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Brusciano, Italy

Montaldo L.,The Second University of Naples | Montaldo P.,The Second University of Naples | Papa A.,University of Naples Federico II | Caramico N.,The Second University of Naples | Toro G.,Local Health Unit Naples
Diabetic Medicine | Year: 2010

Aims To assess oral status in a sample of Type-2 diabetic patients before and after therapy with saliva substitutes and oral status in a control group of diabetic patients who were not given saliva substitutes.Methods Salivary flow rate was determined in 134 patients (mean age 47.9-±-2.9-years) with Type-2 diabetes. Mean salivary rate was significantly low compared with a healthy control group. The sample of 134 patients was randomly divided into two groups of 67 people each. One group was given immunologically active salivary substitutes for 6-months, the other group was given nothing. Each patient of the two groups underwent a dental and periodontal examination at the beginning of the study and 6-months later.Results As regards carious teeth and teeth loss, there was no statistical difference between the first group after 6-months of treatment with salivary substitutes and the control group (P->-0.01). Salivary substitutes did not significantly reduce the periodontal disease (P > 0.01). In the group treated with salivary substitutes, after 6-months of therapy, the average dental plaque index decreased from 2.3-±-0.73 to 1.6-±-0.56, patients with gingivitis decreased from 66 to 43% and patients with positive yeast counts decreased from 60 to 37%. These differences were statistically significant (P < 0.01).Conclusions In Type-2 diabetes, in the case of hyposalivation, a therapy with immunologically active saliva substitutes can be of help in reducing the amount of plaque, gingivitis and positive yeast counts. © 2010 The Authors. Diabetic Medicine © 2010 Diabetes UK. Source

Minicozzi P.,Analytical Epidemiology and Health Impact Unit | Kaleci S.,University of Modena and Reggio Emilia | Maffei S.,University of Modena and Reggio Emilia | Allemani C.,London School of Hygiene and Tropical Medicine | And 10 more authors.
European Journal of Public Health | Year: 2013

We analysed presentation, treatment and survival in a representative population-based sample of 3753 Italian colorectal cancer cases, diagnosed 2003-05: 70% were >65 years, 44% stage I-II, 27% stage IV and 92% received surgery. Chemotherapy was given to 58% of stage III colon cases, radiotherapy to 25% of rectal cases. Four percent of surgical cases underwent endoscopic polypectomy, and in 57% â 11 lymph nodes were examined. Five-year relative survival was good (60%), independent of sex and site. Adherence to treatment guidelines was satisfactory, but wider use of faecal blood testing and colonoscopy will anticipate stage at diagnosis and likely improve survival. © 2013 The Author. Source

Girasole M.,University of Naples Federico II | Chirollo C.,University of Naples Federico II | Ceruso M.,University of Naples Federico II | Vollano L.,University of Naples Federico II | And 2 more authors.
Italian Journal of Food Safety | Year: 2015

Animal killing for food production and the related operations are events that may induce pain, stress, fear and other forms of suffering to the animals. To face this problem and guarantee the animal welfare, the EU has adopted the Regulation (EC) N. 1099/2009 on the protection of animals at the time of killing. Electrical water bath stunning is one of the methods used in commercial slaughterhouses to protect poultry welfare. In particular, this method induces unconsciousness into the birds due to run of electrical current through the head and body. The aim of the present work was to find an optimal setting of electrical parameters to obtain an effective water bath stunning in a commercial poultry slaughterhouse. Moreover, the influence of the tested electrical parameters on meat quality was evaluated. All the experiments confirmed that high stunning frequencies induce a lower occurrence of lesions on carcasses but, on the other hand, require greater current intensities to be effective. A frequency of 750 Hz and an average current intensity of 200 mA for each bird in the water bath resulted as the best combination of electrical parameters to obtain a proper stunning without any consequence on the meat quality. © 2015, Page Press Publications. All rights reserved. Source

Minicozzi P.,Analytical Epidemiology and Health Impact Unit | Berrino F.,Fondazione Istituto Nazionale Dei Tumori | Sebastiani F.,University of Modena and Reggio Emilia | Falcini F.,Romagna Cancer Registry | And 14 more authors.
European Journal of Cancer | Year: 2013

Purpose We investigated the effect of fasting blood glucose and body mass index (BMI) at diagnosis on risk of breast cancer death for cases diagnosed in five Italian cancer registries in 2003-2005 and followed up to the end of 2008. Methods For 1607 Italian women (≥15 years) with information on BMI or blood glucose or diabetes, we analysed the risk of breast cancer death in relation to glucose tertiles (≤84.0, 84.1-94.0, >94.0 mg/dl) plus diabetic and unspecified categories; BMI tertiles (≤23.4, 23.5-27.3, >27.3 kg/m 2, unspecified), stage (T1-3N0M0, T1-3N+M0 plus T4anyNM0, M1, unspecified), oestrogen (ER) and progesterone (PR) status (ER+PR+, ER-PR-, ER and PR unspecified, other), age, chemotherapy and endocrine therapy, using multiple regression models. Separate models for ER+PR+ and ER-PR- cases were also run. Results Patients often had T1-3N0M0, ER+PR+ cancers and received chemotherapy or endocrine therapy; only 6% were M1 and 17% ER-PR-. Diabetic patients were older and had more often high BMI (>27 kg/m2), ER-PR-, M1 cancers than other patients. For ER+PR+ cases, with adjustment for other variables, breast cancer mortality was higher in women with high BMI than those with BMI 23.5-27.3 kg/m2 (hazard ratio (HR) = 2.9, 95% confidence interval (CI) 1.2-6.9). Breast cancer mortality was also higher in women with high (>94 mg/dl) blood glucose compared to those with glucose 84.1-94.0 mg/dl (HR = 2.6, 95% CI 1.2-5.7). Conclusion Our results provide evidence that in ER+PR+ patients, high blood glucose and high BMI are independently associated with increased risk of breast cancer death. Detection and correction of these factors in such patients may improve prognosis. © 2013 The Authors. Published by Elsevier Ltd. All rights reserved. Source

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