans were obtained from each participant by one experienced investigator. The foot parameters were: Clarke index, ‘KY’ index of Sztriter-Godunov, heel angle and Wejsflog index. The parameters were identified into two ways: manually using software SolidWorks and by a new computer-aided system. The results of the Spearman's rank correlation suggest a strong positive relationship between parameters obtained from the computer-aided system and manually counted (R > 0.9). The current study suggests that computer-aided system is a practical tool for foot type assessment in adults and could be recommended for both research and clinical applications. © JVE INTERNATIONAL LTD.
Stachelska M.A.,Lomza State University of Applied Sciences
Journal of Animal and Feed Sciences | Year: 2017
The aim of the present study was to develop a highly sensitive and specific TaqMan probe with a set of primers for detection of pathogenic Yersinia enterocolitica strains and to eliminate the pre-PCR enrichment step in the real-time PCR (qPCR). A newly developed qPCR assay which is sensitive and specific for quick and reliable quantitative assessment of Y. enterocolitica present in artificially contaminated raw pork meat samples is described. This protocol involves the qPCR method with a TaqMan probe. The primers and probe were designed on the base of locus-tag CH49-3099 gene. This protocol appeared to be reliable for both intended applications: 1. identification and quantification of Y. enterocolitica in artificially and naturally contaminated raw pork meat and 2. establishment of growth potentials of different serotypes of Y. enterocolitica in raw meat at the usually used storage temperatures. This developed method makes it possible to eliminate the pre-PCR enrichment step enabling for the rapid assessment of meat-related consumer exposure to this pathogen.
Szczebiot R.,Lomza State University of Applied Sciences |
Cieslik S.,University of Technology and Life Sciences in Bydgoszcz
Przeglad Elektrotechniczny | Year: 2011
The paper presents a modelling method of optimal connection of wind generators to a medium voltage (MV) power grid taking into account minimum active power losses. A genetic algorithm was applied to optimize active power losses in the power grid.
PubMed | Medical University of Bialystok and Lomza State University of Applied Sciences
Type: Journal Article | Journal: Acta biochimica Polonica | Year: 2016
Nowadays non-alcoholic fatty liver disease (NAFLD) is becoming the most common chronic liver pathology both in adults and children. NAFLD manifestation ranges from a simple liver steatosis to steatohepatitis (nonalcoholic steatohepatitis - NASH), which may progress to advanced fibrosis, cirrhosis and end-stage liver disease. Due to the coexistence of visceral obesity, insulin resistance and dyslipidemia, NAFLD is considered to be the hepatic manifestation of metabolic syndrome. In recent years, in the pathogenesis of metabolic syndrome, type 2 diabetes mellitus, cardiovascular disease and also NAFLD, more and more attention has been paid to the so-called organokines, proteins with both paracrine or/and endocrine activities. These include most known adipokines (mainly produced by adipose tissue), myokines (mainly produced by skeletal muscles) and hepatokines exclusively or predominantly produced by the liver. It was shown that the liver may affect the lipids and glucose metabolism by hepatokines released into the blood and NAFLD seems to be associated with altered hepatokines production. Fetuin-A, fibroblast growth factor-21 (FGF-21), selenoprotein P, sex hormone-binding globulin (SHBG), angiopoietin-related growth factor (also known as angiopoietin-related protein 6) and leukocyte derived chemotaxin 2 (LECT2) are considered as the most important hepatokines. In this review, we provide an overview of the main hepatokines and we summarize the association of liver-derived proteins with the development and progression of NAFLD.
Piasecki W.,University of Physical Education in Warsaw |
Charmas R.,Lomza State University of Applied Sciences
Adsorption | Year: 2016
We developed a theoretical model which describes the influence of the applied potential to the wall of an oxide nanochannel on the diffuse layer potential in the solution filling the nanopore. It was assumed that the surface of oxide is energetically heterogeneous and electrolyte ions from the solution can adsorb on channel walls. We performed calculations for two oxides: SiO2 and Al2O3. It was found that energetically heterogeneous oxide surfaces strongly suppress gating potential. Moreover, taking into account ion adsorption considerably increased the electrokinetic potential and reduced the influence of applied potential on the electric double layer in the solution. The density of surface sites is the key parameter in the modeling of oxide nanochannels. Low density of surface hydroxyl groups significantly increases susceptibility on electrofluidic gating. © 2016 The Author(s)
Lewicki P.,Lomza State University of Applied Sciences
Zywnosc. Nauka. Technologia. Jakosc/Food. Science Technology. Quality | Year: 2010
In the paper, the changes are presented that occur in seeds whilst they sprout, as is the connection between the sprouting seeds and the chemical composition thereof. The sprouts have been proved to be a rich source of basic food components such as amino acids, vitamins, minerals, unsaturated fatty acids, and dietary fibre. Moreover, the sprouts contain those compounds, which are absent, or occur in small amounts in other food products. First of all, they are compounds showing antioxidant activity. Furthermore, some examples are given to demonstrate the impact of technological parameters and composition of moisturizing fluid on the sprouting process and on the chemical composition of sprouts. The production of sprouts is simple and makes it possible to produce sprouts containing abounding amounts of a required component or components. The microbiological quality of sprouts can constitute a problem both during the production process and when selling sprouts. Hence, the sprouts should be deemed as a raw material for processing, such as drying, freezing, and preserving in hermetically sealed cans, or as a source of natural components that are essential for diet.